PODCAST · science
Naked Genetics
by Naked Scientists
From plants to pathogens, fruit flies to fungi and hamsters to humans, Naked Genetics takes a look at the science of genes. With in-depth interviews, the latest news from the world of genetics, answers to your questions, and our gene of the month, tune in for a look inside your genes...
Episodes
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CRISPR: the cutting edge of gene editing
In this edition of Naked Genetics, we take a closer look at CRISPR gene editing. What is it? And what are the ethics involved in rewriting the human genome? Like this podcast? Please help us by supporting the Naked Scientists
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Debunking 'junk' DNA
In this episode of Naked Genetics: What new DNA techniques are revealing about human sacrifices in Mayan culture; we debunk the 'junk', in junk DNA; and, the upside down sea snail that makes rafts of its own snot... Like this podcast? Please help us by supporting the Naked Scientists
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Will It Sequence? Synthetic DNA
In this episode of Naked Genetics: How much of your personality is down to your DNA; we also look at synthetic DNA, and why we'd want to make it; plus, the spiders that turn one species of insect against its own kind... Like this podcast? Please help us by supporting the Naked Scientists
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Will It Sequence? 700-year-old DNA
In this episode of Naked Genetics: A mammoth discovery in ancient DNA structure; on the subject of ancient DNA, what can we sequence for a centuries old body? And, in quirks of evolution, the animal that drinks its own offspring's blood... Like this podcast? Please help us by supporting the Naked...
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Will It Sequence: How effective is handwashing?
In this episode of Naked Genetics: The risk factors between schizophrenia and substance use disorder have had a fresh genetic examination; I put Illumina to the test and ask, 'what difference does washing our hands really make?' And, the the extraordinary way in which dung beetles use the night…
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Will It Sequence? What grows on your food?
In this episode of Naked Genetics: What the latest genetics research has to say about restless leg syndrome; I put Illumina to the test and ask, 'what really grows on our food?'; And, what makes a tardigrade so tough? Like this podcast? Please help us by supporting the Naked Scientists
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Will It Sequence? Hunting drug resistant bugs
In this month's edition of Naked Genetics: Why a genetic bottleneck created decades ago means some whales are in deep water; how wastewater is helping genetic sequencer track down deadly diseases; And, surf's up! how one beach dwelling creature is shredding the gnar in order to find food... Like...
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ADHD advantages, and mining microbiomes
This episode of Naked Genetics: has the evolutionary advantage to ADHD been uncovered? Also, We look at the microbiome of mining. And, the only vertebrate in the world that would thank you for saying that it looked like crap... Like this podcast? Please help us by supporting the Naked Scientists
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The roamin' Roman Empire, and Charles Darwin's love life
In this edition of Naked Genetics: The surprising findings of a roman empire diversity study; Are hybrid animals the way out of the biodiversity crisis? And, was charles darwin as romantic as he was scientifically brilliant? Like this podcast? Please help us by supporting the Naked Scientists
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The origin of Europe's MS disease, and South Pole sequencing
This episode of Naked Genetics, the origins of multiple sclerosis markers in northern Europe is revealed, and why it might have helped more people than it hindered; we also look at organisms surviving in Earth's most extreme conditions; and ask just why might a bunch of organisms be turning into...
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Testing for genetic diseases, and bats with big penises
This episode of Naked Genetics, we catch up with our genetics experts and look into the hot button genetics news; we look at how genetics affects our genes, and how genes affect our ageing; and, another extraordinary mating ritual in Quirks of Evolution... Like this podcast? Please help us by...
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Is vegetarianism genetic, and the penis-eating spider
This episode, we catch up with some of the more curious genetics news from the past month including how much Neanderthal is in you and how that affects your risk of disease. Also, we look at one of the most remarkable breeding strategies in the animal kingdom, a spider with two penises that eats...
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COVID In Your Genes: The Risk Factors
Do our genes control how we respond to COVID? The question has been nagging at the world since the pandemic began. Now we have the answer - and it's yes. In this programme, geneticist Nathan Pearson uncovers the specific bits of DNA that make you more likely to catch coronavirus, as well as the...
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The Genes Who Came in for the Cold
How do we cope at the extremes of low temperature? Across the world, groups of people have historically made their home in icy and inhospitable landscapes... and even today, groups of thrill seekers push their bodies to the limits by going swimming in water close to freezing. In this month's...
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How To Tell Coronavirus Variants Apart
We're looking at the most critical variants of the coronavirus, and finding out how to tell whether they're flummoxing COVID vaccines. Plus: the cost of catching a serial killer; DNA with four strands instead of two; and a mutant fish whose fins have started turning into limbs! Like this podcast?...
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Identical Twins: Not Identical?
Meet the small DNA differences that make their mark by existing in the magical period of early development. We'll hear how mutations in the very first stages of human embryos have bizarre consequences for identical twins; and how even earlier in the process, sperm use selfish genes to get ahead…
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RNA vaccines, privacy, and penguins
The first group of people in the world have received a 'genetic' vaccine against the coronavirus. What is it, and how does it work? Naked Scientist Chris Smith breaks it down and addresses your concerns. Plus, why some genes have to change rapidly just to stay the same; a new way to keep…
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Mink, Ivory, & a Disease Discovered Backwards
It's a regular Noah's Ark: from the coronavirus strains that have been spreading through minks, to a new DNA test that can track poached elephant ivory, to the genetics of a very useful - and very inbred - cat. Plus: scientists have discovered a brand new genetic disease, via an unlikely approach...
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Slave Trade, Neanderthals, & COVID
This week: a risk factor for severe COVID that comes from Neanderthals; using genes to track the millions transported as slaves across the Atlantic; a doctor runs through the list of what coronavirus mutations are worth watching out for; and learning population genetics from a video game... Like...
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How To Survive Poison
This week, a message from Naked Scientists listener Loretta. "I'm curious if your show might cover some of the most interesting case studies of organisms developing tolerance to severe toxins, what genetic insight this gives us about adaptation and natural selection more broadly, and what some of...
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The Inner Lives of Birds
Tweet tweet! We're talking birds, and the incredible things they can do. Today we're spotlighting five of the coolest recent stories in bird genetics: hummingbirds powering their lightning-fast flight; a gene that controls migration; why males have different colours to females; how light…
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Female Mosaicism: The Stronger Sex?
The same thing that makes the patchwork colours on a tortoiseshell cat, also - according to some - is why human females live longer, see colour better, and even more often survive the coronavirus. It's all thanks to having two X chromosomes. Females compensate by switching one of them off, and…
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Fermented foods: the real deal?
We take a look at the trendy world of fermented foods. Are they actually good for you? And if so, why? Plus, the latest genetics news: from bacteria that live inside cancer cells, to gene sequencing the dead sea scrolls... Like this podcast? Please help us by supporting the Naked Scientists
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ACE2: The Coronavirus Gateway
Are you one of the many people who take ACE inhibitors or ARBs to treat high blood pressure? Or to help with heart issues or diabetes? In the UK, this is about one in seven people, making these are some of the most common prescription drugs out there; and recently there have been worries that…
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The Coronavirus Mutation Situation
In this episode we're taking apart the tiny creature behind this global pandemic. From how looking at the genes of the coronavirus can help figure out the animal it comes from; to the exact ways it's spreading around the world; and even how a hidden mutation is threatening to lead vaccine-makers…
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Gene Genealogy & The Lost Family
One of the biggest tech booms of the past half decade has been direct to consumer DNA tests. The results come in the post, and with them come both answers and new questions: questions that tens of thousands of people now have to figure out how to ask. In this episode, a new book from journalist...
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FOXG1 Syndrome: Fighting the Odds
Listener Vivek got in touch with a question about a rare genetic disease his son has, called FOXG1 Syndrone. In fact, it's so rare - and so newly-discovered - that only about six hundred people in the world have been diagnosed. Kids with FOXG1 have severe developmental delays; in Vivek's words,...
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The Fly Infest-agation
We got a Christmas present from listener Anna: a small plastic tube full of dead flies. They've recently been infesting the hospital where she works. She wants us to figure out what they are, and what caused the infestation. Can DNA crack the case? Plus, the return of Gins & Genes... Like this...
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African genetics and ethics
There are very few African studies in genetics. Most of the existing data are based on Europeans. This is why a number of institutions have collaborated to survey thousands of people's genomes in rural Uganda. In this episode we cover the results of Africa's biggest ever genetics study; and the...
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What's in the water?
This month we're diving into the stuff that makes up two thirds of the Earth's surface. Can you use genetics to figure out what's in the water? We put the science to the test by making a geneticist guess our mystery fish. Plus, a story about whales and dolphins: what do you lose when you leave…
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Quadrillions: Sequencing the UK Biobank
Half a million genomes. That's how many the UK Biobank has, stored as blood samples in freezers up in Manchester. And in September 2019 they announced a project to sequence every single one of them. It's the obvious next step for the UK Biobank, the research study that began in 2006 and now...
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The Dog Show
It's a doggy dog world... in this episode we're talking pugs, bulldogs, and French bulldogs. They've all been bred for flat faces, but their airways haven't shrunk alongside their skulls - meaning that they often struggle to breathe. How has this happened? After evolving for millions of years…
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Mendel's Trick
Naked Genetics is back with new episodes every month! Today we're taking a step back. Where does genetics actually come from? How did we get to today's world of genome sequences and gene editing? It all started with an 19th-Century monk, working in his garden - but who was he really, and how did…
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Decoding a Mammoth with George Church
Join Harvard DNA pioneer George Church and Chris Smith in conversation as they discuss gene cloning, DNA sequencing, decoding the mammoth genome, the risks posed by fossil viruses lurking in extinct genomes, the prospects of xenotransplantation and safety of gene therapy, and the risks of human...
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The future of forensic genetics
We're returning to the scene of the crime with another look at the latest techniques in the world of forensic genetics - can we really predict physical features or even ethnicity from your DNA, and what does this mean for our criminal justice system? Plus, is the 'CSI effect' real? And our gene…
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A Festival of Genomics
We're off to a festival - but before you worry about where your tent and wellies are, it's the Festival of Genomics, held at a clean and dry conference centre in London rather than a muddy field full of rock bands and dodgy burgers. Plus, what does the public really think of genetic technology?…
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Crime scene genes
It's CSI Naked Genetics, as we find out how genetic technology is used to solve crimes.
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Back to the womb
We take a trip back to the womb and before, to find out about early development. Plus, the importance of placentas, why the age of your womb rather than your eggs matters, and a video game-inspired gene of the month.
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The future of genomic medicine
This month we're finding out how genetic advances are shaping the future of healthcare at the Genetics Society autumn meeting. Plus, signposts for bees and an operatic gene of the month.
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Matchmaking at the zoo
This month we're off to the zoo to meet some lovelorn laughing thrushes, endangered snails, and the Cilla Black of Sumatran Tigers. Plus, a sneak preview of this year's Genetics Society JBS Haldane lecture, and a gene of the month that likes a tipple.
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Evolution's luxury item
You're a mammal. I'm a mammal. Your pet cat or dog is a mammal, as are whales, lemurs, pandas and polar bears. But what exactly is a mammal, and what can our genes tell us about our evolution? Plus, school students take on the whipworm genome, the surprising genetic diversity of Papua New Guinea,...
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Exposing the contents of your genes
Would you ever consider donating your genome to research? We meet a man who has, and find out why. Plus, we get our hands dirty in the search for new antibiotics, take a look at the ethics of human gene editing, and our gene of the month is getting ahead in life.
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Store, write, edit
As scientists announce that they have used CRISPR technology to fix a faulty gene in a human embryo - not for the first time, but more accurately than ever before - we take a look at storing, writing and editing in DNA. Plus, our gene of the month is all ears.
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Genes and dementia
This month we're taking a look at the role that genes play in dementia, and finding out how researchers are using this knowledge to develop urgently-needed treatments. Plus, a big release of big data from the UK Biobank, and our gene of the month is an expert swordsman.
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Bees, trees and 3-D genes
This month we're literally getting inside our genes, as we explore chromosomes through a 3-dimensional virtual reality art, music and science project. Plus, researchers are turning to bees, trees and more in search of new genetic systems, and our gene of the month has been around for a while.
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Tackling tumours, curing cancer
This month we're zooming in on cancer, finding out how researchers are tackling tumours in unprecedented detail. Plus, our gene of the month is the guardian of your genome, rather than the galaxy.
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Battle of the sexes
We might joke about the battle of the sexes, but it turns out that this is actually true - at least for a hundred or so imprinted genes. Plus, what opossums can teach us about sex, reporting back from a very special scientific meeting, and a superhero-styled gene of the month.
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Putting genomics to work
The DNA sequencing revolution is providing ever more data about genomes from all kinds of species, from humans to bacteria. But how do we make sense of it all? Who gets their hands on it? And how do we use it to benefit patients? We meet the scientists developing new computer tools to analyse and...
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Science and the single cell
Our bodies are made up of trillions of cells - but these aren't mere biological building blocks, as inert as bricks. They're constantly communicating and changing. So how do scientists measure this? Plus, you can now take part in an international survey about genetics knowledge, a GIANT study...
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Genes, laws and Brexit
We hear a lot about genetic modification and how it's being used to improve agriculture. But who decides whether modified crops can be grown? Do new gene editing techniques like CRISPR count as GM? And what happens to these regulations when the UK leaves the EU? Plus, our gene of the month comes...
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ABOUT THIS SHOW
From plants to pathogens, fruit flies to fungi and hamsters to humans, Naked Genetics takes a look at the science of genes. With in-depth interviews, the latest news from the world of genetics, answers to your questions, and our gene of the month, tune in for a look inside your genes...
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Naked Scientists
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