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PODCAST · health

Against the Grain

by Samir Kakodkar

Host: Samir Kakodkar, MD - specialist in Crohn's disease and ulcerative colitis Medical School: Northwestern Feinberg School of Medicine Internal Medicine Residency: Rush University Medical Center Fellowship in Gastroenterology and Hepatology: Advocate Lutheran General Hospital Advanced Fellowship in Inflammatory Bowel Disease (Crohn's and Colitis): Northwestern Memorial Hospital Practice Location 7900 N Milwaukee Ave Suite 19, Niles, IL 60714 For appointments: 847-318-9595 Contact: [email protected] YouTube channel: https://www.youtube.com/channel/UCSzuuqUFGgtcwpAbtL5b0xw If interested in scheduling a phone conversation with me, please visit https://calendly.com/samir3/against-the-grain Twitter: @KakodkarSamir

Publisher-supplied feed metadata · PodParley refreshed Feb 5, 2026 · Source feed

Episodes

  1. Episode 34: My Unbiased Breakdown of Zeposia (Ozanimod) for Ulcerative Colitis

    This is my review of Zeposia (Ozanimod), a new once a day oral medication for moderate to severe ulcerative colitis. I go over the True North Study (https://www.nejm.org/doi/full/10.1056/NEJMoa2033617) in detail including efficacy and safety data. I have no conflicts of interest with any...

  2. Episode 33: What Do Your Biopsies Mean? The Pathology of Crohn's and Colitis - Shriram Jakate, MD

    Dr. Shriram Jakate is Professor Emeritus in pathology at Rush University Medical Center. He has a particular expertise in GI and liver pathology and has been interpreting slides from patients with Crohn's and colitis for over several decades. I consider him to be the best GI pathologist I have...

  3. Episode 32: It's Game Time! Management of Fistulizing Crohn's Disease

    This is a discussion with Dr. Assad Munis, third year gastroenterology fellow at Advocate Lutheran General Hospital, about his recent presentation "Initial Approach to Fistulizing Crohn's Disease" at our grand rounds. We discuss pathophysiology, diagnosis, and primarily medical management. We…

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  4. Episode 31: Start Here if you have Crohn's Disease or Ulcerative Colitis!

    I made this podcast for those who are newly diagnosed with Crohn's disease or ulcerative colitis. Dr. K’s Simplified Prescription to Treat IBD (it’s not that complicated to know what to do) 1.Start with appropriate and optimized medical therapy, preferably by an IBD specialist (like myself). 2.If...

  5. Episode 30: A Deep Dive into the DINE Study: The Specific Carbohydrate Diet vs Mediterranean Diet for Crohn's Disease

    This podcast is a deep dive into the recently published article "A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults With Crohn’s Disease." (also known as the Dine Study) published by Lewis, et al. Article link is here:...

  6. Episode 29: The IBDCoach Update and Ksharustra (Ayurvedic Seton) for Fistulizing Crohn's Disease

    This is my second podcast with IBDCoach. We try to make sense of all the IBD diets, supplements and medications out there which can be so confusing! We also have a detailed discussion regarding Andrew's use of Ksharsutra (Ayurvedic Seton) to treat his fistula. I am not officially endorsing or...

  7. Episode 28: Whole Food Plant Based Diet for Crohn's and Colitis: Shamiz and Shukul Kachwalla

    There are many reasons why a whole food plant based diet may be helpful for Crohn’s disease and ulcerative colitis. Data suggest limiting omega-6 PUFAs (ie oils), saturated fats, animal protein, and food additives may be associated with a reduced risk of developing IBD. A whole food plant based...

  8. Against the Grain Theme Song (Version #1)

    For all the mega Against the Grain fans out there, here is the full theme song, version #1 in all its glory. The part you are familiar with is in the middle of the track. Produced and Written by Samir Kakodkar. Borrowed some parts from theme from the ABC reality TV show The Mole (that nobody...

  9. Against the Grain Theme Song (Version #2)

    For all the mega Against the Grain fans out there, here is the full theme song, version #2 in all its glory. Produced and Written by Samir Kakodkar Circa 2003 at Northwestern University, Foster Walker Complex, on a microKorg and Garage Band.

  10. Does Mycobacterium Avium Paratuberculosis (MAP) Cause Crohn's Disease?

    There are many theories out there regarding what causes Crohn’s disease. Though ultimately most physicians and scientists acknowledge that we don’t know the cause, there is a small subgroup that believe Crohn’s disease is caused by a specific bacteria called mycobacterium avium paratuberculosis...

  11. Top 10 Ready to Eat Foods for Crohn's and Colitis Diets

    This is a show on some of my favorite ready-made food items. These would be considered processed foods to some degree, but definitely less processed than the types of things you would find at The Dollar Store or even a regular grocery store chain. Sometimes it’s nice to have food on hand that you...

  12. How Does Stress Affect Crohn's and Colitis? A Review of the Literature and Case Study of a Healed Colon

    This show will focus on the effect of stress on Crohn’s disease and ulcerative colitis. I will define stress as the feeling of being challenged by a threatening event or evolving situation. Everyone experiences some degree of stress in life, but when it becomes chronic and perceived as severe, it...

  13. Coronavirus in Gastroenterology, Hepatology and Inflammatory Bowel Disease

    Today we are going to tackle Coronavirus, specifically SARS-CoV-2 which causes the disease COVID 19 in relation to gastrointestinal symptoms and disease. I will be interviewing Dr Kaushal Majmudar who is one of our great GI fellows at Advocate Lutheran General Hospital. He recently did a Grand...

  14. Plant Based Diet for Crohn's and Colitis: Mitsuro Chiba, MD PhD

    Dr. Mitsuro Chiba is an MD, PhD is a gastroenterologist and researcher at Akita City Hospital, Kawamoto, Akita City, Japan. He believes that inflammatory bowel disease is a lifestyle disease mediated mainly by a westernized diet, and has had many subsequent publications detailing his use of a…

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  15. Over 50 years on the Specific Carbohydrate Diet for Ulcerative Colitis: Judy Herod, Daughter of Elaine Gottschall

    This is my much anticipated interview with Judy Herod who has been on the Specific Carbohydrate Diet (which we will often abbreviate as SCD) for over 50 years for ulcerative colitis with rapid clinical response and sustained drug-free remission. Her mother is the late Elaine Gottschall…

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  16. The IBD-AID: Anti-inflammatory Diet for Crohn's and Colitis

    Barbara Olendzki RD, MPH, LDN is Associate Professor of Medicine and the Nutrition Program Director of the Center for Applied Nutrition at the University of Massachusetts. She is passionate about research and clinical care of patients with inflammatory bowel disease (IBD), cardiac concerns…

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  17. Patient Empowerment, Precision Medicine and Next Generation Approaches in Crohn's and Colitis

    Two guests for you today! The first is Andrew Kornfeld ([email protected] | https://www.facebook.com/andrew.kornfeld.18) who holds degrees in neuroscience and psychology from UCSC and has won awards for his work in science education. He has Crohn’s disease and has been able to achieve clinical…

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  18. Understanding the Pathogenesis of Inflammatory Bowel Diseases, and moving towards a "Functional Cure": Michael Briggs, PhD

    Dr. Michael Briggs is a physicist who had ulcerative colitis which he claims to have "functionally cured" using a system he developed called The Briggs Protocol. He read every article on IBD he could get his hands on and wrote a document called "Understanding the Pathogenesis of Inflammatory…

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  19. Blue Light, EMF, Circadian Rhythm, Mitochondria and Quantum Biology for IBD: Jack Kruse, MD

    Dr. Jack Kruse is a practicing neurosurgeon and also a "theoretical quantum biologist." He specifically has an interest in our light environment, circadian rhythm and mitochondria in relation to health and disease. In my opinion, these are topics that require more attention and research in the...

  20. Ayurveda for Crohn's and Colitis: Dr. Vikram Chauhan

    Although my training is in evidence based medicine (or what other alternative fields refer to as “allopathic medicine”), I am fascinated by other disciplines that operate on a completely different understanding of the human body and disease. There is much mystery surrounding Ayurveda in the US,...

  21. Jini Patel Thompson: Listening to Your Gut and Natural Treatments for Crohn's and Colitis

    Jini Patel Thompson is an internationally recognized expert on “natural healing” for digestive diseases. She says she has healed herself from widespread Crohn's Disease and has remained in drug and surgery-free remission for over 20 years. Jini has appeared on numerous TV and radio shows…

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  22. Cannabis/Medical Marijuana for Crohn's and Colitis: Arun Swaminath, MD

    If you have Crohn’s or colitis, I bet you have encountered someone either in person or on the internet who claims to be able to control his or her disease with the use of cannabis. Or maybe you are using medical marijuana already. This may seem appealing as an alternative to medications that can...

  23. IBD, Diet and Medical Therapy -- The Middle Path: Samir Kakodkar, MD

    After 10 years of researching the Specific Carbohydrate Diet (SCD) and implementing it along with other dietary therapies clinically, I wanted to share some of the insights I've gained along the way. I present the major findings of my research studies including brand new, exciting results from…

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  24. Saffron Cassaday, Director of Designer Shit (Fecal Transplant for IBD)

    Fecal microbiota transplantation, otherwise known as FMT, is putting the stool from one person into the GI tract of another. This is an accepted treatment for recurrent clostridium dificil colitis which is a type of bacterial infection. Because we know that people with Crohn’s and colitis have a...

  25. Raman Prasad - Specific Carbohydrate Diet for 20 years

    I spoke with Raman Prasad who has been following the Specific Carbohydrate Diet for 20 years with sustained drug free remission of his colitis. He had a severe case of inflammatory bowel disease with possible primary sclerosing cholangitis and was facing surgery before discovering the SCD. He has...

  26. Healing Crohn's with Biohacking: Joshua Bradley

    Today I had the pleasure of interviewing Joshua Bradley who overcame a severe case of fistulizing Crohn’s disease using a combination of conventional methods, ketogenic diet, endurance exercise and supplements which were guided by a biohacking -- that is he used objective data from testing to…

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  27. Rapid Response to Diet for Colitis: Stephanie Colo Manning

    Today I spoke with Stephanie Colo Manning who is chef and owner of Colo Kitchen which offers consulting and cooking lessons for people who want to transition to a nutrient dense, whole foods diet. She also had colitis and is someone who had a relatively rapid response to the Specific Carbohydrate...

  28. Can Baking Soda Treat Crohn's and Colitis?

    The answer is we don’t know yet but there may be a mechanism to explain how it theoretically could be anti-inflammatory and possibly helpful for autoimmune disease. Today I spoke with Dr. Paul O’Connor who recently published some very interesting work on anti-inflammatory effects of baking soda…

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  29. The Man Who Treated His Crohn's By Fasting For 38 days

    Fasting is becoming more and more popular nowadays and is being promoted for everything from obesity, diabetes, cancer and now diseases of immune dysregulation. There are many forms including prolonged water fasts, fasting mimicking diets, intermittent fasting and time restricted eating. There is...

  30. Hyperbaric Oxygen Therapy for IBD: Dr. Scott Sherr

    Today we are talking about hyperbaric oxygen therapy for inflammatory bowel disease. This is a hot topic with some studies suggesting efficacy in both Crohn’s disease and ulcerative colitis. Recently there has been interest in using it for hospitalized patients with severe ulcerative colitis. We...

  31. Garin Aglietti: Gut Ecology, Worm Therapy and Fecal Microbiota Transplants for IBD

    Garin Aglietti is a worm farmer and gut ecology expert who offers worm therapy and fecal transplants for patients with autoimmune diseases including Crohn's disease and ulcerative colitis. These treatments are not currently offered as standard of care options for the vast majority of IBD patients...

  32. Wanted: Crohn's End

    We venture into the realm of complementary and alternative medicine(AKA CAM) for Crohn’s and ulcerative colitis. These include various diets, supplements, and other lifestyle interventions that are not part of the standard of care. Today we speak to Reid Kimball who has made a documentary called...

  33. When Nothing Works, Surgery Can (Part 2)

    We catch up with a patient who recently had surgery for severe ulcerative colitis. We talk about his experience and his decision regarding if he should get a J pouch. We also address prior criticisms about how we discussed the Specific Carbohydrate Diet on the prior podcast.

  34. When Nothing Works

    A conversation with a friend with ulcerative colitis (possibly Crohn's colitis) who is now facing surgery. He tried his best to avoid it including implementing some very unconventional things - diet, fecal transplant, a medication called Xeljanz (prior to FDA approval) and even hyperbaric oxygen...

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ABOUT THIS SHOW

Host: Samir Kakodkar, MD - specialist in Crohn's disease and ulcerative colitis Medical School: Northwestern Feinberg School of Medicine Internal Medicine Residency: Rush University Medical Center Fellowship in Gastroenterology and Hepatology: Advocate Lutheran General Hospital Advanced Fellowship in Inflammatory Bowel Disease (Crohn's and Colitis): Northwestern Memorial Hospital Practice Location 7900 N Milwaukee Ave Suite 19, Niles, IL 60714 For appointments: 847-318-9595 Contact: [email protected] YouTube channel: https://www.youtube.com/channel/UCSzuuqUFGgtcwpAbtL5b0xw If interested in scheduling a phone conversation with me, please visit https://calendly.com/samir3/against-the-grain Twitter: @KakodkarSamir

HOSTED BY

Samir Kakodkar

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Frequently Asked Questions

How many episodes does Against the Grain have?

Against the Grain currently has 35 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.

What is Against the Grain about?

Host: Samir Kakodkar, MD - specialist in Crohn's disease and ulcerative colitis Medical School: Northwestern Feinberg School of Medicine Internal Medicine Residency: Rush University Medical Center Fellowship in Gastroenterology and Hepatology: Advocate Lutheran General Hospital Advanced Fellowship...

How often does Against the Grain release new episodes?

Against the Grain has 35 episodes. Check the episode list to see recent publication dates and frequency.

Where can I listen to Against the Grain?

You can listen to Against the Grain on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.

Who hosts Against the Grain?

Against the Grain is created and hosted by Samir Kakodkar.
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