Zombie Cells Fuel Aging Inflammation | Science News

Scientists have uncovered how “zombie” senescent cells fuel chronic inflammation in aging: their malfunctioning mitochondria overproduce acetyl-CoA, loosening DNA to activate inflammatory genes—and simultaneously leak genetic material that triggers immune responses. This dual mechanism creates a persistent low-grade fire of inflammation tied to age-related diseases. But here’s the breakthrough: blocking acetyl-CoA in mice slashed inflammation, improved tissue health, and slowed aging—even with mitochondrial damage still present. It’s a new metabolic target for fighting age-driven decline. Listen in comfort:Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Sources:https://www.sciencedaily.com/releases/2026/09/260911214301.htm More coverage & latest updates:https://sources.thednn.ai/a2c892d00bf516ce Report issues to [email protected].