Wired for the Light

This release contains only the music track from Base by Base Episode 375. Song title: Wired for the LightOriginal Base by Base episode: 375: Biallelic DSCAM LoF: a syndromic NDD with nystagmus and cone-pathway retinal dysfunction Article metadata:Article title: Biallelic loss-of-function variants in DSCAM cause a neurodevelopmental syndrome with nystagmus and retinal dysfunctionJournal: Human Genetics and Genomics AdvancesDOI: https://doi.org/10.1016/j.xhgg.2026.100622Reference: Douzgou Houge S., Bredrup C., Wivestad Jansson R., Bojovic O., Aljamal B.M., Al-Otaibi M., Plomp A.S., Motazacker M.M., van Genderen M.M., Mellgren A., Alkuraya H., Hikmat O., Haukanes B.I., Alkuraya F.S., Douzgos Houge G. Biallelic loss-of-function variants in DSCAM cause a neurodevelopmental syndrome with nystagmus and retinal dysfunction. Human Genetics and Genomics Advances 7, 100622 (July 9, 2026). https://doi.org/10.1016/j.xhgg.2026.100622. Lyrics:Verse 1I see the world in a trembling frame,A spinning ceiling, a shifting name,Signals flicker where they should align,Like broken streetlights in a neon line. Pre-ChorusTwo quiet hits in the same old code,A missing bridge on a nervous road,And the cone-lit path starts dropping out—But we trace the fault, we map the doubt. ChorusSay it plain: the wiring’s wrong, but we found the place,In the snap of the genome, in the pulse of the trace,Rods still steady while the bright steps stall,We name the pattern, we answer the call.Oh—hold on tight, we’re learning the light,We’re learning the light. Verse 2Long nights, skin electrodes, steady hands,Waveforms rising like distant bands,Bipolar sparks that should carry the dayLose their rhythm, fade to gray. BridgeNot just a stare that can’t stay still,Not just the silence in words you will,Seizures like storms in a narrow sky—But a thread that ties the “why” to the eye. Final ChorusSay it plain: the wiring’s wrong, but we found the place,In the snap of the genome, in the pulse of the trace,A small cohort, but the sign stands tall,Test the vision, let the cones talk.Oh—hold on tight, we’re learning the light,We’re learning the light.