Zoe Lyons Opens Up About Relationship Breakdowns, HRT Scares & Her Midlife Crisis episode artwork

EPISODE · Apr 13, 2026 · 50 MIN

Zoe Lyons Opens Up About Relationship Breakdowns, HRT Scares & Her Midlife Crisis

from Is It Hot In Here? Midlife Podcast · host Dr Naomi Potter

Menopause or midlife crisis?🤝 Get your own personalised menopause support from Dr Naomi Potter and her team: https://www.menopausecare.co.uk/what-to-expect-ihihIn this week’s episode, Dr Naomi Potter is joined by comedian Zoe Lyons for a funny, raw and surprisingly moving conversation about what menopause can really do to your mind, confidence, work and relationships. Zoe opens up about the hot flushes that hit out of nowhere, the depression and rage that followed, and why she bought a sports car.Together, Naomi and Zoe talk about HRT, testosterone, brain fog, motivation, exercise, therapy and the strange grief of feeling like you’ve lost the version of yourself you used to know. If you’ve been feeling flat, overwhelmed, unlike yourself or tempted to run away from your life, this episode will make you feel very seen.💬 Topics include:• Menopause symptoms • Why menopause can feel like a midlife crisis• Menopause at work• Relationship strain during midlife • HRT for menopause symptoms• Menopause rage• Brain fog• Testosterone in women• Exercise and running for menopause • Body image and ageingFollow Zoe Lyons below:Zoe’s Instagram: @zoelyonscomedyListen to Zoe's running & comedy podcast The Running Joke: https://open.spotify.com/show/2Hd4lR0ynIlEcSvMRNGrPv?si=fe38e79a62744a5fFollow Dr Naomi Potter below:Naomi’s Instagram: @dr_naomipotterNaomi’s TikTok: @dr_naomipotter0:00 – Zoe Lyons on perimenopause and comedy1:29 – Zoe’s first symptoms and starting HRT2:31 – Covid, midlife crisis and everything falling apart5:56 – How therapy helped save Zoe’s relationship9:48 – Why menopause changed her confidence and work13:42 – Depression, low mood and menopause15:07 – How running helped her mental health19:06 – Zoe’s HRT journey: tablets, gel and progesterone24:20 – Brain fog, low motivation and low testosterone32:00 – Why menopause information still feels confusing33:49 – Can you stay on HRT forever?38:05 – Menopause hair loss, skin changes and aging43:10 – Is it a midlife crisis or perimenopause?45:20 – How to reconnect with your ageing body#menopause #midlifecrisis #zoelyons

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Zoe Lyons Opens Up About Relationship Breakdowns, HRT Scares & Her Midlife Crisis

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