Why are people flying to Korea to inject salmon sperm in their faces?

What is PDRN? You've probably seen the four letters on serum bottles, sheet masks and even lip balms — or heard them on TikTok. PDRN stands for polydeoxyribonucleotide and typically refers to a DNA fragment that's often, but not always, derived from salmon sperm and most commonly found in K-Beauty. Of course, on social media, PDRN has an obvious shock value to it, which has led to an onslaught of posts in which lines like, "I just got salmon sperm injected into my face," provide perfect hooks to start videos. In this week's episode of the Glossy Beauty Podcast, co-host Sara Spruch-Feiner explores what PDRN is, what it purports to do for the skin, how it got so popular and how it is expanding beyond Korean beauty. To explore the topic, Spruch-Feiner speaks with New York City-based dermatologist Dr. David Kim; the former editor-in-chief of Allure magazine and fractional CMO for K-Beauty distributor Landing International, Michelle Lee; and the founder of Rodial, Maria Hatzistefanis.