Why Progesterone Makes Some Women Feel Worse — And What to Do Instead

Why does progesterone make some women feel calm and sleep deeply — while others feel anxious, depressed, or even suicidal?In this powerful episode of Midlife Re-Alignment, Esther Blum is joined by board-certified OB-GYN Dr. Anat Sapan to unpack the truth about progesterone in perimenopause and menopause.They break down:Why progesterone is the first hormone to decline in perimenopauseThe difference between progesterone and synthetic progestinsWhy some women experience progesterone intoleranceOral vs topical progesterone (and which helps sleep best)How progesterone affects anxiety, GABA, and allopregnanoloneWhether topical progesterone protects the uterusThe role of liver detox, receptor function, iodine, and endocrine disruptorsWhy progesterone may help breast tenderness, neuropathy, cholesterol, and even nervous system repairIf you’ve struggled with Prometrium side effects, 3AM wakeups, mood swings, or conflicting advice about hormone therapy — this episode will change the way you understand progesterone forever.Connect with Dr. Anat:https://doctoranat.comConnect with EstherWebsite:⁠ estherblum.com⁠Instagram: @gorgeousestherDisclaimer: This podcast is for education only and is not medical advice.