PODCAST · health
Microdose U - Psilocybin Microdosing for Depression and Anxiety
by Dr. David M. Madow
My name is Dr. David Madow, and I’m the founder and host of Microdose U, a podcast focused on psilocybin microdosing for depression, anxiety, PTSD, and overall mental health. Not long ago, I was barely hanging on. Daily life was filled with fatigue, anxiety, depression, and a complete lack of motivation. I tried medications, psychotherapy, meditation, yoga, and everything else I was told might help. Nothing truly worked. Then I discovered psilocybin. Through Microdose U, I share my personal journey from the very beginning, along with real conversations, lived experience, and honest exploration of microdosing as a tool for healing and growth. This podcast is about hope, curiosity, and finding a way forward when traditional paths fall short. All content is shared for educational and informational purposes only. I am sharing my personal story and experiences, not giving medical advice. Always consult your healthcare provider and follow all local laws before using psychedelics.
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The 2027 Beginner’s Guide to Microdosing Psilocybin: A Doctor Explains What to Expect
If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one: https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected]. The post The 2027 Beginner’s Guide to Microdosing Psilocybin: A Doctor Explains What to Expect appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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399
When Your Spouse Says No to Microdosing: What Do You Do?
If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one: https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected]. The post When Your Spouse Says No to Microdosing: What Do You Do? appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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398
5 Years Later: My First Ever Guide to Microdosing Psilocybin
If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one: https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected]. The post 5 Years Later: My First Ever Guide to Microdosing Psilocybin appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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397
Microdosing & Neuroplasticity: Can the Brain Hold Onto the Changes?
If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one: https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected]. The post Microdosing & Neuroplasticity: Can the Brain Hold Onto the Changes? appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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396
Microdosing & Maternal Health: What the Science Says About Pregnancy, Breastfeeding & Parenting
If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one: https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected]. The post Microdosing & Maternal Health: What the Science Says About Pregnancy, Breastfeeding & Parenting appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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395
I Ended My Anxiety Road Trip on a Nude Beach… Here’s What I Learned
If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one: https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected]. The post I Ended My Anxiety Road Trip on a Nude Beach… Here’s What I Learned appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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394
The Microdosing Experience: What It Feels Like and Why It Matters
If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one: https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected]. The post The Microdosing Experience: What It Feels Like and Why It Matters appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 15 – Marky Mark
If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one: https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected]. The post Day 15 – Marky Mark appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 14 – The Aging Hippie
If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one: https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected]. The post Day 14 – The Aging Hippie appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 13 – Nellie in Jersey City
If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one: https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected]. The post Day 13 – Nellie in Jersey City appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 12 – The Vietnamese Restaurant
The post Day 12 – The Vietnamese Restaurant appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 11 – Lou at The Diner
The post Day 11 – Lou at The Diner appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 10 – Dr. Dave in Maryland
The post Day 10 – Dr. Dave in Maryland appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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The Mycelial Network – How Mushrooms May Influence the Human Brain
The post The Mycelial Network – How Mushrooms May Influence the Human Brain appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 9 – The 91 Year Old Woman
The post Day 9 – The 91 Year Old Woman appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 8 – God Renewed His Mind
The post Day 8 – God Renewed His Mind appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 7 – Another Waitress
The post Day 7 – Another Waitress appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 6 – The Psychologist
The post Day 6 – The Psychologist appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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5 – The 29 Year Old Woman
The post 5 – The 29 Year Old Woman appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 4 – The 81 Year Old Man in the Restaurant
The post Day 4 – The 81 Year Old Man in the Restaurant appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Unintended Effects of Microdosing: Lessons From Real-World Experience
The post Unintended Effects of Microdosing: Lessons From Real-World Experience appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 3 – The Hotel Manager
The post Day 3 – The Hotel Manager appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 2 – The Woman in The Coffee Shop
The post Day 2 – The Woman in The Coffee Shop appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Day 1 – The Waitress
The post Day 1 – The Waitress appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Psilocybin and Neuroplasticity: A New Approach to Breaking Habits
The post Psilocybin and Neuroplasticity: A New Approach to Breaking Habits appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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The Anxiety Road Trip Begins
The post The Anxiety Road Trip Begins appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Functional Psilocybin: Beyond One Size Fits All Dosing
The post Functional Psilocybin: Beyond One Size Fits All Dosing appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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373
Why Apple and Spotify Hate Me More Than Ever
The post Why Apple and Spotify Hate Me More Than Ever appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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The Science of Psilocybin Dosing: Why One Size Doesn’t Fit All
The post The Science of Psilocybin Dosing: Why One Size Doesn’t Fit All appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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The Science Behind Daily Tadalafil: More Than You Think
The post The Science Behind Daily Tadalafil: More Than You Think appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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The Case for Low-Dose Psilocybin in Mental Health
The post The Case for Low-Dose Psilocybin in Mental Health appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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369
Psilocybin and Autoimmune Disease: A New Perspective
The post Psilocybin and Autoimmune Disease: A New Perspective appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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368
The Neuroscience of Psilocybin, Sleep, and Dreams
The post The Neuroscience of Psilocybin, Sleep, and Dreams appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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My Psychedelic Bike Ride
The post My Psychedelic Bike Ride appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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The Emerging Role of Psilocybin in Parkinson’s, Stroke, Lyme Disease, and Alzheimer’s Disease
The post The Emerging Role of Psilocybin in Parkinson’s, Stroke, Lyme Disease, and Alzheimer’s Disease appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Anxiety, Unhappiness and the Role of Psilocybin
The post Anxiety, Unhappiness and the Role of Psilocybin appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Is Psilocybin Too Risky?
The post Is Psilocybin Too Risky? appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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I Had Anxiety Every Day – Until I Tried THIS
The post I Had Anxiety Every Day – Until I Tried THIS appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Where Can I Buy Magic Mushrooms in 2026?
The post Where Can I Buy Magic Mushrooms in 2026? appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Why I Don’t Take Heroic Doses But Prefer Consistent Low Doses of Magic Mushrooms
The post Why I Don’t Take Heroic Doses But Prefer Consistent Low Doses of Magic Mushrooms appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Does Microdosing Really Work? 🔲 Yes 🔲 No
The post Does Microdosing Really Work? 🔲 Yes 🔲 No appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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I Want To Be Alone
The post I Want To Be Alone appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Can You Help Out a Bit? A Special Episode
The post Can You Help Out a Bit? A Special Episode appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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When Is It Safe to Microdose?
The post When Is It Safe to Microdose? appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Here’s Why I’m Sure Psilocybin Works
The post Here’s Why I’m Sure Psilocybin Works appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Every Woman’s Guide to Microdosing
The post Every Woman’s Guide to Microdosing appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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I May Have Lied To You
The post I May Have Lied To You appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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How to Feel Calmer
The post How to Feel Calmer appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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Panic Attack In Japan
The post Panic Attack In Japan appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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How to Finally Take Control Of Your Life
The post How to Finally Take Control Of Your Life appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.
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ABOUT THIS SHOW
My name is Dr. David Madow, and I’m the founder and host of Microdose U, a podcast focused on psilocybin microdosing for depression, anxiety, PTSD, and overall mental health. Not long ago, I was barely hanging on. Daily life was filled with fatigue, anxiety, depression, and a complete lack of motivation. I tried medications, psychotherapy, meditation, yoga, and everything else I was told might help. Nothing truly worked. Then I discovered psilocybin. Through Microdose U, I share my personal journey from the very beginning, along with real conversations, lived experience, and honest exploration of microdosing as a tool for healing and growth. This podcast is about hope, curiosity, and finding a way forward when traditional paths fall short. All content is shared for educational and informational purposes only. I am sharing my personal story and experiences, not giving medical advice. Always consult your healthcare provider and follow all local laws before using psychedelics.
HOSTED BY
Dr. David M. Madow
CATEGORIES
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