Why Progesterone Doesn’t Work for Everyone

from Dr. Brendan McCarthy · host Dr. Brendan McCarthy

Welcome to the podcast with Dr. Brendan McCarthy! Today he addresses a topic many women have been waiting to hear more about: why some people don't tolerate progesterone well. Often overlooked in both conventional and alternative medicine, "reverse responders" experience heightened anxiety, insomnia, or mood shifts when taking progesterone — a reaction that defies the standard approach. Dr. McCarthy explores the science behind these responses, the emotional toll of being dismissed, and why deeper investigation and individualized care are essential. This episode is the first in a multi-part series where Dr. McCarthy shares: • What progesterone is supposed to do in the body • Why it can sometimes cause adverse effects • The importance of understanding hormone-brain interactions • A more compassionate and evidence-based approach to hormone therapy If you or someone you love has struggled with hormone treatments, this episode offers insight, validation, and a path forward. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com

Episode metadata supplied by the publisher feed · Published Apr 4, 2025

What this episode covers

Welcome to the podcast with Dr. Brendan McCarthy! Today he addresses a topic many women have been waiting to hear more about: why some people don't tolerate progesterone well. Often overlooked in both conventional and alternative medicine, "reverse responders" experience heightened anxiety, insomnia, or mood shifts when taking progesterone — a reaction that defies the standard approach. Dr. McCarthy explores the science behind these responses, the emotional toll of being dismissed, and why deeper investigation and individualized care are essential. This episode is the first in a multi-part series where Dr. McCarthy shares:• What progesterone is supposed to do in the body• Why it can sometimes cause adverse effects• The importance of understanding hormone-brain interactions• A more compassionate and evidence-based approach to hormone therapy If you or someone you love has struggled with hormone treatments, this episode offers insight, validation, and a path forward. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com

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Why Progesterone Doesn’t Work for Everyone

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This episode is 18 minutes long.

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This episode was published on April 4, 2025.

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