Butts & Guts: A Cleveland Clinic Digestive Health Podcast

Intestinal transplants are saving lives, and the field has never been more advanced. Masato Fujiki, MD, Surgical and Program Director of the Intestinal Transplant Program at Cleveland Clinic, breaks down why rejection rates have dropped dramatically, and how transplant oncology is opening doors for cancer patients.

Chronic pelvic pain affects millions of people, but its deep connection to digestive health is often overlooked. Dr. Ashley Gubbels, Director of the Center for Endometriosis and Chronic Pelvic Pain at Cleveland Clinic, joins the Butts & Guts podcast to explore how conditions like irritable bowel syndrome, endometriosis, and gut microbiome imbalances can interact with and amplify pelvic pain. Listen to learn how patients are finding relief — and hope.

In this episode of Butts & Guts, Kristin Louden, an Obesity Medicine nurse practitioner at Cleveland Clinic, cuts through the noise surrounding GLP-1 weight loss medications. She clears up common myths from social media, discusses the results patients can realistically expect and shares what other options are available if GLP-1 medicines aren’t a good fit.

Dr. Alejandro Pita, director of Living Donor Liver Transplantation at Cleveland Clinic's Transplant Center, joins Butts & Guts to talk about advancements in living donor liver transplants. He covers new innovations in the field, the growing role of robotics, qualifications for becoming a living donor and the benefits of receiving a liver from a living donor.

Cleveland Clinic colorectal surgeon Dr. Anna Spivak returns to the Butts & Guts podcast to break down everything you need to know about rectal prolapse. Dr. Spivak discusses warning signs to watch for, how it’s diagnosed, when it’s time to see a doctor and available treatment options. Listen to learn how you can reduce your risk of rectal prolapse.

Dr. Michael Valente, colorectal surgeon at Cleveland Clinic, joins this episode of Butts & Guts to discuss advances in rectal cancer care. He explores the key differences between rectal and colon cancer, why rectal cancer requires a unique clinical approach, and the current treatment options available for rectal cancer patients. Listen to learn why early screening and detection can make all the difference in rectal cancer outcomes.

Dr. Joseph Trunzo, colorectal surgeon at Cleveland Clinic, joins this episode of Butts & Guts to share key strategies for reducing your risk of colorectal cancer. He discusses the importance of early screening and detection, lifestyle modifications, knowing your family history, and how to identify symptoms of colorectal cancer. Join us to learn about the latest advancements in treatment, and why rates of colorectal cancer continue to rise among young adults. 

At age 43, Tim Beckner was a healthy young father and husband.  After a mild case of diverticulitis, he scheduled a colonoscopy at his doctor's recommendation. Tim was shocked by the results of the screening. He had colorectal cancer, even though he had no symptoms of the disease. Tim joins Dr. Steele and his colorectal surgeon, Dr. Ajaratu (AJ) Keshinro on this episode of Butts & Guts to share his inspiring story and advice he shares with others about the importance of getting screened.

Menopause can bring many changes to your body, including your digestive health. Cleveland Clinic Ob/Gyn, Dr. Catherine Caponero, joins the Butts & Guts podcast to explain why and how menopause (and perimenopause) often causes digestive issues like bloating, constipation, heartburn, food sensitivity and more. She also discusses helpful tips for feeling better during this transition.

Dr. Anthony de Buck, Section Head of IBD for the Department of Colorectal Surgery at Cleveland Clinic, joins Butts & Guts to discuss the latest surgical advances for treating Crohn's disease. Dr. de Buck explains when surgery might be needed, what new techniques are available and how these improvements help patients recover faster with better outcomes. Listen to learn what’s on the horizon to treat this chronic inflammatory disease.

On this episode of Butts & Guts, Cleveland Clinic gastroenterologist, Carole Macaron, MD, discusses a new tool designed to calculate the risk of early onset colorectal cancer, helping identify those who may develop the disease before age 45. Dr. Macaron explains how this Cleveland Clinic-developed risk predictor works, and why early detection is crucial in combating the rising rates of colorectal cancer in younger adults.

Dr. Matthew Peebles, a general surgeon for the Digestive Disease Institute at Cleveland Clinic, discusses incidental adrenal nodules (usually discovered by accident) and why many people have them without knowing. Listen to learn more about incidental adrenal nodule symptoms, risk factors, which nodules are potentially dangerous and when treatment might be necessary.

Dr. Cara King, section head of Minimally Invasive Gynecologic Surgery and Medical Gynecology at Cleveland Clinic, joins this episode of Butts & Guts to explore the relationship between gut health and endometriosis. She discusses why improving your gut health may help reduce symptoms and explains why endometriosis is so underdiagnosed and misunderstood.

Cleveland Clinic Florida gastroenterologist, Dr. Roberto Gonzalez, joins the Butts & Guts podcast to explore Barrett's Esophagus, a condition where chronic acid reflux causes changes to the esophageal lining that can increase cancer risk. Listen in as he discusses the warning signs, why early detection matters, and the latest treatment options that can help patients manage this condition effectively.

Cleveland Clinic dietitian, Julia Zumpano, joins the Butts & Guts podcast to share expert tips on eating healthy for the holidays without sacrificing flavor or the joy of seasonal favorites. Learn how to balance indulgence with healthy choices and make simple swaps to keep your nutrition goals in check this holiday season.

Dr. Tilak Shah is an interventional endoscopist and medical director of the Pancreas Center at Cleveland Clinic Florida. He joins this episode of Butts & Guts to discuss pancreatic cysts. Listen to learn more about what causes pancreatic cysts, how they are diagnosed and treated, and what types have the potential of turning into cancer.

Pregnancy brings many changes to your body, including your digestive health. Cleveland Clinic Ob/Gyn, Dr. Erica Newlin, joins this episode of the Butts & Guts podcast to explain why and how pregnancy often causes heartburn, constipation, hemorrhoids and more. Listen in to learn helpful tips for feeling more comfortable during pregnancy.

What is chronic acid reflux, or gastroesophageal reflux disease (GERD), and what causes it? Join Cleveland Clinic Florida gastroenterologist Jeffrey Steiner, MD, as he discusses, causes, symptoms, treatment options, prevention and the risks of leaving chronic acid reflux untreated.

Food Fear in patients with inflammatory bowel disease (IBD) can lead to poor nutrition, restrictive eating, worsened gut health, stress and anxiety. Madison Simons, PsyD, a gastrointestinal (GI) psychologist for the Department of Gastroenterology, Hepatology and Nutrition at Cleveland Clinic, joins the Butts & Guts podcast to explore food fear, why it happens to IBD patients and ways it can be managed.

Daphne Spyropoulos, PhD, a gastrointestinal (GI) psychologist in the Department of Gastroenterology, Hepatology and Nutrition at Cleveland Clinic, joins this episode of the Butts and Guts podcast to discuss the psychological impacts of having GI disorders, particularly those unique to women. Listen to learn why women are at a higher risk of mental health issues when it comes their digestive conditions.

Dr. Ajaratu (AJ) Keshinro, colorectal surgeon at Cleveland Clinic, joins this episode of Butts & Guts to share updates in immunotherapy as a treatment for colorectal cancer. She discusses how these treatments reactivate the immune system against cancer cells and what sets them apart from other cancer treatments. Join us to get the scoop on the latest research and what it means for the future of immunotherapy.

Dr. Shreya Gupta, a colorectal surgeon for Cleveland Clinic’s Digestive Disease Institute, joins the Butts and Guts podcast to discuss hemorrhoids. Explore the symptoms, diagnosis and current treatment options for this condition and learn how diet and lifestyle modifications can greatly reduce the likelihood of having hemorrhoids.

On this episode of Butts & Guts, Mayank Roy, gastrointestinal surgeon, surgical director of the Pancreas Center, and program director of Education & Robotic Surgery at the Digestive Disease Institute (DDI) at Cleveland Clinic Florida, explores pancreatic neuroendocrine tumor (pancreatic NETs). Listen in to learn how pancreatic NETs differ from other types of pancreatic cancer.

Dr. Benjamin Cohen is the co-section head and clinical director for Inflammatory Bowel Disease in the Department of Gastroenterology, Hepatology and Nutrition at Cleveland Clinic. He joins this episode of the Butts and Guts podcast to share updates in advanced therapies to treat inflammatory bowel disease (IBD). Learn how these treatments are improving outcomes for IBD patients.

On this episode of Butts & Guts, Cleveland Clinic colorectal surgeon, Haniee Chung, MD, discusses current treatment options for recurrent colorectal cancer. Dr. Chung also explores the factors that influence the likelihood of colorectal cancer returning.

On this episode of Butts and Guts, Dr. Steele sits down with Kendra Weekley, RD, registered dietitian at Cleveland Clinic, to explore the latest research surrounding optimal nutrition for gut health. They also discuss the influence our gut microbiome has on brain function, mood regulation, immune system strength and more!

Jessica Woodford, PhD, is a clinical psychologist in the Department of Colorectal Surgery at Cleveland Clinic. She joins this episode of the Butts and Guts podcast to discuss the emotional impacts of living with a stoma. Listen to learn more about the importance of mental health care for stoma patients, as well as the programs Cleveland Clinic offers to provide emotional support. 

Due to the rising rates of obesity and diabetes, about 30% of the population now has nonalcoholic fatty liver disease, now known as MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease). Dr. Sobia Laique, gastroenterologist and transplant hepatologist at Cleveland Clinic, joins Butts and Guts to discuss this disease along with exciting new advances in treatment and management of the condition.

Dr. Jacob Kurowski, a pediatric gastroenterologist for Cleveland Clinic Children’s, joins the Butts & Guts podcast to discuss juvenile polyposis syndrome (JPS), a genetic disorder causing polyps in the digestive tract. Explore the symptoms, diagnosis and current treatment options for JPS and learn why ongoing monitoring (from childhood through adulthood) is crucial to keeping this condition under control.

Is metabolic and bariatric surgery right for you? On this episode of Butts & Guts, Cleveland Clinic general surgeon, Dr. Rickesha Wilson, discusses current surgical options for health and weight improvement. Listen in to learn what to expect before, during and after these weightless procedures.

Join Cleveland Clinic colorectal surgeon Dr. Olga Lavryk, MD, as she discusses J-Pouch and redo J-Pouch surgery. This reconstructive procedure allows normal bowel movements for patients who have had their whole colon removed due to serious disease. Join this episode of Butts & Guts to learn about the benefits, side effects and risks associated with J-Pouch and redo J-Pouch surgery.

On this episode of Butts and Guts, Cleveland Clinic gastroenterologist Dr. Christine Lee breaks down everything you need to know about preparing for a colonoscopy. This important screening doesn't have to be intimidating. Dr. Lee walks you through the entire process with clear explanations and will put your mind at ease. Whether you're scheduled for your first colonoscopy or looking for ways to make your next one easier, this podcast provides compassionate, practical advice to help you navigate the preparation process with confidence.

Dr. Gloria Gonzalez, a renowned pediatric general surgeon and leader of the surgical oncology practice at Cleveland Clinic Children's, joins Butts & Guts to discuss pediatric hepatoblastoma, a rare liver cancer impacting around 500 children each year. Discover the origins of this disease, explore the latest treatment options, and hear about groundbreaking innovations that give hope and healthier futures to kids facing this diagnosis.

Pelvic floor physical therapy is a comprehensive approach to addressing issues related to the pelvic floor, including incontinence, sexual dysfunction, pelvic pain, constipation, and more. Erika Lydon, PT, DPT, a pelvic floor physical therapist at the Rehab & Sports Therapy Neurological Institute at Cleveland Clinic joins this episode of Butts & Guts to share more about how physical therapy can help those looking to build or maintain a healthy pelvic floor.

Should everyone live a gluten-free lifestyle?  Tune in to this episode of Butts & Guts as Cleveland Clinic gastroenterologist Dr. Claire Jansson-Knodell dives into the world of celiac disease. Discover the key differences between celiac disease and non-celiac gluten sensitivity, understand the body's autoimmune response to gluten, and get the scoop on the latest research and potential new treatments.

Join Cleveland Clinic Florida general surgeon Dr. Eric Owings, MD, as he discusses hernia symptoms, severity, and diagnosis. Plus, learn about larger and more complex hernias of the abdominal wall and cutting-edge advancements in treatment.

On this episode of Butts & Guts, Dr. Steele is joined by Senthilkumar Sankararaman, MD, a pediatric gastroenterologist and Co-Director of Intestinal Rehab and Pediatric Nutritional Support at Cleveland Clinic Children's. Dr. Sankararaman tackles the pressing questions and challenges parents face in raising healthy kids. From common nutritional issues to vital nutrients and strategies for managing picky eaters, this episode is packed with expert insights and practical advice.

In this episode of Butts & Guts, dietitian Julia Zumpano introduces the Cleveland Clinic Diet app, a groundbreaking mobile application designed to support sustainable lifestyle and dietary changes. Developed by the Cleveland Clinic, the app features content from doctors, nutritionists, and behavioral health specialists. Tune in to learn how this app can help you achieve your health goals, and take advantage of the free 7-day trial.

On this episode of Butts and Guts, Dr. Steele is joined by Dr. Emanuela Alvarenga, a colorectal surgeon at Cleveland Clinic Florida Tradition Hospital, to discuss obstructive defecation syndrome (ODS). Discover the different types of constipation, common symptoms, and the latest treatment options available.

At age 35, John Johnson believed he was in peak physical condition. As a runner, he trained diligently for the 2023 Cleveland Marathon. However, just a few weeks later, the young father received devastating news: he had been diagnosed with colorectal cancer. John joins Dr. Steele and his colorectal surgeon Dr. David Rosen on this episode of Butts & Guts to share his inspiring story, the warning signs he noticed, and advice he shares with others about his experience.

What should you do if diet and exercise are not enough to lose weight? Should you jump straight to bariatric surgery or try a GLP-1 medication first? Natalie Larson, APRN, a nurse practitioner within the Bariatric and Metabolic Institute at Cleveland Clinic, shares more about the complexities of obesity, the treatment options available, and how to discover the path that's right for you on this episode of Butts & Guts.

Anthony Lembo, MD, a gastroenterologist and Director of Research for the Digestive Disease Institute at Cleveland Clinic, joins Butts & Guts to highlight the new Neurogastroenterology and Motility Center and explore the interaction between the nervous system and gastrointestinal tract. Listen to learn more about common symptoms of neuro-GI disorders, such as bloating, pain, constipation, and diarrhea, common triggers, and treatment options available. 

Is the low histamine diet right for everyone? Amanda Igel MS, RD, LD, a registered dietician at Cleveland Clinic, joins Dr. Steele on Butts & Guts to share more about what histamine is, how an intolerance impacts the digestive system, and the importance of working with a registered dietician to develop a personalized nutrition plan.

On this episode of Butts & Guts, Dr. Steele sits down with Dr. Brian Chen from the Cleveland Clinic's Sleep Disorder Center to explore the intriguing link between sleep and digestive health. They discuss the critical role sleep plays in overall wellness and how inadequate rest can negatively impact gut function. Join them as they uncover the latest research and practical insights on how sleep affects our digestive system.

On this episode of Butts & Guts, Dr. Steele is joined by Dr. Jessica Caldwell, Director of the Women’s Alzheimer's Movement Prevention and Research Center at Cleveland Clinic, to explore the intriguing connection between gut health and brain health. Discover how the gut-brain axis influences Alzheimer’s disease, the impact of lifestyle and diet on cognitive function, and what current research reveals about managing and preventing neurodegenerative conditions. Tune in to learn how caring for your gut may be the key to safeguarding your brain.

Abdominal pain, nausea, vomiting, diarrhea, and constipation are only a few of the side effects patients undergoing cancer treatment may experience. Dr. Renato Samala, a physician within the Department of Palliative and Supportive Care at the Cleveland Clinic, joins this episode of Butts & Guts to share more about why these side effects occur, the impact on the digestive system, and how palliative care goes beyond symptom control to address the physical, emotional and psychological effects of cancer treatment.

Bret Lashner, MD, a gastroenterologist in the Center for Inflammatory Bowel Disease at Cleveland Clinic, joins Butts & Guts this week to discuss fecal transplants. This cutting-edge procedure is used to combat severe gut infections, repair the gut microbiome, and restore the quality of life for patients battling a range of conditions. Listen to learn more about how the procedure has evolved and advancements on the horizon.

This week on Butts & Guts, we welcome back Dr. Mike Leonis of Cleveland Clinic Children's to discuss the latest updates in the diagnosis and treatment of acute liver failure (ALF). Listen to learn everything you need to know about ALF in children, including the symptoms, diagnosis, and how treatment of this life-threatening condition continues to evolve.

Dr. Choon H David Kwon, Director of Minimally Invasive Liver Surgery at Cleveland Clinic, joins the Butts & Guts podcast to discuss histotripsy, a non-invasive liver tumor treatment recently approved by the FDA. Listen to learn more about how this technology works, who is a candidate, and the future of non-invasive liver tumor treatment.

Dr. Lynn Woo, Center Director for Pediatric Urology, and pediatric surgeon Dr. Anthony DeRoss, join Butts & Guts this week to discuss the new Pediatric Colorectal & Pelvic Center at Cleveland Clinic, which offers multidisciplinary care for children with colorectal and pelvic disorders. Listen to learn more about how the center provides various treatments for chronic conditions and aims to streamline care for patients and their families.