ID:IOTS - Infectious Disease Insight Of Two Specialists

In which Jame waxes lyrical about pharmacodynamic target attainment and its role in breakpoint setting and dosing of antibiotics, and how you can apply it in clinical practice. Take a look at the prep notes for this one, a picture says a thousand words! Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

The POET trial was the biggest endocarditis trial in some time, and since 2019 has changed how we manage these patients. But how to implement oral regimens for Endocarditis? Jame speaks to Nik Rae, Consultant Physician, on how they implemented the use of oral antibiotics for endocarditis patients in Ninewells Hospital, and how you can too! (in your own hospital, not Ninewells, the're already doing it). Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

How do you decide which antimicrobial to use? This is a follow on from episode 69, 'Choosing an antimicrobial'. We did an overview of spectrum and syndromes... But now let's dive into the details!We consider the details of how to choose an antibiotic in simple, complicated and complex situations. We also talk about the Cynefin Framework for decision making in various circumstances; Don't worry if you don't know what that is; neither did Jame before this episode was recorded! Notes for this episode here: https://idiots.notion.site/144-Choosing-an-Antimicrobial-Host-Microbe-Drug-Factors-2d76a1ea09d8814787ccfc26fe779b3a  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Paediatric AMS? Surely there aren't any issues with antimicrobial use in paediatrics?!Jame hears from Dr Charlotte Fuller and Dr Sanjay Patel that yes, yes there is a problem! And YOU can do something about it.Listen in to hear the answers to these questions:What do we know about AMR and antimicrobial use in children? What are the barriers to responsible antimicrobial use in children?How can DGH AMS teams and paediatrics support each other?  Are there any other paediatric-specific considerations for infection prevention, diagnosis and management?Where can microbiologists learn more about paediatric infection? HINT it is here: https://uk-pas.co.uk/ and here https://bsac.org.uk/paediatricpathways/ Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Access WatchReserve (IE the cool stuff)What are they? Where are they? WHO ARE THEY? Listen on and find out! (Looking at the prep notes strongly advised for this one).  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

There's nothing new under the sun... except for these new antifungals which we will now educate you on! One's an inhaled azole (OK not that new)One's sort of an echinocandin (shut up)Two are unpronounceable (but related to fungicides which we're using already)And Alyssa and Jame are joined by Dr Neil Stone, ID:IOTS Podcast Novel Antifungal Agent Correspondent, to guide you through it all!  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Callum was recently on the Primary Care Knowledge Boost podcast (https://pckb.org/), talking about what happens to microbiology specimens sent in to the lab. He did so well we thought we'd share it with you here! Enjoy... Original podcast blurb here: ---Doctors Lisa and Sara are joined by Medical microbiology and Infectious Diseases Consultant Dr Callum Mutch to follow the journey of a urine sample and a throat swab as they are processed. We discuss the important points to get right in the pre-analytical, analytical and post analytical stages of their journeys. Some fascinating insights (including how the clinical details can affect what is tested for) that have changed our practice for the better. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Process your Polyene Prescribing Paralysis by partaking in this proliferous podcast pondering on the particulars of these P-harmacological agents.* *Alyssa had no part in the making of this podcast description. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Jame and Callum are joined by Christina Petridou. In this episode we give you an overview of ticks and the key infections they transmit..., but NOT Lyme disease.Some of the infections we DO cover include: Rickettsiosis (spotted fever group), relapsing fevers, anaplasmosis, ehrlichiosis, babesiosis, TBE & CCHF. Not Lyme. THIS IS NOT A LYME DISEASE EPISODE. Show notes (including lots of summary tables and horrible tick pics) for this episode are here. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Flucytosine. A much maligned antifungal, consigned to adjuvant use in Cryptococcus... WELL THAT CHANGES... well not today because the resistance barrier is shockingly low, but at least in 20m time you'll know all you need to about 5-FC!  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Lab containment levels 1-4Safety cabinets 1-3ACDP approved list of biological agents 2-4Counterterrorism act  schedule 5 pathogensCat A and Cat B transport SAPO?!Confused? We're not surprised, but things will all become clear.... Once you listen to this masterclass from Dr Claire Gordon on all things biosafety and biosecurity from a UK lab perspective.  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

What could be more Rare Imported or Pathogenic than the Viral Haemorrhagic fevers?!Callum is joined again by Drs Claire Gordon and Amy Bellfield to talk all things VHF and HCID from the clinical lab perspective.We're sure you'll all be Very Happy Fans by the end of this one... Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Terbinafine! Griseofulvin!2 weird antifungals that the dermatologists use much more than us! But we here at the ID:IOTS Podcast love all our antifungal agents equally so here's an episode on literally everything you need to know about both these agents!  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Now this an episode, first of a triple About all the work of a lab called RIPL And we'd like to take minute now so sit right here And learn about all the horrible pathogens you now should fear Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Part 2 of 2 on Echinocandins! Tihana Bicanic gives a masterclass on Rezafungin, its use now and in the future, and gives an update on the relevant clinical trials and studies you need to know to make you a Master Echinocandologist. Alyssa and Jame are here too, but very much in receive-only mode. Listen in and find out why! Notes for this episode are found here: https://idiots.notion.site/132-133-Echinocandins-2d76a1ea09d8811f800ad3a446c6726eSupport the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Alyssa and Jame are joined by Tihana Bicanic, to discuss the second great antifungal drug class, Echinocandins. Part 1 of 2! (this episode we discuss the old stuff, next episode we discuss Rezafungin in more detail). Show note for this episode found here: https://idiots.notion.site/132-133-Echinocandins-2d76a1ea09d8811f800ad3a446c6726e(Note if you have any echo on the audio for this episode, try re-downloading the episode)Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

BIOCIDES ARE COMING FOR YOU. Find out what they are, what the benefits and harms they have, and what we can do to control their use in consumer products. This was a fascinating, wide-ranging discussion on the use of agents that can affect the human/animal microbiome and environmental microbes, and the problems with trying to regulate them (in the UK at least). Hope you enjoy it. Bios: Natalie Bennett has been a Green Party representative in the UK House of Lords for six years, after being leader of the England & Wales Party from 2012-2016. Her first degree - from the University of Sydney - was in agricultural science, and she can get very geeky about soils; she got tardigrades into Hansard (the parliamentary record) for the first time ever in her maiden speech. Her Consumer Products (Control of Biocides) Bill was introduced to the House in January 2025. Her first book is Change Everything: How We Can Rethink, Repair and Rebuild Society, and her second (Green Thinking Unlearning Outdated Ideas in Science, Economics and Politics) will be out from Routledge next April. Anastasia “Tash” Theodosiou is an Academic Clinical Lecturer at the University of Glasgow and a Specialty Registrar in Microbiology & Infectious Diseases. Her research explores how the microbiome shapes health and disease, with a particular focus on early life; her PhD produced the world’s first human challenge study performed in pregnancy. She also coined the term microbiotoxicity, a framework for recognising the unintended impacts of antimicrobial products on the microbiome, and is a passionate advocate for embedding microbiome stewardship into clinical practice, prescribing, and policy.Jame is a podcaster. He works for the NHS on occasion.  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Flustered by fluconazole? An ignoramus on itraconazole and isavuconazole?Puzzled by Posa? VEXED BY VORI? Never fear: You can be amazed at the Azoles, just learn how to use 'em right! That's what this episode's all about! Alyssa and Jame UNITE in the first of our episodes on antifungal drugs! Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

AKA Penicillin Allergy 3: Delabel Hard With A VengeanceA departure from our semi-annual penicillin allergy episode: one on cephalosporin allergy! Jame and Callum are joined by Fionnuala Cox to discuss Cephalosporin allergy in general, and the CEPH-FAST risk assessment tool in particular. Ever wanted to know how to deal with cephalosporin allergy? Listen on! Paper here: Cox F, Vogrin S, Sullivan RP, Stone C, Koo G, Phillips E, et al. Development and validation of a cephalosporin allergy clinical decision rule. Journal of Infection. 2025 June 1;90(6). Available from: https://www.journalofinfection.com/article/S0163-4453(25)00089-1/fulltexthttps://doi.org/10.1016/j.jinf.2025.106495(It's open access, don't worry) Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Yo ho ho, for our listeners dearestWe present an antibiotics tier list Ranking drugs from S to DIn a manner oh so ChristmassySo sit back relax and have a drink As we discourse in cladist thinkAnd if you rank a different wayWe'll forgive you this Christmas day. Proper episodes next year. See you in 2026!  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

In which Callum and Jame discuss Brucellosis, named after a Scottish feminist, a disease hard to diagnose but easy to treat, as long as the treatment works which it may not. Listen on!  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

It's the best pun Cal's ever done, and I don't say that lightly, son. Here's an episode on Capnocytophagia!  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

It’s World Antimicrobial Awareness Week! And did you know AMR might kill us all? The British Society of Antimicrobial Chemotherapy do, and they’ve partnered up with interested politicians to drive AMR up the political agenda. But how? Jame is joined by Dr Helen Callaby, Dr Nick Brown and Dr Danny Chambers MP to discuss the workings of the UK’s All Party Parliamentary Group on AMR, the BSAC parliamentary internship, how to get involved in pushing AMR up the political agenda, and more! Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

SporotrichosisMycetomaChromoblastomycosis...Entomophthorales.Let's face it: you don't know anything about these diseases. That's OK: neither do Callum or Alyssa. That's why we've got a guest! Dr David Chandler is a Consultant Dermatologist, BSMM member and is a member of the Global Mycetoma Working Group. Listen on for everything you need to know about chronic subcutaneous infections caused by moulds! Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Alyssa and Callum talk all things dermatophytes and Tinea:Tinea capitis – scalp, hairTinea corporis – trunk, limbs (ringworm)Tinea manuum/pedis - palms and soles (athlete’s foot)Tinea cruris - groin (jock itch)Tinea barbae - beard area and neckTinea faciale - faceTinea unguium / onychomycosis - nailsWhat does  Anthropophilic mean and how do you pronounce it? Tune in to find out.Show notes for this episode here: https://idiots.notion.site/12-Moulds-Dermatophytes-3e6b963f48db46808f67985884be5794?source=copy_linkSupport the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Alyssa and Callum are joined by Dr Neil Stone to talk all things Rare, Invasive, and Mouldy. Specifically Fusarium spp., as well as Scedosporium spp. and Lomentospora prolificans. Heard of these before? No? Well listen in to find out what they are, and why they matterShow notes for this episode here: https://idiots.notion.site/122-Moulds-Rare-invasive-moulds-af70fc26e81043669c2bf3ef17c14b6c?pvs=74Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Callum and Alyssa are joined by Dr Dora Corzo-Leon to discuss all things Mucorales and Mucormycosis. Listen in to hear about:Taxonomy (and why it is confusing)PathogenesisRisk factors Clinical syndromesDiagnosticsTreatmentShow notes for this episode here: https://idiots.notion.site/121-Moulds-Mucorales-c2343d4588ea4dd19c54de538fd7fe22?pvs=74 Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Jame is joined by Chloe from BioMerieux to discuss clinical decision support systems and their application in Microbiology & Infectious Disease! What are they, how do they work, and what are the potential applications in antimicrobial stewardship? Listen on for details! Note: This episode was produced in collaboration with BioMérieux. An honorarium received from them will be donated directly to charitable causes.Message from BioMérieux: Every effort has been made to ensure the accuracy of information shared during our podcast appearances. The views expressed by our representatives are in good faith and based on the information available at the time. We accept no liability for any errors, omissions, or discrepancies. For the most accurate and up-to-date product details, please refer to our official website or contact us directlySupport the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Callum and Jame are joined by Iain and Darius to talk through the clinical aspects of managing Aspergillosis with a particular focus on the most severe disease. Listen in to hear about current challenges around the management of both invasive and chronic Aspergillosus.Notes for this episode here: https://idiots.notion.site/118-Moulds-Aspergillus-ce3ba58d045b47b18d9641b56559c6f5?pvs=74Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Alyssa and Callum talk through Aspergillus, the first of our Moulds series. After you hear the puns in this episode you'll be fumi(n)g at us. Tune in to hear about:EpidemiologyTaxonomyPathogenesisLab identificationOn the next episode we'll be joined by some special guest to delve into the clinical aspects of the Aspergillosis.Notes for this episode here: https://idiots.notion.site/118-Moulds-Aspergillus-ce3ba58d045b47b18d9641b56559c6f5?pvs=74Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Take a break from those pesky fungi to learn about another pesky gram-negative! This week it's Pasteurella. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

In this episode Alyssa is joined by common host Callum to talk about some less common yeast pathogens: Malassezia spp., Rhodotorula ssp., Trichosporon spp. and Saccharomyces spp. Whilst we're calling these "less common" don't let that fool you - these fungi are everywhere! They are just less commonly causing severe disease in us humans!Show notes for this episode here: https://idiots.notion.site/116-Yeasts-other-yeasts-30a33d6070c84243b3f42edac4a37ec9?pvs=74Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Listen to this Pretty Comprehensive Pod on PCP. Alyssa and Callum cover:EpidemiologyTaxonomy (PCP vs PJP?)Diagnosis TreatmentNote this pod episode also includes some Positively Jolly Puns on PJPNotes for this episode here: https://idiots.notion.site/115-Yeasts-Pneumocystis-jirovecii-ac05a01902b8457688b40c07020f2c2cSupport the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Alyssa and Callum continue to speak to Jeremy Day about Cryptococcus, focusing on the evidence base for management. To further encapsulate your learning, be sure to listen to part 1 last week!Show notes for this episode here: https://idiots.notion.site/113-114-Yeasts-Cryptococcus-14fd0e7ed6a2478cb5734f1e21f49029?source=copy_linkSupport the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

In this episode we are uncovering the most cryptic of cocci, Cryptococcus!Alyssa and Callum are joined by Jeremy Day to learn all things neo(formans) about this important pathogenic yeast. In this episode we discuss the epidemiology, clinical presentations and diagnosis of Cryptococcus.To further encapsulate your learning, be sure to listen to part 2 next week!Show notes for this episode here: https://idiots.notion.site/113-114-Yeasts-Cryptococcus-14fd0e7ed6a2478cb5734f1e21f49029?source=copy_linkSupport the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

In this episode, Callum and Jame discuss the latest evidence base for endocarditis assessment & management, focusing on the ESC 2023 guidance. Echocardiography indicationsSurgeryAntimicrobial treatmentsASTAND MORE…in part 1 because this is was 2-parter.Show notes for this episode here: https://idiots.notion.site/111-112-Endocarditis-2023-Update-3594d55559314434a3b87d4c30ec41f3  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

In this episode, Callum and Jame discuss the latest evidence base for endocarditis assessment & management, focusing on the ESC 2023 guidance. Epidemiology! Prophylaxis! How to take a blood culture! A long and complicated comparison of the Duke-ISCVID and Duke-ESC criteria that doesn’t really matter because they’re both as good as each other! AND MORE…in part 2 because this is a 2-parter sorry SEE YOU NEXT TIME! Show notes for this episode here: https://idiots.notion.site/111-112-Endocarditis-2023-Update-3594d55559314434a3b87d4c30ec41f3  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

The conclusion of the Candida trilogy focuses on the rise of the Lord of the Candida resistance mechanisms: C. auris.Alyssa and Callum are joined by returning guest Professor Tihana Bicanic to discuss the rise of C. auris. Here we highlight some resources for managing this difficult to treat Candida including the recent UKHSA updated guidelines. We also discuss anti-fungal resistance mechanisms in Candida in general.Although this concludes the Candidal section, there are more yeasts yet to come!Show notes for this episode here: https://idiots.notion.site/108-110-Yeasts-Candida-0eb5f9271f654312b59458d39f8de603?pvs=74 Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Yes we've done a Candida episode, but what about SECOND Candida episode?This week in the second part of the Candida Trilogy Alyssa and Callum are joined by Professor Tihana Bicanic to discuss all things invasive Candidiasis.Listen in to hear about treatment and diagnosis of this important condition, as well as some areas of current research and the most recent guidelines from ECMM-ISHAM. (Note this episode was recorded before they were released).Show notes for this episode here: https://idiots.notion.site/108-110-Yeasts-Candida-0eb5f9271f654312b59458d39f8de603?pvs=74 Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

In this episode there will be puns where you yeast expect them...But more seriously, what does Candida albicans actually mean? What are yeasts anyway? How does this all relate to the Romans?These questions, and more, will be answered as Alyssa and Callum continue the Fungal series with this, the first in a 3-parter on all things Candida!In this episode we cover the Taxonomy (newly confusing), Epidemiology and Pathogenesis of Candida spp. before talking about superficial candidiasis.Look out for upcoming episodes on invasive Candidiasis and C. auris!Show notes for this episode here: https://idiots.notion.site/108-110-Yeasts-Candida-0eb5f9271f654312b59458d39f8de603?pvs=74 Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

What exciting times! Clinical trials into the management of SAB! SNAP publication on the horizon! But how do we interpret and apply the results of these trials to our patients? This week Jame and Callum are joined by Dr Clark Russell, Clinical Lecturer in Infectious Diseases to discuss:The difficulty in interpreting current clinical trials in SAB.The emerging concept of "low risk" SAB and how to define this.The heterogeneity of SAB and how this might be exploited.Notes for this episode here: https://idiots.notion.site/107-SAB-update-1316a1ea09d8800ba701ca7ebc8d4093 Previous episodes for the basics of Staphylococcus aureus and SABATO & SNAP trials:1. It starts with Staph65. SNAP trial protocol72. SABATO trial & 73. SABATaddendum Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Callum and Alyssa are joined by Professor Malcolm Richardson to talk about all things fungal diagnostics.In this, part 1 of 2 on diagnostics we discuss the use of biomarkers such as beta-D-Glucan and galactomannan, as well as serology and molecular techniques.Notes for this episode can be found: here.Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Callum and Alyssa are joined by Professor Malcolm Richardson to talk about all things fungal diagnostics.In this, part 1 of 2 on diagnostics we discuss the use of microscopy, histopathology and culture in diagnosing fungal infections.Notes for this episode can be found: here.Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

IT'S A BREAKPOINTS BREAKOUT!Jame and Callum are joined by the drugnamic duo of Julie-Ann Justo & Erin McCreary from the Breakpoints podcast to delve into the IDSA DTR Gram negative Guidance.Show notes for this episode are here.Breakpoints podcast can be found here: https://breakpoints-sidp.org/Lyrics: Tryin’ to use some drugs to kill these bugsErin and Julie are PK PD thugs Gonna make these two ID:IOTS look like mugsIt’s gonna be a Breakpoints BreakoutSorry the song sounds so tinny, Podcast host is doing something strange to it. Link to original MP3 here.  Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

My my! Mycology?Join Callum and special co-host Alyssa for this, the first in the all new ID:IOTS Mycology Mega-series.Here we cover:What the British Society of Medical Mycology is and what they do Why we're doing this series on fungi  The Global and UK Burden of fungal disease. The spectrum of fungal disease clinically, The taxonomy of these pathogens, and the WHO Fungal Pathogen List.Notes for this episode can be found here. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

So now, Loyal Listener, you know all about Susceptible, Sensitive at higher doses, Resistant, MICs, ECOFFs/ECVs and how to use the EUCAST breakpoints table....But what about the wild-west of bug-drug combos where there are no breakpoints?Well in this episode, Jame and Callum talk through the EUCAST approach to this situation.Show notes for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

BREAKPOINTS. We all love them. S breakpoints... R breakpoints... dash, IE, NA... Wait, dash, IA, NA, Brackets?! LISTEN ON (and read the accompanying prep notes), and soon you'll know! In this episode Jame and Callum talk through the EUCAST breakpoints table and how to interpret itShow notes for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Jame is joined by Kate from BioMérieux as they take a deep dive into the BCID2 and the Vitek Reveal, 2 new devices used for rapid identification and antimicrobial susceptibility testing of blood culture isolates.Note: This episode was produced in collaboration with BioMérieux. An honorarium received from them will be donated directly to charitable causes.Message from BioMérieux: Every effort has been made to ensure the accuracy of information shared during our podcast appearances. The views expressed by our representatives are in good faith and based on the information available at the time. We accept no liability for any errors, omissions, or discrepancies. For the most accurate and up-to-date product details, please refer to our official website or contact us directlySupport the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

This week Jame is joined by Nick and Dal from BioMérieux as they take a deep dive into the Vitek2, one of the machines available for performing Automated Antimicrobial Susceptibility Testing.Note: This episode was produced in collaboration with BioMérieux. An honorarium received from them will be donated directly to charitable causes.Message from BioMérieux: Every effort has been made to ensure the accuracy of information shared during our podcast appearances. The views expressed by our representatives are in good faith and based on the information available at the time. We accept no liability for any errors, omissions, or discrepancies. For the most accurate and up-to-date product details, please refer to our official website or contact us directlySupport the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app! 

Jame and Callum are joined by Dr Fiona McGill, lead author of the 2016 Joint Specialist Societies Meningitis Guidelines.Listen to hear an overview of the epidemiology, presentation, diagnosis and management of both bacterial and viral meningitis in the UK. Show notes for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!