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ENT Update

Ear, nose and throat head and neck medicine latest information. Weekly curated international literature, research progress and clinical updates for medical professionals. Content includes: otology, rhinology, laryngology, head and neck surgery, speech therapy, audiology, etc.

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  1. 72

    Episode 74 | 2026/06/16

    耳科與聽力學專題：Psilocybin治療耳鳴最新review(PMID:42289149,https://pubmed.ncbi.nlm.nih.gov/42289149/) | 維生素D與突發性耳聾關聯性探討(PMID:42266622,https://pubmed.ncbi.nlm.nih.gov/42266622/) | 耳鳴與生活型態因子Scoping Review(PMID:42279134,https://pubmed.ncbi.nlm.nih.gov/42279134/)

  2. 71

    Episode 73 | 2026/06/15

    頭頸外科與腫瘤學專題：喉癌手術量與存活率年度10例門檻(PMID:42286827,https://pubmed.ncbi.nlm.nih.gov/42286827/)

  3. 70

    Episode 72 | 2026/06/13

    AI在ENT專題：頭頸外科轉診深度學習演算法經濟效益分析(PMID:42277577,https://pubmed.ncbi.nlm.nih.gov/42277577/) | AI唾液腺腫瘤超音波診斷系統性回顧(PMID:42259363,https://pubmed.ncbi.nlm.nih.gov/42259363/)

  4. 69

    Episode 71-Special | 2026/06/12

    ENT特輯：預後營養指數PNI在頭頸癌的預後價值 — 臨床應用與正反辯論 | 統合分析27篇4,400名HNSCC患者(PMID:40936893,https://pubmed.ncbi.nlm.nih.gov/40936893/) | 喉癌全喉切除術PNI預測價值(Eur Arch,PMID:40739370,https://pubmed.ncbi.nlm.nih.gov/40739370/) | 喉癌輔助治療比較(ENT J,PMID:42273740,https://pubmed.ncbi.nlm.nih.gov/42273740/) | CONUT/NPS vs PNI(J Clin Med,PMID:41464825,https://pubmed.ncbi.nlm.nih.gov/41464825/) | GLIM標準優於PNI(JPEN,PMID:41620828,https://pubmed.ncbi.nlm.nih.gov/41620828/) | coSII-PNI組合評分(Curr Oncol,PMID:41590350,https://pubmed.ncbi.nlm.nih.gov/41590350/)

  5. 68

    Episode 70 | 2026/06/12

    喉科學專題：局部晚期喉癌手術vs根治性放化療(河北醫科大單中心210例,PMID:42273740,https://pubmed.ncbi.nlm.nih.gov/42273740/) | 下咽癌氣切依賴比較CRT vs手術(Laryngoscope 165例,PMID:41133918,https://pubmed.ncbi.nlm.nih.gov/41133918/)

  6. 67

    Episode 69 | 2026/06/11

    睡眠醫學專題：舌下神經刺激器與缺氧負荷(STAR trial次級分析,PMID:42166156,https://pubmed.ncbi.nlm.nih.gov/42166156/) | 睡眠呼吸中止與大腦老化回顧(PMID:42263797,https://pubmed.ncbi.nlm.nih.gov/42263797/)

  7. 66

    Episode 68 | 2026/06/10

    鼻科學專題：Dupilumab在CRSwNP的效果預測因子(OTO Open,PMID:42256728,https://pubmed.ncbi.nlm.nih.gov/42256728/) | CRSwNP生物製劑轉換真實世界經驗(ENT J,PMID:42141980,https://pubmed.ncbi.nlm.nih.gov/42141980/)

  8. 65

    Episode 67 | 2026/06/09

    耳科專題：30年兒童人工耳蝸語言發展追蹤(PMID:42256443,https://pubmed.ncbi.nlm.nih.gov/42256443/) | 彎曲型vs直線型電極長期結果比較(PMID:42256722,https://pubmed.ncbi.nlm.nih.gov/42256722/)

  9. 64

    Episode 66 | 2026/06/08

    頭頸外科與腫瘤學專題：HPV陽性口咽癌降階治療傘狀回顧(PMID:42230323,https://pubmed.ncbi.nlm.nih.gov/42230323/) | 原發治療與p16狀態口咽癌結果(PMID:42247781,https://pubmed.ncbi.nlm.nih.gov/42247781/) | ECOG-E3311長期追蹤(PMID:40493877,https://pubmed.ncbi.nlm.nih.gov/40493877/)

  10. 63

    Episode 65 | 2026/06/06

    AI在ENT專題：多模態AI在耳鼻喉科臨床應用(PMID:42117403,https://pubmed.ncbi.nlm.nih.gov/42117403/) | AI聊天機器人與ENT癌前病變病人健康資訊搜尋(PMID:42129990,https://pubmed.ncbi.nlm.nih.gov/42129990/)

  11. 62

    Episode 64 | 2026/06/05

    喉科學專題：喉癌治療光譜 — 化放療與手術選擇辯證 | 印度CRT三級吞嚥困難40%(PMID:42235117,https://pubmed.ncbi.nlm.nih.gov/42235117/) | OPHL功能保留新證據(PMID:41609393,https://pubmed.ncbi.nlm.nih.gov/41609393/) | TOLMS聲門癌94.7%喉嚨保存率(PMID:41812504,https://pubmed.ncbi.nlm.nih.gov/41812504/)

  12. 61

    Episode 63 | 2026/06/04

    睡眠醫學專題：OSA血壓軌跡與心血管風險(BP Trajectories Dual-Cohort,PMID:42219794,https://pubmed.ncbi.nlm.nih.gov/42219794/) | 糖尿病前期與OSA雙向關係回顧(Prediabetes OSA Review,PMID:42217267,https://pubmed.ncbi.nlm.nih.gov/42217267/)

  13. 60

    Episode 62 | 2026/06/03

    鼻科學專題：慢性鼻竇炎術後細菌抗藥性(PMID:42226140,https://pubmed.ncbi.nlm.nih.gov/42226140/) | 鼻竇手術範圍評分系統(PMID:42223914,https://pubmed.ncbi.nlm.nih.gov/42223914/)

  14. 59

    Episode 61 | 2026/06/02

    耳科與聽力學專題：語音噪音辨識預測大腦皮質厚度變化(PMID:42207546,https://pubmed.ncbi.nlm.nih.gov/42207546/) | 助聽器效益與失智風險33國世代研究(PMID:42127901,https://pubmed.ncbi.nlm.nih.gov/42127901/)

  15. 58

    Episode 60 | 2026/06/01

    頭頸外科與腫瘤學專題：Amivantamab復發轉移HNSCC(OrigAMI-4,PMID:42218660,https://pubmed.ncbi.nlm.nih.gov/42218660/) | 舌癌compartment切除後IHMCF重建功能評估(PMID:42218322,https://pubmed.ncbi.nlm.nih.gov/42218322/) | Integrin β1與鱗狀癌免疫逃脫轉移(PMID:42217561,https://pubmed.ncbi.nlm.nih.gov/42217561/) | 頭頸癌IMRT患者憂鬱與壓力縱貫研究(PMID:42217521,https://pubmed.ncbi.nlm.nih.gov/42217521/)

  16. 57

    Episode 59 | 2026/06/01

    頭頸外科與腫瘤學專題：補救手術與復發性頭頸癌(RESCUE,PMID:42208312,https://pubmed.ncbi.nlm.nih.gov/42208312/) | 靜脈吻合一條vs兩條統合分析(PMID:42203589,https://pubmed.ncbi.nlm.nih.gov/42203589/) | 虛擬手術計畫下頜骨ORN重建(PMID:42206699,https://pubmed.ncbi.nlm.nih.gov/42206699/) | 再次放療併用pemetrexed/erlotinib復發頭頸癌(PMID:42116977,https://pubmed.ncbi.nlm.nih.gov/42116977/)

  17. 56

    Episode 58 | 2026/05/31

    本週回顧專題：頭頸腫瘤新藥(TORPEdO,PMID:42183251,https://pubmed.ncbi.nlm.nih.gov/42183251/) | 食道癌FLOT新輔助化療(PMID:42213868,https://pubmed.ncbi.nlm.nih.gov/42213868/) | fNIRS聽損皮質評估(PMID:42192844,https://pubmed.ncbi.nlm.nih.gov/42192844/) | 兒童早期聽覺刺激(PMID:42194183,https://pubmed.ncbi.nlm.nih.gov/42194183/) | CRSwNP Radiomics評分(PMID:42188339,https://pubmed.ncbi.nlm.nih.gov/42188339/) | COMISA chronotherapy(PMID:42214833,https://pubmed.ncbi.nlm.nih.gov/42214833/) | OSA兒童中耳積水(PMID:42205832,https://pubmed.ncbi.nlm.nih.gov/42205832/) | 小兒喉氣管狹窄(PMID:42212832,https://pubmed.ncbi.nlm.nih.gov/42212832/) | 肺移植吞嚥困難(PMID:42047493,https://pubmed.ncbi.nlm.nih.gov/42047493/) | 氣切吞嚥指引(PMID:42033471,https://pubmed.ncbi.nlm.nih.gov/42033471/) | Digital Pathology HNSCC(PMID:42183917,https://pubmed.ncbi.nlm.nih.gov/42183917/) | Videomics AI喉鏡(PMID:42153409,https://pubmed.ncbi.nlm.nih.gov/42153409/)

  18. 55

    Episode 57 | 2026/05/30

    AI在ENT專題：AI口腔癌診斷(Ben Dor,PMID:42207210,https://pubmed.ncbi.nlm.nih.gov/42207210/) | AI喉鏡診斷scoping review(PMID:42153409,https://pubmed.ncbi.nlm.nih.gov/42153409/) | Gemini評估聲帶注射技術(PMID:42185941,https://pubmed.ncbi.nlm.nih.gov/42185941/) | AI助聽器病人認知討論(PMID:42190300,https://pubmed.ncbi.nlm.nih.gov/42190300/)

  19. 54

    Episode 56 | 2026/05/29

    喉科學專題：前路頸椎術後吞嚥與聲音評估(SR入路,PMID:42200633,https://pubmed.ncbi.nlm.nih.gov/42200633/) | 左側聲帶麻痺竟是主動脈瘤表現！(黴菌性動脈瘤,PMID:42206081,https://pubmed.ncbi.nlm.nih.gov/42206081/) | 咳嗽病理生理學綜述(神經免疫失調,PMID:42203561,https://pubmed.ncbi.nlm.nih.gov/42203561/)

  20. 53

    Episode 55-Special | 2026/05/28

    維生素D與頸癌特輯：UNESCO乳癌RCT維生素D化療(PMID:40098326,https://pubmed.ncbi.nlm.nih.gov/40098326/) | 維生素D增進cisplatin敏感性LCN2/NF-κB(PMID:31819048,https://pubmed.ncbi.nlm.nih.gov/31819048/) | VDR-BIM克服cisplatin抗藥HNSCC(PMID:36291915,https://pubmed.ncbi.nlm.nih.gov/36291915/) | 維生素D缺乏HNSCC預後免疫(PMID:30228945,https://pubmed.ncbi.nlm.nih.gov/30228945/) | 術前25(OH)D與喉切除術後併發症(PMID:39438295,https://pubmed.ncbi.nlm.nih.gov/39438295/) | 維生素D與HNC統合分析(PMID:33732250,https://pubmed.ncbi.nlm.nih.gov/33732250/) | 維生素D頭頸癌臨床預後系統回顧(PMID:40218858,https://pubmed.ncbi.nlm.nih.gov/40218858/) | 維生素D頭頸癌綜論(PMID:37299554,https://pubmed.ncbi.nlm.nih.gov/37299554/)

  21. 52

    Episode 54 | 2026/05/27

    睡眠醫學專題：OSA-CV綜論(PMID:42200975,https://pubmed.ncbi.nlm.nih.gov/42200975/) | CPAP預防心血管事件統合分析(PMID:42110829,https://pubmed.ncbi.nlm.nih.gov/42110829/) | CBT-I合併BZD減量(PMID:42168527,https://pubmed.ncbi.nlm.nih.gov/42168527/) | 數位CBT-I降低過度警醒(PMID:42184726,https://pubmed.ncbi.nlm.nih.gov/42184726/) | OSA種族差異系統性回顧(PMID:42196707,https://pubmed.ncbi.nlm.nih.gov/42196707/)

  22. 51

    Episode 53-Special | 2026/05/27

    ENT特輯：2026年5月一週學術精選 | CRSwNP七種生物製劑網絡統合分析(PMID:41999554,https://pubmed.ncbi.nlm.nih.gov/41999554/) | TCRF鼻閥阻塞治療24個月睡眠追蹤(DOI:10.1002/oto2.70250,https://doi.org/10.1002/oto2.70250) | 頭頸癌放療中斷7天預後影響(PMCID:PMC12679426,https://pmc.ncbi.nlm.nih.gov/articles/PMC12679426/) | 頭頸癌輔助治療時效性JAMA Oto(PMCID:PMC13087907,https://pmc.ncbi.nlm.nih.gov/articles/PMC13087907/) | TMB預測HNSCC免疫治療反應統合分析(DOI:10.1002/hed.70297,https://doi.org/10.1002/hed.70297) | 頭頸癌系統治療未來十年藍圖(DOI:10.3389/fonc.2026.1799378,https://www.frontiersin.org/articles/10.3389/fonc.2026.1799378/full) | OSA自然病程跨生命週期綜述(MDPI,https://www.mdpi.com/2227-9032/14/3/325) | 會厭形態與OSA氣道塌陷CFD研究(MDPI,https://www.mdpi.com/2227-9059/14/3/553)

  23. 50

    Episode 52 | 2026/05/26

    鼻科學專題：鼻息肉術後復發分層治療(PMID:42179747, DOI:10.62347/KYDI9328) | 單側鼻竇疾病良惡性鑑別演算法(PMID:42184393, DOI:10.24875/CIRU.24000449) | 薑製劑治療過敏性鼻炎統合分析(PMID:42183789, DOI:10.1080/13880209.2026.2667560) | Montelukast+desloratadine過敏性鼻炎網路統合分析(PMID:42182608)

  24. 49

    Episode 51 | 2026/05/26

    ENT Update Podcast 2026-05-26 (Tuesday). Topics: ISSNHL vestibular assessment, Koos grade 4 VS SRS pseudoprogression, facial palsy QoL in VS patients, Spanish VADL cross-cultural adaptation. Hosts: Dr. Fu (Puck) & Dr. Lin (Kore).

  25. 48

    Episode 50 | 2026/05/26

    ENT Update Podcast EP53 - Otology and Audiology (2026/05/26) Papers discussed: 1. vHIT and cVEMPs in sudden SNHL - Rodriguez-Izquierdo et al. Acta Otolaryngol 2026 - DOI:10.1080/00016489.2026.2671348 2. Motorized vs manual CI insertion - Hear Res 2026 - DOI:10.1016/j.heares.2026.109653 3. Pseudoprogression in Koos grade 4 VS after SRS - Schouten et al. J Neurooncol 2026 - DOI:10.1007/s11060-026-05619-y 4. Facial palsy impact on VS QoL - van Vollenhoven et al. Otolaryngol Head Neck Surg 2026 - DOI:10.1002/ohn.70255

  26. 47

    Episode 49 | 2026/05/25

    ENT Update Podcast EP52 - 頭頸外科與腫瘤學（2026/05/25） 本集論文： 1⃣️ Near-infrared fluorescence imaging-guided surgery using cRGD-ZW800 to improve surgical resection margins in oral cancer: a phase I/II feasibility trial PMID: 42173866 https://pubmed.ncbi.nlm.nih.gov/42173866/ DOI: 10.1038/s41467-026-73554-7 關鍵發現：Phase I/II trial (n=24) 顯示 cRGD-ZW800 螢光導引可即時改變口腔癌手術邊緣決策，四例病人中偵測到肉眼無法辨識的腫瘤殘留 2⃣️ De-Escalated Adjuvant Radiation Therapy in Patients With HPV-Positive Oropharyngeal Cancer PMID: 42149594 https://pubmed.ncbi.nlm.nih.gov/42149594/ DOI: 10.1001/jamanetworkopen.2026.12837 關鍵發現：NCDB 資料庫 3300+ 病人，降階放療組兩年局部控制率 93%，急性三度黏膜炎從 42% 降至 18% 3⃣️ Dissociating recurrence risk from mortality: a 10 year analysis challenging the independent prognostic value of depth of invasion in oral cavity squamous cell carcinoma PMID: 42107224 https://pubmed.ncbi.nlm.nih.gov/42107224/ DOI: 10.1016/j.oraloncology.2026.108001 關鍵發現：多變項分析中 DOI 獨立預後價值大幅衰減（HR 2.1→1.3），不應單獨用於治療決策 4⃣️ Transoral Robotic Surgery-Based Treatment Versus Definitive Chemoradiation for Oropharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis PMID: 42087273 https://pubmed.ncbi.nlm.nih.gov/42087273/ DOI: 10.1002/hed.70308 關鍵發現：TORS 組五年存活率 88% vs 放化療 85%（無顯著差異），但吞嚥功能與口乾發生率顯著較優 5⃣️ The submental artery pedicled flap for peri-auricular and parotid reconstruction: a comparative cohort PMID: 42176358 https://pubmed.ncbi.nlm.nih.gov/42176358/ DOI: 10.1016/j.oraloncology.2026.108032 關鍵發現：頦下動脈皮瓣 vs 顳肌皮瓣，美觀滿意度更高、手術時間縮短 40 分鐘、住院天數更短，皮瓣存活率 100% 6⃣️ Osteoradionecrosis After Modern Radiotherapy for Oral Cavity Cancer: Incidence and Risk Factors PMID: 42111429 https://pubmed.ncbi.nlm.nih.gov/42111429/ DOI: 10.1002/lio2.70431 關鍵發現：IMRT/VMAT 時代五年 ORN 累積發生率 7.2%，重度 ORN 2.8%；關鍵風險因子：下齒齦原發腫瘤、V6025%、放療前拔牙

  27. 46

    Episode 48-Special | 2026/05/25

    Episode 51-Special | 2026/05/25 — 頭頸部腫瘤最新研究特輯 主持人：傅醫師（Puck）& 林醫師（Kore） 本集論文： 1. 單細胞 HNSCC 惡性細胞異質性與 MCScore 預測工具 (IUBMB Life) DOI: https://pubmed.ncbi.nlm.nih.gov/42068156/ 2. STING 表現預測 LA HNSCC 治療失敗型態 (JNCI Cancer Spectrum) DOI: https://pubmed.ncbi.nlm.nih.gov/41569294/ 3. HYDRA/HYPNO 低分割放療試驗 DOI (HYDRA): https://pubmed.ncbi.nlm.nih.gov/42000366/ DOI (HYPNO): https://pubmed.ncbi.nlm.nih.gov/41711624/ 4. ctDNA MRD 監測：MERIDIAN Phase II + PECAN Trial (AACR 2026) 5. 放療中斷對預後影響 + SBRT 新技術 (JAMA Otolaryngology) DOI: https://pmc.ncbi.nlm.nih.gov/articles/PMC12679426/ 6. Rilvegostomig (TIGIT/PD-1) + MICVO ADC (AACR 2026) 7. HPV+ OPSCC 去強度策略與生物標記 DOI: https://onlinelibrary.wiley.com/doi/10.1002/cnr2.70539

  28. 45

    Episode 47 | 2026/05/25

    ENT Update, Episode 47 | 2026/05/25. ENT Head and Neck Medicine latest information.

  29. 44

    Episode 46-Special | 2026/05/23

    ENT Update Podcast 特輯 - 2026/05/23 睡眠外科最新進展 主持人：傅醫師（Puck）& 林醫師（Leda） 討論主題： 1. THN3：pHGNS 三年追蹤結果 — Chest 2026 2. OSA手術門診心血管健康 — Laryngoscope 2026 3. HGNS 反應預測 — JAMA Otolaryngol 2026 4. 形態量測取代DISE — OTO Open 2026 5. 頭頸癌存活者OSA盛行率83.7% 6. 睡眠外科與全身健康 7. GLP-1 RA 與睡眠外科 修復版：正確outro時間點、無尾音雜音

  30. 43

    Episode 45-Special | 2026/05/23

    ENT Update Podcast 特輯 - 2026/05/23（週六：人工智慧在耳鼻喉科應用）修復版 主持人：傅醫師（Puck）& 林醫師（Leda） 討論主題： 1. ChatGPT-5 vs ENT主治醫師 — Egyptian J Otolaryngol 2. Emory AI 語音喉癌檢測 — 93%準確率 3. Flinders Multimodal AI 中耳炎診斷 4. ML預測頭頸癌ENE — Laryngoscope 5. AI Chasm分析 — Nature npj Digital Medicine 6. Lightweight DL鼻息肉分類 — Edge computing 7. Stanford 睡眠AI穿戴裝置 修復：修正outro時間點、消除尾音雜音

  31. 42

    Episode 44 | 2026/05/22

    ENT Update, Episode 44 | 2026/05/22. ENT Head and Neck Medicine latest information.

  32. 41

    Episode 43-Special | 2026/05/21

    ENT Update, Episode 43-Special | 2026/05/21. ENT Head and Neck Medicine latest information.

  33. 40

    Episode 42 | 2026/05/20

    ENT Update, Episode 42 | 2026/05/20. ENT Head and Neck Medicine latest information.

  34. 39

    Episode 41 | 2026/05/20

    ENT Update, Episode 41 | 2026/05/20. ENT Head and Neck Medicine latest information.

  35. 38

    Episode 40 | 2026/05/21

    ENT Update Podcast - 2026/05/21 (週四：睡眠醫學專題) 討論主題：睡眠呼吸中止症最新治療選擇 重點整理： 1. AD109 口服藥 Phase 3 SynAIRgy 成功 — AHI下降55.6%，已送FDA (AJRCCM, May 18 2026) 2. Zepbound (tirzepatide) 首個FDA核准用於肥胖型OSA藥物 3. Inspire V 雙側舌下神經刺激器 — 新一代植入裝置 4. Barbed Suture Pharyngoplasty — 倒刺縫線咽喉整形術 5. Solriamfetol — 改善OSA白天嗜睡 製作：洪士涵醫師

  36. 37

    Episode 39 | 2026/05/20

    ENT Update, Episode 39 | 2026/05/20. ENT Head and Neck Medicine latest information.

  37. 36

    Episode 38 | 2026/05/19

    ENT Update Podcast - 2026/05/19 (週二：耳科與聽力學專題) 討論文獻： 1. Otarmeni(lunsotogene parvec) FDA Accelerated Approval - First gene therapy for OTOF hearing loss (Apr 23, 2026) 2. Envoy Medical Acclaim Fully Implanted CI - 56 patients activated (Apr 2026) 3. Osia 2 System Audiological Outcomes - Otol Neurotol (Mar 1, 2026) 4. Polygenic SNHL GWAS - Million Veteran Program, JARO (Mar 16, 2026)

  38. 35

    Episode 37 | 2026/05/18

    本期 ENT Update Podcast（2026/5/18 週一）探討頭頸外科與腫瘤學專題。主持人傅醫師與林醫師辯證式討論以下文獻： KEYNOTE-689 — 圍手術期 Pembrolizumab 用於局部晚期頭頸癌 - NEJM 2025; DOI: 10.1056/NEJMoa2501065 - FDA 已核准用可切除局部晚期 HNSCC 圍手術期治療 NIVOPOSTOP (GORTEC 2018-01) — 輔助性 Nivolumab 用於高風險頭頸癌 - Lancet 2026; DOI: 10.1016/S0140-6736(25)02713-7 - 3年無疾病存活率 63.1% vs 52.5%（HR 0.76） TORS 長期腫瘤學預後 — HPV 陽性口咽癌五年存活率接近 90% - Otolaryngol Head Neck Surg 2026 TORS 單一治療吞嚥功能長期追蹤 - Head & Neck 2026 SEOM-TTCC 2025 頭頸癌治療指引更新 - Clin Transl Oncol 2026 CSCO 2026 頭頸部腫瘤診療指南

  39. 34

    Episode 36-Special | 2026/05/18

    ENT Update 2026-05-18 頭頸部腫瘤特輯 參考文獻: 1. Lactylation-driven metabolic-immune crosstalk: CD44, APP causal risk genes in HNSCC. Front Immunol, 15 May 2026. DOI: 10.3389/fimmu.2026.xxxxx 2. Neural-derived CCL5-Treg-RAMP1 axis: perineural invasion causes immunosuppression. J Immunother Cancer, 8 May 2026. DOI: 10.1136/jitc-2026.xxxxx 3. EGFR/Cyclin D1/Bcl-2 high expression prognostic meta-analysis. OTO Open, 14 Apr 2026. DOI: 10.1002/oto2.xxxxx 4. LEAP-010: Pembro+Lenvatinib improves PFS but not OS in R/M HNSCC. JCO, Mar 2026. DOI: 10.1200/JCO.2026.xxxxx 5. PNI predicts poor Pembrolizumab efficacy. Laryngoscope, Jan 2026. DOI: 10.1002/lary.xxxxx 6. SLC16A1/MCT1-STAT3-SLC7A11 ferroptosis axis. Oncol Res, 2026. DOI: 10.32604/or.2026.xxxxx 7. Future of systemic therapy for R/M HNSCC: bispecific Abs & HPV vaccines. Front Oncol, 26 Mar 2026. DOI: 10.3389/fonc.2026.xxxxx 8. Personalized medicine: ctDNA de-escalation, risk-adapted CRT. Front Oncol, 15 May 2026. DOI: 10.3389/fonc.2026.xxxxx 9. Anterior skull base ACC: GTR + proton therapy optimal. Eur J Cancer, May 2026. DOI: 10.1016/j.ejca.2026.xxxxx 10. PROMs quality of life clinical application. Qual Life Res, May 2026. DOI: 10.1007/s11136-026-xxxxx

  40. 33

    Episode 35 | 2026/05/17

    ENT Update Podcast - 2026年5月17日 (一週專題回顧) 參考文獻： 1. SEOM-TTCC HNC guidelines. Clin Transl Oncol. 2026 Mar 17. 2. NIVOPOST-OP. Lancet. 2026 Jan 24. 3. Neoadjuvant chemoimmunotherapy HNC. PMID: 41842604 4. CI in Asymmetric Hearing Loss. Otol Neurotol. 2026 Mar. 5. Biologics CRSwNP. PMID: 41518424 6. THN3 pHGNS 3yr. Chest 2026 May. DOI: 10.1016/j.chest.2025.11.057 7. OSPREY pHGNS. Annals Intern Med. 2026 Apr 20. 8. Hydrogel vocal cord. Biomaterials. McGill. 2026. 9. OBIL UVFP. PMID: 41353483 10. AI CADx Laryngoscopy. OTO HNS. 2026 Feb. DOI: 10.1002/ohn.70153 11. DL scoping OHNS. Nature Digital Med. 2025. 12. DL model ENT. Sci Rep. 2026 Feb 10.

  41. 32

    Episode 34-Special | 2026/05/16

    睡眠外科特輯｜PPPP｜OSA+LPR｜舌骨懸吊｜pHGNS 3年｜HNS分期｜OSPREY｜機器人舌根｜術前篩檢｜唐氏症兒童｜ENT Update Podcast

  42. 31

    Episode 33 | 2026/05/16

    ENT Update Podcast - 2026/05/16 主題：人工智慧在耳鼻喉科應用 本集討論文獻： 1. Integration of AI into ENT practice: comparative study Egypt J Otolaryngol (2026 Mar 23) DOI: 10.1186/s43163-026-01055-x URL: https://link.springer.com/article/10.1186/s43163-026-01055-x 2. Generative AI in otolaryngology (Kowalski et al.) Otorhinolaryngol 2026;76(1):23-35 DOI: 10.23736/S2724-6302.26.02601-0 3. ML prediction of eosinophilic CRSwNP PMID: 41847830 (2026 Mar 18) URL: https://pubmed.ncbi.nlm.nih.gov/41847830/

  43. 30

    Episode 32 | 2026/05/15

    ENT Update Podcast - 2026/05/15 - 喉科學與聲音醫學 References: 1. AAO-HNS/ASHA Consensus Statement on the Use of Voice Therapy in the Treatment of Dysphonia (2026 Mar 3). https://www.entnet.org/resource/consensus-statement-on-the-use-of-voice-therapy-in-the-treatment-of-dysphonia/ 2. Treatment Efficacy for Functional Voice Disorders with Dysphonia: A Network Meta-analysis. Journal of Voice (2026 Mar 3). https://www.sciencedirect.com/science/article/pii/S0892199726000676 3. Intralesional Steroid Injection vs Voice Therapy for Early Vocal Fold Nodules: An RCT. European Archives of Oto-Rhino-Laryngology (2025 Dec 29). https://link.springer.com/article/10.1007/s00405-025-09923-7 4. Outcomes of Voice Therapy in Organic Voice Disorders: A Scoping Review. Journal of Voice (2026 May 5). https://www.sciencedirect.com/science/article/pii/S0892199726001335 5. Long-Term Retention of Voice Therapy Outcomes After Discharge. Journal of Voice (2025 Dec 18). PubMed: 41419425 6. Clinical Applications of Laryngeal Ultrasonography: A Review. Journal of Voice (2025 Oct 29). PubMed: 41168021 7. Family-Involved Hybrid Voice Therapy for Pediatric VF Nodules. Laryngoscope Investigative Otolaryngology (2026 Apr 30). https://onlinelibrary.wiley.com/doi/full/10.1002/lio2.70422 8. Barriers and Readiness to Voice Therapy Among School Teachers. Journal of Voice (2025 Jul 29).

  44. 29

    Episode 31 | 2026/05/14

    ENT Update Podcast - 2026年5月14日 (週四) 主題：睡眠醫學 本集參考文獻： 1. Tirzepatide on OSA-related cardiometabolic risk: SURMOUNT-OSA secondary analysis Nature Medicine, January 2026 DOI: 10.1038/s41591-025-04071-1 https://www.nature.com/articles/s41591-025-04071-1 2. Proximal hypoglossal nerve stimulation for OSA: A randomized controlled trial The Lancet Respiratory Medicine, April 2026 https://medicalxpress.com/news/2026-04-implanted-nerve-obstructive-apnea-safe.html 3. SleepFM: AI model predicts disease risk from sleep data Nature Medicine / Stanford Medicine, January 2026 https://med.stanford.edu/news/all-news/2026/01/ai-sleep-disease.html 4. Mayo Clinic AI-enabled ECG analysis for OSA detection AASM Key Trends in Sleep Medicine Q1 2026 https://aasm.org/key-trends-in-sleep-medicine-q1-2026/ 5. Growth and sleep outcomes after adenotonsillectomy in pediatric OSA Scientific Reports, December 2025 DOI: 10.1038/s41598-025-30271-3 https://www.nature.com/articles/s41598-025-30271-3 6. Long-term Health Outcomes of Pediatric OSA Sleep Medicine, May 2026 https://www.sciencedirect.com/science/article/abs/pii/S1389945726002480 7. Pediatric DISE-directed surgery outcomes in OSA Otolaryngology-Head and Neck Surgery, February 2026 DOI: 10.1002/ohn.70166 https://aao-hnsfjournals.onlinelibrary.wiley.com/doi/10.1002/ohn.70166 主持人：傅醫師 (zh-TW-YunJheNeural) 與 林醫師 (zh-TW-HsiaoChenNeural) 語速：+12%

  45. 28

    Episode 30 | 2026/05/13

    ENT Update Podcast - 2026/05/13 (週三) 主題：鼻科學 (Rhinology) 參考文獻： 1. EVEREST Trial: Dupilumab vs Omalizumab in CRSwNP Lancet Respir Med 2025 Sep. DOI: 10.1016/S2213-2600(25)00287-5 Ann Intern Med 2026 Feb. DOI: 10.7326/ANNALS-25-05457-JC PMID: 41628459 2. ESS vs Biologic Therapy for CRSwNP: Systematic Review Rhinology 2026. PMID: 41487053 3. Contemporary Office-Based Procedures in Rhinology Front Allergy 2025 Jul. DOI: 10.3389/falgy.2025.1554792 PMID: 40756135 4. Biologics for CRSwNP: Advances in Therapy Front Allergy 2026. DOI: 10.3389/falgy.2026.1759649 5. Tezepelumab for Olfaction in CRSwNP PubMed 2026 Jan. PMID: 41493192 6. Balloon Sinuplasty vs ESS Meta-Analysis JORR 2025 Jun. 主持：傅醫師 (男聲) & 林醫師 (女聲)

  46. 27

    Episode 29 | 2026/05/12

    本集主題：耳科與聽力學專題 (2026/05/12) 參考文獻： 1. FDA Approval of Otarmeni (lunsotogene parvec-cwha) - First gene therapy for OTOF-related hearing loss FDA Press Release: https://www.fda.gov/news-events/press-announcements/fda-approves-first-ever-gene-therapy-treatment-genetic-hearing-loss-under-national-priority-voucher CNN Report: https://edition.cnn.com/2026/04/23/health/fda-gene-therapy-inherited-deafness-regeneron Harvard Medicine: https://hms.harvard.edu/news/hearing-restoration-gene-therapy-inherited-deafness-lasts-years-new-trial-results-show 2. Gene Therapy vs Cochlear Implants - Direct Comparison Mass General Advances: https://advances.massgeneral.org/otolaryngology/article.aspx?id=1616 3. Robotic-Assisted Electrode Array Insertion Improves Stability of Acoustic Hearing Thresholds Khan UA et al. Laryngoscope. 2026 Jan 21. DOI: 10.1002/lary.70380 | PMID: 41562332 4. Hearing loss in the young-old is associated with increased risk for Alzheimer's disease and vascular dementia Francis L et al. J Alzheimers Dis. 2026 Feb;109(3):1142-1148. DOI: 10.1177/13872877251407211 | PMID: 41555782 | PMCID: PMC12855611 5. International expert consensus on gene therapy for hereditary hearing loss PMID: 41135524 主持人：傅醫師（男聲）、林醫師（女聲） 製作日期：2026-05-12 片長：約7分18秒

  47. 26

    Episode 1 | 2026/04/23

    ENT Update 創刊號 — 耳鼻喉頭頸外科最新文獻回顧 (2026/04/23) 本集為ENT Update 首集，介紹近期頭頸部腫瘤與耳科學重要文獻，包含頭頸癌手術治療新進展及耳科疾病診斷技術更新。 主持人：傅醫師（引導）、林醫師（批判辯證） ENT Update - 每週專業耳鼻喉頭頸外科深度對談

  48. 25

    Episode 4 | 2026/04/26

    ENT Update — 最新研究回顧 (2026/04/26) 本集討論近期耳鼻喉科重要文獻，涵蓋頭頸腫瘤治療策略、鼻科學新知與睡眠醫學進展。 主持人：傅醫師（引導）、林醫師（批判辯證） ENT Update - 每週專業耳鼻喉頭頸外科深度對談

  49. 24

    Episode 5 | 2026/04/27

    ENT Update — 最新研究回顧 (2026/04/27) 本集討論頭頸部腫瘤治療最新進展與臨床實證，涵蓋免疫治療、標靶治療及多專科團隊治療策略。 主持人：傅醫師（引導）、林醫師（批判辯證） ENT Update - 每週專業耳鼻喉頭頸外科深度對談

  50. 23

    Episode 10 | 2026/05/01

    ENT Update — 喉科學與聲音醫學專題 (2026/05/01) 本集探討喉科學與聲音醫學最新進展： 主題一：嗓音治療用於功能性嗓音疾患之網絡統合分析 主題二：聲樂健康習慣認知差異研究 主題三：聲帶腫塊非手術 vs 手術治療成效比較 主持人：傅醫師（引導）、林醫師（批判辯證） ENT Update - 每週專業耳鼻喉頭頸外科深度對談

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ABOUT THIS SHOW

Ear, nose and throat head and neck medicine latest information. Weekly curated international literature, research progress and clinical updates for medical professionals. Content includes: otology, rhinology, laryngology, head and neck surgery, speech therapy, audiology, etc.

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洪士涵醫師

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Ear, nose and throat head and neck medicine latest information. Weekly curated international literature, research progress and clinical updates for medical professionals. Content includes: otology, rhinology, laryngology, head and neck surgery, speech therapy, audiology, etc.

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