PODCAST · comedy
Knockout Nerds
by Knockout Nerds
Setoiyo loves sports. Darryl doesn’t. Darryl’s a nerd. Setoiyo isn’t.Comedians Darryl Charles and Setoiyo clash and connect as they school each other on their wildly different worlds—and try to make sense of everything else in between.Smart, silly, and always surprising—jump in on the convo!
Episodes
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53 - Customer Appreciation | 50 Episodes of Chaos, Culture & Comedy
We've made it past 50 episodes, and we're celebrating with an all Hot Takes edition of the Knockout Nerds. From audio to video, from sweatpants to shorts, and from boxing history to nerd-week deep dives, we've loved every minute of the journey. Most importantly, we're grateful you've been along…
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52 — A Man Called Frazier | The Second Fight of the Century & Boxing’s Blue‑Collar Legend
The Knockout Nerds return with a Knockout Week deep dive into the life of Joe Frazier. From his beginnings in Beaufort, SC to becoming an undisputed heavyweight champion and a central figure in the second Fight of the Century. Setoiyo walks through the grit, the glory, and the legacy that made...
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51 - The Most Banned Video Games Ever Made
The Knockout Nerds return with a nerd‑week breakdown of 8 video games that have been banned across the globe. Darryl walks through the laws, the morals, and the controversies that pushed these titles into censorship history. The hot takes are flowing too — Setoiyo shows empathy for scam victims,...
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50 - Jon "Bones" Jones, Supervillain
The Knockout Nerds return with a knockout week deep dive into the wild story of Jon “Bones” Jones, the youngest UFC champion ever and one of the sport’s most infamous figures. Setoiyo walks through Jones’s career. From criminal justice major to a man who really applied the curriculum, we’re...
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49 — Service as a Suck
The Knockout Nerds return with a nerd‑week deep dive into Sales as a Service, the subscription creep turning everyday products into monthly charges. Darryl explains how we got here, from retail giants to tech companies to gaming platforms like Fortnite. The hot takes are flowing too. Setoiyo…
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48 - The Curious Case of Sonny Liston
The Knockout Nerds return with a fight‑week deep dive into the story of Sonny Liston. Setoiyo walks us through Liston’s rise from Galveston to heavyweight champion, his controversial reputation, and the legacy that made him one of boxing’s most infamous figures. The hot takes are flowing too —...
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47 - Junk in Space | Orbital Debris, Elon Musk & Kessler Syndrome Explained
The Knockout Nerds are back with a full nerd week, and Darryl is breaking down the wild world of space junk: the orbital debris, dead satellites, rocket remnants, and cosmic clutter currently surrounding our planet. Learn where it comes from, where it’s headed, and how Elon Musk’s satellite...
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46 - The Birth of The Great White Hope
The Knockout Nerds return with a fight‑week deep dive into Jack Johnson and the origins of the Great White Hope. Setoiyo walks through Johnson’s rise from Galveston, Texas to Heavyweight champion, and how his success triggered a cultural backlash so intense it led to a ban on the fight footage.…
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45 - Viva La Vaccine
The Knockout Nerds return with a nerd‑week deep dive into vaccines. Darryl walks Setoiyo through how vaccines work, their history, and why mRNA technology could change the future of flu season. The hot takes are flowing too! Setoiyo calls for African parents to finally listen, and Darryl takes…
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44 - The Ballad of George Foreman
The Knockout Nerds return with a fight‑week deep dive into the remarkable story of George Foreman. Setoiyo breaks down Foreman’s journey from fearsome young champion to his joyful, faith‑driven comeback, culminating in winning the heavyweight title at 45 years old. The hot takes are flowing too!...
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43 - I Love Dialectical Materialism
The Knockout Nerds return with a nerd week exploring Dialectical Materialism through the lens of I Love Boosters. Darryl leads Setoiyo through a deep dive into philosophy, media literacy, and why it’s more than just vibes. The episode kicks off with advice on happiness and pro‑social behavior,...
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42 - The Crimes and Times of Conor McGregor
The Knockout Nerds return with a fight‑week deep dive into the crimes and controversies of Conor McGregor, the UFC’s first Double Champ. Setoiyo walks through the assaults, the chaos, and the career moments that made McGregor one of the most infamous figures in combat sports. The hot takes are...
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41 - The Greatest Video Game Console Fails
The Knockout Nerds are back with a full nerd week dedicated to the greatest video game system fails of all time. Darryl walks through the legendary flops from Nintendo, Atari, Sega, Nokia, and more. Learn about the consoles that aimed high, crashed hard, and left unforgettable marks on gaming...
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40 - Archie Moore: The Greatest Champion You’ve Never Learned Enough About
The Knockout Nerds are back (thank you for your patience), and we’re swinging for the fences with a deep dive into the legendary career of Archie Moore — one of the greatest champions in boxing history. Setoiyo walks us through Moore’s unbelievable longevity, his LeBron‑level run, and how he...
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39 - Save Water, Get a Bidet! featuring Pearlmania500
The Knockout Nerds are back, and Pearlmania500 returns for another round of chaos! Darryl is leading the charge this week with a deep dive into wastewater recycling! Find out how reverse osmosis, UV purification, and modern treatment systems can turn your old pee into water cleaner than Aquafina...
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38 - The Great White Failure featuring Pearlmania500
The Knockout Nerds are back with their first guest ever, and it’s none other than Pearlmania500, Alex Pearlman himself! Setoiyo is at the helm for fight week, walking us through the tragic highs and lows of Tommy “The Duke” Morrison, from childhood tattoos and underage toughman competitions to...
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37 – SEGA Swan Song
Darryl is at the helm this week with the full story of Sega’s rise and fall. From the lessons of the Master System through the swagger of the Genesis era to the innovations of the Dreamcast, and how a company that once ruled the 16‑bit console wars ended up stepping away from hardware entirely.…
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36 - Bite Tyson
Setoiyo is at the helm this week with a recap of Tyson vs. Holyfield II, better remembered as "The Bite Fight". We're breaking down the buildup, the fight, and moment that Mike Tyson turned headbutt frustration into dentistry. It's one of the wildest nights in boxing history that has cemented...
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35 - The Pro‑Government Episode
Darryl is nerding out this week with a reluctant, but necessary, defense of Big Government. We're tracing the tragic disasters that led to the creation of the FDA, the EPA, and landmark protections like the Clean Air Act and Clean Water Act. Bureaucracy may be annoying, but history shows why it...
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34 — Holyfield vs. Tyson: “Finally!” | The Fight That Changed Everything
Setoiyo takes the reins this week with a full breakdown of Evander Holyfield vs. Mike Tyson, the legendary 1996 showdown famously dubbed “Finally!” We dig into why this fight wasn’t just a long‑awaited matchup — it was the collision of two major comebacks, two careers on the line, and one of the...
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33- D@&# Dynamic Pricing
Darryl is at the helm this week breaking down the rise of dynamic pricing. It's everywhere: from airline tickets to concert seats to your everyday groceries. Listen up to ofind out what surveillance‑based pricing really means for consumers. How does it work? Who does it benefit? And what can we…
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32 - He's Back. Tyson and McNeely
Setoiyo continues our walk through boxing lore with the explosive return of Mike Tyson in 1995. A comeback that started with an unfortunate moment at the Miss Black America pageant and led all the way to a showdown with Medfield’s own Peter “Hurricane” McNeely. We break down the buildup, the...
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31 - A New Serial
Darryl is at the helm this week with a deep dive into the Gilgo Beach murders and the shocking updates surrounding Rex Heuermann, who has now admitted to more killings than the seven prosecutors originally alleged. Between 1993 and 2010, more than ten women were found along Gilgo Beach in Long...
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30 - Riddick, Evander, and The Fan
Setoiyo breaks down one of the most chaotic and unforgettable moments in #boxinghistory : Riddick Bowe vs. Evander Holyfield, the heavyweight championship fight on November 6, 1993, and the shocking Fan Man incident that stopped the bout mid‑round. We walk through the stakes of the rematch, the...
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29 - My Bidet And Me
Darryl is at the helm this week with the much requested deep dive into bidets. When did it start? What is it for? Why is America sticking to dirty butt behavior? We answer all those questions and more! Plus hot takes include Setoiyo on the lifestyles of the rich and famous, and an ask for...
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28 - The Legend of Buster Douglas, Part 2
Setoiyo returns with the conclusion of our deep dive into James “Buster” Douglas, the unlikely heavyweight champion who shocked the world when he toppled Mike Tyson. A story that only gets more riveting (and more confusing) from there. We break down the aftermath, the legacy, and how the upset…
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27 - The Comedy Con Con
Darryl is at the helm this week with a deep dive into the world of comedy festivals. Are they a scam, a stepping stone, or something messier in between? The Knockout Nerds break down what they’ve learned from the inside, from the promises to the pitfalls, and everything comics whisper about...
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26 - The Legend of Buster Douglas Part 1
The Knockout Nerds are back after an unforgettable night at Punchline Philly, with huge love for everyone who came. We jump into hot takes on the people who are heaven sent and Justice for Afroman before Setoiyo takes us through one of the most shocking nights in boxing history. Setoiyo covers…
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25 - Our Cartridge Tis of Thee
Darryl is at the helm this week with a nostalgic deep dive into the mighty video game cartridge. From its founder, through its surprising evolution, to why Nintendo just can’t quit it. It’s a full retrospective on the storage format that defined childhoods and refuses to die. Along the way, we…
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24 - Sugar and the Motor City Cobra
Setoiyo helms this episode with a breakdown of "Sugar" Ray Leonard and Thomas "Motor City Cobra" "The Hitman" Hearns. Watch Darryl learn all about this legendary boxing match, with hot takes about driving and what it's like to be a Drake fan. This episode is the pound for pound best! Follow us on...
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23 - Crawl Out Through The Fallout, Baby
Darryl's at the helm this week; informing Setoiyo about the Fallout franchise. Learn about the alternate history that has grown from RPG to Prime and Beyond! Plus hot takes about looksmaxxing and being an admin to the Legion of Doom. Long Live Sheiky, Baby! Follow us on Instagram…
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22 - Last of the Great White Hopes
Setoiyo returns to the helm with a deep dive into the origins and impact of the “Great White Hope,” tracing how the term started in boxing and why Gerry Cooney’s story still hits with so much weight. It’s part cultural unpacking, part tribute, and fully Knockout Nerds energy. Plus we've got some...
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21 - Home Brew 101
Darryl’s steering the ship this week with a deep dive into the wild, yeasty world of alcohol. Whether it’s beer, wine, or the hard stuff, it all starts with microscopic magic. Setoiyo’s along for the ride with hot takes on what it really means to be an eater, while Darryl tries to convince the...
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20 - The Legend of No Mas
Setoiyo is at the helm this week with the story of the fight trilogy between Sugar Ray Leonard and The Hands of Stone Roberto Durán. We round out the episode with hot takes on googling everything and Pugh FTW!
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19 - These are the Good Nerds
Darryl is running things this week with Setoiyo's introduction to speedrunning. Learn all about this subsection of gaming that is far more popular and far better for the world than you think it is. Plus we've got hot takes on AI and the comment section. Follow us on Instagram @knockoutnerdspod...
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18- Big Cat vs The Greatest
The Knockout Nerds are officially on video, where Setoiyo walks us through the iconic 1966 championship bout between Muhammad Ali and Cleveland “Big Cat” Williams, a masterclass in footwork, finesse, and pure Ali disrespect. Darryl jumps in with hot takes on the incoming auntie‑music revolution...
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Episode 17 - Peach Flavored Deceit
The Knockout Nerds are back with a nerdy dive into the world of e-cigarettes. Darryl has researched everything you need to know about those fat clouds, how they're different from your standard cowboy killers, and what you need to look out for on your next rip. Setoiyo also has strong feelings.…
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Episode 16- The GWH is Dead!
The Knockout nerds are back! After touching some snow covered grass, Setoiyo is back at the helm to break down the 2025 clash between Anthony Joshua's dazzling career and Jake Paul's very different trajectory out of Cleveland. Darryl and Setoiyo also give you some hot takes on who really has good...
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Episode 15 - The Teflon Don
Darryl’s in the driver’s seat this week, sliding into the slick, strange saga of Teflon. From miracle coating to chemical panic: it’s non-stick science meets existential dread. Setoiyo’s along for the ride, questioning everything from cookware safety to cardio logic. We're also serving a side of...
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Episode 14 - Both Hands
Setoiyo is taking the lead this week to tell us about Mike Tyson's first defeat, refereed by none other that Barbara Walters . Darryl is here to shout out Brownsville and make peace with his ever-growing list of enemies. Glove up and join the conversation! Follow us on Instagram @knockoutnerdspod...
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Episode 13 - Not Vesta, Shouts To Vesta
Darryl's leading a Nerd week with his top 3 innovations brought to you by Big War, plus a few honorable military mentions certain to make you giggle. Setoiyo is also coming through with some industrial hot takes on a weirdly popular new kink. We've made sure its never too complex to listen along...
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Episode 12 - I Like to See what the Pros Are Doing
Setoiyo takes us on an important trip to Britain in 1963 to remember the time that a young Cassius Clay almost ruined the career of Muhammad Ali. Darryl has thoughts on the edge, and you must leave the anti-Nickelback cult. Days without mentioning bidets:1 Here's a lovely picture show of the…
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Episode 11 - That Was The First Clue
Darryl is heading this episode, dragging Setoiyo into a fun discussion on Copaganda and critical media consumption. With more thoughts on America's unwelcome saints: new and old. Plus unwelcome club attention leads to more bidet talk. It's a super sized episode, dig in! *L&O gavel sounds* Follow…
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Special Episode - They Shooting in Here UFC320
Our recap on UFC 320, Live from Las Vegas! The fights were in Las Vegas, not us.
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Special Episode - It's Riyadh Season
An all hot take special edition of the Knockout Nerds has Setoiyo and Darryl giving their impressions of The Riyadh Comedy Festival. Think pieces will be written, comedians will be paid, and audiences will be entertained. The question is: Are you not? Also, more bidet talk. Shoutout to Charmin!...
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Episode 10 - That Train Is Never Late
Lively convo this episode about the way CTE and racism combine to form the Captain Planet that is UFC fighter Bryce Mitchell. Setoiyo takes Darryl on a journey through his hits, which include all the hallmarks of that uncle you won't talk to or about. Plus inspired analysis on many aspects of...
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Episode 9 - It Can't Go Higher Than 100
Darryl’s fully charged and ready to spark some chaos in this electrifying episode of Knockout Nerds. From lithium-ion meltdowns to why your scooter might be plotting arson, we’re breaking down the battery basics and the fiery consequences of tech at capitalistic capacity. Setoiyo’s riding shotgun...
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Episode 8 - I Gotta Make 5 Men Cry
Setoiyo is throwing haymakers at Darryl in this episode of Knockout Nerds with the story of George Foreman's rise, fall, and unwarranted beating of 5 men in a single night. Find out what happens when men are embarrased before they can get to therapy or The Church. Plus some hot takes on how to…
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Episode 7 - Fools Done Upset the Old Man River
It's Darryls turn to explain a topic to Setoiyo and we're going on a deep dive into AI. Learn where the rubber meets the road when it comes to generalized ai, skynet, large language models, wasted water, neural networks and the evil weirdos who are looking for ROI in them there artificially...
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Episode 6 - I'll Die For You
It’s love, leg kicks, and legacy in this joyfully chaotic recap of Anderson “The Spider” Silva’s legendary UFC debut against Chris “The Crippler” Leben. Setoiyo and Darryl break down the ballet of violence with hit percentages that feel more like poetry than stats, and somehow end up debating...
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ABOUT THIS SHOW
Setoiyo loves sports. Darryl doesn’t. Darryl’s a nerd. Setoiyo isn’t.Comedians Darryl Charles and Setoiyo clash and connect as they school each other on their wildly different worlds—and try to make sense of everything else in between.Smart, silly, and always surprising—jump in on the convo!
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Knockout Nerds
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Frequently Asked Questions
How many episodes does Knockout Nerds have?
Knockout Nerds currently has 54 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is Knockout Nerds about?
Setoiyo loves sports. Darryl doesn’t. Darryl’s a nerd. Setoiyo isn’t.Comedians Darryl Charles and Setoiyo clash and connect as they school each other on their wildly different worlds—and try to make sense of everything else in between.Smart, silly, and always surprising—jump in on the convo!
How often does Knockout Nerds release new episodes?
Knockout Nerds has 54 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to Knockout Nerds?
You can listen to Knockout Nerds on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts Knockout Nerds?
Knockout Nerds is created and hosted by Knockout Nerds.
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