When Ulcers Lie: Unmasking Vasculitis in the Diabetic Foot

This episode breaks down uncontrolled vasculitis — inflammation of blood vessels that can mimic diabetic, arterial, or pressure ulcers. It reviews pathophysiology (immune complex and ANCA‑mediated mechanisms), types by vessel size, key signs (palpable purpura, necrotic toes, sudden ischemia), and essential diagnostics (ESR/CRP, ANCA, complement, urinalysis, biopsy, CTA). It highlights urgent management (high‑dose steroids, immunosuppressants, biologics), wound‑care cautions (avoid unnecessary debridement in ischemic vasculitic ulcers), and the importance of early vascular and autoimmune referral to prevent organ damage and amputation.