PODCAST · health
ANA Investigates
by American Neurological Association
At a time when support for basic and translational science needs a strong voice and the burden of neurological disease is growing, the ANA is the champion of neurological research and the ally of all physicians and scientists who strive to make a difference through careers that combine discovery, education, and clinical care.From advances in stroke and dementia to movement disorders and epilepsy, the American Neurological Association has been at the forefront of research and practice since 1875 as the premier professional society of academic neurologists and neuroscientists devoted to understanding and treating diseases of the nervous system.
Episodes
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ANA Investigates the Making of Women Leaders in Academic Neurology
Women are reshaping leadership in academic neurology, representing a growing share of the field yet remaining underrepresented in its most senior roles. In this episode of ANA Investigates, we had the privilege of speaking with two former women presidents of the American Neurological Association....
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ANA investigates Mechanical Thrombectomy for Medium Vessel Occlusions
In this episode, we are discussing one of the most rapidly evolving areas in acute stroke care, mechanical thrombectomy for medium vessel occlusions, or MEVO. While thrombectomy is well established for large vessel occlusions, whether patients with smaller, more distal occlusions benefit has...
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ANA Investigates Pediatric Epilepsy Surgeries
In this episode, we'll discuss pediatric epilepsy surgery. Pediatric epilepsy surgery has undergone a remarkable evolution, moving from a treatment of last resort to a critical option for children with drug-resistant epilepsies. Yet major barriers remain, including delayed referrals, fear of…
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ANA investigates ALS Research and Healey ALS MyMatch
In this episode, we will focus on the latest in the research on ALS. ALS remains a devastating disease, but the field is now at an inflection point with a growing pipeline of precision therapies, trial-ready sites, and a new generation of clinician scientists - yet barriers persist. There is...
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ANA investigates the Evolution of the ANA Podcast
ANA Investigates is the official podcast of the American Neurological Association, featuring conversations that highlight the latest discoveries, controversies, and trends in academic neurology. After the successful release of over 80 podcast episodes, In today's episode, we'll explore the…
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ANA Investigates Debates in Idiopathic Normal Pressure Hydrocephalus
The diagnosis and management of idiopathic normal pressure hydrocephalus (NPH) is evolving. However, skepticism about this diagnosis persists among neurologists based upon lack of disease specific pathology, overlap with other neurodegenerative processes, and a lack of uniform diagnostic…
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ANA Investigates Adaptive DBS
Last year, the FDA approved adaptive deep brain stimulation for the treatment of people with Parkinson's disease. This is a major step forward in neurology. It allows personalized therapy by adjusting deep brain stimulation settings in real-time based on an individual's brain signals. Our guest…
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ANA investigates NORSE and FIRES
In this episode, we'll focus on new onset refractory status epilepticus or NORSE, and its closely related presentation, febrile and infection related epilepsy syndrome, known as FIRES. NORSE and FIRES are clinical presentations where the evidence is limited, stakes are high, and treatment often…
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ANA Investigates Emerging Strategies to Enhance Stroke Recovery
In this episode, we'll explore emerging strategies to enhance recovery after stroke. Stroke rehabilitation has long relied on physical, occupational, and speech therapy, but advances in neuroscience are opening new opportunities to directly modulate brain networks, promote plasticity, and…
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ANA Investigates Stroke and its Future: Reflections of a Legend
Today, we'll talk with one of the true giants of stroke neurology - Dr. Louis Caplan, Professor of Neurology at Harvard Medical School and Senior Neurologist at Beth Israel Deaconess Medical Center. For decades, Dr. Caplan has shaped how we think about stroke. He's authored an enormous body of…
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ANA Investigates AI for Clinical Care
This is episode, we'll look at a national effort to advance clinical research and patient care through artificial intelligence. AI depends on data that are large, diverse, and well-labeled -- in contrast, most clinical data are siloed, inconsistent, and biased toward certain populations. The…
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ANA Investigates ANA2025
The American Neurological Association's 150th Annual Meeting held in Baltimore September 13-16, 2025 was a milestone meeting celebrating 150 years of progress, discovery, advances in science, and the remarkable work of academic neurologists and neuroscientists over the past century and a half.…
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ANA Investigates: 75 Years of NINDS
Tune into the latest podcast from the American Neurological Association (ANA), ANA Investigates: 75 Years of NINDS. This year marks the 75th anniversary of the National Institute of Neurological Disorders and Stroke (NINDS)—an opportunity to reflect on the institute's past achievements and look...
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New and Emerging Therapies for Myasthenia Gravis
Today we'll focus on a major shift in the treatment of myasthenia gravis -- as a wave of new therapies is changing how we treat this disease. Who should be considered for these new treatments? And what else is in the pipeline? Our guest today is Dr. Gil Wolfe, a neuromuscular neurologist at the...
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ANA Investigates Vector-Borne Illness
Climate change is no longer a distant worry—it's showing up in neurology clinics across the US, from Lyme meningitis in the Midwest to worsening migraines during heat waves, climate-linked and vector-borne neurological conditions are entering the differential. Our guests today are two experts on...
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ANA Investigates RLS
Restless leg syndrome is a common movement and sleep disorder affecting 2-3% of the population. Certain neurologic disorders are associated with a higher incidence, and neuropsychiatric medications prescribed by neurologists and psychiatrists often exacerbate these symptoms. In January, the...
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ANA Investigates The Neural Exposome
Look around you right now and think for a minute about all of the things you're exposed to: the coffee you're drinking, the mug holding the coffee you're drinking, the soap that mug was washed in, the sleep you got last night -- or didn't get. All of this is part of what we now call your…
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ANA Investigates Health Policy and Advocacy in Neurology
Neurologists bring an important perspective to health policy. But few have formal training in how to advocate for patients at a state or national level. Our guest today, Dr. Kara Stavros, is an associate professor of neurology at The Warren Alpert Medical School of Brown University and the...
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ANA Investigates Biological Staging of Parkinson's Disease
Parkinson's Disease has long been a clinical diagnosis. But recently, there have been proposals to redefine the disease based on biomarkers of alpha-synucleinopathy and dopaminergic dysfunction. A similar shift has already occurred in Alzheimer disease, with the "amyloid, tau, and...
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ANA Investigates Atrial Fibrillation After Stroke
We all know that atrial fibrillation is associated with increased risk of stroke. But new research suggests that how we define afib -- and the timing and duration of the arrhythmia -- may be important for how we manage it in stroke patients. Luciano Sposato is a Professor of Neurology and Head of...
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ANA Investigates Dementia in Africa
Dementia is a global issue, with two-thirds of people with dementia living in low- and middle- income countries. Despite this, dementia research continues to focus on patients in high-income countries. Our guest on this episode, Dr. Riadh Gouider, is working to correct this imbalance. Dr. Gouider...
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ANA Investigates Minimally Invasive Surgical Treatments in Epilepsy
It used to be that surgery for medically refractory epilepsy was big, open and invasive, a treatment of last resort. The landscape has changed in recent decades, with more and more minimally invasive surgical approaches being developed. So what does this mean for the average patient with…
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ANA Investigates the Glymphatic System & Neurodegenerative Diseases
Until recently, the Glymphatic System was a neglected corner of neuroscience. Now it's increasingly clear that the brain's system for the flow of fluid, nutrients, and waste plays an important role in sleep and brain disease. With glymphatics in the spotlight, researchers are coming up with...
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**Bonus Episode** ANA Investigates ANA2024
Just last week, we wrapped up another exciting annual meeting of the American Neurological Association, ANA2024. Right before we packed up to head home, the President of the American Neurological Association, Dr. Betsy Ross, sat down with Dr. Allison Willis, the 2024 chair of the ANA's Annual...
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ANA Investigates Psychedelics & Unlocking Critical Periods
Listen as Dr. Adeline Goss, Associate Chief of Neurology at Highland Hospital, discusses the groundbreaking potential of psychedelics in neurology with Dr. Steve Zeiler, a Vascular Neurologist and Associate Professor at Johns Hopkins, and Dr. Ghul Dölen, a Professor of Psychology and Neuroscience...
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ANA Investigates AI in Academia
AI is everywhere, whether you are a fan of it or not. This month, join us for a deep dive into the AI revolution with our guest Dr. Ethan Mollick, professor at The Wharton School at the University of Pennsylvania and author of the New York Times bestseller, "Co-Intelligence." Discover how this AI...
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ANA Investigates Minimally Invasive Neurosurgeries for Spontaneous Intracerebral Hemorrhage
There has been tremendous progress in recent decades in the management of ischemic strokes. Meanwhile, hemorrhagic strokes have stubbornly resisted this progress. Interventions for these types of strokes have failed again and again to show a benefit over standard medical management, until this...
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ANA Investigates MMA Embolization
2024 has been a year of exciting trials on minimally invasive techniques in intracranial hemorrhage. This month we're focusing on Chronic Subdural Hematoma, where a minimally invasive strategy called Middle Meningeal Artery (MMA) Embolization is offering expanded treatment options for select...
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ANA Investigates Neuroprognostication After Cardiac Arrest: Nihilism vs. Over Optimism
Football fans may remember in January 2023 when Damar Hamlin, a player for the Buffalo Bills, suffered a cardiac arrest and collapsed on the field during a game on live television. He had a remarkable neurologic recovery, prompting us to focus our podcast that month on the need to avoid nihilism...
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ANA Investigates Advanced Therapies for Glioblastoma
Glioblastoma is the most common malignant brain tumor and one of the most aggressive solid tumors. Much progress has been made in the understanding and classification of gliomas, but progress in terms of prolonging survival has been limited. Several recent investigational therapies are bringing…
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ANA Investigates Updated Brain Death Determination Guidelines
Brain death is one of the most controversial and ethically complex topics in neurology, but it's a regular part of our clinical practice. Late last year, a new set of guidelines was published that address some of the thorniest technical and ethical issues in the clinical determination of brain...
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ANA Investigates Auto-Antibodies for Small Fiber Neuropathy
Small fiber neuropathy is one of those conditions in neurology that can feel frustratingly intangible. Even for patients with severe neuropathic pain and autonomic symptoms, in about half of cases, the usual lab testing doesn't reveal a cause. There's increasing evidence that autoimmunity may be…
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ANA Investigates the Clinical Implementation of Lecanemab for Alzheimer's Dementia
The recent FDA approval of lecanemab, an amyloid-sequestering agent, has been hailed as a breakthrough in the treatment of Alzheimer disease. Critics of the drug have pointed to its cost, risks, and treatment burden. Now that lecanemab is being administered in clinics across the country - how is…
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ANA Investigates Chronic Pain
Chronic pain can be incredibly challenging -- for patients, of course, and also for their physicians. On this episode of ANA investigates, Dr. Adeline Goss talks to Dr. Prasad Shirvalkar of UCSF about a new possible strategy for treating chronic pain: deep brain stimulation. Series 5, Episode 2...
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ANA Investigates The Neurovasculome
The brain and its vasculature used to be considered separate domains. But in the last decade, we've learned more about the interplay between brain cells and vascular cells. Pathological studies are revealing a surprising degree of overlap between cerebrovascular disease and neurodegenerative...
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*Bonus Episode* ANA Investigates ANA2023!
As the ANA's 2023 Annual Meeting comes to a close, we wanted to catch up with Frances Jensen Chair of the Department of Neurology at University of Pennsylvania and outgoing President of the ANA, and Rebecca Gottesman, Stroke Branch Chief of the National Institute of Neurological Disorders and...
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ANA Investigates Insomnia and Stroke
A growing body of research suggests that people with insomnia are at higher risk of stroke. Listen today as we dive into how sleep health, stroke, and the nervous system all have an affect on each other. Series 4, Episode 11 Featuring: Guest: Dr. .Sonja Schuetz, University of Michigan…
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ANA Investigates Fetal Therapy
Lysosomal storage diseases are progressive, inherited disorders of metabolism, many with devastating effects on the nervous system. Some of these diseases, like Infantile-Onset Pompe disease, can be treated to some degree in childhood by giving back the missing enzyme - a strategy called enzyme...
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ANA Investigates Parkinsons and Environmental Toxins
A recent study in JAMA Neurology found an association between contaminated water at a military base in the 1970s-80s and the risk of Parkinson's disease in military service members. What do we know about Parkinson's and environmental toxins? Series 4, Episode 9 Featuring: Guest: Dr. Ray Dorsey,...
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ANA Investigates Gut-Brain Axis
There are trillions of bacteria living inside each of our gastrointestinal tracts and there's growing evidence that those bacteria communicate with the brain. Some researchers are even hopeful that drugs targeted at the gut microbiome could help treat diseases as diverse as Parkinson's disease,...
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ANA Investigates Disruptive Technologies: The Future of Neurotechnology
Recently on the podcast we've been talking about neurotechnology -- devices that interface with the brain to treat disease, for example by restoring speech function in people with locked-in syndrome, or motor function in people with paralyzed limbs. But listen to the media, and you'll also hear...
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ANA Investigates Thrombectomy in Patients with Large Ischemic Strokes
Among several highlights of the recent International Stroke Conference was new evidence supporting endovascular thrombectomy for patients with so-called "large core" ischemic strokes. In current practice, thrombectomy is considered for patients with occlusions of the internal carotid or middle...
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ANA Investigates TBI and Sports Medicine
Concussion, or mild acute traumatic brain injury, is incredibly common -- 1 in 5 of adolescents report having suffered a concussion at some point in their lifetime (JAMA. 2021;325(17):1789-1791)... and an estimated 1 in 5 players of contact sports suffer a concussion each season. Sports...
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ANA Investigates Neuroethics and Disruptive Technologies Part 2: You Read My Mind
On our December show, we talked about ethical issues surrounding brain-computer interfaces. We'll pick up the topic again this month with a discussion about one type of brain-computer interface: neuroprosthetics. Our guest is Dr. Edward Chang, Professor and Chair of Neurological Surgery at the...
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ANA Investigates the Brain and CPR: Paths to Recovery
Football audiences were shaken on January 2nd when Buffalo Bills safety Damar Hamlin suffered a cardiac arrest after a tackle during a Monday Night Football game. He was resuscitated on the field and then transferred to the University of Cincinnati Medical Center in critical condition. Thus began…
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ANA Investigates Myalgic Encephalomyelitis in the Age of Long COVID
The emergence of the syndrome known as long COVID has brought new attention to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). In this episode, we explore the advances in science that may soon lead to answers. Series 4, Episode 2. Featuring: Guests: Drs. Sonya Marshall-Gradisnik &...
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ANA Investigates Disruptive Technologies: Neuroethics Role in Advancing Innovation
Neurotechnology like DBS or transcranial magnetic stimulation have clear benefits in diagnosis and therapy and are largely embraced by the medical community. But what about recent accelerated development from tech entrepreneurs to harness cognitive pathways for everyday tasks? This is referred to...
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ANA Investigates Genetics in Epilepsies
The role of genetics in both pediatric and adult epilepsies is expanding. Now, making a genetic diagnosis in epilepsy isn't just important for family planning and prognostication - these diagnoses can also improve patients' care starting at the moment of diagnosis. Our guest today, Ingrid…
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ANA Investigates Teleneurology and Healthcare Equity
Equitable tele-neurologic care starts with first identifying disparities, then identifying how to overcome them – learn about both with Dr. Lee Schwamm on the latest ANA Investigates. Series 3, Episode 11. Featuring: Guest: Dr. Lee Schwamm, C Miller Fisher Endowed Chair in Vascular Neurology and...
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*Special Episode* ANA Investigates Potential Fabrication in AD Research Images
Late last month, the journal Science published an investigative report that accused a much-cited publication in Alzheimer's disease... of fabricating scientific images. The study under scrutiny was published in Nature in 2006 by Sylvain Lesné and colleagues. It claimed that an amyloid oligomer...
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ABOUT THIS SHOW
At a time when support for basic and translational science needs a strong voice and the burden of neurological disease is growing, the ANA is the champion of neurological research and the ally of all physicians and scientists who strive to make a difference through careers that combine discovery, education, and clinical care.From advances in stroke and dementia to movement disorders and epilepsy, the American Neurological Association has been at the forefront of research and practice since 1875 as the premier professional society of academic neurologists and neuroscientists devoted to understanding and treating diseases of the nervous system.
HOSTED BY
American Neurological Association
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Frequently Asked Questions
How many episodes does ANA Investigates have?
ANA Investigates currently has 85 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is ANA Investigates about?
At a time when support for basic and translational science needs a strong voice and the burden of neurological disease is growing, the ANA is the champion of neurological research and the ally of all physicians and scientists who strive to make a difference through careers that combine discovery,...
How often does ANA Investigates release new episodes?
ANA Investigates has 85 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to ANA Investigates?
You can listen to ANA Investigates on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts ANA Investigates?
ANA Investigates is created and hosted by American Neurological Association.
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