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When medicines cause harm: learning from the DES disaster episode artwork

Sep 29, 2026 35 min

When medicines cause harm: learning from the DES disaster

from DTB Podcast Hosted by BMJ Group

The DTB podcast returns with a new format, and a new host: Dr Hannah Harris, urgent care GP and Clinical Editor of DTB. In this episode, Hannah is joined by Professor Barbara Mintzes and Carol Devine, a patient and second-generation victim of Diethylstilbestrol (DES), to examine the long-term, multigenerational impacts of this synthetic oestrogen prescribed in pregnancy to prevent miscarriage from the 1940s to 1980s. They discuss why DES continued to be prescribed despite early proof of inefficacy and harm, Carol’s personal health struggle as a "DES Daughter," and the ongoing fight for government recognition and patient care. This episode also highlights key clinical updates from the September issue of the Drug and Therapeutics Bulletin, including a commentary by the new Editor-in-Chief, Dr Gordon Mallarkey, on precision medicine in COPD, non-hormonal treatments for polyendocrine metabolic ovarian syndrome, diagnosis of spasticity, and continuous glucose monitoring in type 2 diabetes. Read the issue on our website: https://dtb.bmj.com/content/64/9. We would love to hear from you with comments or questions via email ([email protected]), or you can find us on X with the handle @DTB_BMJ, and also LinkedIn and Facebook under “Pharmacy at BMJ Group”. The DTB Podcast is hosted by Hannah Harris. It is produced by Hannah Harris and Letícia Amorim. It is edited by Letícia Amorim.

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When medicines cause harm: learning from the DES disaster

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