Why Data Governance Is the Key to AI Biosecurity, with Jassi Pannu and Doni Bloomfield

Why Data Governance Is the Key to AI Biosecurity, with Jassi Pannu and Doni Bloomfield Alan Rozenshtein, research director at Lawfare, spoke with Jassi Pannu, assistant professor at the Johns Hopkins Bloomberg School of Public Health and senior scholar at the Johns Hopkins Center for Health Security, and Doni Bloomfield, associate professor of law at Fordham Law School, about their proposed framework for governing biological data to reduce AI-enabled biosecurity risks. The conversation covered the origins of the proposal in the 50th anniversary of the 1975 Asilomar conference on recombinant DNA; the distinction between general-purpose AI models and biology-specific foundation models like genomic language models; the biosecurity threats posed by AI, including uplift of novice actors and raising the ceiling of expert capabilities; the proposed biosecurity data levels (BDL 0-4) framework and how it draws on precedents from biosafety levels and genetic privacy regulation; the challenge of capabilities-based rather than pathogen-based data classification; the institutional and regulatory mechanisms for enforcement, including the role of NIH grant conditions and a proposed mandatory federal regime; international collaboration and the importance of U.S. leadership given that most high-tier data is generated domestically; the relationship between the proposal and open-source biological AI development; and the offense-defense imbalance in biosecurity and the case for mandatory gene synthesis screening. Mentioned in this episode:Jassi Pannu and Doni Bloomfield et al., "Biological data governance in an age of AI," Science (2026)Jassi Pannu, Doni Bloomfield, et al., "Dual-use capabilities of concern of biological AI models," PLOS Computational Biology (2025)Dario Amodei, "The Adolescence of Technology" (2026)The Genesis Mission Executive Order (November 2025) Hosted on Acast. See acast.com/privacy for more information.