Microdose U - Psilocybin Microdosing for Depression and Anxiety podcast artwork

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Microdose U - Psilocybin Microdosing for Depression and Anxiety

My name is Dr. David Madow, and I’m the founder and host of Microdose U, a podcast focused on psilocybin microdosing for depression, anxiety, PTSD, and overall mental health. Not long ago, I was barely hanging on. Daily life was filled with fatigue, anxiety, depression, and a complete lack of motivation. I tried medications, psychotherapy, meditation, yoga, and everything else I was told might help. Nothing truly worked. Then I discovered psilocybin. Through Microdose U, I share my personal journey from the very beginning, along with real conversations, lived experience, and honest exploration of microdosing as a tool for healing and growth. This podcast is about hope, curiosity, and finding a way forward when traditional paths fall short. All content is shared for educational and informational purposes only. I am sharing my personal story and experiences, not giving medical advice. Always consult your healthcare provider and follow all local laws before using psychedelics.

Publisher-supplied feed metadata · PodParley refreshed May 20, 2026 · Source feed

  1. 400

    The 2027 Beginner’s Guide to Microdosing Psilocybin: A Doctor Explains What to Expect

    If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one:  https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected].   The post The 2027 Beginner’s Guide to Microdosing Psilocybin: A Doctor Explains What to Expect appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  2. 399

    When Your Spouse Says No to Microdosing: What Do You Do?

    If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one:  https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected].   The post When Your Spouse Says No to Microdosing: What Do You Do? appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  3. 398

    5 Years Later: My First Ever Guide to Microdosing Psilocybin

    If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one:  https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected].   The post 5 Years Later: My First Ever Guide to Microdosing Psilocybin appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  4. 397

    Microdosing & Neuroplasticity: Can the Brain Hold Onto the Changes?

    If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one:  https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected].   The post Microdosing & Neuroplasticity: Can the Brain Hold Onto the Changes? appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  5. 396

    Microdosing & Maternal Health: What the Science Says About Pregnancy, Breastfeeding & Parenting

    If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one:  https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected].   The post Microdosing & Maternal Health: What the Science Says About Pregnancy, Breastfeeding & Parenting appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  6. 395

    I Ended My Anxiety Road Trip on a Nude Beach… Here’s What I Learned

    If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one:  https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected].   The post I Ended My Anxiety Road Trip on a Nude Beach… Here’s What I Learned appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  7. 394

    The Microdosing Experience: What It Feels Like and Why It Matters

    If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one:  https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected].   The post The Microdosing Experience: What It Feels Like and Why It Matters appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  8. 393

    Day 15 – Marky Mark

    If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one:  https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected].   The post Day 15 – Marky Mark appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  9. 392

    Day 14 – The Aging Hippie

    If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one:  https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected].   The post Day 14 – The Aging Hippie appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  10. 391

    Day 13 – Nellie in Jersey City

    If this episode helped you in any way, don’t let the conversation end here. There’s a whole lot more waiting for you inside the Microdose U community. 1. JOIN US ON PATREON This is the #1 way to go deeper with Microdose U. Join our private community where we can have conversations that simply don’t happen on the podcast or YouTube. You’ll also be helping support Microdose U and allowing us to keep doing this work. If you only click one link, make it this one:  https://microdoseu.com/patreon/ 2. NEW TO MICRODOSING? START HERE Take our FREE 5-Day “Microdosing for Beginners” Email Course: https://dave-madow-com.kit.com/0cab14f591 3. MICRODOSE U More episodes, resources and information: https://microdoseU.com 4. THE MICRODOSE U AMAZON STORE Products that Dr. Dave personally uses and recommends: https://www.amazon.com/shop/microdoseu Nothing here is to be taken as medical advice. Dr. Dave is sharing his personal story with you. Please contact your healthcare professional to find out if this is right for you. Dr. Dave may be reached at [email protected].   The post Day 13 – Nellie in Jersey City appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  11. 390

    Day 12 – The Vietnamese Restaurant

      The post Day 12 – The Vietnamese Restaurant appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  12. 389

    Day 11 – Lou at The Diner

      The post Day 11 – Lou at The Diner appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  13. 388

    Day 10 – Dr. Dave in Maryland

      The post Day 10 – Dr. Dave in Maryland appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  14. 387

    The Mycelial Network – How Mushrooms May Influence the Human Brain

      The post The Mycelial Network – How Mushrooms May Influence the Human Brain appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  15. 386

    Day 9 – The 91 Year Old Woman

      The post Day 9 – The 91 Year Old Woman appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  16. 385

    Day 8 – God Renewed His Mind

      The post Day 8 – God Renewed His Mind appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  17. 384

    Day 7 – Another Waitress

      The post Day 7 – Another Waitress appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  18. 383

    Day 6 – The Psychologist

      The post Day 6 – The Psychologist appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  19. 382

    5 – The 29 Year Old Woman

      The post 5 – The 29 Year Old Woman appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  20. 381

    Day 4 – The 81 Year Old Man in the Restaurant

      The post Day 4 – The 81 Year Old Man in the Restaurant appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  21. 380

    Unintended Effects of Microdosing: Lessons From Real-World Experience

      The post Unintended Effects of Microdosing: Lessons From Real-World Experience appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  22. 379

    Day 3 – The Hotel Manager

      The post Day 3 – The Hotel Manager appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  23. 378

    Day 2 – The Woman in The Coffee Shop

    The post Day 2 – The Woman in The Coffee Shop appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  24. 377

    Day 1 – The Waitress

    The post Day 1 – The Waitress appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  25. 376

    Psilocybin and Neuroplasticity: A New Approach to Breaking Habits

    The post Psilocybin and Neuroplasticity: A New Approach to Breaking Habits appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  26. 375

    The Anxiety Road Trip Begins

    The post The Anxiety Road Trip Begins appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  27. 374

    Functional Psilocybin: Beyond One Size Fits All Dosing

    The post Functional Psilocybin: Beyond One Size Fits All Dosing appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  28. 373

    Why Apple and Spotify Hate Me More Than Ever

    The post Why Apple and Spotify Hate Me More Than Ever appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  29. 372

    The Science of Psilocybin Dosing: Why One Size Doesn’t Fit All

    The post The Science of Psilocybin Dosing: Why One Size Doesn’t Fit All appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  30. 371

    The Science Behind Daily Tadalafil: More Than You Think

    The post The Science Behind Daily Tadalafil: More Than You Think appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  31. 370

    The Case for Low-Dose Psilocybin in Mental Health

    The post The Case for Low-Dose Psilocybin in Mental Health appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  32. 369

    Psilocybin and Autoimmune Disease: A New Perspective

    The post Psilocybin and Autoimmune Disease: A New Perspective appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  33. 368

    The Neuroscience of Psilocybin, Sleep, and Dreams

    The post The Neuroscience of Psilocybin, Sleep, and Dreams appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  34. 367

    My Psychedelic Bike Ride

    The post My Psychedelic Bike Ride appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  35. 366

    The Emerging Role of Psilocybin in Parkinson’s, Stroke, Lyme Disease, and Alzheimer’s Disease

    The post The Emerging Role of Psilocybin in Parkinson’s, Stroke, Lyme Disease, and Alzheimer’s Disease appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  36. 365

    Anxiety, Unhappiness and the Role of Psilocybin

    The post Anxiety, Unhappiness and the Role of Psilocybin appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  37. 364

    Is Psilocybin Too Risky?

    The post Is Psilocybin Too Risky? appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  38. 363

    I Had Anxiety Every Day – Until I Tried THIS

    The post I Had Anxiety Every Day – Until I Tried THIS appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  39. 362

    Where Can I Buy Magic Mushrooms in 2026?

    The post Where Can I Buy Magic Mushrooms in 2026? appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  40. 361

    Why I Don’t Take Heroic Doses But Prefer Consistent Low Doses of Magic Mushrooms

    The post Why I Don’t Take Heroic Doses But Prefer Consistent Low Doses of Magic Mushrooms appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  41. 360

    Does Microdosing Really Work? 🔲 Yes 🔲 No

    The post Does Microdosing Really Work? 🔲 Yes 🔲 No appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  42. 359

    I Want To Be Alone

    The post I Want To Be Alone appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  43. 358

    Can You Help Out a Bit? A Special Episode

    The post Can You Help Out a Bit? A Special Episode appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  44. 357

    When Is It Safe to Microdose?

    The post When Is It Safe to Microdose? appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  45. 356

    Here’s Why I’m Sure Psilocybin Works

    The post Here’s Why I’m Sure Psilocybin Works appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  46. 355

    Every Woman’s Guide to Microdosing

    The post Every Woman’s Guide to Microdosing appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  47. 354

    I May Have Lied To You

    The post I May Have Lied To You appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  48. 353

    How to Feel Calmer

    The post How to Feel Calmer appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  49. 352

    Panic Attack In Japan

    The post Panic Attack In Japan appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

  50. 351

    How to Finally Take Control Of Your Life

    The post How to Finally Take Control Of Your Life appeared first on How Microdosing Psilocybin Can Rewire Your Brain From Depression and Anxiety.

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ABOUT THIS SHOW

My name is Dr. David Madow, and I’m the founder and host of Microdose U, a podcast focused on psilocybin microdosing for depression, anxiety, PTSD, and overall mental health. Not long ago, I was barely hanging on. Daily life was filled with fatigue, anxiety, depression, and a complete lack of motivation. I tried medications, psychotherapy, meditation, yoga, and everything else I was told might help. Nothing truly worked. Then I discovered psilocybin. Through Microdose U, I share my personal journey from the very beginning, along with real conversations, lived experience, and honest exploration of microdosing as a tool for healing and growth. This podcast is about hope, curiosity, and finding a way forward when traditional paths fall short. All content is shared for educational and informational purposes only. I am sharing my personal story and experiences, not giving medical advice. Always consult your healthcare provider and follow all local laws before using psychedelics.

HOSTED BY

Dr. David M. Madow

Frequently Asked Questions

How many episodes does Microdose U - Psilocybin Microdosing for Depression and Anxiety have?

Microdose U - Psilocybin Microdosing for Depression and Anxiety currently has 50 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.

What is Microdose U - Psilocybin Microdosing for Depression and Anxiety about?

My name is Dr. David Madow, and I’m the founder and host of Microdose U, a podcast focused on psilocybin microdosing for depression, anxiety, PTSD, and overall mental health. Not long ago, I was barely hanging on. Daily life was filled with fatigue, anxiety, depression, and a complete lack of...

How often does Microdose U - Psilocybin Microdosing for Depression and Anxiety release new episodes?

Microdose U - Psilocybin Microdosing for Depression and Anxiety has 50 episodes. Check the episode list to see recent publication dates and frequency.

Where can I listen to Microdose U - Psilocybin Microdosing for Depression and Anxiety?

You can listen to Microdose U - Psilocybin Microdosing for Depression and Anxiety on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.

Who hosts Microdose U - Psilocybin Microdosing for Depression and Anxiety?

Microdose U - Psilocybin Microdosing for Depression and Anxiety is created and hosted by Dr. David M. Madow.
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