EPISODE · Nov 8, 2025 · 12 MIN
When Time Mutates: The Paternal Age Effect
from The Deep Dive Lab: Unraveling Materials Science · host Son Hoang
What if the real “biological clock” isn’t ticking in the womb… but in the testes? 🧬A new Nature (2025) study — “Sperm sequencing reveals extensive positive selection in the male germline” — has turned our understanding of fatherhood and genetics upside down.Inside every man’s testes, a microscopic Darwinian struggle is taking place: certain sperm stem cells mutate and outcompete others, multiplying as men age — and quietly spreading harmful mutations.🎙️ In this episode, we unpack:How sperm stem cells protect — yet betray — our DNA.The “selfish” evolution within the germline.Why older fathers face 2–3× higher mutation risk.And how this process is subtly reshaping the human gene pool.👉 Tune in to explore the hidden biological clock of fathers — and what it means for our future.📚 Source: Sperm sequencing reveals extensive positive selection in the male germline. Nature, 2025.#Genetics #SciencePodcast #DNA #Nature #Evolution #Fatherhood #PaternalAge #Genomics #ScienceExplained 🧬
What this episode covers
What if the real “biological clock” isn’t ticking in the womb… but in the testes? 🧬A new Nature (2025) study — “Sperm sequencing reveals extensive positive selection in the male germline” — has turned our understanding of fatherhood and genetics upside down.Inside every man’s testes, a microscopic Darwinian struggle is taking place: certain sperm stem cells mutate and outcompete others, multiplying as men age — and quietly spreading harmful mutations.🎙️ In this episode, we unpack:How sperm stem cells protect — yet betray — our DNA.The “selfish” evolution within the germline.Why older fathers face 2–3× higher mutation risk.And how this process is subtly reshaping the human gene pool.👉 Tune in to explore the hidden biological clock of fathers — and what it means for our future.📚 Source: Sperm sequencing reveals extensive positive selection in the male germline. Nature, 2025.#Genetics #SciencePodcast #DNA #Nature #Evolution #Fatherhood #PaternalAge #Genomics #ScienceExplained 🧬
NOW PLAYING
When Time Mutates: The Paternal Age Effect
No transcript for this episode yet
Similar Episodes
No similar episodes found.
Similar Podcasts
No similar podcasts found.