PODCAST · science
Improbable Developments
by Salem Oaks
Every medicine in your pharmacy has a human story behind it. Real people doing real work and living real lives. We all have romantic ideas about scientists working late into the evening or doctors dropping everything to answer a phone call about a patient. You can almost envision the moment when one of those researchers finally solves an intellectual puzzle and leaps into action. Their eyes go from an empty stare to an alert laser-like focus. They sit a bit taller and start to read frantically. I am sure you’ve seen those movies too.But is it real? Is that how it really happens?That’s what we intend to explore in “Improbable Developments.” Each month we will talk to someone who was or is in the trenches of biopharma R&D and let them tell their story. We’ll be talking about medicines you may know and some that never saw the light of day. We’ll talk to people involved at the bench in the earliest stages through to those who run the clinical trials and present the data to re
Episodes
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Amy Grover: Building Bridges Between Patients and Biopharma
“Pharmaceutical companies sometimes have a bad rap of being, you know, big, bad pharmacy. But I learned that the patient or the people I am working with right now are just as passionate and just as dedicated to the patient community as I am.” Amy Grover, Director of Patient Advocacy at Catalyst...
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Helping the Patients He Can. For Free. For Life. - Stanley Crooke, MD, PhD
Imagine you are one of only 10 people in the world with a disease. People with ultra-rare conditions have little hope of attracting research funding to find treatments to work for them. The investments just don’t make sense to for-profit businesses. Our guest, Dr. Stanley Crooke, MD, PHD is…
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Alison Bateman-House, MPH, PhD: Not can we… but should we? Bioethics
“I don't think a bioethicist is normally who people have come to their elementary school career day. So, we are a novel breed to many people.” Alison Bateman-House, PhD That is how our latest guest on Improbable Developments reflected on her chosen profession, bioethics. It is a field where...
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Emerging Researcher: Shandra Trantham
In the last of our Emerging Researchers Series, I speak with Shandra Trantham, a Ph.D. candidate at the University of Florida. Shandra was destined for a life in science. As a young child, science and math were her favorite subjects. She and I share the childhood dream of becoming an astronaut. I...
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Emerging Research: Emily McIntosh
In the latest episode of our Emerging Researchers Series, we talk to Emily McIntosh (@MCINTOSE) a recent Ph.D. from the University of Guelph in Guelph, Ontario. Living less than an hour from Toronto, she is a big Leafs fan (that is the Maple Leafs for all you non-hockey listeners.) Emily earned…
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Emerging Researcher: Robin Powers
We continue our Emerging Researchers series with an interview with Robin Powers, a student just starting her master’s degree work. Robin is an enigma. She has a wealth of energy and a very fast-moving mind. She has dreams and aspirations that will change the world. Yet she has yet to find the…
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Emerging Researcher: Layne Rodden
We are excited to introduce our Emerging Researcher Series. Over the next 4 months, we will be talking to some people who are at various stages in their education. Each of them is excited about the research they are doing now and are looking forward to promising futures. We thought it would be...
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Ethan Perlstein: Scientific Coaching for Rare Families
We first met Dr. Ethan Perlstein on our other podcast Raising Rare. Dr. Perlstein is a biotechnology entrepreneur. Dr. Perlstein has nearly two decades of experience in biomedical research and over five years in biotech company formation and executive leadership. He holds a doctorate in molecular...
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Lynne Becker: Re-empowering TBI Patients
Put me in the game coach. These six simple words can be putting athletes, soldiers, and employees at great risk. Lynne Becker knows this from her experience building a database of traumatic brain injuries (TBI) for the department of defense. A bit closer to home, both of her daughters have...
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Mike Wenger: Improving Clinical Trial Data Transparency
Mike Wenger is Vice President of Patient Engagement at TrialScope. A brain tumor patient and software developer, Mike is passionate about patient access to clinical trials. He is spearheading TrialScope Connect, the industry’s first patient referral collective. This initiative is creating a...
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Mary Rofael, MD: Helping Companies Communicate Complex Data in Ways that Matter
“I think it is really important for the public and the patient Community to learn a little more about FDA advisory committees because these are public meetings and they're accessible for anyone to attend and learn from.” Mary Rofael, MD An FDA Advisory Committee is one of the biggest moments in…
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Rob Lambkin-Williams: Mapping Out the Quest for a COVID Vaccine
The impact of COVID-19 is literally being felt around the world. Humanity has been racing to find weapons to fight this invisible enemy. We know so very little about how the virus is operating. This can leave us feeling confused and isolated. We speak to Dr. Rob Lambkin-Williams from his home…
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Kieran Geoghegan: Life of a Scientist
"For me it was a question of dying and going to heaven for 32 years." Dr. Kieran Geoghegan was inspired by the scientific and technological breakthroughs of the NASA programs in the 1960’s. This became a lifelong quest to get to the bottom of things and resulted in a wonderful career as a…
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Robert Weker: Against All Odds
Rob Weker’s story is remarkable for many reasons. First and foremost, he has beaten cancer. Not once. Not twice. But three times. Getting the third diagnosis, this time it was pancreatic cancer, really got his attention. Only 7% of pancreatic patients live beyond 5-years. I met Rob at last year’s...
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Carol Marzetta: Living to Help Other People
This month listen to Dr. Carol Marzetta talk about how the urge to help other people has shaped her career and her life. From her earliest days as a Discovery Biologist, she has found he passion in work that tries to help people in need. She shares with us some stories about the emotional…
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Donald Kirsch: Getting to Know a Drug Hunter
We’ve all been there. You are at a party and someone asks, “So, what do you do?” Dr. Kirsch always found it hard to explain his career as a discovery scientist. He decided to write a book about it. The Drug Hunters: An Improbable Quest to DIscover New Medicines is a colorful, fact-filled…
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David Pearce: Hope Can Be Curative.
Today we hear from David Pearce, PhD, President of Innovation and Research, Sanford Health and Vice Chair, Consortium Assembly, International Rare Disease Research Consortium (IRDiRC) Dr. Pearce’s rare disease background emanates from publishing over 100 research papers on Batten Disease. David...
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Kyle Bryant: Remember Why We Are Doing All This
We welcome Kyle Bryant of the Friedreich’s Ataxia Research Alliance (FARA) to discuss his journey as a patient with Friedreich’s Ataxia (FA), as an active patient leader, and in his job as a liaison between the FA community and researchers. After being diagnosed with FA when only 17 years old…
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David Fajgenbaum, MD, MBA, MSC, FCPP
We are honored to have Dr. David Fajgenbaum as our first guest on Improbable Developments. His story is intense. Before he even earned is medical degree, he was faced by a rare life-threatening illness for which there was no treatment, let alone cure. Tune in to hear how he took a novel approach…
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Welcome to Improbable Developments!
In this, our first episode, Kevin lays out the objectives and plan for the Improbable Developments podcast. He also shares a personal story about a medicine he worked on earlier in his career.
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ABOUT THIS SHOW
Every medicine in your pharmacy has a human story behind it. Real people doing real work and living real lives. We all have romantic ideas about scientists working late into the evening or doctors dropping everything to answer a phone call about a patient. You can almost envision the moment when one of those researchers finally solves an intellectual puzzle and leaps into action. Their eyes go from an empty stare to an alert laser-like focus. They sit a bit taller and start to read frantically. I am sure you’ve seen those movies too.But is it real? Is that how it really happens?That’s what we intend to explore in “Improbable Developments.” Each month we will talk to someone who was or is in the trenches of biopharma R&D and let them tell their story. We’ll be talking about medicines you may know and some that never saw the light of day. We’ll talk to people involved at the bench in the earliest stages through to those who run the clinical trials and present the data to re
HOSTED BY
Salem Oaks
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Frequently Asked Questions
How many episodes does Improbable Developments have?
Improbable Developments currently has 20 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is Improbable Developments about?
Every medicine in your pharmacy has a human story behind it. Real people doing real work and living real lives. We all have romantic ideas about scientists working late into the evening or doctors dropping everything to answer a phone call about a patient. You can almost envision the moment when...
How often does Improbable Developments release new episodes?
Improbable Developments has 20 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to Improbable Developments?
You can listen to Improbable Developments on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts Improbable Developments?
Improbable Developments is created and hosted by Salem Oaks.
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