Deep Margin

Another rockstar joins us for a great episode talking through some of the advances in head and neck de-escalation

We're back with Chris Holsinger for part 2 of the TORS adventure

Alan Ho, Medical oncologist at MSKCC talks us through his work around Ozuriftamab Vedotin (Oz-V) and other ADC approaches. Ben criticises Will's combination approaches.

Nadeem Riaz directs the Precision Radiotherapy Initiative and leads a multidisciplinary research lab at the intersection of the DNA damage response and anti-tumor immunity. He talks us through his important paper examining mechanisms of resistance and some of the pitfalls of academia.

Yungan Tao President-Elect GORTEC, and Radiation Oncologist in Head and Neck cancer at Institut Gustave-Roussy talks us through the NICOPOSTOP trial. Will risks diplomatic incidents and out European tour continues.

The Danish Head and Neck Cancer (DAHANCA) group was established in 1976 as a working group by the Danish Society for Head and Neck Oncology. Since it has gone from strength to strength and continues to pioneer cooperative group research on a national scale! Current head Jeppe Friborg talks us through their up and coming work. Den danske gruppe for hoved- og halskræft (DAHANCA) blev etableret i 1976 som en arbejdsgruppe under Dansk Selskab for Hoved- og Halsonkologi. Siden da er gruppen gået fra styrke til styrke og fortsætter med at være pionerer inden for kooperativ gruppeforskning på nationalt plan! Nuværende leder, Jeppe Friborg, fortæller os om deres kommende arbejde.

Pierre Blanchard, Professor at Gustave Roussy and Editor of Radiotherapy and Oncology 'the green journal' joins us to discuss his recent trial

Professor and Vice-chair of Hematology and Medical Oncology, and Professor of Otolaryngology at the Winship Cancer Institute at the Emory University School of Medicine in Atlanta, Georgia. He talks us through sinonasal histologies . Ben refers Will to social services.

Superstar Kate Hutcheson, Professor in the  Department of Head and Neck Surgery at The University of Texas MD Anderson  Cancer Center. and Director of Speech Pathology and Audiology talks to us about long term outcomes and examines Will's literacy.

Chris Holsinger from Stanford gets grilled by Ben and Will on TORS history in this part 1/2 episode.

We talk ORATOR, ORATOR 2 and the genesis of evidence in TORS!

Melvin Chua joins the deeply marginal crowd to talk EBV ctDNA, its clinical use, science, gardening and islands.

Chris Nutting, Professor of Radiotherapy and leader on many pivotal trials at the ICR joins us to talk through the past 25 years of radiotherapy advances and the data underpinning these. We talk about the future and Will has some technical difficulties so there is less nonsense than usual!

Dr Glenn Hanna, Director of the Center for Cancer Therapeutic Innovation (CCTI) at Dana Faber Cancer Insitute joins us for our 10th episode and it's a cracker; Glenn talks us through the finer points of ctDNA, MRD and what the future holds for this exciting space.  

Professor Vin Paleri, Consultant Head and Neck Surgeon at The Royal Marsden Hospitals and Professor of Head and Neck Surgery at the Institute of Cancer Research talks us through salvage surgery data, patient selection and how to tame feral oncologists.

Paul Swieciki, Associate Professor from Michigan joins us for a deep dive into bispecifics. We talk future targets, current excitiement and Ben gets excited about merchandise and a potential grudge match with friend of the show hardman Ari Rosenberg. It's a belter!

David Sher, Medical Director of Radiation Oncology, Chief of Head and Neck Radiation Oncology Service at UT Southwestern joins us for a comprehensive discussion about radiotherapy and its interaction with the immune system. We cover SABR, perioperative trials and elective node irradiation; it's quite a journey!

Clare Schilling, Consultant oral and maxillofacial surgeon and honorary associate professor at the University College London Head and Neck Academic Centre (HNAC) joins us live from Birmingham, where Ben likes to holiday. We talk Weiss, D'Cruz, risk and the future. Clare invites Will and Ben to 'have a go at it' too -it's a real blast!

Jonathan Shoenfeld Director of Head and Neck and Melanoma Radiation Oncology at Dana-Farber Brigham Cancer Center, and MGB Endowed Chair in Radiation Oncology joins us for some apoptotic inhibitory catharsis and takes us down his Cambridge memory lane!

Ravi Uppalauri, Director of Head and Neck Surgical Oncology at the Brigham and Women’s Hospital and Dana-Farber Cancer Institute, talks us through his views on 2025's important perioperative trials. Ben leaps like a salmon.

Head and neck oncology rockstar Professor Kevin Harrington joins us to talk about his ESMO highlights and Will's criminal tendencies.

Professor Hisham Mehanna comperes and compares arms of COMPARE....

Ari Rosenberg, Assistant Professor at the University of Chicago and medical oncologist gives us his take on ADCs in head and neck cancer some of the latest data , Ben talks military strategy and Will gives fashion tips live from ESMO 2025 inBerlin!

Introductory episode explaining what to expect from the world's newest head and neck oncology podcast.