EPISODE · May 27, 2026 · 8 MIN
乙肝有望被治愈：国产原研新药“贺普拉肽”取得重大突破
from 消化肝病前沿资讯
2026年5月，我国自主研发新药贺普拉肽在美公布Ⅱ期临床成果，部分慢性乙肝患者实现肝内cccDNA清除，触及乙肝治愈最高标准。其通过阻断病毒进入肝细胞，从源头切断cccDNA补充，联合PEG-IFN显著提升疗效，还逆转干扰素耐药，获国家科技重大专项支持，有望成全球首个实现cccDNA清除的药物，为患者带来曙光。00:06贺普拉肽公布Ⅱ期临床成果00:36解析乙肝治愈的两类标准01:53贺普拉肽阻断病毒入肝细胞02:51Ⅱ期临床试验设计详情03:40联合治疗提升病毒学应答04:32实现部分患者灭菌性治愈05:22安全性良好且降pgRNA06:20逆转干扰素耐药获国家支持07:09Ⅲ期试验将启或改写治疗范式08:06为其他病毒治疗提供新思路
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乙肝有望被治愈：国产原研新药“贺普拉肽”取得重大突破
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