Zhen Xu PHD - ULTRASOUND AND CANCER CELLS: HISTOTRIPSY EXPLAINED

How Can Ultrasound destroy cancer cells and even increase immune response elsewhere? Are there any implications for a resonant field based understanding of matter? In this episode we have the fascinating invention of Histotripsy (https://histotripsy.umich.edu/), the non-invasive destruction of cancer cells using ultrasound to look into. Alongside the other headline news that bioengineers are also using acoustics to pattern replacement heart tissue, makes the field of bioacoustics one of the most exciting for the future of medicine.  It is of course the implications of this for the resonant vibrational nature of matter that make this of interest to us on the show, as we attempt to get closer to a true understanding of the nature of reality through our shows on the implications of Einstein’s ‘matter is energy’ findings and quantum mechanics. We get into this after 45 mins or so. We are lucky enough to be speaking today with one of the inventors of Histotripsy technology, Zhen Xu, Associate Professor and Graduate Chair of the Department of Biomedical Engineering at Michigan University. She’s won many awards for her research, including from the American Heart Association and from the National Institute of Health.  00:00 Intro 07:25 Destroying Cancer Cells with Ultrasound  08:50 Issues with tissue heating and toxicity in other non-surgical techniques 09:50 Cavitation: the creation, expansion and collapse of bubbles - gas pockets in the tissue 11:40 Ultrasound propagates through the vibration of tissue particles 13:36 Acoustic Scalpel: Cavitation bubbles are highly visible on ultrasound imaging, for high accuracy treatment 14:45 No spread of tissue heating, so no healthy tissue damage 16:00 The discovery happened by mistake 19:45 She developed new devices for a new phenomenon  21:40 Toxicity of the destroyed tumour is removed from the body in a few months 24:30 Immune response to tumerous cells after treatment, possibly from the debris 25:40 Live cancer cells alter signal pathways to confuse the immunes system 28:00 But once dead the the debris can are noticed by the immune system  29:45 Future tumours or relapses in different locations are picked ups by the immune system 33:30 Treating neurological disease, brain blood clots and epilepsy too, across the skull protection 40:30 Patterning and forming new cell structures using sound (Stanford Med research): Structuring vs destructing using sound 44:30 Resonant frequency in various types of matter and biological tissue 45:00 No evidence from the lab for a resonant theory of tissue/organ health 48:50 Nikola Tesla, “If you want to find the secrets of the Universe, think in terms of energy, frequency and vibration” 52:00 The implications of a wider wave-length fields, for the creation and maintaining of matter and biological life’s structure 56:30 Bioelectric component in organ development (TUFTS Study): The formation of life depends on more than DNA 1:01:00 A field based understanding of physical matter, rather than matter generating fields   References: Dr Zhen Xu 'Histotripsy: the first noninvasive, non-ionizing, non-thermal ablation technique based on ultrasound' Paper Dr Zhen Xu - Histotripsy Group Cosmos Magazine Article on Histotripsy Dr Cliff Cho, Dr Zhen Xu - “...Immune responses that enhance cancer immunotherapy” Paper Sean Wu and Utcan Demerci, Stanford Medical School, Engineering Heart tissue using Bioacoustics Havana Syndrome Nikola Tesla quote, “If you want to find the secrets of the Universe, think in terms of energy, frequency and vibration” Micheal Levin, TUFTS university, “changes in bioelectric signals cause tadpoles to grow eyes in back and tail”