Why Matt Kaeberlein Says Most Longevity Advice Is Wrong episode artwork

EPISODE · Jul 1, 2025 · 53 MIN

Why Matt Kaeberlein Says Most Longevity Advice Is Wrong

from The Neuro Experience · host Louisa Nicola & Pursuit Network

Dr. Matt Kaeberlein is one of the world’s most respected scientists in the field of aging biology. In this episode, we unpack the real science of longevity — from mTOR inhibition and rapamycin to calorie restriction, biomarkers of aging, and what most people get wrong about lifespan vs healthspan. We go beyond the hype to ask: What actually works? What’s still theoretical? And where is the frontier of human aging research heading? Topics we cover: The biology of aging: mTOR, autophagy, senescence Rapamycin in humans: What we know and don’t Why extending healthspan matters more than living longer Matt’s views on supplements, diet, and biomarkers The most misunderstood concepts in anti-aging Referenced studies include: Dog Aging Project Interventions Testing Program Rapamycin human trial data *** I’m Louisa Nicola — clinical neuophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Matt Kaeberlein is one of the world’s most respected scientists in the field of aging biology. In this episode, we unpack the real science of longevity — from mTOR inhibition and rapamycin to calorie restriction, biomarkers of aging, and what most people get wrong about lifespan vs healthspan. We go beyond the hype to ask: What actually works? What’s still theoretical? And where is the frontier of human aging research heading? Topics we cover: The biology of aging: mTOR, autophagy, senescence Rapamycin in humans: What we know and don’t Why extending healthspan matters more than living longer Matt’s views on supplements, diet, and biomarkers The most misunderstood concepts in anti-aging Referenced studies include: Dog Aging Project Interventions Testing Program Rapamycin human trial data *** I’m Louisa Nicola — clinical neuophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

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Why Matt Kaeberlein Says Most Longevity Advice Is Wrong

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This episode was published on July 1, 2025.

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Dr. Matt Kaeberlein is one of the world’s most respected scientists in the field of aging biology. In this episode, we unpack the real science of longevity — from mTOR inhibition and rapamycin to calorie restriction, biomarkers of aging, and what...

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