PODCAST · science
Axial Podcast
by Joshua Elkington
Conversations with great founders and inventors in life sciences.Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio and Seranova Bio often when they are no more than an idea. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company. We are excited to be in business with you - email us at [email protected] our newsletter: https://axial.substack.com/
Episodes
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Modern Computational Tools for Chemistry with Corin Wagen
Corin Wagen is the Founder and CEO of Rowan. During our conversation, we talk about Corin's journey from the Jacobsen Lab at Harvard to starting Rowan with his brother. Rowan builds design and simulation software for chemistry. The company uses machine learning on quantum mechanics data to…
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Evolutionary Intelligence and Biologics Discovery with Jeremy Agresti
Jeremy Agresti is the Founder and CTO of Triplebar Bio.
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AI Workflows for Biopharma with Alex Telford
Alex Telford is the Co-Founder and CEO of Convoke.
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AI Legal Software with Scott Stevenson
Scott Stevenson is the Co-Founder and CEO of Spellbook.
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Scaling Proteomics with Milad Dagher
Milad Dagher is the Co-Founder and CEO of Nomic Bio.
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Proteomics and AI with Peter Cimermančič
Peter Cimermančič is the Co-Founder and CEO of Tesorai.
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Computational Protein Design with Costas Maranas
Costas Maranas is a Professor of Chemical Engineering at Penn State.
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Patents, AI, and Business Intelligence Software with Simeon Graupe
Simeon Graupe is the Co-Founder and CEO of PatentPlus.
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R&D Partnering with Kevin Leland
Kevin Leland is the Founder and CEO of Halo Science.
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Analysis of Clinical Trials with Spencer Hey
Spencer Hey is the Co-Founder and Chief Scientific Officer of Prism Analytic Technologies.
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Deploying AI Models with Ronan McGovern
Ronan McGovern is the Founder of Trelis.
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Software Native Biotech with Bogdan Knezevic
Bogdan Knezevic is the Co-Founder and CEO of Kaleidoscope Bio.
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New Research Tools with Ryan Du and Vineeth Sendilraj
Ryan Du and Vineeth Sendilraj are the founders of Yuno.
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Precision Medicine in Surgery with Julien Hedou
Julien Hedou is the Co-Founder and CEO of Surge.
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Protein Design with Geometric Deep Learning with Karolis Martinkus
Karolis Martinkus is a senior scientist at Prescient Design, the machine learning arm of Genentech.
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Directed Evolution of Antibodies with Doug Chapnick
Doug Chapnick is the Co-Founder and CEO of BioLoomics. A platform company using directed evolution to discover antibody therapeutics. Combining cell line engineering, machine learning, and imaging. At the core of BioLoomics' technology is directed evolution, a process that mimics natural…
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Building the Ultimate Patent Assistant with Evan Zimmerman
Evan Zimmerman is the Co-Founder and CEO of Edge, that helps patent attorneys, patent agents, and inventors make the patent process less painful and more effective. He earned a Juris Doctor (JD) degree from the UC Berkeley Law School, where he specialized in IP law. Seeing the potential of AI to...
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Improving Software Engineering in Biostatistics with Daniel Sabanés Bové
Daniel Sabanés Bové is a senior principal data scientist at Roche. In our conversation, we discuss the need for better software in biotech and his career in data science. Daniel studied statistics at Ludwig Maximilian University of Munich in Germany, earning his PhD in 2013 from the University…
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Transforming biomanufacturing using software with Martin Permin
Excited to have a conversation with Martin Permin, Founder and CEO of Invert. The company is on a mission to transform biomanufacturing through advanced software and data analytics. We discuss the founding of Invert, what capabilities they give their customers, and the importance of...
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Let the Best Drug Win with Errik Anderson
Errik Anderson is the CEO and Founder of Alloy Therapeutics. Founded in 2017, the company democratizes access to drug discovery platforms and services. In our conversation, we discuss Alloy's product offering and story. Alloy has rapidly grown into a thriving ecosystem empowering the global...
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Leadership and Bioengineering with Omar Ali
Omar Ali is the Senior Director of Research at Lyell Immunopharma. Omar discusses leadership lessons he's picked up across 2 decades working at the intersection of bioengineering and drug development. Starting his first company during grad school at Harvard. Afterwards spending ~7 years at the…
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Synthetic Biology and Rapid Evolution with Chang Liu
Chang Liu is a professor at UC Irvine pioneering the application of rapid evolution in synthetic biology and protein engineering. We discuss his career and what it takes to startup & lead a new academic lab. Chang's work spans the fields of genetic engineering, synthetic biology, chemical…
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Founding Unlearn and Revolutionizing Clinical Trials with Charles Fisher
Charles Fisher is the Founder and CEO of Unlearn, that creates digital twins with AI to enable more efficient clinical trials. Founded in 2017, Unlearn started as a generative AI company looking for a problem, ending up on clinical trials & transforming how they are run. A digital Twin is a...
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Imaging Dyes and Microscopy with Luke Lavis
Luke Lavis is a senior group leader and head of molecular tools and imaging at HHMI’s Janelia Research Campus. Luke Lavis works at the interface of chemistry and biology, developing small-molecule fluorescent dyes to illuminate biological samples. Lavis and his team use modern organic chemistry…
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Autonomous Microscopy with Kevin Dean
Kevin Dean is a professor at UT Southwestern pioneering autonomous microscopes and applying them to study rare biological events, mainly metastatic colonization. In our conversation we talk about his research and the current status of microscopy. Kevin was raised in a small town in Northern...
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Biotech Company Building, Partnering, Investing Towards Better Medicines with Vikas Goyal
Vikas Goyal has one of the best records in biotech having spent over 8 years at SR One partnering with companies like Nimbus and Morphic Therapeutic before joining Pandion Therapeutics (acquired by Merck) full-time after investing in it as well. Now starting Trekk Venture Parners, Vikas' story...
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Founding Hoxton Farms and Creating the Future of Food with Max Jamilly
Max Jamilly is the Co-Founder and CEO of Hoxton Farms, a London-based startup develop cultivated fat as an ingredient for the meat alternatives industry. We discuss his journey from scientist to founder starting at Oxford where Max earned his PhD in synthetic biology. Along with his work at...
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Founding Y-Trap and Protein Engineering with Rishi Bedi
Rishi Bedi is the Co-Founder and CEO of Y-Trap a biotech company developing multifunctional fusion proteins for cancer immunotherapy. We discuss the founding story of Y-Trap, the current status of protein engineering and computational biology, along with his career leading up to Y-Trap. Rishi's...
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Founding AgBiome with Eric Ward
Eric Ward is the Co-Founder and Co-CEO of AgBiome, an agtech company that analyzes crop microbiomes to develop crop protection products & traits. Founded in 2012, AgBiome has no managers; rather, the company uses committees of employees to handle core functions like business development and...
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Chemistry to Build New Imaging Tools & Probe the Brain with Anand Muthusamy
Anand Muthusamy is a graduate student at Caltech working in the Lester Lab at the intersection of chemistry and neuroscience. In our conversation we discuss his journey starting at Penn where he studied biochemistry with a strong grounding in philosophy. Working in the Petersson lab, focused on...
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Proteomics and Deep Learning with Melih Yilmaz
Melih Yilmaz is a PhD student at the University of Washington. Where he focuses on computational biology and develop machine learning tools. Advised by William Noble and Sewoong Oh, Melih's current research interests are around proteomics, particularly building deep learning methods to analyze…
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How Our Microbiomes affect Nutrition & Pharmacology with Peter Turnbaugh
Peter Turnbaugh is a professor at UCSF studying the human microbiome’s effect on pharmacology and nutrition. In our conversation, we discuss his journey to become a scientist and help pioneer the microbiome field starting in graduate school. We talk about his research as a fellow at Harvard then...
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Founding Infinimmune & Developing Breakthrough Tools for Antibody Discovery with Wyatt McDonnell
In our conversation with Wyatt McDonnell, the Co-Founder and CEO of Infinimmune, we discuss his journey to 10X Genomics, his work there, and the founding of Infinimmune. Wyatt is a world-class inventor & immunologist working across a wide range of projects at 10X from launching BEAM...
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Becoming a World-Class Scientist & The Rules of Enzymes with Margaux Pinney
Margaux Pinney is a Sandler Fellow at UCSF and in our conversation we discuss her journey to become a scientist & leader in her field and her work around enzyme evolution. The Pinney Lab studies how enzymes work, how they got there, and how they will adapt in the future. Margaux grew up in a…
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Catalyzing Drug Discovery with AI and Scaled Chemical Libraries with Devon Cayer
Excited to put out a conversation with Devon Cayer, Co-Founder and CEO of 1859, a platform biotech company merging pico-scale screening and AI to scale small molecule discovery. We talk about his story that led him to founding 1859, how the company was built, and the long-term vision. Devon...
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Building a SaaS Company in Biotech with Abhishek Jha
In our conversation with Abhishek Jha, Co-Founder and CEO of Elucidata, we talk about what it takes to build a SaaS company in biotech, the impact of AI on life sciences, & the prerequisites to build a startup. Abhishek and I discuss his journey as an academic scientist to Agios Pharmaceuticals…
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Chemistry to Control Biology & Building a World-Class Lab with Bryan Dickinson
In our conversation, Bryan discusses everything from directed evolution and drugging RNA to what it takes to start a lab. The Dickinson Lab at the University of Chicago is a unique group composed of biochemists & synthetic chemists to cell biologists & synthetic biologists. The lab set up shop in...
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Immunometabolism, Inflammation and Chemistry Intersecting with Greg Timblin
Greg is currently a postdoctoral fellow at UCSF studying macrophage immunometabolism in cancer and infection. What makes him truly unique is his ability to do groundbreaking research while training to qualify for the Olympic Trials marathon. Although Greg didn’t make it to the Trials due to…
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Image-Activated Cell Sorting with Keisuke Goda
Keisuke Goda has set the standard for sorting cells based on images. As a professor at the University of Tokyo leading a lab of 53 scientists, Keisuke is developing new tools to explore biology at different scales. During grad school at MIT, he studied gravitational waves in the LIGO group where…
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NK Cells and Curing Cancer with Nina Horowitz
Nina is one of the up-and-coming superstars in biotech. Having just earned her PhD in bioengineering at Stanford in the Sunwoo Lab this summer, she has the scientific horsepower and storytelling ability to make a large impact on drug development, business, and the lives of patients. At the age of...
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Graph Machine Learning and Life Sciences with Hannes Stärk
Hannes is a graduate student at MIT working towards a PhD in computer science. Within the span of a few months, he has been able to publish two ICML papers: one focused on molecular property prediction and the other developing a model, called EquiBind, for drug binding prediction. Hannes, advised...
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A Common Language for Therapeutic Synthetic Biology with Justin Farlow
We talk with Justin Farlow, Co-Founder and CTO of Serotiny about his journey from UCSF to founding a company with his brother, Colin. In this conversation, Justin discusses his initial discovery of engineer-able biology from a physics lens to earning his PhD at UCSF under Zev Gartner while being…
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Extrachromosomal DNA and Cancer Development with King Hung
King is currently a graduate student in the Howard Chang Lab at Stanford. In this conversation, we discuss everything from the beginning of his scientific career to extrachromosomal DNA (ecDNA) and cancer drug development. King went to college at the University of Washington where he became...
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High-Throughput Chemistry and Engineering with Kadi Saar
Really excited to put out this conversation with Kadi Saar, an outstanding inventor and world-class computational chemist, where we discuss her career spanning childhood interests to graduate research to her work now around high-throughput structural biology and condensates. Kadi is a rising star...
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Machine Learning-Assisted Directed Evolution with Bruce Wittmann
We discuss Bruce's career from being pre-med and getting into research while at Washington University in St. Louis to working at Intrexon and going to grad school at Caltech afterwards. While at Intrexon, he saw the need for better tools to scale biology and decided to go to Caltech to pursue his...
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New Models, Tools, and Targets for the Brain: Breakthroughs in Phosphoproteomics and Neurodegeneration with Nader Morshed from the White and Tsai Labs at MIT
We discuss Nader's career from learning structural biology in the Marqusee and Alber Labs at UC Berkeley to his pioneering graduate work at MIT with Forest White and Li-Huei Tsai and now at Stevens at Harvard Medical School. The conversation is centered around the 2 groundbreaking papers he...
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Precision-First Therapeutics: Building the Next Roche with Diego Rey, Co-Founder and CSO of Endpoint Health
We discuss Diego's career from building GeneWeave (acquired by Roche) to Endpoint Health now. Endpoint is pioneering a new business model merging diagnostics, data, and drug development to start with patient data and back into a therapy. The company is using their platform to develop first-line...
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From Paint to Biotech: Turning Biology into a Predictive Science, The Story of Seven Bridges, Totient, and AbSci with James Sietstra and Deniz Kural
We discuss James' and Deniz's careers from how they first met to founding Seven Bridges and Totient and now building AbSci after Totient was recently acquired. With experience leading teams in the 100s spanning genomics and SaaS to drug development and even paint from James' childhood...
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Data Driving Experimentation: Merging Biology and Data Science with Jacob Oppenheim, VP of Integrative Data Sciences at EQRx
We discuss Jacob's career going from physics to biology and making the transition from academia to industry. Building and leading data science teams at GNS Healthcare, Indigo, and now EQRx, Jacob is one of the best data scientists in biotech. In our conversation, we talk about ways to generate...
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Next-Generation Biotech Platforms: Engineering Biology with Brian Naughton, Founding Scientist at 23andMe and Co-Founder and Head of Data at Hexagon Bio
We discuss Brian's career starting at Trinity in Dublin to Stanford, 23andMe, and Hexagon. In our conversation, we talk about the interplay between computation and biology, business models in biotech, and what it takes to build world-class teams. Brian really has the superpower of building and...
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ABOUT THIS SHOW
Conversations with great founders and inventors in life sciences.Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio and Seranova Bio often when they are no more than an idea. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company. We are excited to be in business with you - email us at [email protected] our newsletter: https://axial.substack.com/
HOSTED BY
Joshua Elkington
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Frequently Asked Questions
How many episodes does Axial Podcast have?
Axial Podcast currently has 53 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is Axial Podcast about?
Conversations with great founders and inventors in life sciences.Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio and Seranova Bio often when they are no more than an idea. If you or someone you know has a great idea or company in...
How often does Axial Podcast release new episodes?
Axial Podcast has 53 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to Axial Podcast?
You can listen to Axial Podcast on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts Axial Podcast?
Axial Podcast is created and hosted by Joshua Elkington.
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