Medical Breakthroughs from Penn Medicine

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Elise Chong, MD Patients with follicular lymphoma who relapse or don’t respond to treatment don’t have many therapeutic options, but a recently FDA-approved CAR T-cell therapy may help change that. Dr. Charles Turck is joined by Dr. Elise Chong from Penn Medicine’s Abramson Cancer Center to explore this new treatment option.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Kirstin Leitner, MD Current screening tools for postpartum depression may have limitations, but a new texting service as part of the Healing at Home program may help clinicians detect postpartum depression earlier. Dr. Charles Turck is joined by Dr. Kirstin Leitner to take a look at this program and its impacts.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Kathryn Gallagher, MS, RN, BSN Guest: Kate Newcomb-DeSanto, MSN, RN, MSW What does Penn Medicine’s newly-opened patient room facility have to offer? Dr. Charles Turck is joined by Penn Medicine Clinical Advisors Kathy Gallagher and Kate Newcomb-DeSanto to discuss the new pavilion and how it's revolutionizing patient care.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Drew Weissman, MD, PhD Dr. Drew Weissman, Professor of Medicine at Penn Medicine joins Dr. Turck to discuss his new COVID-19 vaccine technology and how RNA and mRNA are being used to provoke an immune response in order to combat the COVID-19 pandemic.

Host: Jennifer Caudle, DO Guest: Kathleen E. O'Neill, MD, MTR Guest: Nawar Abdul Latif, MD, MPH, MSCE Patients with uterine factor infertility, or UFI, only had two options if they wanted to achieve parenthood: using a gestational carrier or adoption. Until now. Joining Dr. Jennifer Caudle to talk about the opportunities of uterine transplants and key information about the UNTIL trial are lead investigators Drs. Kathleen O’Neill and Nawar Latif from Penn Medicine.

Host: Jennifer Caudle, DO Guest: Amit Bar-Or, MD, FRCP, FAAN, FANA Joining Dr. Jennifer Caudle to discuss the latest research furthering our understanding and treatment of multiple sclerosis is Dr. Amit Bar-Or, Chief of the Multiple Sclerosis Division and Director for the Center of Neuroinflammation and Neurotherapeutics at Penn Medicine. Could these recent findings finally help us solve some of the unanswered questions of multiple sclerosis?

Host: Jennifer Caudle, DO Guest: Anjali Owens, MD Without any targeted therapies available for inherited cardiomyopathy, how can we treat our patients coping with its debilitating symptoms? Here to share her diagnostic and management strategies along with key data from a recent study is Dr. Anjali Owens, Medical Director at the Center for Inherited Heart Disease at Penn Medicine.

Host: Matt Birnholz, MD Guest: Howard C. Herrmann, MD Twelve years after performing the first transcatheter aortic valve replacement, Penn Medicine continues to gain momentum in the transformation of cardiovascular transcatheter therapies. Dr. Howard Herrmann recounts the evolution in alternative technologies to improve patient safety and outcomes and the role these advancements have in shaping how we approach treatment.

Host: Jennifer Caudle, DO Guest: Suhail K. Kanchwala, MD Improving his patients’ post-surgical experience was Dr. Suhail Kanchwala's goal when he sought to develop a new method for autologous breast reconstruction. The result of his search has brought a new technique to the field, along with an array of benefits for patients, including reduction of post-surgical pain and opioid use.

Host: Barnett Mennen, MD Guest: Comron Saifi, MD Spinal deformity places strain on the vertebrae and supporting muscles, tendons, ligaments, and tissues supporting the spinal column. The treatment and management of this condition becomes centrally important to maintain patient quality of life through functional mobility and activity levels. Host, Dr. Barry Mennen and Dr. Comron Saifi discuss the leading assessment and treatment options for spinal deformity. Dr. Saifi is an Assistant Professor of Orthopaedic Surgery in the Division of Spine Surgery at the Perelman School of Medicine at the University of Pennsylvania.

Host: Barnett Mennen, MD Guest: Grace Wang, MD, FACS Unclogging patient arteries is a key step to preventing stroke in patients with arterial disease. Whether it be preventing the operative stage, or surgery itself, advances in treatment at Penn Medicine are seeking to lessen the effects of arterial disease. Host Dr. Barry Mennen welcomes Dr. Grace Wang, vascular surgeon and Director of the Vascular Laboratory at the Hospital of the University of Pennsylvania. Dr. Wang highlights the importance of early detection in arterial disease, as well as the symptoms and risk factors of the disease. She will also discuss the current and upcoming surgical intervention options at Penn Medicine.

Host: Jennifer Caudle, DO Guest: Vincent Lo Re, MD, MSCE In 2014, the CDC estimated a total of 2,194 cases of acute hepatitis across 40 states and estimates that 2.7-3.9 million people in the United States have chronic hepatitis C. Of every 100 persons affected by the disease, 75 to 85 will go on to develop chronic infection, 60 to 70 will go on to develop chronic liver disease, 5 to 20 will go on to develop cirrhosis over a period of 20–30 years, and 1 to 5 will die from the consequences of chronic infection (liver cancer or cirrhosis). Joining our host, Dr. Jennifer Caudle, is Dr. Vincent Lo Re, Assistant Professor of Medicine and Infectious Diseases and Epidemiology at Penn Medicine. Dr. Lo Re discusses the current screening guidelines and recommendations regarding hepatitis C, long-term patient care, and the current landscape of treatment options.

Host: Matt Birnholz, MD Guest: Patrick J. Connolly, MD Back and neck pain is extremely common, with 80-90% of people experiencing some pain within their lifetime. About 90% of cases resolve within six weeks, but for those patients whose pain persists, questions arise as to who should be referred next for further consultation. While patients often see a spine specialist at first, the care journey sometimes leads to a neurosurgeon or orthopaedic spine surgeon. Can this pathway from primary care to neurosurgery or orthopaedic surgery ever be expedited? Dr. Patrick Connolly, neurosurgeon at Penn Medicine joins host Dr. Matt Birnholz to discuss when primary care physicians should consider referring patients to neurosurgeons for neck and back pain. Dr. Connolly will also discuss the different types of surgical options for patients seeking prolonged back and neck pain relief.

Host: Matt Birnholz, MD Guest: Robert H. Debbs, DO Joining Dr. Matt Birnholz to discuss counseling methods for patients who are trying to conceive is Dr. Robert Debbs, Director of the Pennsylvania Hospital Maternal Fetal Medicine Network in New Jersey and Clinical Professor of Obstetrics and Gynecology at Penn Medicine. Dr. Debbs will discuss pre-conceptual counseling on a range of topics such as obesity, congenital heart disease, depression, and conceiving after a miscarriage.

Host: Matt Birnholz, MD Guest: Paris D. Butler, MD, MPH Host Dr. Matt Birnholz welcomes Dr. Paris D. Butler, who will be discussing breast reduction surgery for women who suffer from chronic back pain and breast cancer patients undergoing reconstructive surgery following a diagnosis. Dr. Butler will go into detail about the pros and cons of taking an immediate versus a delayed reconstruction approach and the various techniques associated.

Host: Jennifer Caudle, DO Guest: Michael Mullen, MD Every second counts for stroke patients. During a stroke, two-million brain cells die every minute, making the urgent administration of therapies and treatment vital to ensure a positive outcome. Host Dr. Jennifer Caudle is joined by Dr. Michael Mullen, Assistant Professor of Neurology at Penn Medicine. They discuss the clinical hallmarks and priority treatment consideration for stroke.

Host: Jennifer Caudle, DO Guest: Joseph Berger, MD, FACP, FAAN, FANA Multiple sclerosis is a notoriously difficult disease to diagnose early on. With no singular confirmatory tests yet available, physicians often become reluctant to identify MS in their patients, leading to years of diagnostic and treatment uncertainty. But new innovations are helping doctors establish earlier diagnoses and start more targeted treatments for MS patients. Dr. Jennifer Caudle welcomes Dr. Joseph Berger, Professor of Neurology at Penn Medicine, to explore some of these innovations advancing MS diagnosis and treatment.

Host: Jennifer Caudle, DO Guest: Kathryn Davis, MD, MTR Guest: Timothy Lucas, MD, PhD According to the epilepsy foundation, epilepsy is the 4th most common neurological problem in the U.S. – only migraine, stroke and Alzheimer’s disease occur more frequently. The average incidence of epilepsy each year in the U. S is estimated at 150,000, or 48 for every 100,000 people. Host Dr. Jennifer Caudle talks with Doctors Kathryn Davis and Timothy Lucas about advances in treatment for epilepsy at Penn Medicine. Dr. Davis is Assistant Professor of Neurology and Medical Director of the Epilepsy Monitoring Unit and Epilepsy Surgical Program. Dr. Timothy Lucas is Assistant Professor of Neurosurgery, Surgical Director at the Penn Epilepsy Center, and Director of the Penn Center for Laser Neurosurgery.

Host: Shira Johnson, MD For the first time, Penn Medicine surgeons were able to complete a bilateral hand transplant on a child. The surgical team successfully transplanted donor hands and forearms onto 8-year-old Zion Harvey who, several years earlier, had undergone amputation of his hands and feet and a kidney transplant following a serious infection. Host Dr. Shira Johnson sits down with Dr. Scott Levin, who led the surgical team and is Chairman of the Department of Orthopaedic Surgery at Penn Medicine. They discuss this remarkable, groundbreaking surgery.

Host: Jennifer Caudle, DO Guest: K. Akaya Smith, MD Pulmonary Arterial Hypertension (PAH): Who is at greatest risk for developing it? What do practitioners need to know about diagnosing, treatment and the overall prognosis? Host Dr. Jennifer Caudle welcomes Dr. Akaya Smith, Medical Director for Pulmonary Hypertension Program and Assistant Professor of Medicine at the Hospital of the University Pennsylvania. Dr. Smith answers these questions, as well as, the Penn Center of Excellence for Pulmonary Hypertension.

Host: Jennifer Caudle, DO Guest: Francis Marchlinski, MD Host Dr. Jennifer Caudle welcomes Dr. Francis E. Marchlinski, Richard T. and Angela Clark President's Distinguished Professor and Director of the Electrophysiology Laboratory at the University of Pennsylvania. Dr. Marchlinski will review the epidemiology of PVCs, the kinds of problems that PVCs can cause, and how these problems manifest as symptoms in patients. He will also review the effectiveness of catheter ablation as a current treatment option for ventricular tachycardia (VT), a potenially serious complication of PVC's.

Host: Barnett Mennen, MD Guest: Deepak Sudheendra, MD, FSIR, RPVI Host Dr. Barry Mennen joins Dr. Deepak Sudheendra, Assistant Professor of Clinical Radiology & Surgery at the Hospital of the University Of Pennsylvania Perelman School Of Medicine. Dr. Sudheendra will explain the difference between acute, subacute, and chronic deep vein thrombosis (DVT) and their complications. He will also discuss the scope of post thrombotic syndrome (PTS) and why it is so important to treat quickly and effectively.

Host: Jennifer Caudle, DO Guest: Timothy W.I. Clark, MD Host Dr. Jennifer Caudle welcomes Dr. Timothy Clark, Associate Professor of Clinical Radiology and the Director of Interventional Radiology at Penn Presbyterian Medical Center. Dr. Clark will review the prevalence of peripheral arterial disease (PAD) in the U.S., the central risk factors, and how PAD is properly diagnosed and managed. He will also review advanced endovascular procedures for PAD and other therapies that make a difference in patient care and outcomes.

Host: Jennifer Caudle, DO Guest: Yuli Kim, MD Advancements in cardiac surgery and medical care for pediatric patients over the past decades have produced a sizeable population of adults living with congenital heart disease. These adults and their unique health care needs expose an emerging gap in expertise for the cardiology community, where training in congenital heart disease management has traditionally been the provence of pediatric subspecialists. How can these adult patients find cardiologists familiar with their particular anatomy and problems, and what special care strategies must cardiologists be familiar with to provide optimal care? Dr. Jennifer Caudle will discuss the selective health care needs and personalized management strategies for adults with congenital heart disease with Dr. Yuli Kim, Medical Director of the Philadelphia Adult Congenital Heart Disease Center and Assistant Professor of Medicine & Pediatrics at the University of Pennsylvania and the Children's Hospital of Philadelphia.

Host: Barnett Mennen, MD Guest: Angela DeMichele, MD, MSCE Penn Medicine’s Breast Cancer Translational Center of Excellence (TCE), known as the 2-PREVENT TCE is led by Drs. Lewis Chodosh and Angela DeMichele. 2-PREVENT TCE aims to address one of the greatest challenges in breast cancer treatment: the high rate of relapse and late treatment effects among breast cancer survivors. Host Dr. Barry Mennen welcomes Dr. Angela DeMichele, the Alan and Jill Miller Endowed Chair in Breast Cancer Excellence, Professor of Medicine and Epidemiology, and Co-Leader of the Breast Cancer Research Program at the Abramson Cancer Center of the University of Pennsylvania School Of Medicine.

Host: Jennifer Caudle, DO Guest: Nimesh Desai, MD Complex aortic diseases, feared by clinicians and the general public alike, are often labeled "silent killers" due to their unnerving pattern for developing insideously prior to presenting as acute crises. Even more concerning, the symptoms of aortic diseases are typically vague and difficult to diagnose without a high degree of clinical suspicion. For these reasons, the speed of diagnosis and treatment can determine whether patients live or die from aortic disease. Host Dr. Jennifer Caudle welcomes Dr. Nimesh Desai, attending cardiac surgeon and Director of the Thoracic Research Program at the University of Pennsylvania, to discuss innovative medical and surgical approaches to complex aortic diseases. The two categorize these disease states specifically, examine which patient populations are at highest risk, and review methods to help clinicians reach faster life-saving diagnoses.

Host: Shira Johnson, MD Guest: Joseph M. Serletti MD Reconstructive microsurgery, where specialized operating microscopes and precision instrumentation are utilized to perform intricate operations in very small fields, is a rapidly evolving specialty. Dr. Joseph Serletti, Chief of the Division of Plastic Surgery at the University of Pennsylvania Perelman School of Medicine, oversees the largest reconstructive microsurgery program by volume in the country, performing over 700 free tissue transfers for breast, head & neck, and extremity reconstructions. Dr. Serletti joins host Dr. Ashira Johnson discusses the nuances of these complex procedures, as well as updates on the next horizons in reconstructive microsurgery such as facial and hand tranplants and replants.

Host: Shira Johnson, MD Guest: Sunil Singhal, MD The clinical ramifications for adding special fluorescent features to tumors at various stages of malignancy and penetration are enormous. But how do surgical, oncologic, and radiological specialists create these glowing tumors, what impacts do such markers have on clinical care, and which patient populations benefit most from this approach? Host Dr. Ashira Johnson welcomes Dr. Sunil Singhal, Director of the Thoracic Surgery Research Laboratory and Assistant Professor of Surgery at the University of Pennsylvania. Dr. Singhal reviews the use of fluorescence in tumors, articulating how new and emerging applications for this technology will advance the field of oncologic surgery.

Host: Barnett Mennen, MD Guest: Maarouf Hoteit, MD Hepatocellular carcinoma is one of the top ten causes of cancer death in the United States, and is the most rapidly increasing cause of cancer death in men. What's more, incidence rates are on the rise. For these reasons, understanding the nuances of early liver cancer detection, and treating underlying liver diseases prior to cancer development, have been more urgently needed. Joining Dr. Barry Mennen to discuss diagnostic, medical, and surgical priorities for managing hepatocellular carcinoma is Dr. Maarouf Hoteit, Assistant Professor of Clinical Medicine, Director of the Multidisciplinary Liver Tumor Clinic, and Program Director of the Transplant Hepatology Fellowship at the University of Pennsylvania Perelman School of Medicine.

Host: Jennifer Caudle, DO Guest: G. Russell Huffman, MD, MPH Host Dr. Jennifer Caudle welcomes Dr. G. Russell Huffman, Associate Professor and Director of the Shoulder and Elbow Fellowship at the University of Pennsylvania. Dr. Huffman provides an overview of the various types of elbow injuries, treatment options for athletes at all levels, and special considerations for those who require surgery. Dr. Huffman focuses in particular on updated techniques in ulnar collateral ligament reconstruction, otherwise known as the Tommy John surgery.

Host: Jennifer Caudle, DO Guest: James L. Carey, MD, MPH What happens when articular cartilage is damaged? And what are the differences between focal cartilage defects and arthritis? Joining Dr. Jennifer Caudle to discuss current mechanistic understandings of articular cartilage is Dr. James Carey, Director of the Penn Center for Cartilage Repair and Osteochodritis Dissecans Treatment; and, Assistant Professor of Orthopaedic Surgery at Penn Medicine

Host: Brian P. McDonough, MD, FAAFP Guest: Samir Mehta, MD Patients of all ages can be affected by a traumatic injury. These injuries can be complex to treat and may involve multiple parts of the body. And, in traumatic situations, decisions need to be made quickly. Host Dr. Brian McDonough welcomes Dr. Samir Mehta, Assistant Professor in the Department of Orthopaedic Surgery at the Perelman School of Medicine; and, Chief of the Orthopaedic Trauma and Fracture Service at the University of Pennsylvania.

Host: Jennifer Caudle, DO Guest: Christian A. Bermudez, MD Christian A. Bermudez, MD is the Surgical Director of Lung Transplantation and ECMO, Director of Thoracic Transplantation, and Associate Professor of Surgery at the Hospital of the University of Pennsylvania. Dr. Bermudez discusses current technologies used in lung transplantation, including mechanical support as a bridge to oxygenation during the procedures themselves. He also reviews the role of Extracorporeal Membrane Oxygenation (ECMO) in lung transplantation.

Host: Jennifer Caudle, DO Guest: Scott O. Trerotola, MD, FACR, FSIR Is there a way to predict complex removal of inferior vena cava filters, and if so, what is the success rate? Dr. Scott Trerotola adresses these and other questions in details. Dr. Trerotola is Stanley Baum Professor at the Hospital of the University of Pennsylvania, Chief of Vascular and Interventional Radiology and Vice Chair for Quality of the Department of Radiology at the University Of Pennsylvania Medical Center.

Host: Jennifer Caudle, DO Guest: Gary M. Freedman, MD Proton therapy is currently used to treat brain, spinal and prostate cancers, as well as many other tumors. Another potentially significant application is the treatment of breast cancer. Dr. Gary Freedman, Associate Professor of Radiation Oncology at the Hospital of the University of Pennsylvania, discusses advances in proton therapy in breast cancer in association with a national study currently underway at Penn Medicine. Click here for more information about the active trials on proton for breast cancer, or you can visit clinicaltrials.gov for enrollment information.

Host: Jennifer Caudle, DO Guest: Pavan Atluri, MD What are the latest advances in minimally invasive & robotic operations? And, which patients are candidates for robotic procedures? Host Dr. Jennifer Caudle welcomes Dr. Pavan Atluri, Assistant Professor of Surgery; Director of the Cardiac Transplantation and Mechanical Circulatory Assist Program; and, Director of the Minimally Invasive and Robotic Cardiac Surgery Program in the Division of Cardiovascular Surgery at the University of Pennsylvania. Dr. Atluri will discuss the latest advancements at Penn Medicine where he and his colleagues have been working for several years to perfect the robotic, minimally invasive, mitral valve repair procedure. And, don't forget to view some of the additional content below.

Host: Lee Freedman, MD When a patient's facial structures are severely impacted by trauma or disease, the physical and psychological tolls are devastating. What are some of the latest advances in facial reconstruction? Joining Dr. Lee Freedman are Dr. Steven Cannady, Assistant Professor of Clinical Otorhinolaryngology: Head and Neck Surgery, and Dr. Oren Friedman, Director of Facial Plastic Surgery and Associate Professor of Clinical Otorhinolaryngology: Head and Neck Surgery, both at Penn Medicine.

Host: Lee Freedman, MD Given the multitude of concerns a male patient with cancer must deal with, sexual dysfunction and infertility are two such concerns that often gets bypassed by clinicians addressing more "priority" issues. What kinds of challenges do these patients deal with, and how can physicians better assess and manage them? Joining Dr. Freedman to discuss sexual health and fertility in male cancer survivors is Dr. Puneet Masson, Director of the Male Infertility Program and Assistant Professor of Urology at Penn Medicine.

Host: Lee Freedman, MD Osteosarcoma is a relatively rare but feared disease. What exactly is an osteosarcoma and how should it be worked up and treated? Host Dr. Lee Freedman discusses this diagnosis with Dr. Kristy Weber, Abramson Family Professor in Sarcoma Care Excellence and Professor, Vice-Chair of Faculty Affairs, Department of Orthopaedic Surgery; Director of the Sarcoma Program, Abramson Cancer Center; Chief, Orthopaedic Oncology.

Host: Lee Freedman, MD Oropharyngeal cancer is part of a growing proportion of head and neck malignancies. This has also been associated with the increase in infection of the oropharynx by oncogenic strains of the human papillomavirus (HPV). And, transoral robotic surgery, or TORS, has allowed for minimally invasive surgery for HPV-related and non-HPV-related oropharyngeal cancer. To discuss this topic and much more, host Dr. Lee Freedman welcomes Dr. Gregory Weinstein, Professor and Vice Chair and the Director of the Division of Head and Neck Surgery. He is also the Co-Director of The Center for Head and Neck Cancer in The Department of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania.

Host: Lee Freedman, MD Cerebrovascular Neurosurgery is the highly specialized care for all aspects of cerebrovascular disease. What are the most common diseases treated by a cerebrovascular neurosurgeon? What are the latest treatment options and advances in this field? Host Dr. Lee Freedman welcomes Dr. Michelle Smith, Assistant Professor of Neurosurgery at the Hospital of the University of Pennsylvania, to discuss these questions and much more.

Host: Lee Freedman, MD Patients with ulcerative colitis often need to take multiple medications to achieve and sustain remission. But there is a pionering surgical approach, the laparoscopic J-pouch procedure, that can not only cure patients from this disease, but also eliminate risk of future colorectal cancer. Dr. Najia Mahmoud, Chief of the Division of Colon and Rectal Surgery and Associate Professor of Surgery at the Hospital of the University of Pennsylvania, joins Dr. Lee Freedman to discuss the risks and benefits of this procedure for patients with ulcerative colitis.

Host: Lee Freedman, MD Host Dr. Lee Freedman is joined by Francis Marchlinski, MD, Director of Electrophysiology at the University of Pennsylvania Health System; and, the Director of Electrophysiology Laboratory, Hospital of the University of Pennsylvania. In this segment, Dr. Marchlinski discusses premature ventricular contractions (PVCs), when to consider catheter ablation, the use of catheter ablation as primary therapy before medication and epicardial ablation.

Host: Lee Freedman, MD Heated/Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is one of the most innovative treatments available today for complex abdominal cancers. What is it? Who is a candidate? And, what are the expected outcomes for our patients? Host Dr. Lee Freedman welcomes Dr. Giorgos Karakousis, Assistant Professor of Surgery at the Hospital of the University of Pennsylvania to discuss HIPEC.

Host: Lee Freedman, MD How does surgery and stenting for carotid lesions help prevent stroke? What are the latest approaches, clinical trials, and philosophy for dialysis access for patients? Host Dr. Lee Freedman welcomes Dr. Benjamin Jackson to answer these questions and the latest innovations in vascular surgery at the University of Pennsylvania Hospital. Dr. Jackson is an Assistant Professor of Surgery in Radiology at the University of Pennsylvania Hospital.

Host: Lee Freedman, MD Joining host Dr. Lee Freedman is William C. Welch, MD, FACS, FICS, Professor of Neurosurgery and Professor of Orthopaedic Surgery, and Vice Chair of the Department of Neurosurgery at Pennsylvania Hospitall. Dr. Welch will discuss the surgical treatment options for both lumbar spinal stenosis and cervical stenosis. He will also explore the causes and treatment options for lower back pain.

Host: Lee Freedman, MD Hip pain can be a major roadblock to an active lifestyle, and even effect activies of daily living. This is sometimes even more profound when seen in younger patients. How can we preserve hip function in younger patients, for whom replacement is not an option? In this segment, Dr. Lee Freedman speaks to Dr. Atul Kamath, Director, Center for Hip Preservation and Assistant Professor of Orthopaedic Surgery at the Hospital of the University of Pennsylvania.

Host: Lee Freedman, MD According to the American Cancer Society, about 10,000 pituitary tumors are diagnosed each year in the United States. What is the state of the art approach to the diagnosis and treatment of these tumors? Dr. Lee Freedman talks to Dr. Sean Grady, Chairman, Department of Neurosurgery Charles Harrison Frazier Professor of Neurosurgery Perelman School of Medicine at the University of Pennsylvania.

Host: Lee Freedman, MD Presentation of lumps and bumps are common in the primary care setting, but the appropriate approach is vital to determine whether there may be a deeper problem. A better understanding can lead to more effective treatment. Expert guest Dr. Kristy Weber discusses musculoskeletal tumors during her discussion with host Dr. Lee Freedman. Dr. Weber is the Abramson Family Professor in Sarcoma Care Excellence as well as Professor, Vice-Chair of Faculty Affairs, Department of Orthopaedic Surgery; and Director of the Sarcoma Program, Abramson Cancer Center; and Chief, Orthopaedic Oncology.

Host: Lee Freedman, MD What are the new advances in Head and Neck Cancer? What are the new trials in sparing patients' voice box? To answer these questions and more, host Dr. Lee Freedman is joined by radiation-oncologist Alexander Lin, MD, Assistant Chief, Head and Neck Service, University of Pennsylvania Department of Radiation Oncology and Director of Clinical Proton Operations, University of Pennsylvania, Department of Radiation Oncology at the Roberts Proton Therapy Center at the University of Pennsylvania.