PODCAST · science
Invent: Life Sciences
by TTP plc
What are the biggest challenges and opportunities facing the life sciences sector? How can we overcome these challenges while unlocking the opportunities? Join host Stuart Lowe and a roster of expert guests as they unpack the past, present and future of cell and gene therapy.
Episodes
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Lessons from Season 3
In Season 3 of Invent: Life Sciences, we explored the forces redefining how tomorrow’s therapies will be developed, made, and delivered. From the challenges of scaling cell and gene therapy manufacturing to the transformative power of sustainability and AI, this season uncovered what it truly…
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Make Way for Advanced Therapies – Why Manufacturing Could be Coming to a Hospital Near You
In our last episode, we explored the manufacturing strategies that will be key to scaling advanced therapies. Now, we turn our focus to the UK, where new regulatory frameworks and regional collaboration are changing how therapies reach patients. Stuart speaks with leading experts about the...
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Automation, Access, and the Future of Manufacturing
Manufacturing can make or break the future of cell and gene therapy. In this episode, Stuart sits down with two expert guests to share how smart design, automation, and closed systems are helping to lower costs, reduce complexity, and make therapies more accessible. From scaling strategies to...
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Scaling Cell & Gene Therapies: From Breakthroughs to the Mass Market
In this two-part series, host Stuart Lowe examines the barriers and breakthroughs that will determine whether cell and gene therapies can scale. From smarter manufacturing to new policy frameworks, join leading experts as they discuss what must change for CGTs to deliver on their full potential.
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From Promise to Practice – AI's Impact on Cell and Gene Therapy Development
In this episode, Stuart explores the adoption of generative AI in the pharmaceutical industry, with a special focus on cell and gene therapy. While the application of AI for drug discovery has been well documented and a source of considerable investment for the pharmaceutical sector, we are only...
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From Plastics to Partnerships - The Path to Sustainability in Biopharma
In this episode, host Stuart explores what the sustainability goals of Big Pharma mean for those organisations, and the companies that support them. With insights from Ryan Walker, Sustainability Program Leader at Cytiva, and Wenshu Xu, Drug Discovery Tools Team Lead at TTP, we review the…
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How Climate Change and AI are Driving Innovation in Biopharma
In this two-part series, host Stuart Lowe examines two factors testing the resilience of the biopharma industry. As society simultaneously navigates a green transition alongside an AI revolution, so the biopharma industry faces mounting pressure to address its carbon emissions, deploy…
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How Innovation Can Broaden Access and Propel the CGT Industry Forward
In Part One of this two-part series, we reflected on the progress made in the Cell and Gene Therapy (CGT) industry and the importance of patient-centric development. In this episode, we dive into how we can continue to move forward, broaden access, and encourage the development of new treatments....
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Why Do We Need to Continue Innovating in the CGT Industry?
The Cell and Gene Therapy (CGT) industry has made remarkable strides, with significant advancements and the approval of groundbreaking technologies in recent years. However, have we become too dependent on older methods, and are we doing enough to ensure these new therapies are reaching as many...
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Welcome Back to Invent: Life Sciences - Season 3 Trailer
Welcome back to Invent: Life Sciences, a podcast brought to you by technology and product development company TTP. With approvals for advanced therapies on the rise, and aspirations to target larger patient populations, it’s time to take stock and reflect and on the progress made to date. In this...
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The Highlights: A look back at the best moments of Invent: Life Sciences Series 2
Throughout this series of Invent, we have brought you cutting-edge developments in the Life Sciences industry. We have spoken to a wide range of guests who have provided fascinating insights into the manufacture of cell and gene therapies, and what developments in drug testing mean for the future...
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Process Analytics: how can analytics accelerate the development and manufacture of cell and gene therapies?
Throughout this series, we’ve explored different diseases we target, the sorts of cells which are under development as therapies, and how the therapies themselves are manufactured. With all this innovation, we shouldn’t be surprised by the increased focus on the means by which processes and...
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iPSCs: how could stem cells revolutionise the manufacture of advanced therapies?
Across the life sciences industry, there is much excitement over the potential impact of stem cells in medicine. And it is clear why; these cells, which can be differentiated into any other cell type, could rewrite the playbook in terms of sourcing cellular material for advanced therapies...
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Sex and gender in medical research: how can a focus on the individual improve health outcomes for marginalised groups?
Throughout almost all of medical history, it was assumed that the average white male response to drug trials could be extrapolated to all potential recipients. But when we look at the poorer health outcomes for women and minorities, could the underlying assumptions in medical research be a...
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Organoids: how are in-vitro models revolutionising drug development and testing?
Pharmaceutical companies undertake rigorous clinical trials in order to find out which drugs are safe. But in order to better protect the people volunteering for these tests, regulators decreed that data from studies on animals would be the primary evidence needed before approving a clinical…
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The Blood Brain Barrier: can innovations in delivery help us unlock the brain?
Modern medicine has helped us develop many effective treatments for diseases found throughout the body, but we’ve yet to have the same success with the brain. The so-called 'blood brain barrier' controls the passage of molecules out of the blood and into the brain, and so it’s not as easy to use...
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Small Molecules: can new classes of drug target reinvigorate drug discovery?
In the pharmaceutical industry, there is a desire to go beyond the traditional ‘compound x acts on protein y,’ and achieve a more nuanced effect on the underlying biology. So, could innovative approaches to small molecules open up a wider application space? And what benefits might this bring to...
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Cell and gene therapy: how can we transform artisan treatments into mass-market cures?
Cell and gene therapies are extremely effective but their complex production processes, arduous supply chain, and life-critical logistics have prevented mass market adoption. Could digitisation and AI provide a breakthrough in manufacturing? Would more companies be willing to work together on...
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mRNA: What did Covid teach us about drug development and distribution?
The Covid vaccination campaign demonstrated the effectiveness of mRNA-based treatments, so what else is this technology capable of? How can we improve our manufacturing and distribution to ensure treatments are available to those who need them most? To find out, join us on Invent: Life Sciences…
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Introducing Invent: Life Science Series 2
Invent: Life Sciences is back for Season 2! Invent: Life Sciences is a podcast about the future of life science and technology, hosted by Head of Cell Gene Therapy and Biotechnology at TTP, Stuart Lowe. Each episode, we’ll be joined by the top scientists, designers, business leaders, and…
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Introducing Invent: Health Series 2
Calling all Invent: Life Sciences Subscribers! While you wait for more episodes, make sure to subscribe to our sister podcast, Invent: Health, which has just begun its second season. Listen to the trailer here now! Invent: Health sees host Matt Parker explore the fascinating future of Health...
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Life Science Investment: How to invest in change
The pandemic drastically altered the landscape for investment flowing into the Life Sciences. Not only was there more money going in, but the market needs changed too, with an unprecedented focus on scaling sectors like testing and vaccines. But what did this mean for sectors which were not on…
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Diagnostics: How to do self-testing better
In the past decade, two events have sent shockwaves through the diagnostics industry: Theranos and Covid. The first, is a parable against faking it in an industry which rightly prizes accuracy and safety. The second was an almost insatiable demand for diagnostic testing kits, where the speed of...
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Cell Therapy Manufacture: How to scale the manufacture of living drugs
Following our first episode of two focusing on cell and gene therapies, outlining the promise and practicalities of delivering curative therapies for chronic diseases, we now focus on cell therapies - so called ‘living drugs’ that are both as powerful as they are complex. Despite the impressive...
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Cell and Gene: How to make advanced therapies accessible
With therapies like cell and gene - amongst some of the most significant innovations in modern medicine - the idea of delivering cures for conditions from cancer to diabetes is now within the realm of scientific possibility. But will it be possible to provide the benefits of advanced therapies to...
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Preclinical drug development: How to simulate the human body
From cosmetics to medicines, animal testing is still widely mandated by regulators. Up to now, there have been few other ways to gather information about the potential human response to drug candidates. But are animal models still the most effective way to test drugs before we use them in humans?...
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AI: How to think differently
The hunt to discover new pharmaceuticals in areas of high unmet need can be complex, time-consuming, and costly. For every life saving therapy that hits the market, thousands and even millions of candidate drugs are rejected. A new technology could be changing the way we home in on the most...
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Synthetic Biology: How to change your genes
What is the potential of synthetic biology? A chance to create life-changing therapies by speaking cells’ very own language? Or could rogue researchers use it to turn our own biology against us? Since synthetic biology emerged as a field, the aspirations for its benefits have been as speculative…
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Genomics: How to use a $100 genome
When the first human genome was sequenced, the whole project was estimated to have cost some 3 billion dollars and took over 13 years. Now, with massively parallel Next Generation Sequencing it is possible to sequence the human genome in less than 24 hours at a cost of under $1,000. With a rapid...
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Invent: Life Sciences from TTP - Trailer
Following our thrilling first series of Invent all about health technology, the team at TTP are back with a new series all about the Life Sciences, to explore the impact of biology and technology on the life sciences sector. Life sciences are often referred to as the Fourth Industrial Revolution,...
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ABOUT THIS SHOW
What are the biggest challenges and opportunities facing the life sciences sector? How can we overcome these challenges while unlocking the opportunities? Join host Stuart Lowe and a roster of expert guests as they unpack the past, present and future of cell and gene therapy.
HOSTED BY
TTP plc
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