PODCAST · science
Columbia University Bio Bytes
by Columbia Biotech Society
Welcome to Bio Bytes! Tune in for interviews with prominent scientists working at the intersection of Biology, Engineering, Medicine, Computer Science, and Mathematics. Check out our sister podcast "BioWorks" (https://anchor.fm/bioworks) for great discussions on life science-related business, investing, and policy. To support our podcast: https://securepay.cuit.columbia.edu/payment/pub/sponsor-sbi/https://securepay.cuit.columbia.edu/payment/pub/sponsor-sbi/Please email [email protected] with any inquiries about Bio Bytes. Logo credit: Vivian Shi ([email protected])
Episodes
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BioBytes 45: Protecting the Genome with Alberto Ciccia: DNA Repair, Immunity, and Future Therapies
Alberto Ciccia, Professor of Genetics and Development at Columbia University, joins us to discuss how cells protect their genomes and how these pathways intersect with cancer and immunity. He explains how his lab uses CRISPR-based genome-editing tools to map the DNA damage response and uncover…
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Bio Bytes 44: AI to Bridge Biology and Medicine with Dr. Nima Aghaeepour
Dr. Nima Aghaeepour, Professor at Stanford University, discusses the nuances of working with clinical data, ways predictive models can add value to physicians and drive behavioral change, and the process of spinning scientific ideas out into startups.
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Bio Bytes 43 [BenchtoBedside Series]: Pediatric Cardiology and AI with Dr. Son Duong
In this episode of BenchtoBedside, Dr. Son Duong, Assistant Professor of Pediatrics in the Division of Pediatric Cardiology at the Mount Sinai Kravis Children’s Heart Center and Icahn School of Medicine, discusses pediatric cardiology and the evolving role of AI within the speciality. He…
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Bio BITES 42: Bites, Blood Meals, and Behavioral Switches: Decoding Mosquito Behavior with Dr. Duvall
Even if mosquitoes make your skin crawl—or you think of them as nothing more than the flying, biting pests we all can’t stand—you'll be surprised by how fascinating they really are. In this episode of Bio Bytes, Dr. Laura Duvall, Assistant Professor of Biological Sciences at Columbia University,...
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Bio Bytes 41: From Bedside to Breakthrough: Dr. Rosenblatt on Innovation and Impact in Anesthesiology
In this episode of Bio Bytes and our ongoing Bench to Bedside series, we learn about Dr. Meg Rosenblatt, Chair of the Department of Anesthesiology at Mount Sinai Morningside and West and Professor of Anesthesiology. She is recognized as the first person to deliver 20% intralipid therapy to treat...
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Bio Bytes 40: Engineering Novel Immune Circuits with Dr. Livnat Jerby
Join us for a fascinating conversation with Dr. Livnat Jerby, an Assistant Professor of Genetics at Stanford University, Chan Zuckerberg Biohub Investigator, and Paul Allen Distinguished Investigator. In this episode, Dr. Jerby shares how her lab is decoding and engineering immune circuits to...
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Bio Bytes 39 [BenchtoBedside Series]: Biomedical Informatics in Neurocritical Care with Dr. Soojin Park
Join us for an illuminating discussion with Dr. Soojin Park, an Associate Professor of Neurology (in Biomedical informatics) and an Associate Attending Physician at Columbia University. Dr. Park discusses her career trajectory in neurocritical care and biomedical informatics as well as the...
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Bio Bytes 38 [BenchtoBedside Series]: Biomedical Informatics with Dr. George Hripcsak
Join us for an enlightening conversation with Dr. George Hripcsak, the Vivian Beaumont Allen Professor of Biomedical Informatics at Columbia University. Dr. Hripcsak shares insights regarding his research in biomedical informatics, focusing on how data from electronic health records can be...
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Bio Bytes 37: Academia, Scientific Publishing, and Translational Research in Targeted Protein Degradation with Michele Pagano
Michele Pagano, Chairman of the Department of Biochemistry and Molecular Pharmacology at NYU School of Medicine, takes us through his groundbreaking research on the Ubiquitin-Proteasome System and Cullin-RING Ligases. As a leading Investigator at the Howard Hughes Medical Institute, Professor...
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Bio Bytes 36 [BenchtoBedside Series]: Nuclear Medicine and Molecular Imaging with Dr. Akiva Mintz
Join us for an inspiring discussion with Dr. Akiva Mintz, a physician-scientist whose translational research focuses on developing and personalizing cancer therapies using non-invasive molecular imaging. Learn about the role of nuclear medicine in molecular based cancer therapies and the life of…
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Bio Bytes 35: Olfactory Transduction with Stuart Firestein and More on Public Engagement with Science
Stuart Firestein, a professor of biological sciences at Columbia University, walks us through his study of the vertebrate olfactory system. Professor Firestein is a member of the American Association for the Advancement of Science. With a unique career trajectory, Professor Firestein shares his...
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Bio Bytes 34: Decoding the Regulation of Gene Expression with Professor James Manley
Join us for an inspiring episode as Professor James Manley, the Julian Clarence Levi Professor of Life Sciences at Columbia University, takes us on a journey into the intricate world of gene expression regulation in mammalian cells. Professor Manley discusses the pivotal roles of RNA-binding...
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Bio Bytes 33: Space bioinformatics and healthcare with Eliah Overbey
In which Eliah Overbey, PhD, chief scientific officer at BioAstra, and research associate at the Mason lab discusses the innovations and insights from multi-omics sequencing, specifically with regards to astronaut samples. She also shares her journey into the field of space healthcare and her…
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Bio Bytes 32: Applications of GFP and touch receptor neuron (TRN) development and function with Martin Chalfie
In which Martin Chalfie, a professor of Biological Sciences at Columbia University and Nobel laureate recognized for his contribution to the development of green fluorescent protein (GFP), and Sophia discuss the applications of GFP and his current research on the development and function of touch...
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Bio Bytes 31: The structure and functions of p53 with Carol Prives
Description: In which Sophia speaks with Carol Prives, the Da Costa Professor of Cell and Molecular Biology at Columbia University and a member of both the National Academy of Sciences and the American Academy of Arts and Sciences, about her journey researching the structure and function of the…
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Bio Bytes 30: Neurotransmitters as Post-translational Modifications with Ian Maze
In which Ian Maze, professor of Neuroscience and Pharmacological science in the Icahn School of Medicine at Mount Sinai and an investigator of the Howard Hughes Medical Institute, and Vaibhav discuss the intersection of chromatin biochemistry and neuroscience. Ian describes the diverse…
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Bio Bytes 29: Kinase Proteomics and Oncology with Neil Vasan
In which Neil Vasan, assistant professor of medicine and medical oncologist at the Columbia University Irving Medical Center, and Vaibhav discuss the biochemistry and structural biology of kinases, as well as their salience in cancer development and progression. Neil tells the story behind his...
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Bio Bytes 28: Systems Approaches to Studying Neural Circuitry with Darcy Kelley
In which Darcy Kelley, Harold Weintraub Professor of Biological Sciences, and James discuss Xenopus as a model organism for understanding the biology of behavior and evolution of neural circuits. Professor Kelley describes several ways in which contemporary methods like single-cell RNA sequencing...
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[Bioworks 3]: Biotech Incubators and the Fourth Purpose Task Force with Sam Sia
This episode is cross-posted from our new show, Bioworks, which focuses on topics in life science policy, business, entrepreneurship, and investment. Check out other episodes on Bioworks here: https://anchor.fm/bioworks
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Bio Bytes 27: Microbial Systems and Synthetic Biology with Harris Wang
In which Harris Wang, associate professor of Systems Biology at the Columbia University Irving Medical Center, and Vaibhav discuss the application of systems and synthetic biology to the study of microbial communities. He describes the motivation and application of many of his group's seminal...
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Bio Bytes 26: Precision Medicine with Adam Bass
In which Adam Bass, oncologist and inaugural director of the Columbia Center for Precision Cancer Medicine, discusses the relevance of genomic science and treatments informed by sequencing in modern cancer medicine. Among other things, Vaibhav and Adam discuss current standards of care involving...
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Bio Bytes 25: Engineering Chromatin, DNA Databases, and Neurodevelopmental Organoids with Albert Keung
In which Albert Keung, Assistant Professor in the department of Chemical and Biomolecular Engineering at North Carolina State University, shares many insights on Synthetic Biology. He touches on synthetically perturbing the chemical makeup of chromatin, designing and using DNA databases to store...
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Bio Bytes 24: Gut Microbiome Biotechnology with Zack Abbott
In which Aaron speaks with Zach Abbott, PhD, about his company ZBiotics. ZBiotics is a biotechnology start-up that is focused on engineering microorganisms for consumer benefit. Aaron and Zach talk about the company’s current product, a genetically engineered probiotic designed to breakdown...
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Bio Bytes 23: Machine Learning and Structural Biology with Mohammed AlQuraishi
In which Vaibhav speaks with Dr. Mohammed AlQuraishi, an Assistant Professor of Systems Biology at the Columbia University Irving Medical Center, about using machine learning to predict protein structure. Among other things, they discuss the direction of algorithmic development in computational...
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Bio Bytes 22: Aneuploidy and Cancer Biology with Alison Taylor
In which Vaibhav speaks with Dr. Alison Taylor, an Assistant Professor of Pathology and Cell Biology at the Columbia University Irving Medical Center, about her research on the role of aneuploidy (abnormal numbers of chromosomes) in cancer. Among other things, they discuss the basic mechanisms of...
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Bio Bytes 21: Antiviral Drug Development with Dr. Alex Chavez
In which Aaron speaks with Alex Chavez, MD-PhD about antiviral drug development. They discuss chemical strategies for protease inhibitor development and the details and rationale of a novel assay that allows for early validation of candidate drugs. Additionally Alex discusses newer collaborations...
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Bio Bytes 20: Orthopedics and Regenerative Biology Research with Stavros Thomopoulos
In which Josh speaks with Stavros Thomopoulos, PhD about biomechanical engineering at the tendon-bone interface. Dr. Thomopoulos is the director of the Caroll Laboratories for Orthopedic Surgery and the Vice Chair for Basic Science Research in Orthopedic Surgery at the Columbia University Irving...
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Bio Bytes 19: Molecular Cardiology with Andy Marks
In which Josh explores the intersection of molecular biology, structural biology, and cardiology with Dr. Andrew Marks. Dr. Marks is the Chairman of the Department of Physiology at Columbia Medical School, the Founding Director of the Wu Center for Molecular Cardiology, and a professor of...
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Bio Bytes 18: Genome Topology and Leukemia with Aaron Viny
In which Vaibhav and Dr. Aaron Viny (a clinician scientist and assistant professor at Columbia) discuss the role of Cohesin complexes in 3D genome organization and how spatiotemporal irregularities in higher order genetic structures lead to blood cancers. They talk about the importance of linage...
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Bio Bytes 17: Epigenome Editing and the Neuroepigenome with Shawn Liu
In which Vaibhav and Shawn Liu (The Joan and Paul Marks, MD ’49 Assistant Professor of Physiology and Cellular Biophysics at CUIMC) speak about the specifics of epigenome editing, from selecting the right model cells, to tool design, to loci considerations for editing experiments and much more....
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Bio Bytes 16: The Power of Single Cell Data Analysis with Dana Pe'er
In which Dana speaks with Vaibhav and Jason about the principles of single cell analysis and informatics challenges associated with it. Among other things, they discuss manifolds and data topology, Bayesian approaches and considerations in prior distribution selection in biology, matrix...
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Bio Bytes 15: Small Molecule Perturbation, Ferroptosis, Computational Chemistry, and COVID-19 treatments with Dr. Brent Stockwell
In which Vaibhav and Dr. Stockwell talk about how using small molecule screening helped uncover pioneering details about Iron influenced cell death (Ferroptosis), the therapeutic context for Ferroptosis, and ligand prediction with computational chemistry. They conclude with some discussion about...
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Bio Bytes 14: Quantifying and Representing Genetic Variation with Dr. Tuuli Lappalainen
In which Dr. Lappalainen speaks to Vaibhav and Mona about a variety of topics including her latest paper in Science, the various considerations one needs to make when interpreting statistical genomic data, and a graphical representation of genomes as opposed to the traditional linear model.
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Bio Bytes 13: CRISPR-Cas13 and Using Deep Learning to Model Gene Regulatory Networks with Dr. Xuebing Wu
In which Vaibhav, Jason, and Professor Xuebing Wu discuss the mechanism and applications of CRISPR-Cas13 and how deep learning might be used to model a unified gene regulatory network.
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Bio Bytes 12: All About Coronavirus with Dr. Vincent Racaniello (Part 2)
In which Vaibhav and Professor Racaniello continue to speak about the epidemic timeline, the use and biology of Anti-Malaria drugs against COVID-19, single cell and CRISPR based antiviral studies, and other topics, like how strong immunity to the virus is (once developed).
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Bio Bytes 11: All About Coronavirus with Dr. Vincent Racaniello
In which Vaibhav speaks to Vincent Racaniello, professor of Virology at Columbia University, about the science behind the current Coronavirus (SARS-CoV-2). Among other topics, they discuss the origins of the virus and the rationale behind current retroviral drug based approaches to treat patients.
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Bio Bytes 10: Dr. Elham Azizi Part 2
In which Vaibhav and Dr. Azizi continue their discussion on using machine learning to integrate various data modalities into sensible probabilistic and statistical models to better understand cancer genetic networks.
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Bio Bytes 9: Dr. Elham Azizi Part 1
In which Vaibhav and Dr. Elham Azizi discuss the role of machine learning, AI, and data modeling in cancer biology.
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Bio Bytes 8: Dr. It'sik Pe'er Part 2
In which Vaibhav and Jason talk to Dr. Pe'er about the central goals of Systems Biology, the projects that he's most excited about, and what sorts of coursework students should complete to prepare themselves for getting into the field
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Bio Bytes 7: Dr. It'sik Pe'er Part 1
In which Vaibhav and Jason talk to Dr. It'sik Pe'er, Associate Professor of Computer Science with cross-affiliation in the Systems Biology department, about his current projects and the emergence of computational biology
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Bio Bytes 6: Dr. Sam Sternberg - Part 2
In which Vaibhav and Jason talk to Dr. Sternberg about how computational power is advancing his work with CRISPR
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Bio Bytes 5: Dr. Sam Sternberg - Part 1
In which Vaibhav and Jason speak with Dr. Sam Sternberg about his work at the forefront of CRISPR tools development
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Bio Bytes 4: Chao Lu
In which Vaibhav speaks to Dr. Chao Lu, Assistant Professor of Genetics and Development at CUMC, about his work in the field of Epigenetics and how computation is accelerating progress in discovering novel targets for therapy.
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Bio Bytes 3: Raul Rabadan
In which Miriam Interviews Dr. Raul Rabadan about the role of computing in Systems Biology, his journey as a theoretical physicist from CERN to the Institute for Advanced Studies in Princeton, to Columbia's Systems Biology Department, and why now is the time to be excited about Systems Biology.
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Bio Bytes 2 with Nicholas Tatonetti
In which Miriam speaks to Dr. Nicholas Tatonetti, Herbert Irving Assistant Professor of Biomedical Informatics, about his research regarding EHR, his children's book Toshi Builds Consensus, and much more!
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Podcast 1: Understanding Systems Bio, Synthetic Bio, and Computational Bio, and Bioinformatics
In which Miriam, Allison, and Vaibhav go over similarities and differences between Systems Bio, Synthetic Bio, and Computational Bio, and Bioinformatics.
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Podcast 0
In which we introduce ourselves, give a brief overview of Systems Biology, and discuss the potential of the field.
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ABOUT THIS SHOW
Welcome to Bio Bytes! Tune in for interviews with prominent scientists working at the intersection of Biology, Engineering, Medicine, Computer Science, and Mathematics. Check out our sister podcast "BioWorks" (https://anchor.fm/bioworks) for great discussions on life science-related business, investing, and policy. To support our podcast: https://securepay.cuit.columbia.edu/payment/pub/sponsor-sbi/https://securepay.cuit.columbia.edu/payment/pub/sponsor-sbi/Please email [email protected] with any inquiries about Bio Bytes. Logo credit: Vivian Shi ([email protected])
HOSTED BY
Columbia Biotech Society
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Frequently Asked Questions
How many episodes does Columbia University Bio Bytes have?
Columbia University Bio Bytes currently has 47 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is Columbia University Bio Bytes about?
Welcome to Bio Bytes! Tune in for interviews with prominent scientists working at the intersection of Biology, Engineering, Medicine, Computer Science, and Mathematics. Check out our sister podcast "BioWorks" (https://anchor.fm/bioworks) for great discussions on life science-related business,...
How often does Columbia University Bio Bytes release new episodes?
Columbia University Bio Bytes has 47 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to Columbia University Bio Bytes?
You can listen to Columbia University Bio Bytes on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts Columbia University Bio Bytes?
Columbia University Bio Bytes is created and hosted by Columbia Biotech Society.
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