PODCAST · science
Clinician's Roundtable
by ReachMD
Tune in to interviews with the top thought leaders in medicine exploring the clinical and professional issues that are foremost in the minds of the medical community. Join us at the Clinician's Roundtable for discussions on a vast range of topics that every medical professional should know about.
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1000
Clinical Features and Outcomes of IOFB Removal
What do large registry data reveal about outcomes after intraocular foreign body removal, and how should those findings shape surgical planning and patient counseling? In this episode of New Retina Radio Journal Club with VBS, Jordan Deaner, MD, moderates a discussion with Vaidehi Dedania, MD, and Rehan Hussain, MD, on a 2025 IRIS Registry analysis of nearly 4,800 eyes. The group reviews the delayed timeline of visual recovery, the risk of late complications, and practical guidance on staging surgical intervention and setting realistic expectations in complex trauma cases.
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999
Socioeconomic Determinants and Outcomes in Proliferative Sickle Retinopathy
Host: Maria Berrocal Guest: Audina Berrocal, MD Does socioeconomic status influence outcomes in proliferative sickle retinopathy? In this episode of Clinical Minute: Retina, host Maria Berrocal, MD, speaks with Audina "Nina" Berrocal, MD, of Bascom Palmer Eye Institute, who published a retrospective review of more than 100 patients with proliferative sickle retinopathy. They explore whether the integrated care model at Bascom Palmer may account for results that don't translate to other parts of the country. The conversation also touches on newborn screening programs in Florida and the importance of sickle cell centers in high-incidence communities.
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998
Bridging the Gap Between Evolving Science and Patient Understanding
Guest: Jason Goldman, MD Scientific uncertainty is inevitable, but how we communicate it matters. Dr. Jason Goldman, President of the American College of Physicians and liaison to the CDC Advisory Committee on Immunization Practices, shares strategies for discussing the unknown with patients transparently and effectively.
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997
Navigating NTM Lung Disease: A Patient-Centered Approach
Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Kenneth Olivier, MD, MPH Guest: Shelby MacRae, MD In patients with nontuberculous mycobacterial (NTM) lung disease, treatment decisions rarely follow a one-size-fits-all approach. In this expert-led discussion, Dr. Kenneth Olivier and Dr. Shelby MacRae join Dr. Charles Turck to explore how disease characteristics, patient priorities, and evolving clinical factors can inform individualized treatment strategies across the NTM care continuum. Dr. Olivier is the Michael E. Hatcher Distinguished Professor of Medicine, Microbiology, and Immunology at the University of North Carolina School of Medicine, where he also serves as Research Director of the Bronchiectasis and NTM Care and Research Center. Dr. MacRae is an Assistant Professor of Pulmonary and Critical Care Medicine and Director of the Environmental Lung Disease, Bronchiectasis, and NTM Program at Louisiana State University Health Sciences Center in New Orleans.
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996
Rising Colorectal Cancer in Young Adults: Implications for Screening
Guest: Christopher Cann, MD Colorectal cancer is increasingly affecting younger adults, highlighting important gaps in current screening practices. Given this alarming trend, Dr. Christopher Cann discusses how rising incidence in patients under 50 challenges traditional screening thresholds and underscores the need for earlier risk assessment. He emphasizes the importance of family history, identifying high-risk individuals who may benefit from earlier screening, and maintaining a low threshold to evaluate persistent symptoms. Dr. Cann is an Assistant Professor in the Department of Hematology Oncology at Fox Chase Cancer Center in Philadelphia, where he's also the Director of the Young Adult Cancer Program.
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995
Patient Navigators’ Role in Improving Colorectal Cancer Screening
Guest: Christopher Cann, MD Patient navigators play an increasingly vital role in improving colorectal cancer screening rates and closing gaps in preventive care. Beyond care coordination, they serve as key educators by identifying eligible patients, addressing barriers, and facilitating referrals for screening colonoscopy and other modalities. Learn more about how integrating patient navigation can enhance adherence and ultimately improve patient outcomes with Dr. Christopher Cann, Assistant Professor in the Department of Hematology Oncology and Director of the Young Adult Cancer Program at Fox Chase Cancer Center in Philadelphia.
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994
Shared Decision-Making in Colorectal Cancer Screening
Host: Gates B. Colbert, MD Guest: Sarina Schrager, MD Guest: Lashika Yogendran, MD Shared decision-making plays a critical role in improving colorectal cancer screening uptake by helping patients navigate emotional, logistical, and personal barriers to care. Joining Dr. Gates Colbert to discuss how individualized, patient-centered conversations can support screening decisions and improve completion rates are Dr. Sarina Schrager and Dr. Lashika Yogendran. Dr. Schrager is a family medicine physician at the University of Wisconsin School of Medicine and Public Health, where she focuses on preventative care, women's care, and patient-centered decision-making. Dr. Yogendran is a family medicine physician at UW Health and an Assistant Professor at the University of Wisconsin School of Medicine and Public Health, Department of Family Medicine and Community Health.
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993
Blood-Based Colorectal Cancer Screening: Where Do We Stand?
Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Aasma Shaukat, MD, MPH Despite strong recommendations for colorectal cancer screening, many eligible patients are still unscreened because of access and convenience issues. Emerging blood-based screening tests may help expand participation, but important questions remain about their ability to detect advanced precursor lesions and how they compare with established screening approaches. Joining Dr. Peter Buch to discuss the evolving role of blood-based colorectal cancer screening and what clinicians should know about these new testing strategies is Dr. Aasma Shaukat. Dr. Shaukat is the Robert M. and Mary H. Glickman Professor of Medicine at the NYU Grossman School of Medicine and the Director of Outcomes Research in Gastroenterology.
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992
Epic Aura for CRC Screening: A Real-World Perspective
Guest: Natalia Usoltseva MD, FACP, MHA Colorectal cancer screening (CRC) is one of the most powerful preventive tools in primary care, but disconnected workflows can make it difficult for both clinicians and patients to stay on track. Hear Dr. Natalia Usoltseva, a primary care provider at University of Washington Medicine, talk about how integrating Epic Aura in her organization helped create a more seamless, coordinated approach to FIT-DNA screening, follow-up, and shared decision-making.
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991
Improving CRC Screening Workflows: A PCP's Recommendations
Guest: Natalia Usoltseva MD, FACP, MHA Colorectal cancer (CRC) screening is most effective when it fits seamlessly into busy primary care workflows while still keeping patients engaged in the process. Join Dr. Natalia Usoltseva as she discusses practical ways to improve screening, from simplifying shared decision-making conversations and automating follow-up processes to ensuring patients receive the individualized support they need to stay on track with preventive care. Dr. Usoltseva is a primary care provider at University of Washington Medicine.
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990
Improving CRC Screening Conversations in Primary Care
Guest: Natalia Usoltseva MD, FACP, MHA Shared decision-making can be difficult to incorporate into already time-constrained primary care visits, especially when discussing colorectal cancer screening (CRC) options with patients. Join Dr. Natalia Usoltseva, a primary care provider at University of Washington Medicine, to hear how her practice implemented standardized decision-making tools to create more efficient, patient-centered conversations and improve colorectal cancer screening adherence.
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989
How Delayed Colorectal Cancer Screening Impacts Quality of Life
Guest: Christopher Cann, MD Delayed colorectal cancer screening can significantly impact not only clinical outcomes, but also patients’ long-term quality of life. Tune in to hear Dr. Christopher Cann share his insights on these lasting consequences, including the need for more extensive surgery and systemic therapies, the burden of chemotherapy-related toxicities, and the broader implications for patients like limitations on daily activities, work, and fertility. Dr. Cann is an Assistant Professor in the Department of Hematology Oncology at Fox Chase Cancer Center in Philadelphia, where he's also the Director of the Young Adult Cancer Program.
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988
The Clinical Consequences of Delayed Colorectal Cancer Screening
Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Christopher Cann, MD Timely colorectal cancer screening can mean the difference between prevention, cure, and advanced disease. Even delays as short as a year are associated with significantly increased risks of advanced cancer and mortality. Given this risk, Dr. Peter Buch speaks with Dr. Christopher Cann about the varying sensitives of available screening modalities, key patient barriers to adherence, and practical strategies to improve screening uptake. Dr. Cann is an Assistant Professor in the Department of Hematology Oncology at Fox Chase Cancer Center in Philadelphia, where he's also the Director of the Young Adult Cancer Program.
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987
Improving CRC Screening Uptake: An Integrated Approach
Guest: Mallik Greene, PhD A recent retrospective study evaluated how combining shared decision making and EHR-enabled workflow optimization impacted colorectal cancer (CRC) screening adherence among patients aged 45 and older. Learn more as Dr. Mallik Greene dives into the details and explains how this approach could improve patient engagement. Dr. Greene's background includes a PhD and a Postdoctoral Fellowship in Health Economics and Outcomes Research, as well as a Doctorate in Business Administration.
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986
Postcolonoscopy Colorectal Cancer: Optimizing Quality to Reduce Risk
Guest: Aasma Shaukat, MD, MPH As fecal immunochemical testing (FIT) becomes more common in colorectal cancer screening, questions remain about post-FIT follow-up, especially when colonoscopies yield negative results. To explore this further, a recent review looked at the risk of colorectal cancer postcolonoscopy and analyzed the most common reasons it may occur. Hear Dr. Aasma Shaukat, a coauthor of the review, discuss the rationale behind it and its findings, which highlighted the importance of colonoscopy quality. Dr. Shaukat is the Robert M. and Mary H. Glickman Professor of Medicine and a Professor in the Department of Population Health at NYU Grossman School of Medicine. She also serves as the Director of Outcomes Research in the Division of Gastroenterology and Hepatology at NYU Langone Health.
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985
Blood-Based Screening for Colorectal Cancer: Benefits and Limitations
Guest: Aasma Shaukat, MD, MPH Despite available options like stool-based testing and colonoscopy, colorectal cancer screening rates remain low. Blood-based testing, however, has the potential to improve adherence by offering a convenient alternative. Join Dr. Aasma Shaukat as she discusses the clinical performance of blood-based testing, its limitations, and its role in real-world settings. Dr. Shaukat is the Robert M. and Mary H. Glickman Professor of Medicine and a Professor in the Department of Population Health at NYU Grossman School of Medicine. She also serves as the Director of Outcomes Research in the Division of Gastroenterology and Hepatology at NYU Langone Health.
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984
Using FTIR to Support Accurate Tissue Assessment in Colorectal Surgery
Host: Ashley Baker, MSN, PMHNP Guest: Heather Allen, PhD Guest: Ran Li, PhD Fourier Transform Infrared (FTIR) spectroscopy is emerging as a powerful tool for distinguishing cancerous from noncancerous tissue during colorectal cancer surgery. In a recent study, Drs. Heather Allen and Ran Li leveraged a broad dataset from multiple sources to identify and validate biomarkers—most notably B1—that demonstrated strong correlation with standard pathology. Hear Drs. Allen and Li walk through their study and the implications of its findings with Ashley Baker. Dr. Allen is a Full Professor in the Department of Chemistry and Biochemistry as well as the Department of Pathology at Ohio State University in Columbus, and Dr. Li is a researcher who completed a PhD in Analytical Chemistry at The Ohio State University in 2015.
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983
Initiating Colorectal Cancer Screening Earlier: A Look at the Evidence
Guest: Theodore Levin, MD In light of guidelines for the starting age of colorectal cancer screening shifting, a recent study explored how screening outcomes compare in adults age 45 to 49 and adults over 50. Across metrics like initiation, adherence, adenoma detection, and colonoscopy yield, the evidence shows support for earlier screening. Tune in to hear Dr. Theodore Levin, Professor of Health System Science at the Kaiser Permanente School of Medicine, the Associate Director at the Kaiser Permanente Northern California Division of Research, and the Clinical Lead for Colorectal Cancer Screening for the Permanente Medical Group, break down the research.
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982
Improving Colorectal Cancer Screening Adherence: Advantages of FIT
Guest: Theodore Levin, MD For younger adults needing to get screened for colorectal cancer, fecal immunochemical testing (FIT) may help with initiation and adherence because of its speed, ease, and noninvasiveness. Hear Dr. Theodore Levin discuss FIT and its potential benefits, particularly in younger adults. Dr. Levin is a Professor of Health System Science at the Kaiser Permanente School of Medicine, the Associate Director at the Kaiser Permanente Northern California Division of Research, and the Clinical Lead for Colorectal Cancer Screening for the Permanente Medical Group.
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981
Boosting Colorectal Cancer Re-Screening: The Role of Spanish Language Navigation
Host: Ryan Quigley Guest: Mallik Greene, PhD A recent study showed that tailored Spanish-language navigation paired with the multi-target stool DNA (mt-sDNA) test can significantly improve colorectal cancer re-screening adherence among Spanish-speaking patients. Hear Ryan Quigley speak with Dr. Mallik Greene, a coauthor of the study, about how these findings could shape the future of colorectal cancer screening in Spanish-speaking populations. Dr. Greene’s educational background includes a Bachelor’s degree in Pharmacy, a PhD and a Postdoctoral Fellowship in Health Economics and Outcomes Research, and a Doctorate in Business Administration.
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980
Optimizing Colorectal Cancer Screening: A Stress Test of Current Guidelines
Guest: Pedro Nascimento de Lima, PhD Conflicting colorectal cancer screening (CRC) guidelines have sometimes led to confusion over optimal starting ages and strategies. Join Dr. Pedro Nascimento de Lima as he walks through a comprehensive modeling study that tested 26 different strategies over 4,000 scenarios to test how and when it is most effective to screen. Dr. Nascimento de Lima is an Engineer at RAND, a Professor at the RAND School of Public Policy, and an investigator with the colorectal modeling group of the Cancer Intervention and Surveillance Modeling Network.
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979
Supplement Use for Colorectal Cancer Prevention: Insights from NCCN Guidelines
Guest: Reid Ness, MD According to the NCCN Guidelines for Colorectal Cancer Screening, there is mixed evidence around the impact of vitamin D, calcium, folate, and aspirin on colorectal cancer risk. Join Dr. Reid Ness as he discusses considerations for recommending these supplements based on patient-specific factors. Dr. Ness is an Associate Professor of Medicine at Vanderbilt University Medical Center in Nashville, Tennessee, faculty with the Vanderbilt Ingram Cancer Center, and the Chairman of the committee that developed the colorectal cancer screening guidelines.
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978
Analyzing Updates from the NCCN Guidelines for Colorectal Cancer Screening
Guest: Reid Ness, MD The NCCN Guidelines for Colorectal Cancer Screening recently provided updates for patients at average and increased risk—most notably, lowering the recommended starting age from 50 to 45. Hear Dr. Reid Ness walk through the updates in depth, providing insight on screening protocols for different patient populations. Dr. Ness is an Associate Professor of Medicine at Vanderbilt University Medical Center in Nashville, Tennessee, faculty with the Vanderbilt Ingram Cancer Center, and the Chairman of the committee that developed the colorectal cancer screening guidelines.
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977
Disaster-Proofing Colorectal Cancer Screening: What We Learned from COVID-19
Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Gloria Coronado, PhD Colorectal cancer screening saw significant disruptions during the COVID-19 pandemic, a challenge that has also been reflected during natural disasters such as hurricanes and wildfires. Dr. Gloria Coronado joins Dr. Charles Turck to discuss how these kinds of crises impact screening rates and how a focus on community-based care, telehealth and home-based testing, and targeted efforts for underserved populations can strengthen resilience and ensure continuity of care during future disasters. Dr. Coronado is a Professor of Epidemiology and the Associate Director of Population Science for the University of Arizona Cancer Center in Tucson.
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976
Boosting Colorectal Cancer Screening in Rural Clinics: Insights from SMARTER CRC
Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Gloria Coronado, PhD Guest: Amanda Petrik, PhD The SMARTER CRC trial evaluated mailed fecal immunochemical (FIT) outreach and patient navigation strategies across rural clinics, analyzing how implementation factors like clinic-sent letters, consistent FIT usage, and active participation in health plan meetings impacted screening outcomes. Two authors of the study, Dr. Gloria Coronado and Dr. Amanda Petrik, join Dr. Charles Turck to discuss their findings and how these results may help guide effective, scalable screening interventions for underserved populations. Dr. Coronado is a Professor of Epidemiology and the Associate Director of Population Science for the University of Arizona Cancer Center in Tucson, and Dr. Petrik is an investigator at the Kaiser Permanente Center for Health Research in Portland, Oregon, where she focuses on cancer screening and prevention in real-world settings.
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975
Improving Colorectal Cancer Screening Rates: Strategies for Equitable Care
Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Jane McElroy, PhD Guest: Jean Wang, MD, PhD Guest: Nuha Wareg, MPH, MBBS Colorectal cancer screening remains underutilized across several underserved populations, including racial minorities and rural communities. That’s why Dr. Charles Turck speaks with Drs. Jane McElroy, Jean Wang, and Nuha Wareg to learn about practical, evidence-based strategies we can implement to improve screening uptake, reduce disparities, and promote high-quality, equitable care. Dr. McElroy is a Professor in the University of Missouri’s Family and Community Medicine Department and the Co-Director of its Rural Health Research Center, Dr. Wang is a Professor of Medicine and Surgery in the Division of Gastroenterology at Washington University School of Medicine, and Dr. Wareg serves as a Practice Facilitator for the Missouri Partnership to Improve Colorectal Cancer Screening program at the University of Missouri.
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974
Colorectal Cancer Screening: Evaluating the Cost-Effectiveness of Noninvasive Options
Host: Brian P. McDonough, MD, FAAFP Guest: Carolyn Rutter, PhD Guest: Gloria Coronado, PhD Colorectal cancer screening strategies have significantly evolved in recent years, with noninvasive options like stool and blood-based tests explored for their potential to boost adherence. Drs. Gloria Coronado and Carolyn Rutter join Dr. Brian McDonough to evaluate how these methods compare to traditional colonoscopy in terms of cost-effectiveness, accessibility, and their ability to overcome screening barriers, particularly in underserved populations. Dr. Coronado is a Professor of Epidemiology and the Associate Director of Population Science for the University of Arizona Cancer Center, and Dr. Rutter is a Professor in the Biostatistics Program and Principal Investigator for a Cancer Intervention and Surveillance Modeling Network team at Fred Hutchinson Cancer Center.
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973
Addressing Barriers to Colorectal Cancer Screening in Rural Populations
Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Michael Dougherty, MD Rural populations face unique challenges in accessing colorectal cancer screening, leaving many patients in these communities unscreened. However, mailed fecal immunochemical testing (FIT) may help address these barriers and improve adherence. Joining Dr. Peter Buch to discuss the benefits and limitations associated with FIT and its potential impact on the colorectal cancer screening landscape is Dr. Michael Dougherty. Dr. Dougherty is an Adjunct Assistant Professor in the Division of Gastroenterology and Hepatology at the University of North Carolina School of Medicine.
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972
Weighing the Environmental Impact of Colorectal Cancer Screening Methods
Host: Peter Buch, MD, FACG, AGAF, FACP Guest: A. Mark Fendrick, MD Colorectal cancer screening saves lives—but how do common methods like colonoscopy and non-invasive screening methods compare in their environmental effects? With the healthcare sector being responsible for over four percent of the global carbon footprint, researchers are looking into more environmentally friendly options that can still provide optimal outcomes for patients. Dr. Peter Buch sits down with Dr. Mark Fendrick to examine the carbon footprint of available colorectal cancer screening strategies and explore how a shift to noninvasive options could offer promising clinical and environmental impacts. Dr. Fendrick is a Professor of Internal Medicine and Health Management and Policy at the University of Michigan.
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971
Higher Risk, Lowered Age: New Colorectal Cancer Screening Guidelines
Host: John Russell, MD Guest: Richard Wender, MD From oncologists to primary care, physicians are witnessing an alarming trend in younger patients: the rising risk of colorectal cancer. To investigate this growing threat, Dr. John Russell speaks with Dr. Rich Wender, Chief Cancer Control Officer at the American Cancer Society. Dr. Wender discusses the new colorectal cancer screening guidelines set forth and the methods behind the conclusion. While comparing past guidelines, Dr. Wender considers changes in our society and environment that may be contributing to increased cancer risks in younger generations. For more information and to review the new guidelines, go to cancer.org
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970
Streamlining Colorectal Cancer Screening in OB/GYN Care
Guest: Jemel Bingham, MD Integrating colorectal cancer screening into OB/GYN care expands preventive services and supports comprehensive patient health. Tune in to hear Dr. Jemel Bingham discuss practical workflow strategies, EHR integration, and patient-centered approaches to streamline screening and follow-up care. Dr. Bingham is a board-certified OB/GYN at Hartford Hospital and other affiliated medical groups in Connecticut.
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969
Preventing Colorectal Cancer with Smart Screening
Guest: Harish Gagneja, MD Colorectal cancer often develops without symptoms, making proactive screening essential for early detection and prevention. Tune in to hear Dr. Harish K. Gagneja, a board-certified gastroenterologist in Austin, Texas, explain how patient risk, test selection, and follow-up care influence smart and effective screening strategies.
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968
The Stepping Stones to Better Colorectal Cancer Screening
Guest: Harish Gagneja, MD Colorectal cancer is highly preventable, but many eligible patients remain unscreened due to common barriers and misconceptions. Tune in to hear Dr. Harish K. Gagneja share practical, patient-centered strategies to improve screening rates through education, choice, and reducing obstacles to care. Dr. Gagneja is a board-certified gastroenterologist in Austin, Texas.
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967
Adherence to OB/GYN-Ordered CRC Screening: Real-World Insights
Guest: Mallik Greene, PhD Real-world data from a recent study show strong adherence to OB/GYN-ordered colorectal cancer (CRC) screening, including both stool DNA testing and follow-up colonoscopy. Tune in to hear Dr. Mallik Greene, an author of the study, discuss its key findings, demographic disparities, and implications for expanding screening in clinical practice. Dr. Greene's background includes a PhD and a Postdoctoral Fellowship in Health Economics and Outcomes Research as well as a Doctorate in Business Administration.
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966
How Colorectal Cancer Screening Fits into OB/GYN Care
Guest: Mallik Greene, PhD Colorectal cancer screening (CRC) rates remain below national targets, particularly among younger eligible women and underserved populations. Join Dr. Mallik Greene as he discusses the role that OB/GYNs can play in expanding access to screening and improving follow-through in clinical practice. Dr. Greene’s background includes a PhD and a Postdoctoral Fellowship in Health Economics and Outcomes Research as well as a Doctorate in Business Administration.
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965
Why Adenoma Detection Rate Matters in Colorectal Cancer Screening
Host: Brian P. McDonough, MD, FAAFP Guest: Renee Williams, MD, GI New evidence from a report published in Gastroenterology demonstrates that higher adenoma detection rates (ADR) are directly associated with improved colorectal cancer detection, reinforcing ADR as a critical quality metric. Learn more about this study and its implications for optimizing screening quality and reducing missed cancers with Dr. Brian McDonough and Dr. Renee Williams, Professor of Medicine and Associate Chair for Health Equity at the NYU Grossman School of Medicine.
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964
Infectious Disease Care Through the Lens of Patient Context
Guest: Darilyn Moyer, MD, MACP, FRCP, FIDSA, FAMWA, FEFIM How do lived experience, community dynamics, and socioeconomic realities shape infectious disease risk and patient decision making? Dr. Darilyn Moyer, Executive Vice President and Chief Executive Officer of the American College of Physicians, explains how incorporating patient context into communication and care strategies can help us better address infectious disease threats like COVID-19.
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963
Negotiation and Disruptive Innovation in Academic Allergy Practice
Presenter: Marcus Shaker, MD, MSc, FAAP, FACAAI, FAAAAI Financial and space limitations are two of the most pressing issues facing allergists and immunologists in academic practice. Fortunately, negotiation principles, like BATNA and ZOPA, and disruptive innovation tactics can help address these common issues. To learn more, we recently spoke with Dr. Marcus Shaker. Not only is he a Professor of Pediatrics and Medicine at the Dartmouth Geisel School of Medicine in New Hampshire, but he also spoke about this topic at the 2026 American Academy of Allergy, Asthma, & Immunology Annual Meeting.
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962
Gut Microbiome Mechanisms Shaping Immune Responses to Allergens
Presenter: Mustafa Ozcam, PhD Emerging research is redefining the role of the gut microbiome in food allergy and immune tolerance. Here to share some of the most groundbreaking findings is Dr. Mustafa Ozcam. He discusses how gut microbes metabolize allergenic proteins, shape immune development, and serve as potential biomarkers to predict oral immunotherapy success in food allergy patients. Dr. Ozcam is an Assistant Professor of Microbiology and Immunology at the University of Maryland School of Medicine, and he spoke about this topic at the 2026 American Academy of Allergy, Asthma, and Immunology Annual Meeting.
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961
Personalizing Peanut Oral Immunotherapy by Baseline Reactivity
Presenter: Scott Sicherer, MD Based on a randomized study, children with higher baseline thresholds of peanut reactivity achieved markedly higher rates of sustained unresponsiveness after oral immunotherapy compared with untreated peers. Learn more about this study and its clinical implications with Dr. Scott H. Sicherer. Not only is he a Professor of Pediatrics and the Director of the Jaffe Food Allergy Institute at the Icahn School of Medicine at Mount Sinai, but he also spoke about this topic at the 2026 American Academy of Allergy, Asthma, and Immunology Annual Meeting.
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960
How Biologic Insights Are Refining Severe Asthma Care
Presenter: Sally E. Wenzel, MD, ATSF Given that severe asthma management is entering a new era of biologically driven precision, Dr. Sally Wenzel joins us to discuss the complexity within Type 2 inflammation and the limitations of relying on a single biomarker assessment. She also differentiates childhood-onset allergic asthma from adult-onset disease, underscoring how age of onset—along with underlying biology—can inform therapeutic strategy. Dr. Wenzel serves as the Director of the Asthma Institute at UPMC, and she spoke about this topic at the 2026 American Academy of Allergy, Asthma, and Immunology Annual Meeting.
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959
Gene Therapy, the Future of Eye Care?
Guest: Courtney Crawford, MD, FACS Guest: Raj Maturi, MD While anti-VEGF therapy can deliver vision gains with consistent, frequent injections in clinical trials, it may be challenging to sustain this in real-world practice.1 Ocular gene therapy could be a potential option for patients with neovascular age-related macular degeneration if approved. With this approach, transgenes are delivered to the eye by adeno-associated viruses (AAVs).2-4 Learn more with Drs. Courtney Crawford and Raj Maturi, who shared their perspectives on investigational gene therapy, patient conversations, and surgical considerations at the 2025 American Academy of Ophthalmology annual meeting in Orlando, Florida. Dr. Crawford is a board-certified retina specialist and founder of Star Retina in Burleson, Texas. He previously served for 10 years as a physician in the U.S. Army, where he attained the rank of Lieutenant Colonel. Dr. Maturi is a board-certified retina specialist at the Midwest Eye Institute and founder of Retina Partners Midwest in Carmel, Indiana, where he focuses on macular, retina, and vitreous care. References: Weng CY, Singh RP, Gillies MC, Regillo CD. Optimizing visual outcomes in patients with neovascular age-related macular degeneration: the potential value of sustained anti-VEGF therapy. Ophthalmic Surg Lasers Imaging Retina. 2023;54:654–659. Petrich J, Marchese D, Jenkins C, Storey M, Blind J. …
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958
MASLD and MASH in Focus: Clinical Priorities and Promising Pathways
Guest: Peter Buch, MD, FACG, AGAF, FACP From early metabolic risks to advanced liver disease, the progressive burden associated with metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) requires timely, informed care. Hear from Dr. Peter Buch as he shares practical guidance on intervention strategies and provides a closer look at current and emerging treatments shaping patient outcomes. Dr. Buch is a board-certified clinical gastroenterologist and Associate Professor at the Frank H. Netter, MD School of Medicine at Quinnipiac University.
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957
Managing Bleeding Risk in Fracture Patients on Anticoagulation
Host: Alexandria May, PharmD, BCPS Guest: Clay Spitler, MD Fracture patients receiving anticoagulation therapy face increased risks for bleeding and complications, particularly when urgent surgical intervention is needed. That’s why understanding how fracture type, injury severity, and anticoagulant choice influence timing and management decisions is critical to optimizing outcomes. Joining Dr. Alexandria May to discuss bleeding risk assessment, anticoagulation reversal strategies, and the importance of coordinated, protocol-driven care for fracture patients on anticoagulation is Dr. Clay Spitler. He’s an orthopedic trauma surgeon and serves as Vice Chair of Clinical Affairs for the Department of Orthopedic Surgery at the University of Alabama at Birmingham.
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956
Understanding the Growing Impacts of Obesity on Patient Outcomes and Care Delivery
Guest: Sujith Cherian MD, FCCP, DAABIP With obesity rates rising to unprecedented levels, clinicians face critical challenges in managing associated complications. Hear from Dr. Sujith Cherian as he explores obesity’s systemic impact, from cardiovascular and infectious risks to medication dosing and hospital care complexities. Dr. Cherian is an Associate Professor in the Divisions of Critical Care, Pulmonary, and Sleep Medicine at University of Texas Health-McGovern Medical School. He also serves as the Director of Interventional Pulmonology and Pleural Diseases at Lyndon B. Johnson Hospital in Houston.
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955
The Hidden Respiratory Burden of Obesity: Understanding the Clinical Consequences
Guest: Sujith Cherian MD, FCCP, DAABIP Obesity introduces distinct changes to respiratory physiology that ripple across care settings—from subtle outpatient symptoms to complex ventilatory challenges in the ICU and heightened perioperative risks. Dr. Sujith Cherian explains real-world scenarios and physiologic insights to show how excess weight influences not just lung mechanics, but length of stay, postoperative recovery, and cardiopulmonary complications. Dr. Cherian is an Associate Professor in the Divisions of Critical Care, Pulmonary, and Sleep Medicine at University of Texas Health-McGovern Medical School. He also serves as the Director of Interventional Pulmonology and Pleural Diseases at Lyndon B. Johnson Hospital in Houston.
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954
MASLD Explained: A Modern Framework for a Multisystem Condition
Guest: Peter Buch, MD, FACG, AGAF, FACP Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing liver health concern that's closely linked to obesity and other cardiometabolic risk factors, yet it remains underrecognized in clinical practice. That's why Dr. Peter Buch joins us to discuss how emerging perspectives are changing the way we think about metabolic-related liver disease. Dr. Buch is a board-certified clinical gastroenterologist and Associate Professor at the Frank H. Netter, MD School of Medicine at Quinnipiac University in Connecticut.
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953
From Gut Microbe to Metabolic Modulator: The Potential Role of R. hominis in Obesity
Host: Hallie Blevins, PhD A new preclinical study investigated whether Roseburia hominis, a gut microbe often depleted in individuals with obesity, could play a direct role in regulating metabolism. Learn more as Dr. Hallie Blevins explores these findings and their potential implications for future treatment of obesity and related metabolic disorders in this AudioAbstract.
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952
Reconnecting With Patients: A Human-Centered Approach to Everyday Practice
Guest: Michael Greenberg, MD Host: Ryan Quigley What does it really mean to humanize medicine? In this candid conversation, Ryan Quigley and Dr. Michael Greenberg explore how clinicians can revive empathy, trust, and emotional connection in patient care, from intentional language shifts to brief yet meaningful moments of authentic connection. Dr. Greenberg is a dermatologist at the Illinois Dermatology Institute.
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951
Timely Surgery for Hip Fractures: Addressing Anticoagulant Challenges
Host: Steve Jackson, PharmD Guest: Anna Miller, MD Guest: Michael Weaver, MD Timely surgical intervention is critical for reducing mortality and complications in high-risk hip fracture patients. However, anticoagulation therapy often presents barriers to prompt care, requiring careful coordination and clinical judgment. Joining Dr. Steve Jackson to discuss anticoagulant reversal strategies and multidisciplinary approaches for managing high-risk fracture patients are Drs. Anna Miller and Michael Weaver. Dr. Miller is a Professor of Orthopedics and the Chair of the Department of Orthopedics at Dartmouth-Hitchcock Medical Center and the Geisel School of Medicine at Dartmouth in Lebanon, New Hampshire. Dr. Weaver is an Associate Professor of Orthopedic Surgery at Harvard Medical School, as well as the Chief of Orthopedic Trauma and Distinguished Chair in Orthopedic Surgery at Brigham and Women's Hospital in Boston.
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ABOUT THIS SHOW
Tune in to interviews with the top thought leaders in medicine exploring the clinical and professional issues that are foremost in the minds of the medical community. Join us at the Clinician's Roundtable for discussions on a vast range of topics that every medical professional should know about.
HOSTED BY
ReachMD
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