EAHAD

In this episode of EAHAD Insights, Riitta Lassila and Alberto Tosetto, Von Willebrand Disease experts, look back at 100 years of progress in VWD and discuss how historical milestones continue to shape clinical practice today.From the evolution of diagnosis and the role of bleeding assessment tools to the factors that can modify bleeding tendency beyond VWF levels, the conversation explores some of the nuances of VWD management. The discussion also considers the often-overlooked role of anaemia in haemostasis and how commonly used medications may influence bleeding risk.

Haemophilia infants’ gross motor development: are we supporting movement from the very beginning? How does haemophilia affect gross motor development during the first months of life, and could factors beyond the condition itself influence how infants learn to move and explore? In this podcast interview, we discuss the study “Haemophilia infants gross motor development: comparisons with full-term and preterm infants of the same nationality”, which assessed motor development in infants with haemophilia using the Alberta Infant Motor Scale (AIMS) with Dimitrios Syrengelas, member of the EAHAD Physiotherapists Committee.

Based on the recent study Predicting Recovery After Joint Bleeding in Persons With Bleeding Disorders, we discuss the factors that influence recovery time, the importance of early clinical assessment, and how personalised follow-up may help optimise long-term musculoskeletal outcomes. Join us as we speak with one of the author Gijs Aertssen, about the implications of their findings for everyday clinical practice and the future of comprehensive haemophilia care.Read the full article: https://onlinelibrary.wiley.com/doi/10.1111/hae.70234

In this episode, Cedric Hermans sits down with Jan Blatný, Consultant Haematologist at Masaryk University and University Hospital Brno, EHCC and EuroBloodNet Centre, and former EAHAD President (2024–2026), to explore the evolving role of Factor VIII in the management of haemophilia A in 2026. As new therapies such as emicizumab, rebalancing agents, and gene therapy reshape the treatment landscape, this conversation revisits where FVIII remains essential.

Pain is not always just physical; sometimes, it’s shaped by memory. In this episode, Merel Timmer explores a recent study by Anna Wells, Clinical Specialist Physiotherapist in Haemophilia and Allied Bleeding Disorders, on how traumatic pain memories may influence the experience of pain in the present. The research highlights a crucial but often overlooked dimension of care: the psychological and emotional layers of pain.Read the full article: https://www.tandfonline.com/doi/full/10.1080/24740527.2025.2530966

Heavy menstrual bleeding (HMB) can have a profound impact on the quality of life of women and girls with very rare coagulation factor deficiencies (VRCFDs). Understanding its underlying mechanisms, clinical manifestations, and management strategies requires a multidisciplinary approach. In this episode, you will explore HMB in the context of VRCFDs from multiple perspectives and with a multidisciplinary approach.🎥 The full module is available on the EAHAD Academy: https://academy.eahad.org/eahad/2025/e-learning-modules-2025/4190161

In this episode, Paul McLaughlin talks to Claire Forde, a specialist Occupational Therapist working in bleeding disorders. Listen to them discuss Claire's unique job role and how the occupational therapist service started in the Belfast Comprehensive Care Centre.Learn more about the service review (presented at EAHAD 2025) that Claire undertook, and how the findings of that review identify who may benefit from occupational therapy input and what care provision may look like in the future.Download the poster: https://www.eahad.org/wp-content/uploads/2026/01/EAHAD25-OT-Haemophilia-Poster-V5.pdf

In this episode, Maj Friberg Birkedal, Chair of the EAHAD Nurses Committee and Paediatric Nurse in Thrombosis and Haemostasis, discusses how the Neria™ Guard infusion set may help reduce pain and distress for children receiving emicizumab. Drawing on real-world experience, she highlights why even small innovations can make a big difference in paediatric care.📰 ​ Read the article: ⁠⁠⁠https://sciendo.com/article/10.2478/jhp-2024-0019

In this episode of "Meet the Author", Daniel C. Ogrezeanu discusses his recent paper on "Acute neuromuscular and perceptual responses to blood flow restriction exercise in adults with severe haemophilia: a pilot study". Learn more about the safety and effects of blood flow restriction exercise in people with severe haemophilia. Read the full article: https://onlinelibrary.wiley.com/doi/10.1111/hae.15084Contact the author: [email protected]

This episode features Paul Mclaughlin and Paula Loughnane interviewing him about his recent paper "Exercise-based telerehabilitation for the management of chronic pain in people with severe haemophilia: a mixed-methods feasibility study".📰 ​ Read the article: ⁠⁠https://pilotfeasibilitystudies.biomedcentral.com/articles/10.1186/s40814-024-01550-z

This episode features Johan Blokzijl and Paula Loughnane interviewing him about his recent paper "A Clinical Practice Guideline for Primary Care Physiotherapy in Patients with Haemophilia". 📰 ​ Read the article on the EAHAD Website: ⁠https://www.eahad.org/eahad-projects/physiotherapists-committee-projects/ 🎥 Watch the episode on the EAHAD Academy: https://academy.eahad.org/eahad/2024/meet-the-author-series-johan-blokzijl/4150266

Welcome to our podcast series, today we interview Maria Elisa Mancuso, Senior Hematology Consultant Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital Milan, and Yesim Dargaud, head of the Clinical Haemostasis Unit at Lyon University Hospitals and the coordinator of the French reference centre for haemophilia to discuss the critical topic of managing surgery in haemophilia patients with inhibitors. Major surgeries for this unique patient population demand specialized expertise, a coordinated multidisciplinary team, and cutting-edge therapeutic strategies. 🎥 The full module is available on the EAHAD Academy: https://academy.eahad.org/eahad/2024/module-132-surgery-in-patients-with-haemophilia/4147547

Welcome to our podcast series, today we interview Maria Elisa Mancuso, Senior Hematology Consultant Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital Milan, and Yesim Dargaud, head of the Clinical Haemostasis Unit at Lyon University Hospitals and the coordinator of the French reference centre for haemophilia to discuss the best practices for managing surgery in patients with haemophilia. 🎥 The full module is available on the EAHAD Academy: https://academy.eahad.org/eahad/2024/module-131-surgery-in-patients-with-haemophilia/4145760

This episode features Sébastien Lobet who is currently a Physiotherapist and Researcher at the Haemostasis and Thrombosis Unit at the Cliniques Universitaires Saint-Luc at Université Catholique de Louvain in Brussels, Belgium. He was also chair of the EAHAD Physiotherapists Committee.Paul Mclaughlin will interview him about his recent paper titled "ACTIVLIM-Hemo: A new self-reported, unidimensional and linear measure of activity limitations in persons with haemophilia". 📰 ​Read the full article on the Haemophilia Journal: https://onlinelibrary.wiley.com/doi/full/10.1111/hae.14705 🎥 Watch the episode on the EAHAD Academy: https://academy.eahad.org/eahad/2024/meet-the-author-sbastien-lobet/4142499

Welcome to our podcast series, today we interview Prof. Thierry VandenDriessche to discuss how to enhance the efficacy and safety of gene therapy for haemophilia A and B. Despite achieving multiyear therapeutic levels of factor VIII and factor IX in patients, challenges remain. Variability in expression, gradual decline of factor VIII levels, and frequent incidence of transaminitis present ongoing hurdles. In this episode, we delve into these challenges and discuss strategies to overcome them, with a focus on the use of adeno-associated viral vectors (AAV). We also examine the advancements and limitations of integrating vector systems, such as lentiviral vectors and CRISPR-based gene editing, in preclinical studies. These strategies aim to maintain sustained clotting factor expression, even amidst target cell division. 🎥 Watch the full module on the EAHAD Academy: https://academy.eahad.org/eahad/2024/module-12-how-can-we-improve-the-efficacy-and-saf/419034

Dive deep into understanding the Clinical Experience in Haemophilia Gene Therapy with Johnny Mahlangu. 🎥 Watch the full module on the EAHAD Academy: ⁠https://academy.eahad.org/eahad/2024/module-11-clinical-experience-in-haemophilia-gene/417335⁠

This new episode on the Basic Science of Haemophilia Gene Therapy with Paul Batty introduces the science underlying this new therapy. Itprovides an overview of different gene therapy approaches, focussing on adeno-associated viral (AAV) vectors that are used for the treatment of haemophilia. 🎥 Watch the full module on the EAHAD Academy: https://academy.eahad.org/eahad/2024/module-10-basic-science-of-haemophilia-gene-thera/411461

In this episode, we explore the complexities of managing Von Willebrand Disease in women during childbirth. This in-depth discussion goes beyond the basics, addressing the unique challenges faced by women and highlighting the essential considerations for providing optimal care. This presentation refers to all people with the ability to menstruate. 🎥 Watch the full module on the EAHAD Academy: https://academy.eahad.org/eahad/2024/module-9-peripartum-management-of-women-with-von/408873

This episode features Megan Kennedy talking with Paula Loughnane, a member of the EAHAD Physiotherapists Committee, about her recent research on the physical well-being of adults with moderate and severe haemophilia. The study delves into the realms of physical activity, fitness, and cardiometabolic risks among this population. 📰 Read the full article on the Haemophilia Journal: https://onlinelibrary.wiley.com/doi/full/10.1111/hae.14653 🎥 Watch the episode on the EAHAD Academy: https://academy.eahad.org/eahad/2024/meet-the-author-megan-kennedy/409870

This time, we're thrilled to host Valérie-Anne Chantrain, delving into her groundbreaking article "Pain interferes with daily activities, emotions and sleep in adults with severe, moderate and mild haemophilia: a national cross-sectional survey". Pain poses a significant challenge for individuals with haemophilia, impacting daily life, emotions, and even sleep. Valérie-Anne's study is an exploration within a biopsychosocial framework, shedding light on the prevalence and interference of pain in severe, moderate, and mild haemophilia. Surveying 185 respondents, the findings are eye-opening. A staggering 67% reported pain, with varying degrees across severity levels. Beyond statistics, the study unravels the intricate relationships between pain severity, interference, and health-related quality of life (HR-QoL). 📰 Read the full article on the Haemophilia Journal: ⁠ https://onlinelibrary.wiley.com/doi/abs/10.1111/hae.14747⁠ 🎥 Watch the episode on the EAHAD Academy: https://academy.eahad.org/eahad/2023/meet-the-author-valrie-anne-chantrain/404929

Welcome to the EAHAD Podcast for the "Meet the Author" series. Today, we are joined by Flora van Leeuwen, author of the article "Monitoring recovery of joints after bleeding: physical examination and ultrasound are complementary". In this episode, Magnus Aspdahl, a member of the EAHAD Physiotherapists Committee, interviews Flora about her insights and findings. 📰 Read the full article on the Haemophilia Journal: https://onlinelibrary.wiley.com/doi/full/10.1111/hae.14791 🎥 Watch the episode on the EAHAD Academy: https://academy.eahad.org/eahad/2023/meet-the-author-flora-van-leeuwen/402756

In this E-Learning podcast, you will have the opportunity to learn about the prophylactic management of patients with von Willebrand disease (VWD), a common inherited bleeding disorder. The module is presented by two experts in the field: Prof. Roberta Gualtierotti and Prof. Flora Peyvandi. 🎥 Watch the full module on the EAHAD Academy: https://academy.eahad.org/eahad/2023/module-5-prophylactic-management-of-patients-with/393918

Dive deep into understanding Menstrual Problems and Inherited Bleeding Disorders with Karin van Galen on behalf of the EAHAD Women and Girls with Bleeding Disorders Working Group. 🎥 Watch the full module on the EAHAD Academy: https://academy.eahad.org/eahad/2023/module-7-menstrual-problems-and-inherited-bleedin/405219

Gastrointestinal bleeding presents a recurrent and intricate challenge in patients with Von Willebrand Disease (VWD). In this podcast, we explore the standard of care protocols, and typical patient scenarios, with a special focus on angiodysplasia. The module is presented by Prof. Sophie Susen. 🎥 Watch the full module on the EAHAD Academy: https://academy.eahad.org/eahad/2023/module-6-module-6-how-to-manage-gastrointestinal/401306

In this podcast, we delve into the remarkable 50-year evolution of haemophilia care, as chronicled in Professor Mannucci's groundbreaking article published in JTH. We'll travel through time, exploring the distant and recent past, lingering in the present, and casting our eyes toward the future of hemophilia treatment.Our journey begins by turning back the clock to Professor Mannucci's pivotal encounter with Judith Pool and her groundbreaking discovery of the cryoprecipitation principle, setting the stage for incredible developments in haemophilia care. Don't miss this captivating exploration of the past, present, and future of haemophilia care.Join us on this extraordinary expedition. 🎥 Watch the full module on the EAHAD Academy: https://academy.eahad.org/eahad/2023/e-learning-insights/405860

E-learning Module 4 on von Willebrand disease with Luciano Baronciani and Omid Seidizadeh focuses on the diagnosis of this complex bleeding disorder. The module provides an update on the current literature regarding von Willebrand disease and covers various aspects of diagnosis, including laboratory testing, and differential diagnosis. Through this module, learners will gain a better understanding of the challenges involved in diagnosing von Willebrand disease and the importance of accurate diagnosis for the effective management of patients with this disorder.

Welcome to E-Learning module 3 on Factor VIII (FVIII) inhibitors during non-replacement therapy. Our speakers Jan Astermark And Christoph Königs will be sharing valuable insights into the pathophysiology of FVIII inhibitors, factors contributing to their development, and strategies to manage patients with FVIII inhibitors during non-replacement therapy.  Learn more and watch the full module on EAHAD Academy: https://academy.eahad.org/eahad/2023/module-3-fviii-inhibitors-during-non-replacemen/385137

Welcome to the second module of the EAHAD E-Learning Working Group podcast, where we are excited to feature Carmen Escuriola-Ettingshausen as our guest speaker. In this episode, Carmen will be discussing the topic of "ITI in the era of emicizumab". Emicizumab, a new therapeutic option for people with hemophilia A, has introduced new challenges for clinicians and patients, particularly in the realm of immune tolerance induction therapy. Carmen will delve into the impact of emicizumab on ITI therapy and provide practical insights into managing patients undergoing this treatment. So, sit back, relax, and join us in this insightful conversation with Carmen Escuriola-Ettingshausen. Do not forget to watch the full webinar on EAHAD Academy: https://academy.eahad.org/eahad/2023/module-2-iti-in-the-era-of-emicizumab/376716

Welcome to the first episode of the EAHAD Podcast, where we bring you expert insights on bleeding and clotting disorders. In this episode, we focus on the management of acute cardiovascular disorders in patients with haemophilia. Our speakers, Robert Klamroth and Cedric Hermans, are renowned experts in this field and will provide a comprehensive overview of the topic. During this episode, Cedric Hermans and Robert Klamroth will introduce the background of cardiovascular disease in haemophilia and discuss the management of a specific patient. They will also review recent literature and recommendations on this topic, highlighting the complexity of anticoagulation and antiplatelet treatment in patients with haemophilia. This podcast will be of interest to healthcare professionals who manage patients with bleeding disorders and cardiovascular diseases. We invite you to watch the full module on the EAHAD Academy: academy.eahad.org/eahad/2023/elearning-working-group/module1