Naked Scientists Special Editions ENHANCED

The Ancient Greeks understood that the liver was one of the most incredible organs humans possess when they wrote the cautionary tale of Zeus' punishment of Prometheus, in which poor Prometheus was tied to a rock where an eagle would eat his liver every day, but overnight it would regenerate and grow back, allowing his punishment to continue day after day. Now, in real life, the liver doesn't regenerate quite that quickly, but it is true that it has the ability to grow back and heal itself remarkably well. Georgia Mills spoke to liver scientist Auinash Kalsotra from the University of Illinois,... Like this podcast? Please help us by supporting the Naked Scientists

Biological systems are able to create complex shapes and patterns, like the stripes of a zebra, the shape of your hand or the dynamic displays of a flock of birds. These shapes develop in an emergent and self-organised way, relying on just local interactions between individuals. In contrast, human designed technology is usually created by an external builder. But now, a team of roboticists and biologists have come together to design robot swarms that can self-organise into complex shapes. Hannah Laeverenz Schologelhofer spoke with Sabine Hauert from the Bristol Robotics Lab. Like this podcast? Please help us by supporting the Naked Scientists

Cervical cancer is one of the most common cancers affecting young women, and it's caused by a virus called Human Papilloma Virus, or HPV, which is spread through sexual contact. The virus causes the cells of the cervix to keeping growing excessively, which eventually damages their DNA, causing cancer. Testing for this cancer can be challenging: these days it involves using DNA tests to look for traces of the virus in a sample. But the viruses are very common, and only a small proportion of people carrying them will actually get cancer; so there are lots of false positives. Now researchers at... Like this podcast? Please help us by supporting the Naked Scientists

In this episode of the eLife Podcast, the nerves with a taste for salt, why fur seal pups succumb to hookworms, the oldest fossilised flowers ever found, the monkey business of chimp personalities, and the 11 million year old flying squirrel foung in a rubbish tip... Get the references and the transcripts for this programme from the Naked Scientists website

Christmas is a wonderful time of year, but all of the additional transport and consumption adds up, and we are left with plenty of seasonal rubbish and greenhouse gases. So how can you cut down this Christmas? Georgia Mills is here to spoil all of the festive fun... Like this podcast? Please help us by supporting the Naked Scientists

Clean water is something that we often take for granted, but making it can be a major technological and energy-intensive process. Now, thanks to a system developed by scientists at York University, Toronto, and MIT, there might be a way to do this much more cheaply in future. Hannah Laeverenz Schlogelhofer spoke with York researcher Thomas Cooper, about this new way of using sunlight to clean up water and produce superheated steam. Like this podcast? Please help us by supporting the Naked Scientists

How can seemingly similar cells behave differently? This is a particularly important question when a small change means that a cell does not function properly and several diseases might be the result of these small changes at the single cell level. But a cell is a complex system, and some of the important molecules inside a cell exist in very small quantities that can be difficult to detect. To address this challenge, a new tool has been developed called 'nano-tweezers'. These tiny devices can extract individual molecules from inside cells. Hannah Laeverenz Schlogelhofer spoke with Joshua Edel... Like this podcast? Please help us by supporting the Naked Scientists

Language is all around us, and good language skills are important for getting on in life. But does being good in one language domain, like spelling, mean you'll be good in another, like grammar? And if your child is doing well with language as a toddler, will they still be doing well as a teenager? Recently, results have come out from a study 15 years in the making and Katie Haylor spoke to one of the authors, Rebecca Pearson from the University of Bristol. Like this podcast? Please help us by supporting the Naked Scientists

When we think of robots we might think of the Terminator, West World, or even something completely different like Big Hero Six - a story about a young boy and his soft medical robot companion Baymax. Doughy and malleable, a robot like Baymax is kind of the holy grail for scientists who are working on making Soft Robots - robots which aren't made of metal or plastic but instead of stretchable, supple materials like rubber, gels, or fabric. Eva Higginbotham spoke to Ilse Van Meerbeek, a PhD student at Cornell University who recently published a paper in Science Robotics about new progress in... Like this podcast? Please help us by supporting the Naked Scientists

Every year, hundreds of millions of people contract malaria; this is a parasitic infection spread by mosquitoes. The parasite does two things when it grows in the body: either it clones itself to make millions more malaria parasites in that infected individual, and makes them sicker in the process; or, it produces a different form of the parasite that's sexually active and specialised to infect mosquitoes so it can spread to another human. And this week scientists in Edinburgh have discovered that malaria bases the decision on whether to boost its numbers in an infected person, or to try to... Like this podcast? Please help us by supporting the Naked Scientists

Do you like to lie out on the beach in the summer, or are you more likely to be found hiding in the shade? Well, how you answer might depend on how quickly you seem to get sunburnt. We all know that we should wear sunscreen when out and about in the summer to protect our skin and so reduce our risk of skin cancer, but new research from the Weill Medical College of Cornell might allow us to ditch the sunscreen at some point in the future. Eva Higginbotham spoke to Dr Jonathan Zippin, a dermatologist and skin researcher, about his lab's key discovery in the science of skin. Like this podcast? Please help us by supporting the Naked Scientists

When we think of our immune system, most of us will be familiar with the white blood cells that circulate around our body to target and kill the bacteria and viruses that make us sick. But, we actually also have a special type of immune cell sitting in some of our body surfaces, like our skin and our gut, and new research suggests that these cells might hold the key to future cancer and allergy treatments. Eva Higginbotham spoke to Professor Adrian Hayday from the Francis Crick Institute and King's College London, about his new paper describing the unique way these cells actually work, and why... Like this podcast? Please help us by supporting the Naked Scientists

The wildlife impact of urban sprawl, how climate change will affect the distribution of mosquito-borne outbreaks, Devil Facial Tumour Disease 2, how LSD works in the brain and gender bias in peer review all go under the microscope in this latest episode of the eLife Podcast. Get the references and the transcripts for this programme from the Naked Scientists website

Today marks 100 years since the end of World War 1. This conflict caused the deaths of around 16 million people, and the new developments in artillery meant that new and nasty injuries were defying our ability to treat them. Ironically, this meant WW1 actually lead to huge advances in medicine, and neuroscience. But, thanks to a charity, Headway, it's also helping people with brain injuries today. Georgia Mills has been finding out how Like this podcast? Please help us by supporting the Naked Scientists

We get so many good questions sent to us here at The Naked Scientists, that sadly we can't fit them all into our monthly question and answer shows. So here's an extra slice of science for you from our November 2018 QnA. Roger got in touch to ask whether artificial intelligence will be making medicines in the future, and we also heard from Sean about some rather intelligent ravens... Like this podcast? Please help us by supporting the Naked Scientists

Glioblastoma is an aggressive and often deadly cancer of the brain. Understanding it is vital to improving patient outcomes. In a new study published in Nature Genetics, a group in Cornell University has been sequencing genes to understand which ones are switched on by the tumours. To learn more, Adam Murphy spoke to Charles Danko, of the Baker Institute for Animal Health and the Cornell College of Veterinary Medicine... Like this podcast? Please help us by supporting the Naked Scientists

Good dental hygiene is crucial in the fight against gum disease, which can lead to a common condition called periodontitis. It comes about when changes to the bacteria in the mouth cause a reaction called inflammation in areas around the teeth, potentially destroying tissue and bone and causing tooth loss. But quite why an altered microbiome causes this inflammation isn't known, so there are no targeted treatments, and surgery is the main option for severe cases. But now scientists have spotted that periodontitis patients have higher numbers of immune cells called TH17 cells in their mouths,... Like this podcast? Please help us by supporting the Naked Scientists

Astronomers at the University of Hertfordshire have come up with an explanation for the wobble seen in jets of matter being blasted from regions surrounding some supermassive black holes: Another nearby supermassive black hole! Dr Martin Krause tells us how we can see them at all... Like this podcast? Please help us by supporting the Naked Scientists

Nowadays, tuberculosis takes more lives than any other infectious disease. Cases are on the decline but emerging antibiotic resistance threatens to interrupt that pattern. Tamsin Bell spoke with Professor Francois Balloux from University College London to learn about how this infectious disease evolved... Like this podcast? Please help us by supporting the Naked Scientists

We all know that drinking alcohol is bad for us but in the UK we still pay a huge 3.5 billion annually for the National Health Service (NHS) to treat over 60 alcohol induced medical conditions including liver disease, pancreatitis, diabetes, heart disease and numerous forms of cancer. Fortunately, it seems that the message to put down the booze has trickled down to the younger generation as a recent study of 16 to 24 year olds shows that over the past ten years, they are drinking less. Tamsin Bell spoke to Linda Ng Fat from University College London to find out why more teens are laying off... Like this podcast? Please help us by supporting the Naked Scientists

From right here on earth to the furthest visible parts of the universe, NASA has its eye on pretty much everything in between. Professor Andrew Coates from University College London was lead co-investigator in the joint ESA-NASA Cassini-Huygens mission to Saturn, and is involved in several further NASA missions of space exploration. With NASA turning 60 this month, Sam Brown spoke to Professor Coates about the fascinating missions that NASA is involved with, and what they have planned for the future... Like this podcast? Please help us by supporting the Naked Scientists

This special edition of the eLife Podcast marks our 50th episode and we've decided to mark the milestone by focusing on a field that's huge and tiny both at the same time: huge in terms of the rate at which the discipline's growing and the impact it's set to have our lives, and tiny because its subjects are microscopic. It's our microbiome, the community of micro-organisms that live on us and in us and outnumber our own human cells by maybe 50 fold: we're literally passengers in our own bodies, and over the next 30 minutes we'll hear how gut bacteria might alter your risk of diabetes, and how... Get the references and the transcripts for this programme from the Naked Scientists website

Mosquitoes spread diseases like malaria, and they are rapidly becoming resistant to the insecticides used to control them. So scientists are looking at the potential of using a genetic technique, called a gene drive, to solve the problem. This involves engineering a gene-editing system into the insects that targets and inactivates a gene called dbx - or doublesex - that is needed for the insects to develop normally. Critically though, only female mosquitoes, which are also the ones that bite, are affected by the change. This means that males are left unaffected and can spread the genetic... Like this podcast? Please help us by supporting the Naked Scientists

Antibiotic resistance is one of the greatest threats facing mankind today. A new group in the University of Washington in Seattle, have been working to fight this threat. In a new study, they've been looking to poison bacteria using the heavy metal gallium, to improve the lives of those with cystic fibrosis. Adam Murphy spoke to two authors of the study. First, Christopher Goss and then colleague, Pradeep Singh... Like this podcast? Please help us by supporting the Naked Scientists

Imagine going into space. You've got your kit, you're blasted into darkness, you're ready to discover the unknown but then your equipment doesn't quite fit the task required. How can you prepare for that? This is a reality that space engineers and robotic experts are trying to facing every day. Now, researchers from Yale think they've got an answer. They've developed something called "Omniskin" - a sheet of material that can animate everyday objects and turn them into robots. Izzie Clarke spoke to study author Joran Booth. Like this podcast? Please help us by supporting the Naked Scientists

You may have heard of graphene, the so called wonder material set to revolutionise electronics but the difficulty to consistently add extra properties and scale up cheaply limits industrial use! Scientists have been looking for easy to make alternatives, such as a new class of materials called metal organic frameworks or MOFs. As the name suggests, they're made by combining two components: a metal and something called an "organic chain" which contains carbon with some other elements. These can be used to create new materials with exciting properties.The big problem is that scientists have not... Like this podcast? Please help us by supporting the Naked Scientists

Do you share food or do you bite the hand off anyone who tries? Chimpanzees, one of our closest relatives are in the latter category: they'll gladly share tools, but food's a no no. New research published in Proceedings of the Royal Society B has been looking into our other close relatives: bonobo apes. Bizarrely, while they'll gladly share food, woe betide anyone who touches someone else's tools or toys! So what does this say about us? Adam Murphy spoke to Christopher Krupenye, from the University of St. Andrews to learn more. Like this podcast? Please help us by supporting the Naked Scientists

We've all been there at some point - you raise your hand in class, answer the question, and get it utterly, utterly wrong. These school-day humiliations may stay with us many years later, in fact - I'd love to hear yours, but as our kids are all headed back to school this week, we're trying to find out if perhaps these mistakes are good for us! Georgia Mills is on the case, but only after finding out some of our listeners biggest dunce moments! Like this podcast? Please help us by supporting the Naked Scientists

These days, many of us are heavily dependent on our trusty sat navs to get where we want to go, but looking at these devices whilst driving is incredibly dangerous and can lead to car accidents. Psychologists from Anglia Ruskin University are hoping to minimise the dangers of using this technology by incorporating audio cues with in-car GPS to forewarn the driver of the lay of the land. Tamsin Bell met with Helen Keyes to hear what's driving their work... Like this podcast? Please help us by supporting the Naked Scientists

Goats can tell apart human facial expressions and - what's more - prefer to interact with happy people, according to a new study from scientists at Queen Mary University of London. We knew work animals like dogs and horses could do this, but no-one knew if animals domesticated for food products would be able to. Georgia Mills spoke to lead researcher Alan McElligott to find out how they did it Like this podcast? Please help us by supporting the Naked Scientists

Most of the people who develop cancer are adults, although a significant number of children succumb too. The signs are though that childhood cancers could have a different origin than the adult disease, which might also mean they can be treated in a different way. Cambridge University's Sam Behjati suspects that tumours in children form from foetal tissue that has failed to mature properly. And by comparing the genetic instructions operating in normal and cancerous kidney cells from children and adults, he's tracked down evidence to support his theory and found a host of new avenues to explore... Like this podcast? Please help us by supporting the Naked Scientists

From artificial photosynthesis to the art of statistics, the Naked Scientists take Jenny Zhang and Richard Samworth, two of St John's College's leading scientists, for a trip down the river to hear all about their work. Like this podcast? Please help us by supporting the Naked Scientists

In this episode of the eLife Podcast, we hear about the RNA world, bovine TB, lung fibrosis, and why rock pigeons have different wing patterns... Get the references and the transcripts for this programme from the Naked Scientists website

Since Darwin's time scientists have been studying the skeleton of a type of fish that lived 400 million years ago called Heterostracans. These fish were covered in a tough exoskeleton, but scientists couldn't decide exactly where it came from. Was it a precursor to bone? To teeth? New research is suggesting all those old theories may be as dead and buried as the fish fossils, and this exoskeleton is just another way of making bone. Adam Murphy spoke to Joseph Keating of the University of Manchester to learn more... Like this podcast? Please help us by supporting the Naked Scientists

HIV is a global pandemic. Worldwide, about 37 million people are living with the virus, and there are between 3 and 5 thousand AIDS deaths every day. More worrying is that, despite intensive public health and safe sex campaigns, there are a further 3 to 5 thousand new HIV infections occurring every day, and despite decades of effort, scientists still have not yet managed to develop an effective vaccine. But one very powerful way to prevent infection is for men to be circumcised, which reduces their risk of picking up the virus by up to 80%. So is this a cost effective strategy to halt HIV... Like this podcast? Please help us by supporting the Naked Scientists

Mixing chemicals together causes reactions and produces new molecules. With so many different chemicals in existence, there are infinite combinations that can be made, and millions of chemical reactions yet to be tried. But doing these tests is very time consuming, laborious and has a low success rate; it's also very susceptible to human failings, like bias and fatigue. To surmount this, University of Glasgow chemist Lee Cronin has invented a robot to test his chemical combinations for him. What's more impressive is that this robot can actually learn. By testing random chemical combinations... Like this podcast? Please help us by supporting the Naked Scientists

Vitiligo is an autoimmune condition, in which the immune system attacks the pigment-producing cells of the skin, leaving behind pale white patches. Although not dangerous in itself, vitiligo can be disfiguring, causing a great deal of distress to people suffering from it. There are treatments available for vitiligo - these include topical creams that suppress the immune attack on skin cells, and phototherapy, which uses UV light. However, these treatments are time- and effort-consuming, particularly if large areas of the skin are affected. Another problem is that they only work temporarily -... Like this podcast? Please help us by supporting the Naked Scientists

Heart attacks come about when blood vessels in the heart are blocked, and without a supply of oxygen-rich blood, the heart muscle can die. This is called ischemic injury, and can also occur in other places in the body, potentially leading to tissue death and even limb amputation. But what if it was possible to re-build the blood vessels in the heart or in other areas of the body, to kick-start the circulation and prevent tissues from being starved of oxygen, and dying? This is what Jo Mountford is trying to do at the Scottish National Blood Transfusion service, as she explains to Katie... Like this podcast? Please help us by supporting the Naked Scientists

In this episode of the eLife Podcast, signs that trees exchange genes over hundreds of kilometres, how our gut bacteria protect us from plant toxins, and new insights into the placebo effect... Get the references and the transcripts for this programme from the Naked Scientists website

People all around the world are living the high life. That's to say, living their whole lives at high altitude. This lifestyle has an impact on their bodies, including upon how their bones grow. And one adaptation, Cambridge University's Stephanie Payne has found, is to alter the relative lengths of the arms. Katie Haylor and Chris Smith found out more... Like this podcast? Please help us by supporting the Naked Scientists

Scientists want to raise awareness to protect the Earth from dangerous asteroids. June 30th has now become Asteroid Day where people from around the world come together to learn about asteroids, the impact hazard they may pose, and what we can do to protect our planet, families, communities, and future generations from future asteroid impacts. Izzie Clarke spoke to Matt Bothwell and Adrian Currie at the University of Cambridge to learn more... Like this podcast? Please help us by supporting the Naked Scientists

4 billion years ago, life on earth looked nothing like it does today. In fact, the oceans contained only single-celled microbes. At some point, these single-celled organisms began to work together, forming complex, multi-celled creatures, which then suddenly became much larger. The question is, why? Emily Mitchell studies one of the earliest animals believed to exist, and explained to Marika Ottman why she thinks these creatures got bigger when they did Like this podcast? Please help us by supporting the Naked Scientists

In recent years, we've woken up to the massive problem that is dementia. This is where people progressively lose their cognitive faculties and Alzheimer's Disease is one well-known example. But scientists are increasingly realising that injury done to the brain by damaged blood vessels is probably the leading cause of dementia, but it's also the one that we know much less about. It happens when the very small blood vessels deep within the brain become narrowed, stiffened and leaky, which leads to progressive damage to the adjacent brain tissue, although we don't understand how this happens, or... Like this podcast? Please help us by supporting the Naked Scientists

Osteoarthritis, a condition which damages the cartilage in joints, is a painful, debilitating condition. Millions suffer every year, and with an ageing population, that number will only increase. Therefore, improving diagnosis is an important goal. Adam Murphy spoke with Tom Turmezei from Cambridge University, to learn more about osteoarthritis and his Wellcome Trust funded project which aims to improve diagnosis... Like this podcast? Please help us by supporting the Naked Scientists

If robots really are the future, then said future is certainly one step closer as of this week. For the first time ever, a robot has been used in surgery on the human eye. To find out more about this incredible feat of engineering, Isabelle Cochrane spoke to Dr Tom Edwards, the lead author of the study... Like this podcast? Please help us by supporting the Naked Scientists

CRISPR makes it possible to snip out undesired bits of DNA from our cells. This process holds the potential to cure genetic conditions such as cystic fibrosis. However, it seems that doing this isn't without risk. Marika Ottman went to the University of Cambridge and spoke with biochemist Jussi Taipale to learn more... Like this podcast? Please help us by supporting the Naked Scientists

Researchers have found a way to regenerate the enamel - or apatite - that's damaged by tooth decay. Katie Haylor spoke to Alvaro Mata from Queen Mary University of London...Sound effects from www.zapsplat.com Like this podcast? Please help us by supporting the Naked Scientists

We know more about the surface of mars than we do about the depths of our own ocean, but scientists from the California Academy of Science created an invention that allows researchers to bring never-before seen species from coral reefs in the deep sea to the ocean's surface. In the spirit of World Ocean's day tomorrow, Marika Ottman spoke with lead author Bart Shepherd to learn more... Like this podcast? Please help us by supporting the Naked Scientists

Millions suffer from osteoarthritis, a condition that causes joints, especially knee and hip joints, to become stiff and painful. Luckily these joints can be replaced by an implant with usually good results. However, scientists are going one step further, bringing robots into the operating theatre to improve precision, and patient outcomes. The Nuffield Hospital in Cambridge recently brought in one of these robot helpers, and Chris Smith spoke with the director of the hospital, Adrian Connolly... Like this podcast? Please help us by supporting the Naked Scientists

In this eLife Podcast, echolocation in bats, chemical probes for open science, using aspirin to manage TB meningitis, brain topography, and combining science and parenthood... Get the references and the transcripts for this programme from the Naked Scientists website