Biologic Therapy In Rheumatoid Arthritis

Episodes

1. 6

   Episode 6: Individualizing Therapy: Today’s Options, Tomorrow’s Opportunities

   This sixth podcast program, Individualizing Therapy: Today’s Options, Tomorrow’s Opportunities, features an interview with Professor McInnes. He discusses the current state of knowledge in rheumatoid arthritis and directions for discovery in coming years.

   Mar 6, 2009

   19 min
2. 5

   Episode 5: Progress and Prognosis: Evaluating Patients' Responses to Biologic Therapy

   This fifth podcast titled Progress and Prognosis: Evaluating Patients’ Responses to Biologic Therapy features a telephone interview with Professor Schett. He discusses differences among the anti-TNF agents in the treatment of rheumatoid arthritis.

   Feb 6, 2009

   16 min
3. 4

   Episode 4: Individualizing Treatment in Rheumatoid Arthritis: The Crucial Impact of Patient Heterogeneity

   Professor VonVollenhoven discusses factors which distinguish individual responses by patients with rheumatoid arthritis to various anti-TNF agents. He describes observations of radiologic and clinical progression of illness in subgroups of patients and provides an overview of considerations in...

   Dec 5, 2008

   14 min
4. 3

   Episode 3: Anti-TNF Treatment: Focus on early Rheumatoid Arthritis. Featuring an interview with Professor Paul Emery

   Contemporary research shows that the early diagnosis and treatment of RA can offer patients the possibility of achieving remission. The goal for any patient with early RA should be to achieve remission. If a patient does not already have joint damage, the goal should be a normal acute-phase...

   Oct 3, 2008

   14 min
5. 2

   Episode 2: Establishing the Evidence: Clinical Trials with TNF Inhibitors

   Professor Smolen discusses the evidence supporting the ability of TNF-alpha agents to result in substantial and sustained improvement in symptoms of psoriatic arthritis. Agents including infliximab and etanercept result in not only clinical improvement but also slow the radiographic progression…

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   Aug 27, 2008

   14 min
6. 1

   Episode 1: TNF-Alpha: Concept to Proof of Concept

   Professor Sir Ravinder Maini's groundbreaking work on the characterization of TNF-alpha began in the mid-1980's with his collaboration with Professor Mark Feldman. In his study of intercellular messenger molecules, Professor Sir Maini utilized two new technologies -- protein sequencing and cDNA...

   May 30, 2008

   14 min