Why CoVid19 Gravely Infects Fewer Children Than Adults episode artwork

EPISODE · May 29, 2020 · 0 MIN

Why CoVid19 Gravely Infects Fewer Children Than Adults

from Dr. Howard Smith OnCall · host Howard G. Smith MD, AM

  Vidcast:  https://youtu.be/jkCdLaRoj9M   Expression of the gene that triggers ACE2 protein generation, the CoVid doorway into cells, is reduced in kids compared with adults.  Pediatricians and geneticists at New York’s Mount Sinai Hospital report this finding after studying 305 subjects 4 to 60 years of age.   ACE2 gene expression in nasal tissue is the lowest in children age 10 or under.  Gene expression increases with age and appears to level off above the age of 25.    Though children may be less likely to develop clinical infections, they do seem to carry infectious virus that they may spread to others.  The reason for this pediatric carrier state is yet unknown.   https://jamanetwork.com/journals/jama/fullarticle/2766524   #covid #ace2 #children  

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