Whipple's Disease

Whipple's Disease explained, including microbiology of T.Whipplei and Whipple's Disease pathology. We look at the symptoms of Whipple's Disease including Classic and Local forms, as well as Whipple's Disease diagnosis and treatment. PDFs Available here: https://rhesusmedicine.com/Consider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Patreon: https://www.patreon.com/rhesusmedicineBuy Us A Coffee!: https://www.buymeacoffee.com/rhesusmedicineTimestamps:0:00 What is Whipple’s Disease?0:20 Whipple's Disease - Trophyerma Whipplei Microbiology0:51 Whipple’s Disease Pathology2:35 Whipple’s Disease Symptoms5:45 Whipple’s Disease Diagnosis7:13 Whipple’s Disease Treatment ReferencesDolmans, R.A.V., Boel, C.H., Lacle, M.M. & Kusters, J.G., 2017. Clinical manifestations, treatment, and diagnosis of Tropheryma whipplei infections. Clinical Microbiology Reviews, 30(2), pp.529-555. [online] Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC5355640/ PubMed+1MSD Manuals, 2025. Whipple disease. [online] Available at: https://www.msdmanuals.com/professional/gastrointestinal-disorders/malabsorption-syndromes/whipple-disease NCBIBMJ Best Practice, 2025. Aetiology – Whipple disease. [online] Available at: https://bestpractice.bmj.com/topics/en-gb/467/aetiologyMount Sinai Health System, 2025. Supranuclear ophthalmoplegia. [online] Available at: https://www.mountsinai.org/health-library/diseases-conditions/supranuclear-ophthalmoplegiaMarth, T., Moos, V., Müller, C. et al., 2016. Tropheryma whipplei infection and Whipple's disease. The Lancet Infectious Diseases, 16(3):e13-22. [online] Available at: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(15)00537-X/abstract PubMed+1Please remember this podcast and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice.