Zaynich: A New Weapon Against MDR Gram-Negatives

In this episode of Diabetic Foot Files, Dr. G explores Zaynich (cefepime + ZD-bactam), a newly FDA-approved IV antibiotic designed to overcome multi-drug resistant gram-negative infections. He explains the drug's dual-target mechanism, its potential role in limb salvage for severe diabetic foot infections, common side effects, dosing, current FDA indications, and when to involve infectious disease specialists. Listeners will learn why this combination may be a game-changer for difficult-to-treat infections, the importance of antibiotic stewardship, and practical considerations for use in wound care and limb salvage scenarios.