When Tech Meets the Mission: How Ike Anand Is Reimagining St. Jude for the Digital Age

When Ike Anand flew into Memphis in the summer of 2020—just one of four passengers on an otherwise empty plane, double-masked with a face shield—he was answering what he calls a calling he couldn’t ignore.  After 15 years scaling Expedia’s global network in Seattle, Anand left the tech world to become the seventh CEO of ALSAC, the fundraising arm of St. Jude Children’s Research Hospital. Now he’s leading the charge on a $12.9 billion strategic plan while reimagining what it means to be a tech-forward nonprofit in an age of viral content and AI-driven personalization.In this conversation, Anand reveals how speed, data, and culture are reshaping one of America’s most beloved charitable institutions. It’s Ike Anand on The Business of Giving.