When Supplements Make You Feel Worse (And Why It’s Not Random) | Dr. Tyler

EPISODE · Apr 8, 2026 · 1H 14M

When Supplements Make You Feel Worse (And Why It’s Not Random) | Dr. Tyler

from The Evolving Wellness Podcast with Sarah Kleiner Wellness · host Sarah Kleiner

Host Sarah interviews Dr. Tyler Panner, a PhD in cell biology and pharmacology, about why supplements can be life-changing for some people and harmful for others due to bioindividuality, genetics, and “terrain.” They discuss how stacking polyphenol supplements (e.g., curcumin, quercetin, resveratrol) can inhibit neurotransmitter breakdown and make adrenaline linger, worsening restlessness, anxiety, sleep, and irritability, and how concentrated products can also chelate iron and copper. They cover sulfur/sulfite sensitivity, histamine and glutamate “gas pedals,” confusing supplement blends, and misattributing adverse reactions to “detox.” The conversation critiques absolutist online supplement advice, fear-based content (including mold and oxalates), and highlights the need for supplement pharmacology, testing, and careful dosing, noting some people improve by removing the wrong supplements rather than adding more.Connect with Tyler Panzner:https://www.instagram.com/drtylerpanzner _________Sponsored By:→ VivaRays | This episode is sponsored by VivaRays - VivaRays Blue - code YOGI https://vivarays.com/→ Troscriptions | For an exclusive offer, go to https://www.troscriptions.com/SARAHK for 10% off your first non subscription order._________Timestamp:00:00 Red Light Office Prep00:49 Podcast Intro and Disclaimers03:28 Time Change Morning Strategy05:14 Pre Sunrise Routine Tools08:06 Lux Timer and Light Breaks10:04 Lux Thresholds Explained14:42 Light Boxes Pros and Cons17:56 Spring Skin Sun Prep19:43 Nutrition and Burn Risk23:01 Sequential Sunlight and UVA26:48 Metabolism Skin Benefits28:01 New Topic Methylene Blue28:26 Methylene Blue Use Cases29:12 Cellulite as Energy Loss30:59 Spring UVB Vitamin D Basics32:44 Microdosing Sun Exposure34:23 UV Index and Skin Type36:00 Blue Blockers Reality Check37:27 Cold Plunge for Melanin40:16 Shade Infrared Office Fixes43:20 Evening Routine and Eating45:35 Lux Rules and Glasses49:56 Sleep Debt and Body Clocks51:28 Programs and Final Wrap——— This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________Get all my free guides and product recommendations to get started on your journey!https://www.sarahkleinerwellness.com/all-free-resourcesCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) -  https://www.sarahkleinerwellness.com/coursesMy free product guide with all product recommendations and discount codes:https://www.canva.com/design/DAF7mlgZpJI/xVyE4tiQFEWJmh_Xwx8Kbw/view?utm_content=DAF7mlgZpJIFree Webinar on Light & Health (includes free light bulb guide) - https://www.sarahkleinerwellness.com/mycircadianapp-free-webinarGet Early Access to Podcast Episodes & my Seasonal Food Course + UVB+Red Light Therapy course for free -  https://open.substack.com/pub/sarahkleinerwellness/p/uvbred-light-protocol?r=5eztl9&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

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When Supplements Make You Feel Worse (And Why It’s Not Random) | Dr. Tyler

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