Why You Hate Uncertainty & The New Science of Living Longer episode artwork

EPISODE · May 11, 2026 · 49 MIN

Why You Hate Uncertainty & The New Science of Living Longer

from Something You Should Know · host Mike Carruthers | OmniCast Media

Have you ever struggled with a problem—only to have the answer suddenly appear when you stopped trying? It feels almost like magic, but it’s actually your brain working in a very specific way when you step back. https://drexel.edu/now/archive/2016/March/Insight_Correctness/ We all want to know what’s going to happen next. But life doesn’t work that way. In fact, the real challenge may not be uncertainty itself—but our growing discomfort with it. Simone Stolzoff, journalist and author of How to Not Know: The Value of Uncertainty in a World that Demands Answers (https://amzn.to/428rpWb), explains why we crave certainty, why that craving can make life harder, and how learning to tolerate—and even embrace—uncertainty can change the way you experience the world. You’ve probably heard that your health is shaped by both your genes and your lifestyle. But how much control do you really have? Are some outcomes unavoidable—or can your daily choices actually override genetic risk? Dr. Florence Comite, endocrinologist and expert in longevity and precision medicine, has spent decades studying how to optimize health at the individual level. In our conversation, she explains how genes influence your future, where they don’t, and how understanding your personal biology can help you make smarter decisions to improve health and extend lifespan. She is author of Invincible: Defy Your Genetic Destiny to Live Better, Longer (https://amzn.to/3Pir404). In the middle of a tense conversation, it’s easy for things to escalate quickly. But there’s a simple three-word phrase that can instantly shift the tone—turning conflict into something more productive and less combative. Source: Bill Jensen author of The Simplicity Survival Handbook (https://amzn.to/4thwWEX) PLEASE SUPPORT OUR SPONSORS AQUA TRU: Take the guesswork out of pure, great-tasting water. Head to ⁠⁠https://AquaTru.com⁠⁠ now and get 20% off your purifier using promo code SYSK. AquaTru even comes with a 30-day best-tasting water guarantee or your money back. RULA: This Mental Health Awareness Month, don’t just think about your mental health - actually take the step to take care of it. Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://Rula.com/sysk⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to get started. QUINCE: Refresh your everyday with luxury you will actual use! Go to ⁠⁠⁠⁠https://Quince.com/sysk⁠⁠⁠⁠ for free shipping on your order and 365-day returns. Now available in Canada, too! SHOPIFY: It's time to turn those "what ifs" into CHA CHING with Shopify Today! Sign up for your $1 per month trail and start selling today at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://Shopify.com/sysk⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Have you ever struggled with a problem—only to have the answer suddenly appear when you stopped trying? It feels almost like magic, but it’s actually your brain working in a very specific way when you step back. https://drexel.edu/now/archive/2016/March/Insight_Correctness/ We all want to know what’s going to happen next. But life doesn’t work that way. In fact, the real challenge may not be uncertainty itself—but our growing discomfort with it. Simone Stolzoff, journalist and author of How to Not Know: The Value of Uncertainty in a World that Demands Answers (https://amzn.to/428rpWb), explains why we crave certainty, why that craving can make life harder, and how learning to tolerate—and even embrace—uncertainty can change the way you experience the world. You’ve probably heard that your health is shaped by both your genes and your lifestyle. But how much control do you really have? Are some outcomes unavoidable—or can your daily choices actually override genetic risk? Dr. Florence Comite, endocrinologist and expert in longevity and precision medicine, has spent decades studying how to optimize health at the individual level. In our conversation, she explains how genes influence your future, where they don’t, and how understanding your personal biology can help you make smarter decisions to improve health and extend lifespan. She is author of Invincible: Defy Your Genetic Destiny to Live Better, Longer (https://amzn.to/3Pir404). In the middle of a tense conversation, it’s easy for things to escalate quickly. But there’s a simple three-word phrase that can instantly shift the tone—turning conflict into something more productive and less combative. Source: Bill Jensen author of The Simplicity Survival Handbook (https://amzn.to/4thwWEX) PLEASE SUPPORT OUR SPONSORS AQUA TRU: Take the guesswork out of pure, great-tasting water. Head to ⁠⁠https://AquaTru.com⁠⁠ now and get 20% off your purifier using promo code SYSK. AquaTru even comes with a 30-day best-tasting water guarantee or your money back. RULA: This Mental Health Awareness Month, don’t just think about your mental health - actually take the step to take care of it. Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://Rula.com/sysk⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to get started. QUINCE: Refresh your everyday with luxury you will actual use! Go to ⁠⁠⁠⁠https://Quince.com/sysk⁠⁠⁠⁠ for free shipping on your order and 365-day returns. Now available in Canada, too! SHOPIFY: It's time to turn those "what ifs" into CHA CHING with Shopify Today! Sign up for your $1 per month trail and start selling today at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://Shopify.com/sysk⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

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Why You Hate Uncertainty & The New Science of Living Longer

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Eat to Live Jenna Fuhrman, Dr. Fuhrman Our health is our most precious gift and smart nutrition can change your life. Each month, join Dr. Fuhrman and his daughter, Jenna Fuhrman as they discuss important topics in the world of nutrition. Eat to Live will change the way you eat and think about food. French Your Way Jessica: Native French teacher founder of French Your Way Boost your French listening skills and test your comprehension with this one of a kind series of podcasts. Get the chance to listen to a real conversation between native speakers talking at normal speed AND customise your learning experience through carefully designed sets of questions (2 levels of difficulty) available for download at www.frenchvoicespodcast.com. All interviews also come with the transcript. French teacher Jessica interviews native speakers of French from around the world who share a bit of their life and passion. Where else would you meet in one same place a French yoga teacher based in Melbourne, a soap manufacturer from Provence, or a couple cycling around the world? DIOSA. Carolina Sanper This podcast is a sacred space created by Carolina Sanper where you connect with your inner wisdom and embody your magnetic feminine power.It is the realization that the mystical realm is where you plant the seeds of your desired reality.It is a portal to your true essence: awareness, presence, and receiving with ease. Welcome home, DIOSA. 🖤 XXX Tech by SOVRYN Dr. Brian Sovryn The crossroads between technology, sensuality, and metaphysics - and the longest running anarchist podcast in the world! Brought to you by Dr. Brian Sovryn.

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This episode was published on May 11, 2026.

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Have you ever struggled with a problem—only to have the answer suddenly appear when you stopped trying? It feels almost like magic, but it’s actually your brain working in a very specific way when you step back....

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