Why GLP-1 Withdrawal Trials Fail — and Why Cardiometabolic Care Must Look Different

from VAT Trap · host Dr Edward Leatham

A 2026 BMJ systematic review confirms that weight regain is the rule after stopping pharmacological weight-management therapy. Across drug classes, most lost weight is regained within 24 months, with parallel loss of metabolic benefit. This reflects biological defence of adiposity, not patient failure.Blog

Episode metadata supplied by the publisher feed · Published Jan 20, 2026

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Why GLP-1 Withdrawal Trials Fail — and Why Cardiometabolic Care Must Look Different

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