PODCAST · science
Neurology: Disease Deep Dive
by Practical Neurology
The field of neurology is vast and complex. This series provides thorough conversations with key expert physicians on neurologic conditions including the evolution of our understanding and treatment of these conditions.
Episodes
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Rethinking Multiple Sclerosis: A New Biologic Framework for MS Progression
Daniel Ontaneda, MD, PhD, Cleveland Clinic, Cleveland, OH, explains why traditional labels such as relapsing-remitting, secondary progressive, and primary progressive multiple sclerosis (MS) may not fully reflect the underlying biology of the disease and why a more dynamic framework could better...
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Tavapadon Treatment for Early Parkinson Disease: Findings from the TEMPO Trials
Hubert Fernandez, MD, Cleveland Clinic, Cleveland, OH, discusses findings from the TEMPO trials evaluating tavapadon, a selective dopamine D1/D5 receptor partial agonist, as monotherapy in early Parkinson disease and as an adjunct to levodopa in patients with motor fluctuations. He examines...
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Could a Novel Oral Therapy Change How Clinicians Treat Obstructive Sleep Apnea? Insights From the SynAIRgy Trial
In this episode, Patrick J. Strollo Jr, MD, FACP, FCCP, FAASM, of the University of Pittsburgh Department of Medicine, Pittsburgh, PA, discusses the data from the phase 3 SynAIRgy clinical trial for AD109, an investigational once-nightly oral treatment targeting neuromuscular dysfunction in...
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Part II: Early Alzheimer Disease Detection through a Davos Alzheimer's Collaborative Initiative: Lessons from Real-World Implementation
This episode explores the real-world implementation of the Davos Alzheimer’s Collaborative Healthcare System Preparedness (DAC-SP) US Early Detection Program at Virtua Health, examining outcomes in identifying cognitive impairment, streamlining referrals, and supporting efficient use of clinical...
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Part I: Early Alzheimer Disease Detection with the DAC-SP Blueprint Program: Overview of a Scalable Health System Approach
Elyse Perweiler, RN, MPP, Professor, Rowan–Virtua School of Osteopathic Medicine, Stratford, NJ, and Tim MacLeod, PhD, Program Director, Healthcare System Preparedness Program, Davos Alzheimer’s Collaborative (DAC), Toronto, Ontario, Canada, examine how health systems can operationalize early...
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Detecting Multiple Sclerosis Earlier: PRLs and the Evolving McDonald Diagnostic Criteria
This episode explores new evidence showing that paramagnetic rim lesions (PRLs) are highly prevalent early in multiple sclerosis (MS) and can differentiate MS from mimics with striking accuracy. Dr. Daniel Ontaneda, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, and Dr. Pascal Sati,...
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Modern Glioma Management: Integrating Molecular Markers and New Targeted Therapies
Patrick Y. Wen, MD, Dana-Farber Cancer Institute, Boston, MA, discusses current standards of care for low- and high-grade gliomas, including the importance of comprehensive molecular testing, the World Health Organization classification of tumors of the central nervous system, and newly available...
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Maturing with Migraine: Practical Guidelines for Transitioning Adolescent Migraine and Headache Patients into Adult Practice
Hope O’Brien, MD, MBA, FAHS, FAAN, Founder and CEO of the Headache Center of Hope, Cincinnati, OH, discusses challenges and considerations for adult headache neurologists who are onboarding adolescent patients as they transition from pediatric practice. Dr. O’Brien highlights a framework with...
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Advances in ALS: New Targets, Trials, and Care Strategies
Merit Cudkowicz, MD, Julieanne Professor of Neurology, Harvard Medical School, Boston, MA, discusses the evolving landscape of treatment for ALS, including FDA-approved disease-modifying therapies, the importance of genetic testing, the emergence of gene therapies, and the promising clinical…
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Cerebrovascular Inflammatory Conditions: Diagnostic Challenges and Treatment Considerations
Abbas Kharal, MD, MPH, Neurologist at Cleveland Clinic Neurological Institute, Cleveland, OH, provides a review of cerebrovascular inflammatory conditions, with an emphasis on diagnostic challenges, the evolving treatment landscape, and the use of imaging and clinical responses to assist…
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The Evolving Therapeutic Landscape for Parkinson Disease
Mark Stacy, MD, William E. Murray Professor of Neurology, Medical University of South Carolina, Charleston, SC, discusses the evolving therapeutic landscape for Parkinson disease, highlighting promising advances in neuroprotective therapies, biomarkers, personalized medicine, and innovative...
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Advances in the Evaluation of TBI
Welcome to Neurology: Disease Deep Dive. In this episode, Dr. Beth McQuiston, MD, RD, Medical Director at Abbott Laboratories, and Dr. David Okonkwo, MD, PhD, Professor of Neurological Surgery, Clinical Director of the Brain Trauma Research Center, and Director of the Neurotrauma Program at...
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NMOSD Part 3 - Overview of treatment, including goals, triggers, and considerations for switching therapies
In this series, Derrick Robertson, MD, Director of the Multiple Sclerosis Division at the University of Southern Florida discusses multiple aspects of NMOSD. Dr. Robertson is talking with us today on behalf of Horizon Therapeutics which is compensating him for his services and is sponsoring this...
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NMOSD Part 2 - The importance and tools for monitoring NMOSD, and signs, symptoms and evaluation of disease activity
In this series, Derrick Robertson, MD, Director of the Multiple Sclerosis Division at the University of Southern Florida discusses multiple aspects of NMOSD. Dr. Robertson is talking with us today on behalf of Horizon Therapeutics which is compensating him for his services and is sponsoring this...
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NMOSD Part 1 - Overview and important considerations for diagnosis
In this series, Derrick Robertson, MD, Director of the Multiple Sclerosis Division at the University of Southern Florida discusses multiple aspects of NMOSD. Dr. Robertson is talking with us today on behalf of Horizon Therapeutics which is compensating him for his services and is sponsoring this...
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Narcolepsy, Idiopathic Hypersomnia, and General Sleep Disorders
In this episode, Rajkumar Dasgupta, MD, Clinical Associate Professor at Keck School of Medicine of USC and sleep specialist, provides an in-depth review of what's new in sleep disorders, with a special focus on updates in narcolepsy and idiopathic hypersomnia.
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Frequently Asked Questions
How many episodes does Neurology: Disease Deep Dive have?
Neurology: Disease Deep Dive currently has 16 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is Neurology: Disease Deep Dive about?
The field of neurology is vast and complex. This series provides thorough conversations with key expert physicians on neurologic conditions including the evolution of our understanding and treatment of these conditions.
How often does Neurology: Disease Deep Dive release new episodes?
Neurology: Disease Deep Dive has 16 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to Neurology: Disease Deep Dive?
You can listen to Neurology: Disease Deep Dive on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts Neurology: Disease Deep Dive?
Neurology: Disease Deep Dive is created and hosted by Practical Neurology.
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