PODCAST · science
Diabetes Discourse
by ReachMD
As the number of Americans living with diabetes continues to rise, staying up to date on the latest diabetes research is more essential than ever to help patients achieve glucose control. With Diabetes Discourse, you’ll hear from diabetes and endocrinology experts on emerging research, diagnostic and treatment strategies, and various elements that impact a patient’s disease course, including risk factors, vitamin and mineral supplementation, physical activity, and kidney disease.Because when it comes to diabetes, glucose control is just the beginning.
Episodes
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Addressing Cardiovascular Risk in Prediabetes: Why Earlier Action Matters
Guest: John W. Ostrominski, MD, MPH Prediabetes may signal more than the future development of diabetes; it can also provide an opportunity to identify and address cardiovascular risk earlier. Here to recap his presentation at the 2026 European Association for the Study of Diabetes Annual Meeting...
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Enhancing the Metabolic Benefits of GLP-1s with Diet and Exercise
Guest: Laura Chiavaroli, PhD How might diet and exercise influence metabolic outcomes among patients taking GLP-1 medicines? To find out, we recently spoke with Dr. Laura Chiavaroli, who discussed this topic at the 2026 European Association for the Study of Diabetes Annual Meeting. She shares...
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Investigating Beta Cell Dysfunction and Immune Activity in Early T1D
Guest: Edward Phelps, PhD Residual beta cells may persist after a type 1 diabetes (T1D) diagnosis, but how well do they continue to function? Tune in to hear Dr. Edward Phelps discuss research he presented at the 2026 European Association for the Study of Diabetes Annual Meeting that examined...
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Investigating Alpha-Beta Cell Proximity and T-Cell Interactions in T1D
Guest: Vira Kravets, PhD Cellular interactions within pancreatic islets may provide important insights into the early stages and pathogenesis of type 1 diabetes (T1D). Tune in to hear Dr. Vira Kravets share research she presented at the 2026 European Association for the Study of Diabetes Annual...
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Unanswered Questions in T1D: What Immunology and Islet Research Can Tell Us
Guest: Edward Phelps, PhD Despite advances in type 1 diabetes (T1D) research, key questions remain about disease progression, immune mechanisms, and the optimal timing of intervention. Here to explore how immunology and islet research could help address these knowledge gaps is Dr. Edward Phelps....
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Hypertension in T2D: Understanding the AACE Recommendations
Guest: Scott D. Isaacs, MD FACP, FACE For patients with type 2 diabetes, the latest American Association of Clinical Endocrinology (AACE) guidance supports tailoring hypertension treatment to individual risk profiles. Dr. Scott Isaacs joins us to review updated blood pressure targets, first-line...
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Survodutide in Obesity: Insights from SYNCHRONIZE-1
Guest: Carel le Roux, MBChB, MSC, FRCP, FRCPath, PhD New findings from the SYNCHRONIZE-1 trial reveal that survodutide's impact extends beyond weight reduction, with a demonstrated decrease in liver fat and meaningful improvements across multiple markers of metabolic health in patients without…
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Addressing Cost-Related Medication Non-Adherence in Diabetes
Guest: Kimberly Narain, MD, MPH, PhD Cost-related medication nonadherence remains a significant but often hidden barrier to effective diabetes care, with out-of-pocket costs preventing patients from accessing essential therapies. Dr. Kimberly Narain joins us to explain why clinicians should look...
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Understanding Residual Cardiovascular Risk in CKD and T2D
Guest: John W. Ostrominski, MD, MPH Despite advances in glycemic management, blood pressure control, lipid lowering, and disease-modifying therapies, patients with chronic kidney disease (CKD) and type 2 diabetes continue to face substantial residual cardiovascular risk. In this program, Dr. John...
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Digital Innovation in Diabetes Prevention for Older Adults
Host: Steve Jackson, PharmD Guest: Souptik Barua, PhD Guest: Emily Johnston, MPH, PhD Can older adults successfully engage with telehealth, wearable technology, and digital health tools to prevent type 2 diabetes? In this conversation with Dr. Steve Jackson, Dr. Emily Johnston and Dr. Souptik…
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Incretin-Based Advances in Obesity and T2D Care
Guest: Javier Morales, MD, FACP, FACE For patients with obesity and type 2 diabetes (T2D), emerging incretin-based therapies that target multiple metabolic pathways are producing meaningful weight-loss outcomes. To learn more about these care strategies, tune in as Dr. Javier Morales shares key...
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Addressing Unmet Needs in Type 1 Diabetes Management
Guest: Javier Morales, MD, FACP, FACE From proactive screening to once-weekly insulin, the treatment landscape for type 1 diabetes is evolving rapidly. Join Dr. Javier Morales to hear about current and emerging care strategies in these patients, a topic he also discussed at the 2026 American...
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Diabetes Educators EmpowerED: Strategies for Optimizing Patient Outcomes With Emerging Weekly Insulin Therapies
Host: Mara Fiorio, DCN, RD, LD, BC-ADM, CDCES Guest: Diana Isaacs, PharmD, BCACP, BC-ADM, CDCES, FADCES, FCCP Guest: Richard E. Pratley, MD Learn how to optimize guideline-concordant care for patients with type 2 diabetes with this on-demand webcast—featuring the latest data on weekly insulin...
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Diabetes and CKD: Strategies for Diagnosis and Treatment
Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Ian de Boer, MD Since up to 40 percent of patients with diabetes develop diabetic kidney disease, it’s essential to know how to proactively diagnose and treat them using the latest therapeutic advances and strategies. Tune in to hear…
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Uncovering the Prevalence of Type 1 Diabetes in Older Adults
Guest: Elena Toschi, MD Approximately over the last decade, lifespans in the general population have increased, along with a rise in the prevalence of type 1 diabetes in older adult patients. Since each patient has a unique disease, the clinician should personalize and devise the best approach to...
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Concentrating on the MOMPOD Trial for Metformin Plus Insulin
Host: John Buse, MD, PhD Guest: Kim Boggess, MD The most common forms of diabetes encountered in pregnant patients include gestational diabetes and preexisting type 2 diabetes. So how does adding metformin to insulin treatment help these patients? Join Dr. John Buse as he talks about the MOMPOD...
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Utilizing Hybrid Closed-Loop Technology for T1D Pediatric Patients
Guest: R. Paul Wadwa, M.D. Since young kids have a different activity level and diet than older kids or adult patients, controlling type 1 diabetes in younger patients can be more challenging, and there tends to be more variability in their blood sugars. However, a recent study identified that...
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Semaglutide Reduces CV Events in Non-Diabetic, Overweight Patients
Host: Carol Wysham Guest: A. Michael Lincoff, MD Given the growing evidence that obesity is associated with increased cardiovascular risk, a recent study assessed the impact of semaglutide on cardiovascular outcomes in patients who are overweight or obese but do not have diabetes. Not only did...
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Overcoming Obesity: Insights from the SURMOUNT-4 Trial
Host: John Buse, MD, PhD Guest: Louis J. Aronne, MD, FTOS In the SURMOUNT-4 trial, 100 patients with obesity were on tirezpatide for 9 months, and the average weight loss was 20.9 percent. The patients were then randomized to receive either placebo with behavioral intervention or tirzepatide for...
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Strategies for Addressing Diabetes Stigma and Discrimination
Host: John Buse, MD, PhD Guest: Mary de Groot, PhD The prevalence of diabetes-related stigma is alarmingly high. In fact, four in five adults have reported experiencing some form of diabetes stigma at some point in their lives. To learn how we as healthcare providers can help reduce this burden…
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How the Artificial Pancreas Can Help Diabetic Patients
Host: Stuart Weinzimer, MD The artificial pancreas represents the integration of two separate devices: a continuous glucose monitor and an insulin pump. Learn more about this technology and how it can help improve diabetic patients’ quality of life with Dr. Stuart Weinzimer, Interim Section Chief...
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Using CGMs and Insulin Pumps to Treat Pediatric Patients with T1D
Host: Stuart Weinzimer, MD From continuous glocuose monitors to insulin pumps, there have been immense technological advancements for patients with type 1 diabetes. Learn more about how these two tools can be used to treat pediatric patients with type 1 diabetes with Dr. Stuart Weinzimer, Interim...
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Challenging the Misconception That T1D Is a Childhood-Onset Disease
Host: John Buse, MD, PhD Guest: Michael Fang, PhD According to a recent study published in the Annals of Internal Medicine, the median age of patients with type 1 diabetes is 24. However, type 1 diabetes that develops in adulthood is often mistakenly identified as type 2 diabetes, resulting in...
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Decoding Diabetes Diversity: A Study on Heterogeneity and Endotypes in T1D
Host: John Buse, MD, PhD Guest: Maria Jose Redondo, MD, PhD, MPH A recent paper focused on a variety of topics associated with type 1 diabetes, including its heterogenenity, endotypes, slowly progressive insulin-dependent diabetes, and the term type 1.5 diabetes. Dive into these topics with Dr....
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Why Hybrid Closed-Loop Insulin Therapy Should Be Offered to Pregnant T1D Patients
Host: John Buse, MD, PhD Guest: Helen Murphy, PhD There are many challenges associated with managing type 1 diabetes (T1D) in pregnant patients, which is why a recent study examined the use of an automated insulin delivery system in this patient population. Using this method, insulin doses were...
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Discussing a T2D Medication That Could Reduce Insulin Needs in T1D
Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: David Selzer, MD New research suggests that a GLP-1 receptor agonist medication, semaglutide, which has been approved for type 2 diabetes and obesity, could also be used to treat type 1 diabetes in patients. So what are the risks for...
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How Overnight Glucose Levels Impact Daily Activities in T1D Patients
Host: John Buse, MD, PhD Guest: Beth Pyatak, PhD, OTR/L According to a recent study, fluncuations in glucose levels while sleeping can directly impact type 1 diabetes patients’ ability to complete daily activities. In fact, it was found that higher variability overnight led to lower sustained...
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Breaking Down Biosimilar Insulins: A Look at the Regulatory Process and Impacts
Host: John Buse, MD, PhD Guest: Simon Heller, MD Amid the crisis around the cost of diabetes care worldwide, biosimilar insulins could help save millions of dollars and allow more patients to be treated safely and effectively. But how exactly are these products approved, and how do they compare…
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Educating Providers and Patients About Insulin Biosimilars
Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Elizabeth Cook, PharmD, AE-C, BCACP, CDCES With a shortage of insulin products in the United States, our diabetic patients are left without lifesaving medications, making this a prominent barrier in clinical practice. However, insulin...
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How Ultra-Processed Foods Increase the Risk of Type 2 Diabetes
Host: John Buse, MD, PhD Guest: Jean-Philippe Drouin-Chartier, DtP, PhD What’s the relationship between ultra-processed food consumption and the risk of developing type 2 diabetes? Find out with Dr. John Buse as he speaks with Dr. Jean-Philippe Drouin-Chartier about his research that sought to...
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Recapping a Narrative Review on the Management of Chronic Kidney Disease in T2D
Host: John Buse, MD, PhD Guest: David Cherney, MD, PhD There have been several major advances regarding the management of chronic kidney disease in patients with type 2 diabetes over the last 5 years, leading Dr. David Cherney and a team of authors to publish a narrative review on how to best...
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The Impact of RADIANT: A Deep Dive into the Study
Host: John Buse, MD, PhD Guest: Louis Philipson, MD, PhD Over the last 15 years, the monogenic diabetes registry now has over 4,000 patients involved, and from that, the RADIANT study was started to identify new kinds of rare and atypical diabetes. So how can genetics testing and the RADIANT…
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Guiding Principles of Treating Gestational Diabetes
Host: John Buse, MD, PhD Guest: David Simmons, MD Gestational hypertension is more common in preeclampsia, and there’s more chance of the baby ending up in the neonatal intensive care unit. So what can we learn from the randomized trials of women patients with gestational diabetes? Learn more…
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How Diet Can Affect the Gut Microbiome
Host: John Buse, MD, PhD Guest: Karen D. Corbin, PhD, RD One of the biggest missing links in current literature about obesity and the gut microbiome was causality. In an effort to address that gap, a recent clinical trial was conducted, and now, the results are in. So what were the key findings,...
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Key Considerations for CGM Use in Older Adults with T1D
Host: John Buse, MD, PhD Guest: Anna Kahkoska, MD, PhD Continuous glucose monitoring (CGM) can help improve glycemic management in patients with type 1 diabetes (T1D), but integrating this technology can be a complex learning process for older adults. So what do we need to consider when it comes…
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Vitamin D Can Reduce the Risk of T2D in Prediabetic Patients
Host: John Buse, MD, PhD Guest: Anastassios Pittas, MD, MS Vitamin D has numerous benefits, and according to a recent study, it can even help reduce the risk of type 2 diabetes in patients with prediabtes. Learn more about the key findings from this research with Dr. John Buse and Dr. Anastassios...
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How Hypoglycemia Can Lead to Unsafe Driving Practices in T1D Patients
Host: John Buse, MD, PhD Guest: Viral Shah, MD Severe hypoglycemia can lead to dangerous challenges, one of them being an increase in vehicular accidents. Dive into the results from a study that investigated the correlation between the prevalence of hypoglycemia while driving in adults with type…
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Investigating the Impact of Bempedoic Acid on Cardiovascular Outcomes in Statin-Intolerant Patients
Host: John Buse, MD, PhD Guest: Steven Nissen, MD Among statin-intolerant patients, treatment with bempedoic acid is associated with a lower risk of major adverse cardiovascular events according to a recent study. Dive into the study’s key findings with Dr. John Buse and Dr. Steven Nissen, who...
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Addressing Gaps to Tackle Obesity in Patients with Type 1 Diabetes
Host: John Buse, MD, PhD Guest: Elizabeth Selvin, PhD, MPH As obesity rates continue to rise in adults with type 1 diabetes, what can we do to combat this growing obstacle? Dr. John Buse speaks with an expert in the field, Dr. Elizabeth Selvin, about obesity in patients with type 1 diabetes and...
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Closing Gaps in Care for Patients with T2D & CV Disease
Host: John Buse, MD, PhD Guest: Jennifer B. Green, MD The COORDINATE Study evaluated patients with cardiovascular disease and type 2 diabetes who encounter barriers in receiving newer diabetes medications. To better understand these gaps in care, Dr. John Buse speaks with one of the researchers,...
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Maximizing Weight Loss & Minimizing Side Effects With GLP-1
Host: John Buse, MD, PhD Guest: Ania Jastreboff, MD, PhD Counseling patients with obesity who are on GLP-1 receptor agonists can be challenging. How can we leverage the biology of GLP-1 receptor antagonists to improve weight loss while avoiding side effects? Dr. John Buse speaks with a leading...
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Adapting Our Exercise Talk: Key Tips on Counseling Patients on Exercise
Host: John Buse, MD, PhD Guest: Abbie E. Smith-Ryan, PhD, CSCS*D, FNSCA There are immeasurable benefits to exercise, but the hard part for patients may be getting started. How can we help our patients make exercise a part of their lives? Dr. John Buse speaks with Dr. Abbie Smith-Ryan, a Professor...
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Insights from Obesity Canada: A Deep Dive into Guideline Updates
Host: John Buse, MD, PhD Guest: Sue Pedersen, MD, FRCPC New guidelines published by Obesity Canada take a deep dive into pharmacotherapy and feature the latest recommendations on comorbidities and decision tools. To better understand the impact of these guidelines, Dr. John Buse speaks with one…
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Key Therapeutic Insights on Semaglutide in Adolescent Obesity
Host: John Buse, MD, PhD Guest: Silva Arslanian, MD New research on once-daily semaglutide for adolescent patients with obesity may alter clinicians’ approach to care. What do we need to know? Dr. John Buse speaks with one of the study’s investigators, Dr. Silva Arslanian, from the University of...
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Explore Impacts Of Glucose-Lowering Medications in Addition to Metformin
Host: John Buse, MD, PhD Guest: Jennifer B. Green, MD What does the latest research on glycemia reduction show us about the impact of glucose-lowering medication in combination with metformin on microvascular and cardiovascular outcomes in patients with type 2 diabetes? Dr. John Buse speaks with...
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Key Insights from GRADE: Exploring Data on Glycemia Reduction in T2D
Host: John Buse, MD, PhD Guest: Deborah Wexler, MD The GRADE study demonstrated the efficacy of different treatment options for patients with type 2 diabetes. To learn more about these treatment options, Dr. John Buse joins one of the study’s investigators, Dr. Deborah Wexler from Harvard Medical...
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Breaking Down the Bionic Pancreas: A Device for Dosing Decisions for T1D
Host: John Buse, MD, PhD Guest: Steven Russell, MD, PhD Research continues to emerge on the bionic pancreas and its capabilities, and a recent study shows how it can count carbohydrates and lower A1c for patients with type 1 diabetes. To find out how it does, Dr. John Buse is joined by Dr. Steven...
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An Assessment of Automated Insulin Delivery Systems for T1D
Host: John Buse, MD, PhD Guest: Martin de Bock, PhD FRACP Recent research has explored the efficacy of open source automated insulin delivery devices for patient with type 1 diabetes. What did these results tell us? Dr. John Buse speaks with Dr. Martin de Bock, a pediatric endocrinologist at the...
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A Look at Comprehensive Telehealth for PPDM
Host: John Buse, MD, PhD Guest: Matthew Crowley, MD Can telehealth change the way we manage persistently controlled type 2 diabetes (PPDM)? Dr. John Buse speaks with Dr. Matt Crowley, an Associate Professor of Medicine in the Department of Medicine in the Division of Endocrinology, Metabolism and...
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SNAP, Food Insecurity, & Healthcare Spending: What Do We Need to Know?
Host: John Buse, MD, PhD Guest: Seth Berkowitz, MD, MPH Food assistance programs like the Supplemental Nutrition Assistance Program (SNAP) can help relieve food insecurity. But can they also lower healthcare spending? To answer this question, Dr. John Buse sits down with Dr. Seth Berkowitz from…
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ABOUT THIS SHOW
As the number of Americans living with diabetes continues to rise, staying up to date on the latest diabetes research is more essential than ever to help patients achieve glucose control. With Diabetes Discourse, you’ll hear from diabetes and endocrinology experts on emerging research, diagnostic and treatment strategies, and various elements that impact a patient’s disease course, including risk factors, vitamin and mineral supplementation, physical activity, and kidney disease.Because when it comes to diabetes, glucose control is just the beginning.
HOSTED BY
ReachMD
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