EPISODE · Nov 6, 2025 · 11 MIN
Why is it so hard to lose weight?
from Modern Metabolic Health with Dr. Lindsay Ogle, MD · host Lindsay Ogle, MD
We unpack why weight loss is hard, how set point and hunger hormones push back, and what tools make maintenance possible. We move from biology and environment to medications, mindset, and practical support so you can protect your metabolic health for the long term.• evolutionary biology driving energy conservation• modern food environment increasing calorie density and reward• weight set point and metabolic adaptation mechanisms• evidence from The Biggest Loser metabolic study• ghrelin and hunger increases after weight loss• role of anti-obesity medications for chronic management• mindset shift from motivation to dedication in maintenance• value of coaching, groups, and medical supportPlease share with a friend, family member, or colleaguePlease subscribe and write a reviewThis will help others find the podcast so they may also improve their metabolic health👩🏼⚕️ Live in Missouri? Want to be my patient?Telehealth clinic: https://missourimetabolichealth.com🥑 Have questions you want answered on the podcast? Email [email protected]✨Freebies✨Anti-Obesity Medication OptionsHow To Prevent DiabetesHealthy Habits WorkbookPreventative Health Checklist🤗 Socials:Instagram: https://www.instagram.com/dr.lindsayogle/TikTok: https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1YouTube: https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg
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We unpack why weight loss is hard, how set point and hunger hormones push back, and what tools make maintenance possible. We move from biology and environment to medications, mindset, and practical support so you can protect your metabolic health for the long term. • evolutionary biology driving energy conservation • modern food environment increasing calorie density and reward • weight set point and metabolic adaptation mechanisms • evidence from The Biggest Loser metabolic study • ghrelin ...
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Why is it so hard to lose weight?
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