PODCAST · health
BREAKING THROUGH with Madeline Bell
by Children’s Hospital of Philadelphia
Madeline Bell, CEO of the renowned Children’s Hospital of Philadelphia, takes you behind the scenes to meet the brilliant minds who are making - and supporting - incredible breakthroughs in pediatric medicine.
Episodes
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CHOP's Next Chapter
After nearly 40 years at Children’s Hospital of Philadelphia (CHOP), including 11 as CEO, Madeline Bell will retire in October. In the final episode of Breaking Through, Madeline introduces CHOP President Dr. Joe Mitchell, who will succeed her as CEO, and reflects on her time at CHOP.
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Game Plan for Giving Back: Philadelphia Eagles President Don Smolenski
For Philadelphia Eagles President and longtime Children’s Hospital of Philadelphia (CHOP) volunteer Don Smolenski, success is built on trust and care – and connecting with the community means everything. In the new episode of Breaking Through, Don joins Madeline to talk about what the team means…
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Advancing Gene Therapy: Personalized Gene Editing
When baby KJ was diagnosed with a rare metabolic disorder, the team at Children’s Hospital of Philadelphia (CHOP) had a unique treatment option for him: a personalized gene editing therapy developed in collaboration with Penn Medicine. On this episode, Madeline speaks to CHOP geneticist Dr.…
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Advancing Gene Therapy: KJ’s Story
Earlier this year, baby KJ became the first patient in the world to receive a personalized gene editing therapy, which was developed by a team at Children’s Hospital of Philadelphia (CHOP) and Penn Medicine. In June, KJ went home after spending more than 300 days at CHOP. On this episode of...
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Celebrating Pediatric Oncologist Dr. Audrey Evans
This Women’s History Month, we are celebrating the life and legacy of one of Children’s Hospital of Philadelphia’s original breakthrough makers: pediatric oncologist Dr. Audrey Evans. In 1969, Dr. Evans became the first woman to serve as Chief of CHOP’s Division of Oncology, and she went on to...
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New Frontiers in Injury Prevention
Teams at Children's Hospital of Philadelphia (CHOP) are committed to delivering breakthroughs for patients, including keeping them safe from injury – the leading cause of death and acquired disability for children. In this episode of Breaking Through, Madeline talks to CHOP expert Dr. Kristy...
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Gene Therapy for Sickle Cell Disease
Sickle cell disease is an inherited blood disorder that often causes debilitating pain and life-threatening complications. Many patients with the disease make dozens of ER visits a year, and must receive regular blood transfusions. And though recent breakthroughs in gene therapy are giving…
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Mental Health Is Health: Caring for the Whole Child
The team at Children’s Hospital of Philadelphia (CHOP) believes that mental health is just as important as physical health – and they’re working together to find solutions to the pediatric mental health crisis. In this episode of Breaking Through, Dr. Catharyn Turner, CHOP’s Medical Director of...
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Elijah’s Story: Navigating a Medical Mystery
From the time Elijah was a baby, he had many painful symptoms – and no one could determine what was wrong. But when Elijah was a toddler, his family finally found answers at Children’s Hospital of Philadelphia. In this episode of The Breakthrough Chronicles, 12-year-old Elijah and his parents…
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Tenlee’s Story: Thriving After a Heart Transplant
Tenlee was born with a rare heart condition and had a heart transplant at Children’s Hospital of Philadelphia when she was just 5 months old. And though she’s doing well today, her journey has been very challenging. In this episode of The Breakthrough Chronicles, Tenlee’s parents, Jami and Nick,...
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Kareem’s Story: Advocating for Trauma-Informed Care
While growing up in West Philadelphia, Kareem saw firsthand the devastating impact trauma and violence can have on children. In this episode of The Breakthrough Chronicles, he and Madeline discuss the sport that changed his life – and the role that hospitals like Children’s Hospital of…
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Hannah’s Story: Moving Beyond Blindness
When Hannah was a baby, she was diagnosed with a rare eye disease that usually leaves patients completely blind. But Hannah’s story turned out differently thanks to an incredible gene therapy developed at Children’s Hospital of Philadelphia and Penn Medicine. In this episode of The Breakthrough...
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Emily’s Story: Celebrating 10 Years Cancer Free
Emily was just 6 years old when she received CAR T cell immunotherapy for relapsed leukemia at Children’s Hospital of Philadelphia. Emily was the very first child to receive this groundbreaking treatment – and in 2022, she celebrated 10 years cancer free. In this episode of The Breakthrough...
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Special Bonus Episode: Addy and Lily’s Separation Story
When Addy and Lily Altobelli were born in CHOP’s Garbose Family Special Delivery Unit, they needed highly specialized care because they were conjoined – their bodies were connected at the chest wall, diaphragm and liver. After spending almost a year in intensive care at CHOP, they were separated...
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“Do What You Love”: Finding Medicines for Rare Diseases
Hematologist and oncologist Denise Adams, MD, specializes in treating vascular anomalies, which occur when arteries, capillaries, veins or lymphatic vessels fail to develop correctly. She joins Madeline to discuss what the future holds for her field – and the surprising advice that inspired her…
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“I’ve Always Loved to Ask Why”: The Power of Mitochondrial Medicine
Our mitochondria make the energy that keeps us alive. Geneticist Marni Falk, MD, joins Madeline to discuss what happens when our mitochondria don’t work properly, the breakthroughs she and her team are making for patients with mitochondrial disease, and the importance of having a strong vision…
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“There Was an Unmet Need”: Breakthroughs in Endocrinology
While growing up in Panama, Diva DeLeón-Crutchlow, MD, MSCE, always wanted to understand how things worked. She speaks to Madeline about how her curiosity led her to pursue a career in medicine – and the work she’s doing today to develop new treatments for congenital hyperinsulinism and diabetes.
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“We Have So Many Spine-Tingling Moments”: Treating Birth Defects Before Birth
Pediatric and fetal surgeon Holly Hedrick, MD, has made life-changing breakthroughs for children with congenital diaphragmatic hernia and other rare birth defects. She joins Madeline to talk about the advice her mentors shared with her along the way – and the children who continue to inspire her...
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“Research Is Our North Star”: The Future of Breakthroughs at CHOP
In 2021, Susan Furth, MD, PhD, was named CHOP’s Chief Scientific Officer, becoming the first woman in CHOP’s 166-year history to hold this prestigious role. She joins Madeline to discuss CHOP’s trailblazing Frontier Programs, the importance of mentorship, and what the future holds for research at...
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Discovered: Making Breakthroughs in Cardiac Care
The team at CHOP’s Cardiac Center has been making life-changing breakthroughs for children for many years. The center’s co-director, pediatric heart surgeon Dr. Jonathan Chen, joins Madeline to discuss his team’s latest innovations – and to share his vision for the future of pediatric cardiac care.
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Inspired: Building a World-Class Hospital, Close to Home
This fall, CHOP will celebrate an important milestone: the grand opening of its new hospital in King of Prussia, Pa. Dr. Jan Boswinkel, the Chief Operating Officer of the King of Prussia hospital, joins Madeline to talk about what this milestone means for patients, families and the community –…
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Realized: Delivering on the Promise of Gene Therapy
World-renowned hematologist and scientist Dr. Katherine High has spent much of her career focused on achieving a goal few believed was possible: developing gene therapies and getting them to patients. Dr. High joins Madeline to talk about her journey from idea to breakthrough – and what it was…
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Transformed: Repairing Birth Defects Before Birth
The idea of repairing birth defects before babies are born seemed like a radical one to many. But Dr. Scott Adzick, Director of CHOP’s Center for Fetal Diagnosis and Treatment, was determined to pursue it – and today, he’s considered a pioneer in the field of fetal surgery. He shares insights…
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Sequenced: Using Genetics to Solve Medical Mysteries
Strange symptoms with no clear cause. Medical histories that mystify even the most experienced doctors. Dr. Ian Krantz, Co-Director of CHOP’s Roberts Individualized Medical Genetics Center, specializes in solving “medical mysteries” – and he and his team have found answers for many patients who…
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Where We Are Now with Dr. Paul Offit: Vaccines
How do the COVID-19 vaccines work? How concerned should we be about the new COVID-19 variants? Dr. Paul Offit, Director of CHOP’s Vaccine Education Center, is one of the leading voices in the vaccine conversation. On this special bonus episode, he joins Madeline to discuss the COVID-19 vaccines,...
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Where We Are Now with Dr. Edward Behrens: MIS-C
In the spring, doctors began noticing a mysterious inflammatory condition in children that involved fever, rashes, diarrhea and vomiting. Now known as Multisystem Inflammatory Syndrome in Children, or MIS-C, the rare syndrome seems to be a postviral inflammatory response to COVID-19. Dr. Edward...
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Where We Are Now with Dr. Audrey Odom John: Research
Could dogs’ noses hold the answer to a better COVID-19 diagnostic test? Dr. Audrey Odom John, Chief of the Division of Pediatric Infectious Diseases at CHOP, discusses her efforts to develop a COVID-19 breathalyzer test with help from some four-legged friends – and shares the questions CHOP...
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Where We Are Now with Dr. Rebecca Harris: Testing
Testing is one of the most important tools we have to track and stop the spread of COVID-19, but it comes with many challenges. Dr. Rebecca Harris, Director of CHOP’s Infectious Disease Diagnostics Laboratory, shares the story of how CHOP developed its own COVID-19 test early in the pandemic and...
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Where We Are Now with Dr. David Rubin: Modeling
While many institutions across the country were modeling the trajectory of COVID-19 at the national level, Dr. David Rubin, and his colleagues at CHOP’s PolicyLab took a more innovative approach: They mapped the spread of the virus at the county level. More than 500 U.S. counties are included in...
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Where We Are Now with Dr. Susan Coffin: Transmission
What makes COVID-19 different from other infectious diseases? Pediatric infectious disease specialist Dr. Susan Coffin, discusses her research on how the SARS-CoV-2 virus is transmitted, talks about how the virus affects children, and shares advice to help parents and families make decisions…
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COMING SOON: Where We Are Now
In “Where We Are Now,” a five-episode special series, Madeline Bell speaks with five CHOP researchers about the COVID-19-related work they are leading – and about what gives them hope during this challenging time. With episodes focused on everything from a modeling tool that forecasts the spread…
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The Research and Lab of the Future with Dr. Beverly Davidson
Join Madeline in CHOP’s “lab of the future” in the Leonard and Madlyn Abramson Pediatric Research Center. As Director of the Raymond G. Perelman Center for Cellular and Molecular Therapeutics and Chief Scientific Strategy Officer at CHOP, Dr. Davidson is developing innovative gene therapies to...
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Using Technology to Fuel Breakthroughs: A Conversation with Dr. Bimal Desai
Ever wondered what informatics is or how CHOP is using it? Get a peek behind the curtain with CHOP’s Chief Health Informatics Officer, Dr. Bimal Desai. Madeline dives into some of CHOP’s most innovative ideas using technology, like bedside cameras for families to check in on their babies, and…
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Minds Matter: A Concussion Discussion with Dr. Christina Master
Madeline has an in-depth conversation with Dr. Christina Master about CHOP’s interdisciplinary approach to concussion, including exciting, cutting-edge diagnosis and treatment options. Concussion Care for Kids: Minds Matter is a specialized program developed to help families, healthcare…
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Fueling Breakthroughs: Leonard Abramson
Every day approximately 700 CHOP employees go to work in the Leonard and Madlyn Abramson Pediatric Research Center, our first research building – one of them is Madeline. She sits down with Leonard to talk about his family’s 30-year relationship with the hospital and how their support has fueled...
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Brain Tumor Awareness Month with Dr. Storm and Dr. Resnick
At Children’s Hospital of Philadelphia (CHOP), researchers and doctors are working side by side to improve outcomes for children with brain tumors. In honor of Brain Tumor Awareness Month, Madeline recently sat down with Dr. Phillip “Jay” Storm, Chief of CHOP’s Division of Neurosurgery, and Dr....
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Eagles Autism Challenge
April is World Autism Awareness Month, and here at Children’s Hospital of Philadelphia, Madeline is serving as Honorary Captain for the Eagles Autism Challenge, a bike ride and run/walk that will be held in Philadelphia on May 18. The money raised at the challenge will help our scientists make...
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Pediatric Lymphatic Imaging and Interventions and Lymphatic Research: Dr. Yoav Dori
The lymphatic system is something we all have in our bodies, but very little is known about it. In this episode, Madeline is joined by Dr. Yoav Dori, Director of Pediatric Lymphatic Imaging and Interventions and Lymphatic Research at Children’s Hospital of Philadelphia. Dr. Dori and his team have...
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Center for Applied Genomics: Dr. Hakon Hakonarson
In this episode, Madeline is joined by Dr. Hakon Hakonarson, the founder and director of the Center for Applied Genomics (CAG) at Children’s Hospital of Philadelphia (CHOP). Dr. Hakonarson leads one of the world’s largest genetics research programs. His team is working to identify the genes that...
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Female Scientists Part 2: Advice To Aspiring Scientists
In part 2 of a special two-part episode, Madeline is rejoined by four female scientists from Children’s Hospital of Philadelphia. Dr. Deborah French, Dr. Allison Curry, Dr. Renata Pellegrino da Silva and Dr. Julia Parish-Morris talk about their own personal journeys and offer advice to aspiring...
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Female Scientists Part 1: Behind The Breakthroughs
Teams at CHOP have been making amazing scientific breakthroughs for more than 160 years. Many of those teams are led by women who have inspired other women to choose careers in healthcare and science. In part 1 of a special two-part episode, Madeline speaks to four female scientists from…
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Separating Conjoined Twins: Dr. Gregory Heuer and Dr. Jesse Taylor
Abby and Erin Delaney were born in the Garbose Family Special Delivery Unit at Children’s Hospital of Philadelphia on July 24, 2016. The twins had a very rare condition called craniopagus – which means they were connected at the tops of their heads. In this episode, Madeline talks to Dr. Gregory...
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Dr. Lucy Rorke-Adams: A Pioneer in Neuropathology
In this episode, Madeline talks to one of her personal heroes, Dr. Lucy Rorke-Adams, a pioneer in the field of neuropathology. Dr. Rorke-Adams’ career at CHOP spanned 50 years, and she retired just three years ago at age 86. There isn’t much she hasn’t seen – she even examined Albert Einstein’s...
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Pediatric Behavioral Health and Suicide Prevention
September is National Suicide Prevention Month, and organizations and advocates from across the country are working together to advance the conversation about behavioral health. Tami Benton, MD, Psychiatrist-in-Chief and Chair of the Department of Child and Adolescent Psychiatry and Behavioral...
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Gene Therapy and Bone Marrow Transplants for Sickle Cell Disease
In this episode of Breaking Through, Madeline speaks with Children’s Hospital of Philadelphia (CHOP) researchers Stefano Rivella, PhD, and William Peranteau, MD, about gene therapy and fetal bone marrow transplants to cure sickle cell disease. She also talks about how CHOP’s Daisy Days…
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Wawa President & CEO and CHOP Corporate Council Co-Chair Chris Gheysens
In this episode of Breaking Through, Madeline speaks with Chris Gheysens, President & CEO of Wawa and Co-Chair of Children’s Hospital of Philadelphia’s Corporate Council. Learn about the long history between CHOP and Wawa, find out how the Wawa Coffee & Care Cart is making a difference for…
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CAR T-Cell Immunotherapy for Cancer
In this episode of Breaking Through, Madeline talks to Stephan Grupp, MD, PhD, Director of the Cancer Immunotherapy Program and Section Chief of the Cellular Therapy and Transplant Program at Children’s Hospital of Philadelphia (CHOP). She also speaks with the family of a child who received CAR...
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COMING SOON: BREAKING THROUGH with Madeline Bell
Children’s Hospital of Philadelphia makes breakthroughs every day! In this podcast series, Madeline Bell, CHOP’s President & CEO, will take you behind the scenes to meet the people behind the breakthroughs. You’ll get to know CHOP's world-renowned scientists, amazing doctors and nurses. You’ll…
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ABOUT THIS SHOW
Madeline Bell, CEO of the renowned Children’s Hospital of Philadelphia, takes you behind the scenes to meet the brilliant minds who are making - and supporting - incredible breakthroughs in pediatric medicine.
HOSTED BY
Children’s Hospital of Philadelphia
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Frequently Asked Questions
How many episodes does BREAKING THROUGH with Madeline Bell have?
BREAKING THROUGH with Madeline Bell currently has 48 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is BREAKING THROUGH with Madeline Bell about?
Madeline Bell, CEO of the renowned Children’s Hospital of Philadelphia, takes you behind the scenes to meet the brilliant minds who are making - and supporting - incredible breakthroughs in pediatric medicine.
How often does BREAKING THROUGH with Madeline Bell release new episodes?
BREAKING THROUGH with Madeline Bell has 48 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to BREAKING THROUGH with Madeline Bell?
You can listen to BREAKING THROUGH with Madeline Bell on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts BREAKING THROUGH with Madeline Bell?
BREAKING THROUGH with Madeline Bell is created and hosted by Children’s Hospital of Philadelphia.
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