Gastrointestinal Cancer Update

Featuring perspectives from Ms Caroline Kuhlman, Dr Eileen M O'Reilly, Dr Philip A Philip and Ms Amanda K Wagner, moderated by Dr O'Reilly, including the following topics:Introduction (0:00)Clinical Presentation and Prognosis of Pancreatic Adenocarcinoma (PAD) (3:29)Recent Advances in Up-Front Treatment for Metastatic PAD (15:47)Selection and Sequencing of Therapy for Relapsed/Refractory Metastatic PAD (39:58)Novel Strategies Targeting RAS Mutations in Advanced PAD (48:20)Utility of Tumor Treating Fields in PAD Management (1:13:58)CME information and select publications

Featuring perspectives from Dr David H Ilson and Dr Kohei Shitara, including the following topics:Introduction (0:00)Biomarker Evaluation in Localized and Metastatic Disease (1:49)Role of Immune Checkpoint Inhibitors in the Management of Gastroesophageal Cancers — Dr Ilson (7:37)Other Available Therapeutic Approaches — Dr Shitara (33:22)CME information and select publications

Featuring perspectives from Dr Yelena Y Janjigian, Dr Manish A Shah and Prof Eric Van Cutsem, moderated by Dr Janjigian, including the following topics:Introduction (0:00)HER2-Targeted Approaches in Advanced Gastroesophageal Cancers — Prof Van Cutsem (2:08)Targeting CLDN18.2 in Advanced Gastroesophageal Cancers — Dr Shah (30:54)Available Immunotherapeutic Strategies for Advanced Gastroesophageal Cancers — Dr Janjigian (1:01:39)CME information and select publications

Featuring perspectives from Dr Tanios Bekaii-Saab, Dr Stacey A Cohen and Dr Arvind Dasari, moderated by Dr Bekaii-Saab, including the following topics:Introduction (0:00)Current and Future Role of Immune Checkpoint Inhibition in the Management of Microsatellite Instability-High/Mismatch Repair Deficient Localized and Locally Advanced Colorectal Cancer (CRC) — Dr Cohen (1:45)Clinical Relevance and Practical Utilization of Molecular Residual Disease Analysis in CRC — Dr Dasari (34:08)Recent Advances in Metastatic CRC: Optimizing Immunotherapy and Other Approaches — Dr Bekaii-Saab (1:00:42)CME information and select publications

Featuring perspectives from Dr Kristen K Ciombor and Dr John Strickler, including the following topics:Introduction (0:00)Current and Future Role of Immune Checkpoint Inhibitors in the Management of Colorectal Cancer (CRC) — Dr Ciombor (3:58)Other Recent Advances in CRC Management — Dr Strickler (32:57)CME information and select publications

Featuring an interview with Prof Bernd Kasper, including the following topics:Case: A woman in her early 30s develops a progressing desmoid tumor in her abdomen during pregnancy(0:00)Case: A woman in her late 30s with a painful small desmoid tumor in her rectus abdominus undergoes cryoablation (8:04)Case: A woman in her late teens with recurrent desmoid tumors in her right thigh undergoes multiple resections (13:58)Case: A woman in her mid 70s has a desmoid tumor causing erosion in her scapular region (17:19)CME information and select publications

Featuring perspectives from Dr Yelena Y Janjigian and Dr Samuel J Klempner, including the following topics:Introduction (0:00)Role of Anti-PD-1/PD-L1- and CLDN18.2-Directed Antibodies in the Management of Gastroesophageal Cancers — Dr Klempner (5:52)Management of HER2-Positive Gastroesophageal Cancers — Dr Janjigian (28:20)CME information and select publications

Featuring perspectives from Dr Eileen M O’Reilly and Dr Philip A Philip, including the following topics: Introduction (0:00)Optimal Incorporation of Chemotherapy into the Management of Advanced Pancreatic Cancer — Dr Philip (7:27)Other Available and Emerging Novel Approaches for Pancreatic Cancer — Dr O’Reilly (28:05)CME information and select publications

Prof Bernd Kasper from the Mannheim Cancer Center in Mannheim, Germany, discusses recent updates on available and novel treatment strategies for desmoid tumors.CME information and select publications here.

Dr Arvind Dasari from the University of Texas MD Anderson Cancer Center in Houston and Dr Anwaar Saeed from UPMC Hillman Cancer Center in Pittsburgh, Pennsylvania, discuss key clinical trial data regarding the management of colorectal cancer.CME information and select publications here.

Dr Jaffer A Ajani from The University of Texas MD Anderson Cancer Center in Houston, Dr Rutika Mehta from Weill Cornell Medicine in New York, New York, Dr John Strickler from Duke University in Durham, North Carolina, and moderator Dr Samuel J Klempner from Massachusetts General Hospital in Boston review data supporting immunotherapy for gastroesophageal cancers and findings presented at the 2026 ASCO Gastrointestinal Cancers Symposium.CME information and select publications here.

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer. CME information and select publications here.