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Ann Starrs and Susheela Singh, of the Guttmacher Institute, join The Lancet to talk about the need for a comprehensive package of sexual and reproductive rights.

This week, we discuss treatment approaches for uncomplicated appendicitis in children following the publication of a trial in our January 18th issue. Lead author Shawn St Peter, general paediatric surgeon and surgeon-in-chief at Children’s Mercy Hospital, Kansas City, spoke with Callam Davidson about the motivation behind the study, key findings, and what the results mean for clinical practice.

A Health Policy piece in our April issue by Tasdik Hasan and co-authors titled: Co-designing a Bangla Mental Health Sign Language Bank in Bangladesh

Can personality disorder treatments be reduced to just a few months?

In this episode, co-hosted by our Senior Editor Amy Slogrove and our Lancet Child & Adolescent Health Youth Advisory Panel member, Matea Canizares, we discuss adolescent digital intimate partner violence.

The uniqueness of each patient is at the heart of this year's World Cancer Day. In this Podcast you will hear from two cancer survivors about their unique experience with cancer and the importance of personalised cancer care not only on their bodies but also on their lives.

In Conversation with The Lancet returns with Dr Susannah Stanway, honorary consultant medical oncologist at the Royal Marsden and honorary clinical senior lecturer in Education at the Institute of Cancer Research, reflecting on London Global Cancer Week 2025.

Franck Morschhauser joins Ben Abbott of The Lancet to discuss the phase 3 EPCORE FL-1 study on epcoritamab, lenalidomide, and rituximab for relapsed or refractory follicular lymphoma, which is being presented at ASH 2025.

Professor Arnon Kater and Dr Sabina Kersting join us to discuss the results of their phase 2 trial testing a new first-line treatment regimen in chronic lymphocytic leukaemia: fixed-duration ibrutinib–venetoclax followed by MRD-guided ibrutinib–obinutuzumab intensification.

Ultra-processed foods are on the rise. Despite the emphasis placed on individual responsibility, our deteriorating diets are primarily the result of the sophisticated political tactics of a powerful global ultra-processed food industry.

Shun Lu joins Ben Abbott of The Lancet to discuss the phase 3 HARMONi-6 trial of ivonescimab plus chemotherapy as first-line treatment in advanced squamous non-small-cell lung cancer, which is being presented at ESMO 2025.

Neal Shore joins Ben Abbott of The Lancet to discuss the phase 3 POTOMAC trial of durvalumab plus BCG in BCG-naïve, high-risk non-muscle-invasive bladder cancer, which is being presented at ESMO 2025.

Walter Willett, Shakuntala Thilsted and Johan Rockström discuss the second EAT-Lancet Commission report.

Stephen Chan joins Ben Abbott of The Lancet to discuss the key messages of the Lancet Commission on addressing the global hepatocellular carcinoma burden, which is published today on World Hepatitis Day.

Rebecca Fitzgerald joins us to discuss her recent prospective real-world implementation study of capsule sponge risk stratification in Barrett’s oesophagus surveillance in the UK.

Changsong Qi joins Chloe Wilson and Ben Abbott of The Lancet to discuss their recently published phase 2 randomised controlled trial investigating Claudin-18 isoform 2-specific CAR T-cell therapy for previously treated advanced gastric or gastro-oesophageal junction cancer.

Francis Couturaud joins Chloe Wilson of The Lancet to discuss the RENOVE trial, which looks at assessing the efficacy and safety of reduced-dose versus full-dose direct oral anticoagulants in patients in whom extended anticoagulation has been indicated.

Donald Trump has taken office in the US and immediately turned his attention to dismantling the US position as a world leader in global health. How will actions taken so far affect the health of people around the world? Gavin is joined by co-host Miriam Sabin, North American Executive Editor at The Lancet, and they speak to Dr. Gavin Yamey, lead author of The Lancet's recent Commission on Investing in Health, and Director of the Center for Policy Impact in Global Health at the Duke Global Health Institute.

Michael Heneka joins Chloe Wilson and Bea Gomez Perez-Nievas of The Lancet to discuss a therapeutics paper discussing the opportunities and challenges of passive anti-amyloid β immunotherapy in Alzheimer's disease.

ROSHNI-2 was a multicentre, randomised controlled trial that investigated the efficacy of a culturally adapted, cognitive behavioural therapy-based intervention for postnatal depression in British south Asian women. Joining us to share their expertise and perspectives are chief investigator Professor Nusrat Husain, trial manager Farah Lunat, and service user representative Fehmida Motala.

Rasha Al-Lamee and Shayna Chotai join Chloe Wilson of The Lancet to discuss ESC Congress 2024 highlights.

Gavin is joined by Paul Moran and Helen Christensen to discuss The Lancet's new commission on self-harm, exploring its prevalence, cultural factors, and the crucial need for better data and compassionate care. We also talk about stigma and improving mental health services globally.

On August 14th, the World Health Organisation declared a public health emergency of international concern in relation to mpox. This was motivated, in part, by the emergence of a concerning new strain of mpox, clade 1b, which has spread rapidly across Central Africa. Joining Callam Davidson from The Lancet to discuss important clinical aspects of the current mpox outbreak are Dr Oriol Mitja, Associate Professor at the Germans Trias Research Institute in Barcelona, and Dr Hypolite Muhindo Mavoko from the Department of Tropical Medicine at the University of Kinshasa.

Natasha Pocovi joins Chloe Wilson of The Lancet to discuss a trial investigating a walking and education intervention for the prevention of low back pain recurrence in Australia (WalkBack).

14 modifiable risk factors account for 49% of dementia cases worldwide. Gavin and Jessamy are joined by Prof. Gill Livingston (UCL) and Prof. Geir Selbaek (University of Oslo) to discuss the 2024 updates to The Lancet Commission on dementia prevention.

What are the hidden costs of breast cancer? What advances in breast cancer treatment have been made, and how can we tackle the problematic inequities that remain? What needs to be done for patients with metastatic breast cancer? Gavin and Jessamy are joined by Felicia Knaul, Reshma Jagsi, and Fatima Cardoso to discuss the recent Lancet Breast Cancer Commission.

Prasad Kulkarni joins Callam Davidson of The Lancet to discuss the safety and immunogenicity of a bivalent conjugate vaccine against typhoid and paratyphoid, following the publication of a phase 1 trial.

Jessamy and Gavin are joined by Prof. Gita Mishra, life course epidemiologist at the University of Queensland, to discuss her work on understanding early menopause. How many women does early menopause affect? How can we improve gaps in care? What are the consequences of early menopause, and what does menopause onset look like around the world?

Patricia Campbell and Frans Rutten join Chloe Wilson for an educationally-focused podcast, discussing the key messages for clinical practice on heart failure with preserved ejection fraction.

The phase 3 trial of the new R21/Matrix-M malaria vaccine was published in The Lancet this month, and the results suggest a turning point in the fight against malaria. Gavin is joined by Professor Sir Adrian Hill, one of the creators of the vaccine, to discuss the process the vaccine went through, the history of malaria vaccine research, and what the future holds.

Lene Seidler joins Callam Davidson of The Lancet to discuss umbilical cord clamping strategies at preterm birth following the publication of two systemic review and meta-analyses with individual participant data.

Emily Chew joins Chloe Wilson of The Lancet to discuss the future of treatments for geographic atrophy following the publication of two randomised controlled trials of new drug treatments.

Simon Kyle joins Gavin Cleaver of The Lancet to discuss his paper on sleep restriction therapy as a new effective treatment for insomnia.

Editor-in-chief of The Lancet Richard Horton looks back at two centuries of medical publishing, previews how we will be marking the journal’s 200th anniversary, and explains what the milestone means to him.

Dr. Anthony Fauci, Chief Medical Advisor to the President of the United States and Director of NIAID, is standing down at the end of 2022. He joins Gavin and Jessamy to discuss becoming a household name during the COVID-19 pandemic, why scientific discourse in the USA is broken, and how the pandemic could end.

How does health shape politics? How does politics shape health? Why do some diseases get international attention and funding when others don’t? What role do institutions play? Richard Horton, Eduardo Gomez, and Jeremy Shiffman join Jessamy and Gavin to discuss the talking points from a new Lancet Series on Political Science and Health.

In 2019 there were 8.6m deaths globally among children and adolescents aged 0-20 years. Almost two decades on from The Lancet’s first ever global health series, on child survival, we've published our new Series, Optimising Child and Adolescent Health and Development. Richard Horton reflects on the progress and setbacks across 20 years of child health and global health.

Ibrahim Abubakar, Tolullah Oni, and Obinna Onwujekwe join The Lancet Voice to discuss how Nigeria's history affects the modern-day health system, and the challenges and opportunities for Nigeria in the future.

On this International Women's Day, Lancet editors and the co-chairs of the Women and Cancer Commission discuss the burden of women’s cancer on society and reflect on the questions the Commission is trying to answer.

Professor Samuel K. Roberts joins Gavin and Jessamy to discuss racial inequities in the USA and how infectious diseases historically find and exploit the gaps in societies.

Nick James discusses the key messages of the recent report from the STAMPEDE trial platform and the success of this platform in advancing the treatment of prostate cancer.

Climate research pioneer Prof. Michael E. Mann joins the podcast to lay out the most important things that happened at COP26.

Why are the countries which currently suffer the most direct health impacts from climate change some of the least likely to publish climate research? In the lead-up to COP26, Prof. Penny Murage of LSHTM discusses the field and her community work in sub-Saharan Africa, and Ayesha Tandon of CarbonBrief talks about her recent piece on inequality in climate research.

Vaccine-rich countries are beginning programmes of COVID-19 vaccine booster shots, but what's the evidence for them? What does this mean for countries which have no vaccines? Prof. Sir Richard Peto and Prof. K. Srinath Reddy discuss.

What are the most pressing humanitarian needs in Afghanistan? How can the country preserve its health system? Former Afghanistan government public health director Dr. Mohammad Haqmal and Dr. Ayesha Ahmad highlight the main issues, and Prof. Muhammad Zaman discusses the changing needs of refugees worldwide as a result of the COVID-19 pandemic.

The mental health of health workers is often overlooked, but with the pandemic still raging around the world, a conversation about their wellbeing is vital. In this episode we speak to Pier Bryden, Julie Maggi, and Lisa Richardson about their work in the Temerty Faculty of Medicine at the University of Toronto, and to Sam Harvey of the Black Dog Institute in Sydney about his new Review of the subject.

Adrian Bauman and Masamitsu Kamada discuss why the Olympics don't seem to have much of an effect on physical activity levels in their host countries.

Helena Wang discusses The Lancet Commission on women's reproductive, maternal, newborn, child and adolescent health (RMNCAH) in China with author Professor Jie Qiao.

《柳叶刀》亚洲执行主编王辉对话《柳叶刀中国女性生殖、孕产妇、新生儿、儿童和青少年健康重大报告》共同主席乔杰院士。

Commissioners Michael Anderson and Emma Pitchforth explain the findings of their Commission on the future of the NHS, and Jennifer Dixon of The Health Foundation discusses health and care in the UK.