Why Most Probiotics Don’t Work (And What to Do Instead) - Dr Colleen Cutcliffe

Episode: Are Your Probiotics Actually Doing Anything? In this episode, I sit down with Dr. Colleen Cutcliffe, PhD biochemist and CEO of Pendulum, to break down the real science of the microbiome — and why most probiotic supplements fall short. We cover: What the microbiome actually is The difference between probiotics, prebiotics, and postbiotics Why most probiotics never reach your gut The importance of Akkermansia muciniphila and Clostridium butyricum What causes leaky gut and how to fix it How fiber and polyphenols fuel your microbiome Why your gut impacts blood sugar, cravings, and energy This isn’t surface-level advice. It’s a deep dive into what the science really says — and what most supplement companies won’t tell you. If you’ve ever struggled with digestion, energy crashes, or food sensitivities, this episode is a must-watch. Guest: Dr. Colleen Cutcliffe — Co-Founder and CEO of Pendulum Host: Michael Tchao (@michaeltchao) Subscribe for more science-backed conversations at the intersection of food, health, and function. 🎁 Special Offer: For 20% off Pendulum membership first orders, use code MICHAEL20 👉 Visit PendulumLife.com