Your DNA Holds the Key: Why Some Supplements Make You Worse

Today on the Holistic Dentistry Show, Dr. Sanda Moldovan speaks with Dr. Tyler Panzer, a PhD scientist with expertise in pharmacology and genetics, about how genetic testing can revolutionize our approach to supplementation and health. Dr. Panzer shares his personal journey of using genetic insights to solve his own health issues with anxiety, brain fog, and sleep problems. Dr. Panzer explains how standard genetic testing reports often miss crucial information and why truly personalized medicine requires deeper analysis. He uses vitamin D as a powerful example, demonstrating how mutations in different genes can affect our ability to produce, convert, and utilize this essential nutrient. This explains why some people remain deficient despite high supplementation or sun exposure, and why blood levels that appear "normal" may still be insufficient for cellular function. The conversation explores how common supplements like curcumin, resveratrol, and berberine can actually worsen symptoms for people with certain genetic profiles. Dr. Panzer introduces his concept of "hyper-personalized medicine," focusing on cellular needs rather than disease labels, and explains why seemingly unrelated conditions may respond to similar interventions when approached from this perspective. He shares remarkable client success stories, including cases where targeted supplements based on genetic analysis quickly resolved panic attacks and improved Alzheimer's symptoms. Want to see more of The Holistic Dentistry Show? Watch our episodes on YouTube! Do you have a mouth- or body-related question for Dr. Sanda? Send her a message on Instagram! Remember, you're not healthy until your mouth is healthy. So take care of it in the most natural way.  Key Takeaways: (00:01:24) Dr. Panzer's journey into genetics after his own health struggles (00:03:23) How genetic insights helped resolve his histamine issues (00:05:24) The problem with our current approach to genetic testing (00:08:34) Why cells need different nutrients based on genetic variations (00:09:10) The complex genetic factors affecting vitamin D utilization (00:12:41) Why standard blood test ranges may not reflect optimal levels (00:16:26) The importance of understanding pharmacology in genetic analysis (00:19:52) Common supplements that can help or harm based on genetics (00:25:44) How "health foods" can cause anxiety in certain genetic profiles (00:28:26) The "monkey on your back" feeling from the wrong supplements (00:31:15) Why genetic reports often contradict themselves (00:34:41) The bottom-up vs. top-down approach to health problems (00:37:13) Client success stories with targeted genetic interventions (00:41:32) How common foods can disrupt sleep in genetically sensitive people (00:44:13) Understanding cell signaling pathways for better health outcomes Guest Info:  Dr. Tyler Panzer Connect With Us:  AskDrSanda | YouTube BeverlyHillsDentalHealth.com | Instagram  DrSandaMoldovan.com | Instagram  Orasana.com | Instagram