PODCAST · health
Gut Podcast
by BMJ Group
The Gut Podcast is your go-to source for the latest discussions in gastroenterology and hepatology. Each month Dr. Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, dives into key issues in the field by discussing articles with their authors.Gut - gut.bmj.com - is an international journal from BMJ Group and the British Society of Gastroenterology (BSG) publishing research and review articles in gastroenterology and hepatology.Stay up to date with the latest research in gastroenterology. Subscribe to the Gut podcast.* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Li
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129
Eosinophilic oesophagitis: the therapeutic potential of FOXM1 inhibition
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Amanda Muir from the Department of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, and University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA, on the paper "FOXM1 inhibition reduces IL-13-induced epithelial remodelling and inflammation in eosinophilic oesophagitis" published in paper copy in Gut in May 2026. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://bit.ly/4rRJeUI).
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128
Long-term prognosis of lean MASLD: evidence from three population-based prospective cohorts
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Shanshan Wu from the Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Disease, Beijing, China, and Professor Yuanjie Pang from Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China, on the paper "Long-term prognosis of lean MASLD: evidence from three population-based prospective cohorts" published in paper copy in Gut in April 2026. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://bit.ly/4rRJeUI).
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127
Managing type 2 diabetes patients with MASLD
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Xiaolong Qi from Centre of Liver Disease, Zhongda Hospital, Southeast University, Nanjing, China on the paper "Two-step clinical care pathway to predict MASLD-related advanced fibrosis and long-term outcomes in type 2 diabetes" published in paper copy in Gut in March 2026. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://bit.ly/4rRJeUI).
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126
Targeting MASLD with new nanoparticles
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Zhi-Gang She from the State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Gannan Innovation and Translational Medicine Research Institute; School of Pharmacy; First Affiliated Hospital, Gannan Medical University, Ganzhou, China. Professor She is also the Deputy Director of the Department of Cardiology, Renmin Hospital of Wuhan University. Professor She is interviewed on the paper "Discovery of a carboxyl fullerene derivative as a new lipid droplet regulator inhibiting MASLD" published in paper copy in Gut in February 2026. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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125
Performance of the China-CLIF framework in acute-on-chronic liver failure
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Jun Li from the State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China on the paper "Performance of the China-CLIF framework in acute-on-chronic liver failure: a multicohort study across all aetiologies" published in paper copy in Gut in January 2026. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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124
Predicting short-term liver transplant outcomes with graft microbial DNA signature
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Fernando Lucas-Ruiz from the Biomedical Research Institute of Murcia, Murcia, Spain on the paper "Intrahepatic donor microbiota-based metataxonomic signature detected in organ preservation solution enables prediction of short-term liver transplant outcomes" published in paper copy in Gut in December 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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123
Screening and eradication of H pylori for gastric cancer prevention: Taipei Global Consensus II
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Jyh-Ming Liou from Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan on the paper "Screening and eradication of Helicobacter pylori for gastric cancer prevention: Taipei Global Consensus II" published in paper copy in Gut in November 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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122
Helicobacter pylori antibiotic resistance: a global challenge in search of solutions
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Christian Schulz from the Medical Department 2, LMU Munich, Munich, Germany on the paper "Helicobacter pylori antibiotic resistance: a global challenge in search of solutions" published in paper copy in Gut in October 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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121
Effective treatment of severe acute pancreatitis using COX-2 inhibitors
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Chengwei Tang and Associate Professor Zhiyin Huang from the Department of Gastroenterology, West China Hospital of Sichuan University, Chengdu, Sichuan, China on the paper "Parecoxib sequential with imrecoxib for occurrence and remission of severe acute pancreatitis: a multicentre, double-blind, randomised, placebo-controlled trial" published in paper copy in Gut in September 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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120
Protecting against Crohn's disease with dietary whey protein
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Tao Zuo from the Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, Guangdong, China, on the paper "Dietary whey protein protects against Crohn’s disease by orchestrating cross-kingdom interaction between the gut phageome and bacteriome" published in paper copy in Gut in August 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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119
Comparing diclofenac and indomethacin for prevention of post-ERCP pancreatitis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Yanglin Pan from the State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China, on the paper "Rectal diclofenac versus indomethacin for prevention of post-ERCP pancreatitis (DIPPP): a multicentre, double-blind, randomised, controlled trial" published in paper copy in Gut in July 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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118
Studying oat ingestion in coeliac disease with purified oat protein
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Tye-Din from the Immunology Division, Walter and Eliza Hall Institute of Medical Research, and Department of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia, on the paper "Purified oat protein can trigger acute symptoms linked to immune activation in coeliac disease patients but not histological deterioration" published in paper copy in Gut in June 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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117
Predicting sensitivity to dietary emulsifiers using an in-vitro microbiota model
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Benoit Chassaing and Dr Héloïse Rytter from Microbiome-Host Interactions, INSERM, Institut Pasteur, Université Paris Cité, Paris, France, on the paper "In vitro microbiota model recapitulates and predicts individualised sensitivity to dietary emulsifier" published in paper copy in Gut in May 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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116
Antiviral treatment of chronic Hepatitis B
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Yao-Chun (Holden) Hsu from School of Medicine and Graduate Institute of Medicine, I-Shou University, Kaohsiung, Taiwan, on the paper "Effects of tenofovir disoproxil fumarate on intrahepatic viral burden and liver immune microenvironment in patients with chronic hepatitis B" published in paper copy in Gut in April 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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115
Single-cell spatial profiling of immunotypes in hepatocellular carcinoma
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Bertram Bengsch and Dr Henrike Salie from the Department of Internal Medicine II, Medical Centre, University of Freiburg, Freiburg, Germany, on the paper "Spatial single-cell profiling and neighbourhood analysis reveal the determinants of immune architecture connected to checkpoint inhibitor therapy outcome in hepatocellular carcinoma" published in paper copy in Gut in March 2025.
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114
Understanding the gut-adipose-liver axis and its impact on insulin action
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Jordi Mayneris-Perxachs and Dr Anna Castells-Nobau from the Girona Biomedical Research Centre (IDIBGI), Girona, Spain, on the paper "Multiomics of the intestine-liver-adipose axis in multiple studies unveils a consistent link of the gut microbiota and the antiviral response with systemic glucose metabolism" published in paper copy in Gut in February 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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113
Linking breastfeeding and atopic dermatitis in infants
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Suhua Jiang from the Department of Paediatrics, The First People's Hospital of Foshan, Foshan, People's Republic of China and Professor Lin Zhang, Assistant Professor from Department of Anaesthesia and Intensive Care and Lead Scientist, Microbiota I-Center (MagIC) in the Chinese University of Hong Kong, on the paper "Association of breast milk-derived arachidonic acid-induced infant gut dysbiosis with the onset of atopic dermatitis" published in paper copy in Gut in January 2025. A close transcript of this podcast is available at this link: https://bit.ly/40jF5xo Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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112
Improving CLDN18.2 BiTEs efficacy against pancreatic cancer
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Professor Jihui Hao from the Department of Pancreatic Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, on the paper "CD64+ fibroblast-targeted vilanterol and a STING agonist augment CLDN18.2 BiTEs efficacy against pancreatic cancer by reducing desmoplasia and enriching stem-like CD8+ T cells" published in paper copy in Gut in December 2024. A close transcript of this podcast is available at this link: https://bit.ly/3Ox8Io2 Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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111
Gut microbiota signatures of vulnerability to food addiction in mice and humans
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Elena Martín-García and Professor Rafael Maldonado from the Laboratory of Neuropharmacology, Pompeu Fabra University and Hospital del Mar Research Institute, Barcelona, Spain and Professor Jose Manuel Fernández-Real from the Endocrinology, Nutrition, Eumetabolism & Health group, Hospital Trueta of Girona, University of Girona, Girona, Spain on the paper "Gut microbiota signatures of vulnerability to food addiction in mice and humans" published in paper copy in Gut in November 2024. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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110
Gastric intestinal metaplasia: reviewing current guidelines
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Mario Dinis-Ribeiro from the Department of Gastroenterology at Porto Comprehensive Cancer Center & RISE—Health Research Network, Porto, Portugal, on the paper "The road to a world-unified approach to the management of patients with gastric intestinal metaplasia: a review of current guidelines" published in paper copy in Gut in October 2024. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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109
Exploring stem cell therapy for Hirschsprung disease
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Conor McCann from the Department of Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, London, UK and Dr Anestis Tsakiridis from the School of Biosciences, The University of Sheffield, Sheffield, UK on the paper "Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue" published in paper copy in Gut in September 2024. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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108
Protective function of sclerosing cholangitis on IBD
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Samuel Huber, from the Department of Medicine, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany, on the paper "Protective function of sclerosing cholangitis on IBD" published in paper copy in Gut in August 2024. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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107
Linking high-fat diet and liver tumorigenesis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Jianping Guo from Institute of Precision Medicine, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China, on the paper "High-fat diet promotes liver tumorigenesis via palmitoylation and activation of AKT" published in paper copy in Gut in July 2024. A close transcript of this podcast is available at this link: https://bit.ly/3zlcoVF Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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106
Hepatocellular carcinoma in patients with liver cirrhosis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Hashem El-Serag from the Department of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA, on the paper "Serum biomarker signature is predictive of the risk of hepatocellular cancer in patients with cirrhosis" published in paper copy in Gut in June 2024. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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105
Microbiome interventions for COPD protection
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Kurtis Budden, from the Immune Health Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia and Professor Philip Hansbro who is also a conjoint there and the Director of the Centenary Institute and University of Technology Sydney Centre for Inflammation, Sydney, NSW, Australia, on the paper "Faecal microbial transfer and complex carbohydrates mediate protection against COPD" published in paper copy in Gut in May 2024. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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104
MASLD: a systemic metabolic disorder with cardiovascular and malignant complications
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Herbert Tilg who is the Head of Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology & Metabolism, Medical University of Innsbruck, Innsbruck, Austria on on the Recent Advances in Clinical Practice paper "MASLD: a systemic metabolic disorder with cardiovascular and malignant complications" published in paper copy in Gut in April 2024. Read the paper: https://gut.bmj.com/content/73/4/691 Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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103
RE.GA.IN: the Real-world Gastritis Initiative
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Massimo Rugge who is a Honorary Professor of Pathology at the Padova University and Adjunct Professor of Medicine and Gastroenterology at the Baylor College of Medicine in Houston; Professor Peter Malfertheiner who is senior Professor of Medicine at the Ludwig Maximilian University of Munich, Munich, Germany and Professor Robert Genta who is an Adjunct Professor of Pathology and Medicine (Gastroenterology) at Baylor College of Medicine, Houston, Texas, as well as the Chief for Academic Affairs at Fulgent-Inform Diagnostics in Irving, Texas. They are interviewed on the paper "RE.GA.IN.: the Real-world Gastritis Initiative-updating the updates " published in paper copy in Gut in March 2024. Read the paper: https://bit.ly/3IgUggW Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).
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102
Prebiotic diet changes neural correlates of food decision-making in overweight adults
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Veronica Witte from the Department of Cognitive Neurology, University of Leipzig Medical Center, Leipzig, Germany, on the paper "Prebiotic diet changes neural correlates of food decision-making in overweight adults: a randomised controlled within-subject cross-over trial" published in paper copy in Gut in February 2024 and available online - https://gut.bmj.com/content/73/2/298 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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101
Lethal sepsis prevention with novel tripeptide RKH derived from Akkermansia muciniphila
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Professor Peng Chen, from the Department of Pathophysiology, Southern Medical University, Guangzhou, China, on the paper "Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis" published in paper copy in Gut in January 2024. Read the paper included in the January 2024 issue: https://gut.bmj.com/content/73/1/78 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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100
Special Gut Podcast: Digestive health and climate change
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews a fantastic panel of guests from around the globe including: Professor Bishr Omary from Rutgers University, Piscataway, New Jersey, USA who was the past president of the American Gastroenterological Association Professor Desmond Leddin from Dalhousie University, Halifax, Nova Scotia, Canada and incoming chair of the World Gastroenterology Organization (WGO) climate change and sustainability committee Professor Geoffrey Metz from The University of Melbourne and Monash University, Melbourne, Victoria, Australia and president-elect of the WGO Professor Andrew Veitch from the Department of Gastroenterology, New Cross Hospital, Wolverhampton, UK and president of the British Society of Gastroenterology Professor Guilherme Macedo from the Department of Gastroenterology, Centro Hospitalar de São João, Porto, Portugal and president of the WGO Associate Professor Mai Ling Perman from Fiji National University, Suva, Fiji and the Head of School of Medical Science They are interviewed regarding an exciting 9-commentary series related to digestive health and climate change which is being published in GUT in December 2023. Each commentary summarizes one, or a hybrid, of the nine educational webinars organised by the World Gastroenterology Organisation (WGO). This concise podcast is unusual in that it has the 6 participants who were involved in setting up the WGO webinar course and the commentaries that were developed from this course, and that it highlights an entire commentary series on a very important topic that GUT is very proud to publish. Please read the commentary series here: https://gut.bmj.com/content/72/12/2193 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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99
Gastrointestinal origins for Parkinson’s disease
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Jay Pasricha, Chair of the Department of Medicine, Mayo Clinic Arizona, Arizona, USA and Bo Konings, final year medical student and researcher at the Translational Research Centre for Gastrointestinal Disorders (TARGID), KU Leuven University Hospitals, Leuven, Belgium, on the paper "Gastrointestinal syndromes preceding a diagnosis of Parkinson’s disease: testing Braak’s hypothesis using a nationwide database for comparison with Alzheimer’s disease and cerebrovascular diseases" published in paper copy in Gut in November 2023 and available online: https://gut.bmj.com/content/72/11/2103 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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98
Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Julia Mayerle and Dr Simon Sirtl from the Department of Medicine II, LMU University Hospital, Munich, Germany, on the paper "Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis" published in paper copy in Gut in October 2023 and available online: https://gut.bmj.com/content/72/10/1919 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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97
Rome consensus on gut microbiota and faecal microbiota transplantation in IBD
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Loris Lopetuso, Department of Medicine and Ageing Sciences, University of Chieti-Pescara, Italy, on the paper "The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease", published in paper copy in Gut in September 2023, and available online: https://gut.bmj.com/content/72/9/1642 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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96
The therapeutic potential of fasting
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Thomas Marjot, Hepatology SpR from the Oxford Liver Unit in Oxford University Hospitals and also a Wellcome Trust Clinical Research Training Fellow at the University of Oxford based at the Oxford Centre for Diabetes, Endocrinology and Metabolism, UK, on the paper "Timing of energy intake and the therapeutic potential of intermittent fasting and time-restricted eating in NAFLD" published in paper copy in Gut in August 2023 and available online: https://gut.bmj.com/content/72/8/1607 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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95
Helicobacter pylori promotes colorectal carcinogenesis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Markus Gerhard from the Institute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich, Germany, on the paper "Helicobacter pylori promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature" published in paper copy in Gut in July 2023 and available online: https://gut.bmj.com/content/72/7/1258 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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94
Single-cell transcriptomics sheds new light on pancreas biology and disease
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Kathy DelGiorno, from the Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA, on the paper 'It is better to light a candle than to curse the darkness: single-cell transcriptomics sheds new light on pancreas biology and disease' published in paper copy in Gut in June 2023 and available online: https://gut.bmj.com/content/72/6/1211 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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93
Counteracting the harm of dietary emulsifiers with Akkermansia muciniphila
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Benoit Chassaing, group leader from the “Mucosal microbiota in chronic inflammatory diseases” Team at INSERM and the Université Paris Cité, Paris, France, on the paper 'Akkermansia muciniphila counteracts the deleterious effects of dietary emulsifiers on microbiota and host metabolism' published in paper copy in Gut in May 2023 and available online: https://gut.bmj.com/content/72/5/906 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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92
Antibiotic use as a risk factor for IBD
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Tine Jess, from the Center for Molecular Prediction of Inflammatory Bowel Disease, Department of Clinical Medicine, and Department of Gastroenterology and Hepatology, Aalborg University, Aalborg, Denmark, and Dr Adam S Faye, from the Department of Medicine and Population Health, New York University Langone Health, New York, USA, on the paper 'Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study' published in paper copy in Gut in April 2023 and published online: https://gut.bmj.com/content/72/4/663 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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91
Predicting disease progression in bridging fibrosis and cirrhosis with liver stiffness
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Rohit Loomba, Professor of Medicine in the Division of Gastroenterology, and Adjunct Professor in the Division of Epidemiology at the University of California San Diego, La Jolla, California, USA on the paper 'Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis and cirrhosis' published in paper copy in Gut in March 2023 and available online: https://gut.bmj.com/content/72/3/581 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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90
Assessing the impact of dietary fibre on bile acid transformation by gut bacteria in mice
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Fredrik Bäckhed, The Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden on the paper '6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice' published in paper copy in Gut in February 2023, and available online: https://gut.bmj.com/content/72/2/314 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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89
Autoimmune gastritis: cancer risk in consistently tested H. pylori-negative patients
Dr Philip Smith, Digital and Education Editor of Gut, and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Professor Massimo Rugge, Pathologist at Padova University, Italy, and Adjunct Professor of Medicine at the Baylor College of Medicine in Houston, Texas, USA; and Ms Ludovica Bricca, a student at Padova University, and the youngest researcher involved in the study. They are interviewed on the paper 'Autoimmune gastritis: long-term natural history in naïve Helicobacter pylori-negative patients' published in paper copy in Gut in January 2023. Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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88
FMT-AID trial shows effectiveness in inducing remission of ulcerative colitis
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Vineet Ahuja who is from the Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India, on the paper 'Faecal microbiota transplantation with anti-inflammatory diet (FMT-AID) followed by anti-inflammatory diet alone is effective in inducing and maintaining remission over 1 year in mild to moderate ulcerative colitis: a randomised controlled trial' published in paper copy in Gut in December 2022 and available online: https://gut.bmj.com/content/71/12/2401 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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87
Endoscopic pyloromyotomy for the treatment of severe and refractory gastroparesis
Endoscopic pyloromyotomy (G-POEM) is a minimally invasive treatment option with promising uncontrolled outcome results in patients with gastroparesis. Dr Philip Smith, Digital and Education Editor of Gut, interviews Professor Jan Martinek, from the Department of Hepatogastroenterology, Institute of Clinical and Experimental Medicine, Prague, Czech Republic, about his paper on this topic. The article titled 'Endoscopic pyloromyotomy for the treatment of severe and refractory gastroparesis: a pilot, randomised, sham-controlled trial' is published in paper copy in Gut in November 2022 and available online at: https://gut.bmj.com/content/71/11/2170 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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86
Climate change: a survey of global gastroenterology society leadership
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Desmond Leddin, who is from the Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada, on the paper 'Climate change: a survey of global gastroenterology society leadership' published in paper copy in Gut in October 2022 and available online at: https://gut.bmj.com/content/71/10/1929 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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85
Management of Helicobacter pylori infection — the Maastricht VI/Florence Consensus Report
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Peter Malfertheiner, Gastroenterologist, who is senior Professor of Medicine at the Ludwig Maximilian University of Munich, Munich, Germany, on the paper 'Management of Helicobacter pylori infection—the Maastricht VI/Florence Consensus Report' published in paper copy in Gut in September 2022 and online at: https://gut.bmj.com/content/71/9/1724 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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84
Kyoto international consensus report on the gastro-oesophageal junction
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Sugano, Department of Medicine, Jichi Medical University, Tochigi, Japan, about the paper 'Kyoto international consensus report on anatomy, pathophysiology and clinical significance of the gastro-oesophageal junction'. The article is published in paper copy in Gut in August 2022, and available online: https://gut.bmj.com/content/71/8/1488. Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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83
A faecal microbiota signature with high specificity for pancreatic cancer
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Professor Peer Bork, Director of the Heidelberg site of the European Molecular Biology Laboratory Heidelberg, Baden, Germany on the paper 'A faecal microbiota signature with high specificity for pancreatic cancer' published in paper copy in Gut in July 2022, and available online: https://gut.bmj.com/content/71/7/1359 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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82
PICaSSO Histologic Remission Index in ulcerative colitis: a novel simplified histological score
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Dr Marietta Iacucci, Associate Professor in Gastroenterology, Institute of Immunology and Immunotherapy, University of Birmingham and Consultant Gastroenterologist, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom, on the paper "‘PICaSSO Histologic Remission Index (PHRI) in ulcerative colitis: development of a novel simplified histological score for monitoring mucosal healing and predicting clinical outcomes and its applicability in an artificial intelligence system" published in paper copy in Gut in May 2022, and available online: https://gut.bmj.com/content/71/5/889 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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81
Next-generation sequencing of bile cell-free DNA for early detection of malignant biliary strictures
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Dr Maria Arechederra, young researcher at the Hepatology Program in the Center for Applied Medical Research (CIMA) from the University of Navarra in Pamplona, Spain, on the paper "Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures" which is published in paper copy in Gut in June 2022, and available online: https://gut.bmj.com/content/71/6/1141 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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80
Endoscopic full-thickness plication for the treatment of PPI-dependent GERD
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Rakesh Kalapala, Senior Consultant Gastroenterologist & Therapeutic Endoscopist, Head of GI Motility Lab, Director of Endoscopy at the Center for Obesity & Metabolic Therapy, Member of the International Bariatric and Metabolic Endoscopy Committee, Asian Institute of Gastroenterology Hospitals, Hyderabad, India on the paper 'Endoscopic full-thickness plication for the treatment of PPI-dependent GERD: results from a randomised, sham controlled trial' which is published in paper copy in Gut in April 2022, and is available here: https://gut.bmj.com/content/71/4/686 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).
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ABOUT THIS SHOW
The Gut Podcast is your go-to source for the latest discussions in gastroenterology and hepatology. Each month Dr. Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, dives into key issues in the field by discussing articles with their authors.Gut - gut.bmj.com - is an international journal from BMJ Group and the British Society of Gastroenterology (BSG) publishing research and review articles in gastroenterology and hepatology.Stay up to date with the latest research in gastroenterology. Subscribe to the Gut podcast.* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Li
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