Why Weight Loss Feels Impossible | Dr. Eric Trexler episode artwork

EPISODE · Aug 10, 2026 · 1H 13M

Why Weight Loss Feels Impossible | Dr. Eric Trexler

from RP Strength Podcast

Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition. Guest Links Dr. Eric Trexler's Links: Instagram: @trexlerfitness ResearchGate: Eric Trexler publications Research review: MASS Research Review Timestamps 00:00 Weight-loss non-responders and the laws of thermodynamics 03:22 Rare medical conditions and extreme hunger 06:34 Hunger genetics, GLP-1s, and learning empathy 12:15 Lipedema and regionally resistant fat 21:48 PCOS, hypothyroidism, and what they do to metabolism 31:08 Three reasons weight loss can feel impossible 36:34 Tracking errors and the classic underreporting study 46:08 Food-label and restaurant-calorie errors 50:33 Controlled diet research and metabolic adaptation 58:39 Support, adherence, and why consistently showing up works 01:03:14 GLP-1s, side effects, and personalized dosing 01:10:45 Aging, activity, stress, and the myth of the 40-year-old metabolism

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Why Weight Loss Feels Impossible | Dr. Eric Trexler

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