Wilson's Disease (Hepatolenticular Degeneration)

Wilson's Disease explained (Hepatolenticular Degeneration), including its pathophysiology and genetics, signs and symptoms, diagnosis (with criteria!) and treatment options. Consider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Patreon: https://www.patreon.com/rhesusmedicineBuy Us A Coffee!: https://www.buymeacoffee.com/rhesusmedicineTimestamps:0:00 What is Wilson’s Disease0:21 Wilson’s Disease Pathophysiology2:06 Wilson’s Disease Symptoms3:37 Wilson’s Disease Causes4:07 Wilson’s Disease Diagnosis 5:46 Wilson’s Disease Criteria (Leipzig Score)6:20 Wilson’s Disease Treatment References:BMJ Best Practice (2024) Wilson’s Disease. Available at https://bestpractice.bmj.com/topics/en-gb/427/Larry E. Johnson - MSD Manual Pro (2023) Wilson Disease. Available at https://www.msdmanuals.com/professional/nutritional-disorders/mineral-deficiency-and-toxicity/wilson-diseaseGaillard F, Deng F, Weerakkody Y, et al. (2020) Face of the giant panda sign (midbrain). Available at https://radiopaedia.org/articles/face-of-the-giant-panda-sign-midbrainWu, Fei & Wang, Jing & Pu, Chunwen & Qiao, Liang & Jiang, Chunmeng (2015) Wilson’s Disease: A Comprehensive Review of the Molecular Mechanisms. Available at https://www.researchgate.net/figure/Copper-is-delivered-by-HCTR1-to-cytosol-where-it-mainly-binds-to-Atox1-Atox1-transfers_fig2_276910514Please remember this podcast and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice.