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Jun 11, 2026 47 min

Zero Trust for AI Agents

from Practical AI Hosted by Daniel Whitenack and Chris Benson

As AI agents become more capable and autonomous, they also introduce new security challenges. In this 'Fully Connected' episode, Dan and Chris unpack Anthropic’s Zero Trust for AI Agents security framework and what it means for organizations deploying agentic systems. They examine the key security risks facing agentic systems and discuss how organizations can apply Zero Trust principles to deploy AI agents safely. Along the way, they break down practical security controls and discuss how traditional cybersecurity principles must evolve for the age of AI agents. Featuring: Chris Benson – Website, LinkedIn, Bluesky, GitHub, X Daniel Whitenack – Website, GitHub, X Links: Zero Trust for AI Agents OWASP GenAI Project Sponsors: Prediction Guard: A self-hosted AI control plane for running agents in high impact environments. predictionguard.com/practicalai Upcoming Events: Register for upcoming webinars here! Midwest AI Summit 2026

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Zero Trust for AI Agents

0:00 47:02

Chapters

  1. 0:00 Welcome to Practical AI!
  2. 1:17 Introduction to AI and Security Frameworks
  3. 3:28 Understanding Zero Trust in AI
  4. 6:32 The Rise of Autonomous Agents
  5. 9:06 Current Threat Landscape for AI Agents
  6. 12:23 Anthropic's Zero Trust Framework Overview
  7. 15:02 Identifying and Mitigating Risks
  8. 17:52 Implementing Security Measures for AI Agents
  9. 20:47 Behavioral Monitoring and Response
  10. 23:02 Sponsor: Prediction Guard
  11. 25:26 Input Validation and Output Controls
  12. 28:23 Integrity and Recovery in AI Systems
  13. 31:10 Phased Implementation of Security Measures
  14. 34:00 Conclusion and Future Considerations
  15. 46:21 See you next time!

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This episode was published on June 11, 2026.

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